Posters - NCDEU: An Annual Meeting Sponsored by ASCP

Wednesday, May 30, 2012
9:30 am – 10:30 am Plenary - A New NIH Focus on Research to
Facilitate Clinical Research
Frank Lloyd Wright Salon E-F
Chair: William Z. Potter, M.D., Ph.D., Neuroscience Steering Committee,
FNIH
Translational Therapeutics Development at NIH
Christopher P. Austin, M.D., National Center for
Advancing Translational Science
The explosion in mechanistic understanding of
human physiology in health and disease, exemplified
by the Human Genome Project and its successors,
has provided a deluge of potential new targets for
therapeutic development. At the same time, evolution
of technologies and operational systems for drug
discovery has allowed investigators and institutions
in the public sector to contribute directly to new
therapeutics discovery in a more vigorous way,
particularly for rare and neglected diseases. Over the
last decade, the NIH has built a variety of programs
which complement drug discovery efforts in the
biopharmaceutical sector, principally in two areas: (a)
science, technology, tool, and paradigm development
to improve scientific understanding and efficiency
of the therapeutics discovery process, and (b) early
stage drug development programs to de-risk projects
particularly for rare and neglected diseases, making
them more amenable to biopharmaceutical adoption
despite their low expected return on investment. The
mission and accomplishments of these programs will
be discussed.
10:30 am – 10:45 am Coffee Break
Frank Lloyd Wright Ballroom Foyer
42