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THE DEATH of our drug safety monitoring capacity means more wasteful<br />

spending on drugs, and also that many more people will suffer and even<br />

die from the adverse effects of drugs—and that cost is incalculable.<br />

This is almost impossible to estimate but with<br />

dozens of FOI requests and efforts by government<br />

to stop releases, let’s say $125,000 to<br />

$150,000.<br />

• Settlements with Bob Hart, Ron Mattson,<br />

Malcolm Maclure, and Bill and Rebecca<br />

Warburton, modestly guesstimated at $250,000<br />

to $600,000.<br />

What does this add up to? Somewhere<br />

towards $10 million in public funds, though<br />

I could be way off (either way) on some of the<br />

staff time estimates and the settlements.<br />

But that is just the beginning of what this<br />

scandal has cost.<br />

For the bigger picture we’d have to consider<br />

all the delayed and cancelled research and<br />

evaluation projects that were either in progress<br />

or in the pipeline. If you dial things back to<br />

2011, PharmaCare had numerous drug safety<br />

evaluations in progress, looking at the safety<br />

of drugs for Alzheimer’s disease; smoking<br />

cessation drugs including Champix (considered<br />

so dangerous other jurisdictions in the<br />

world have stopped paying for it); Accutane,<br />

for acne (known to cause birth defects); antipsychotics<br />

(given to one-third of seniors in BC’s<br />

longterm care facilities in 2012/13); and new<br />

anticoagulants (very expensive drugs which<br />

are replacing Warfarin).<br />

The Alzheimer’s study has been completed<br />

but the government has yet to make a decision<br />

on whether to continue to fund these<br />

drugs, considered by most independent experts<br />

to be ineffective, and for some patients, intolerable<br />

and toxic. The three-year delay caused<br />

by the Ministry’s turmoil has meant three more<br />

years of profits for the companies and costs<br />

of probably $30 to $40 million for the taxpayer.<br />

Blood glucose test strips were also going to be<br />

re-evaluated but those studies were delayed<br />

for four years, meaning a waste of about<br />

$10 million per year, or about $40 million<br />

(new limits were placed on them in January<br />

2015). The cancellation of research on atypical<br />

antipsychotic use means both avoidable<br />

deaths each year plus other costs in the use of<br />

the drugs deemed toxic for many seniors, especially<br />

those with dementia—likely in the tens<br />

of millions.<br />

What are we up to now? It’s not a stretch<br />

to say that the cost of the scandal has been<br />

in excess of $100 million due mostly to delayed<br />

and cancelled research programs and halted<br />

policy changes.<br />

Perhaps the biggest frustration in this scandal<br />

is the sense of loss of what had been a worldclass<br />

capacity and willingness to evaluate drug<br />

safety in BC. With PharmaNet, our provincewide<br />

pharmacy database covering every<br />

soul in the province, we collect some of the<br />

most robust data in the country, meaning we<br />

can assess with a good deal of precision how<br />

well drugs are being tolerated. Yet with the<br />

ongoing chill over the Ministry, very few independent<br />

drug safety evaluations are being<br />

carried out. In fact the Research and Evidence<br />

Development branch at PharmaCare was<br />

destroyed and has never been restarted.<br />

So the math only goes so far in capturing<br />

the impact of this scandal.<br />

Is it acceptable that PharmaCare, a government<br />

agency that spends over $1.4 billion per<br />

year of public money on drugs, is overseen by<br />

a government with a chronic habit of siding<br />

with the pharmaceutical industry (and which<br />

receives political donations from them)? Is it<br />

acceptable that government has failed to revamp<br />

important evaluation studies that are measuring<br />

the population effects of the drugs it pays for?<br />

The loss to our health system—which I’m<br />

pegging at perhaps $100 million dollars—may<br />

some day be fully accounted for. The death<br />

of our drug safety monitoring capacity means<br />

more wasteful spending on drugs, and also<br />

that many more people will suffer and even<br />

die from the adverse effects of drugs—and<br />

that cost is incalculable.<br />

I admit that my back-of-the-envelope calculations<br />

may be wildly off, but let me ask you,<br />

dear readers: Do you have any data to help<br />

me make those calculations more accurate?<br />

Do you work in the Ministry of Health? Do<br />

you have any hard numbers I could put into<br />

my spreadsheet? More importantly, do you<br />

know who initiated the firings and why? Please<br />

contact me. Brown envelopes most welcome.<br />

Alan Cassels is a drug policy<br />

researcher and author in Victoria.<br />

He attended the press briefing<br />

in September 2012 when the<br />

scandal was announced to the<br />

world, and has been following<br />

the saga ever since.<br />

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www.focusonline.ca • February 2016<br />

19

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