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Poster No. 0574<br />

The Effect of C-DIM12 on Mitigating the Development of<br />

Inflammation in Cultured Equine Chondrocytes and Synoviocytes<br />

John Alexander Schwartz, Mary Afzali, William H. Hanneman,<br />

C Wayne McIlwraith, Laurie R. Goodrich<br />

Poster No. 0575<br />

Linking Chondrogenesis And Inflammation Through The<br />

Smad Linker Domain<br />

Guus G. Van den Akker, Henk Van Beuningen, Elly Vitters,<br />

Esmeralda N. Blaney Davidson, Peter Van der Kraan<br />

Poster No. 0576<br />

Responses of Infrapatellar Fat Pad and Synovial Tissue to<br />

Cytokine Stimulation In Vitro<br />

Aaron M. Stoker, Catherine Jones, James Cook<br />

Poster No. 0577<br />

Responses of Osteoarthritic Osteochondral Tissue to Cytokine<br />

Stimulation In Vitro<br />

Nicole C. Werner, Aaron M. Stoker, Chantelle C. Bozynski, B. Sonny Bal,<br />

James L. Cook<br />

Poster No. 0583<br />

Transthyretin Deposition Accelerates the Development of<br />

Experimental Osteoarthritis in Mice<br />

Tokio Matsuzaki, Oscar Alvarez-Garcia, Yukio Akasaki, Natalia Reixach,<br />

Joel Buxbaum, Martin K. Lotz<br />

Poster No. 0584<br />

Differential DNA Methylation and Reduced Expression of Critical<br />

Transcription Factors in Human OA Cartilage<br />

Oscar Alvarez-Garcia, Kathleen M. Fisch, Ryuichiro Akagi, Andrew I. Su,<br />

Martin K. Lotz<br />

Poster No. 0585<br />

Suppression Of REDD1 In OA Cartilage, A Novel Mechanism for<br />

Dysregulated mTOR Activation<br />

Oscar Alvarez-Garcia, Ryuichiro Akagi, Yukio Akasaki, Kathleen M. Fisch,<br />

Andrew I. Su, Martin K. Lotz<br />

Poster No. 0586<br />

Suppression of Sestrins in Aging and Osteoarthritic Cartilage:<br />

Dysfunction of an Important Stress Defense Mechanism<br />

Tao Shen, Yan Li, Merissa Olmer, Oscar Alvarez-Garcia, Martin K. Lotz<br />

Poster No. 0578<br />

Assessment of Biomarker Production by Osteochondral Tissue<br />

Obtained from Patients Undergoing Total Knee Arthroplasty<br />

Nicole Werner, Aaron Stoker, James T. Stannard, B. Sonny Bal, James L. Cook<br />

Poster No. 0579<br />

Circulating and Synovial Fluid Inflammatory Cytokine Profiles<br />

in Primary Knee Osteoarthritis<br />

Sittisak Honsawek, Thomas Mabey, Aree Tanavalee, Pongsak Yuktanandana,<br />

Vinai Parkpian<br />

Poster No. 0580<br />

Inflammation Following an Intra-articular Fracture in a<br />

Large Animal Model of PTOA<br />

Jessica E. Goetz, Erik Cole, Emily B. Petersen, Gail Kurriger,<br />

Douglas C. Fredericks, James A. Martin<br />

Poster No. 0581<br />

The Relationship Between Synovial Inflammation, Structural<br />

Joint Pathology And Pain In Post-traumatic Osteoarthritis: The<br />

Effect Of Treatment With Intra-articular Stem Cells Versus a<br />

Hyaluronan Hexadecylamide-derivative<br />

Christopher B. Little, Cindy C. Shu, Varshini Ravi, Susan M. Smith,<br />

Antonella Schiavinato, Margaret M. Smith<br />

Poster No. 0582<br />

Biologic Agents Improve The Abnormality Apoptosis of Synovial<br />

Tissues In Rheumatoid Arthritis?<br />

Yuya Takakubo, Hiroharu Ohki, Kan Sasaki, Yasunobu Tamaki, Yasushi Naganuma,<br />

Michiaki Takagi<br />

PS1<br />

Cartilage, Synovium & Osteoarthritis—<br />

Osteoarthritis—Clinical<br />

Poster No. 0587<br />

A Pragmatic Knee Preservation Registry to Follow Patients With<br />

Degenerative Joint Disease and Determine Utility of Synovial<br />

Fluid Biomarkers to Inform Treatment Decisions<br />

Stephen Yu, Hans-Georg Wisniewski, Elisha Lee, Thomas Deakin,<br />

Xiang Sean Zhou, Raj Karia, Eric Strauss, Laith Jazrawi, Richard Iorio, Philip Band<br />

Poster No. 0588<br />

Pain and Loss of Function Correlates with Changes in Joint<br />

Morphology in Thumb CMC OA<br />

Joseph Trey Crisco, Tarpit Patel, Eni Halilaj, Douglas Moore, Amy Ladd,<br />

Arnold-Peter C. Weiss<br />

Poster No. 0589<br />

Real-time Estimation Of The External Knee Adduction Moment in<br />

Knee Osteoarthritis Using An Offaxis Elliptical Trainer<br />

Sang Hoon Kang, Song Joo Lee, Li-Qun Zhang<br />

Poster No. 0590<br />

Knee Joint Distraction Compared with High Tibial Osteotomy:<br />

A Randomized Controlled Trial<br />

Jan-Ton A. Van der Woude, Karen Wiegant, Ronald J. Van Heerwaarden,<br />

Sander Spruijt, Peter M. Van Roermund, Roel J. Custers, Simon C. Mastbergen,<br />

Floris P. Lafeber<br />

Poster No. 0591<br />

The Prevalence of Neurocognitive Dysfunction in Total Joint<br />

Arthroplasty and Relation to Patient Reported Outcomes<br />

Stephen Yu, Emmanuel Edusei, Kelsey Grossman, Raj Karia, David Steiger,<br />

James Slover<br />

POSTERS<br />

79

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