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PS1<br />

Spine—Disc, Tissue Engineering and Repair<br />

PS1<br />

Spine—Disc Biology<br />

Poster No. 0864<br />

Fabrication, Maturation, And Implantation of a Composite<br />

Tissue-engineered Total Disc Replacement<br />

Dong Hwa Kim, John T. Martin, Sarah E. Gullbrand, Christian G. Pfeifer,<br />

Dawn M. Elliott, Lachlan J. Smith, Harvey E. Smith, Robert L. Mauck<br />

Poster No. 0865<br />

Optimization of In Vitro Pre-culture Conditions To Maximize in<br />

Vivo Performance of Engineered Intervertebral Discs<br />

John T. Martin, Sarah Gullbrand, Beth G. Ashinsky, Dong Hwa Kim,<br />

Kensuke Ikuta, Lachlan J Smith, Dawn Elliott, Robert Mauck, Harvey Smith<br />

Poster No. 0866<br />

Self-Healing Dynamic Hydrogel for Nucleus Pulposus Restoration:<br />

Mechanical Characterization of Spine Motion Segments<br />

Marianna Peroglio, Adrián Pérez-San Vicente, Manuela Ernst, Pablo Casuso,<br />

Damien Dupin, Mauro Alini, David Eglin, Iraida Loinaz<br />

Poster No. 0867<br />

Genipin-crosslinked Fibrin has Potential for Use as a Cell Carrier<br />

for Annulus Fibrosus Repair<br />

Michelle A. Cruz, Olivia M. Torre, Robert K. Merrill, Svenja Illien-Junger,<br />

Andrew C. Hecht, James C. Iatridis<br />

Poster No. 0868<br />

Variations in Media Formulation Impact ECM Synthesis and<br />

Retention in NP Cell-laden HA Hydrogels<br />

Dong Hwa Kim, John T. Martin, Kensuke Ikuta, Harvey E. Smith, Dawn M. Elliott,<br />

Lachlan J. Smith, Robert L. Mauck<br />

Poster No. 0869<br />

In Situ Gelling Cellulosic Copolymer Hydrogels Restore<br />

Intervertebral Disc Height and Biomechanical Properties<br />

Post Nucleotomy<br />

Devika M. Varma, Huizi A. Lin, Rose G. Long, Andrew C. Hecht, James C. Iatridis,<br />

Steven B. Nicoll<br />

Poster No. 0870<br />

Mechanical Characterization of a Multi-Laminate,<br />

Angle-Ply Collagen Patch for Annulus Fibrosus Repair<br />

Ryan Borem, Sanjitpal Gill, Jeremy Mercuri<br />

Poster No. 0871<br />

Long Term Biocompatibility of Intradiscal Injections With<br />

Genipin in Ovine Model<br />

Matt Brown, John Racadio, Sharath Sundararaj, Tom Hedman<br />

Poster No. 0872<br />

A High Throughput Nucleus Pulposus Explant Culture System<br />

Preserves Tissue Integrity<br />

Timothy Jacobsen, Nadeen Chahine<br />

Poster No. 0874<br />

GDNF - But Not NGF - May Mediate Annulus Fibrosus Cell-Induced<br />

Neurite Outgrowth from Adult Dorsal Root Ganglia<br />

Hyunchul Kim, Niutish Bastani, Sameer Shah, Adam Hsieh<br />

Poster No. 0875<br />

Can Intradiscal Injection with TNF-α Inhibitor Reduce Pain and<br />

Disc Degeneration in a Rat Model?<br />

Hironobu Watanabe, Alon Lai, Michael Schuchman, Samuel K. Cho,<br />

Andrew C. Hecht, James C. Iatridis<br />

Poster No. 0876<br />

Longitudinal Bioluminescence Imaging reveals Advanced<br />

Glycation End-products upregulate NFκB in Intervertebral Discs<br />

Jennifer W. Liu, Simon Y. Tang<br />

Poster No. 0877<br />

Metabolic Responses of Annulus Fibrosis and Nucleus Pulposus<br />

to Pro-Inflammatory Stimuli<br />

James T. Stannard, Aaron M. Stoker, Theodore J. Choma, James L. Cook<br />

Poster No. 0878<br />

Tie2+ of the Bovine Coccygeal Discs are Multipotent Cells<br />

Capable to Differentiate into Osteogenic, Adipogenic and<br />

Chondrogenic Lineages<br />

Adel Tekari, Samantha CW Chan, Karin Wuertz, Daisuke Sakai, Lorin M Benneker,<br />

Sibylle Grad, Benjamin Gantenbein<br />

Poster No. 0879<br />

TonEBP (NFAT5)-Mediated Regulation of Pro-Inflammatory<br />

Molecules in Nucleus Pulposus in Response to Osmotic Stimulus<br />

Zariel I. Johnson, Irving M. Shapiro, Makarand V. Risbud<br />

Poster No. 0880<br />

Neurotropin Treatment Influence Ecm Production, Progenitor<br />

Cell Recruitment And Anti- Inflammatory Responses<br />

In Human Nucleus Pulposus Cells In Vitro<br />

Shunsuke Hiraishi, Daisuke Sakai, Tadashi Nukaga, Tomoko Nakai,<br />

Yoshihiko Nakamura, Joji Mochida<br />

Poster No. 0881<br />

The Difference Between the Effect of Omega-3 Fatty Acids and<br />

Indomethacin on the Responses of Intervertebral Disc Cells<br />

to Inflammation<br />

Zhongying Zhang<br />

Poster No. 0882<br />

Toll-like Receptor 2 Regulates Nerve Growth Factor Synthesis Via<br />

NF-κB Signaling in Intervertebral Disc Cells<br />

Emerson Krock, Joan B. Currie, Michael Weber, Jean A. Ouellet, Laura S. Stone,<br />

Derek H. Rosenzweig, Lisbet Haglund<br />

POSTERS<br />

Poster No. 0873<br />

Novel Biomaterials to Prevent Innervation: Implications to<br />

Reduce Painful Disc Degeneration<br />

Rebecca A. Wachs, Christine E. Schmidt<br />

Poster No. 0883<br />

Anti-degenerative Effect Of Selective c-f<br />

Fos/AP-1 Inhibitor, T-5224, For Mouse Intervertebral Discs<br />

Yasuhito Yahara, Shoji Seki, Hiroto Makino, Hiraku Motomura, Makiko Nogami,<br />

Shunichi Shiozawa, Noriyuki Tsumaki, Tomoatsu Kimura<br />

94

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