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of therapy and also underlines the importance of duration of therapy (3 and 6 months). The study demonstrated that an increase of seminal carnitine and glucosidase positively impacted upon the patient progressive sperm motility. Supported by: Sigma-tau HealthScience provided Proxeed Plus product for the study. P-512 Wednesday, October 19, 2016 POTENTIAL IMPACT OF THE CAP-SCORE TESTÔ ON CLINICAL PREGNANCY AND MEDICAL COSTS IN COUPLES WITH UNEX- PLAINED INFERTILITY. J. B. Babigumira, a F. Sharara, b L. P. Garrison. c a Global Health, University of Washington, Seattle, WA; b Virginia Center for Reproductive Medicine, Reston, VA; c Pharmacy, University of Washington, Seattle, WA. OBJECTIVE: Sperm capacitation is a necessary precursor to fertilization. The Cap-ScoreÔ was developed to assess the capacitation status of men. This enables personalized management of infertility for some couples by selecting among timed intra-uterine insemination (IUI), versus moving immediately to in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in those with a low Cap-ScoreÔ. The objective P-513 Wednesday, October 19, 2016 SOURCES OF KNOWLEDGE AND EFFECT OF EDUCATION ON UROLOGISTS’ ATTITUDES TOWARDS PENILE TRANSPLANTATION. B. B. Najari, a P. V. Bach, b A. Bolyakov, a R. Lischer, a D. Paduch. c a Urology, Weill Cornell Medical College, New York, NY; b Weill Cornell Medical College, New York, NY; c Dept of Urology, Weill Cornell Medical College, New York, NY. OBJECTIVE: While penile transplantation (PT) has long been surgically feasible, only two such procedures have been performed worldwide. Despite the potential for improved quality of life in men who have experienced genitourinary trauma, there is a dearth of information regarding barriers to implementation of PT programs. Our objective was to evaluate the source of knowledge and effect of education on urologists’ attitudes towards PT. DESIGN: Online Survey. MATERIALS AND METHODS: An online survey was sent to members of the American Urological Association (AUA) using the SurveyMonkey platform. Respondents were asked from what sources they had learned about PT. Respondents were also asked if they are in favor of (1) organ transplantation in general, (2) transplantation of visceral organs that prolong life (i.e. kidney), (3) transplantation of organs that improve quality of life (i.e. face), Table of Parameter Estimates used in the Model Parameter Baseline Estimate Sensitivity Range Reference Costs (all 2016 $US) IUI $2,550 $1,275 — $3,825 Expert (+/- 50% SR) IVF-ICSI $15,000 $7,500 — $22,500 Expert (+/- 50% SR) Pregnancy Probabilities IUI in SOC 0.125 0.100 — 0.150 Expert (+/- 20% SR) IUI after Cap-Score 0.400 0.320 — 0.480 Expert (+/- 20% SR) IVF-ICSI 0.519 0.415 — 0.632 SART weighted mean for 35 — 37 (+/- 20% SR) Low Cap Score 0.385 0.308 — 0.462 Travis et al. poster (+/- 20% SR) of this study was to estimate the differences in clinical pregnancy rates and medical costs comparing the use of the Cap-ScoreÔ with timed IUI (CS-TI) and the current standard of care (SOC), namely 3 IUI cycles followed by 3 IVF-ICSI cycles. DESIGN: Decision-analytic modeling. MATERIALS AND METHODS: We developed and parameterized a decision-analytic model of management of unexplained infertility for a hypothetical woman 35 to 37 years of age, using her own eggs, based on data from published and unpublished sources. Model parameters are shown in the table. We calculated the clinical pregnancy rates and medical costs comparing CS-TI and SOC. We conducted univariate sensitivity analyses. The test has not yet been launched, and no price has been established, so the medical costs include only other costs. RESULTS: Compared to SOC, CS-TI is projected to increase the cumulative pregnancy rate by 1.7% (94.2% vs. 92.5%). This increase varies from 0.8% to 3.2% depending on the assumed pregnancy success rate of IVF. Compared to SOC, CS-TI is projected to reduce mean medical costs by $4,621 ($19,319 vs. $23,941). Sensitivity analysis places the range of this cost reduction from $2,700 to $6,500 per individual patient depending on the costs of IVF-ICSI. CS-TI is projected to reduce mean IUI costs by $715 ($6,734 vs. $6,019) and mean IVF-ICSI costs by $3,906 ($17,207 vs. $13,301) compared to SOC. CONCLUSIONS: Use of the Cap-ScoreÔ to personalize management of couples with unexplained infertility is projected to result in higher clinical pregnancy rates and reduced medical costs. References: 1. Society of Assisted Reproductive Technology (SART). Accessed on 05/01/2016 at https://www.sartcorsonline.com. 2. Travis JT, Cordona C, Moody MA, Simpson AJ, Seaman EK, Ostermeir: Consistent Differences Among Men in Capacitation Timing Could Personalize IUI/ART. Poster Presentation. Supported by: Androvia Life Sciences. and (4) PT. The responses ranged from ‘‘Extremely in favor (1)’’ to ‘‘Not at all in favor (5)’’. The PT question was repeated after reading a book excerpt about soldiers’ concerns about genitourinary trauma. RESULTS: Two hundred twenty eight urologists responded to the survey. Only 75 people (32.9%) had learned about PT from a professional health source (scientific journal, professional colleage, or formal lecture). One hundred twenty six (55.3%) of respondents had learned about PT from the mass media and 45 (19.7%) had no knowledge of PT. At baseline, the participants were significantly less if favor of PT [mean (SD) 2.4 (1.2)], than other forms of organ transplant (Table). After reading the book excerpt, attitudes toward PT significantly improved to 2.2 (1.1), p
likely to have ever been employed by the armed forces (32.7% vs 11.7%, p
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Supplement to: VOL. 106 NO. 3S SEPT
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The first six papers are candidates
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in follicular fluid from small antr
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MATERIALS AND METHODS: Letrozole/FS
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expulsion rates were 3.7% for both
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exposure continues to be a major pu
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were no statistically significant d
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References: 1. Br€annstr€om M,
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O-38 Monday, October 17, 2016 11:30
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the embryo was based solely upon th
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ART: CLINICAL 1 O-49 Monday, Octobe
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Odds of Term LBW According to Vario
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ETof male vs. female embryos: patie
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Differences in Outcomes between Day
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eaching the blastocyst stage by Day
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TIMING OF FERTILITY PRESERVATION Va
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References: 1. McLaughlin T, Lamend
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chromosomal status of embryos and,
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OBJECTIVE: To longitudinally assess
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clinical parameters as well as the
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sought out medical tourism in the C
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animals between 7 and 13 days and t
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MALE REPRODUCTION AND UROLOGY: CLIN
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O-114 Tuesday, October 18, 2016 12:
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P on quantitative immunoblotting co
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mated on day 28 post-BMT. In a sepa
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decreased but DETs were predominant
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OBJECTIVE: To evaluate pregnancy an
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pregnancy, live birth rate and misc
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Day 3 ‘‘no result’’embryos
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financial support, mostly from fami
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G. D. Palermo. Reproductive Medicin
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OUTCOME PREDICTORS: ART 2 O-169 Tue
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and the X 2 test was used for categ
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Table 1. Fresh vs. elective FET in
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Table 1: SA Parameters and Cycle Ty
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(ANOVA) of the degree and distribut
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line stem cells referred to ovarian
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that patients with EGT have poor GU
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microvessel density (MVD) of breast
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step of culture significantly impro
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syndrome and other chromosome abnor
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ate while minimizing the multiple b
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CLINICAL REPRODUCTIVE LABORATORY O-
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14. Ombelet W, Vandeput H, Van de P
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Mean 12-month costs in 2014 $ (SD)
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(HMB) and tumor size. We report the
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RESULTS: Gross inspection of the tr
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RESULTS: A total of 39,643 cycles b
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stimulation (p
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eSET with 1 embryo frozen No. Live
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previously demonstrated, in our mou
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(25%). Fertilization and cleavage r
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MATERIALS AND METHODS: 197 men from
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to respond and offer support and re
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questionnaire. Baseline demographic
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DESIGN: Descriptive analysis of bas
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(IFU) accompanying the demonstratio
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(0.3, 2.9), and median (IQR) BW was
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Elecsys ¼ 2,650 ng/ml with 95% CI
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AFC, and NOR. Women were further ca
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which is believed to be due to the
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y blastomere or blastocyst sampling
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P-62 Tuesday, October 18, 2016 INFE
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Current State of OT with Cryopreser
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P-73 Tuesday, October 18, 2016 A NO
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efficiency and wider variation in p
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DESIGN: This ongoing retrospective
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maternal age, ovulation trigger dru
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Table 1. Fresh vs. Freeze-all in po
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P-101 Tuesday, October 18, 2016 THE
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vs 43%, 78/183, respectively). With
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P-110 Tuesday, October 18, 2016 COR
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P-116 Tuesday, October 18, 2016 EVO
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OBJECTIVE: To determine if embryo m
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3:3, 4:2, 5:1, and 6:0). A euploid
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aberration respectively; direct cyt
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RESULTS: 1,417 families were analyz
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CONCLUSIONS: This report details a
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DESIGN: Retrospective data analysis
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4. Vaccari, S., J. Conaghan, and P.
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P-161 Tuesday, October 18, 2016 TOT
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Risks of Adverse Outcomes Compared
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CONCLUSIONS: Even though all study
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P-178 Tuesday, October 18, 2016 ARE
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c Physician, Kiryat Ono, Israel; d
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DESIGN: This was a multicentre retr
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Live Birth Rates (LBR, %) and Multi
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on first-trimester ultrasound were
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Outcomes by number of blastocysts i
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P-209 Tuesday, October 18, 2016 OOC
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Demographic Characteristics and Lab
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numbers. We have also analyzed the
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Table 1: There is no difference in
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15 to 51 oocytes is -0.004 (95% CI
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AGE and improvement of pregnancy ra
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CONCLUSIONS: Despite similar embryo
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CONCLUSIONS: Despite prior speculat
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P-249 Tuesday, October 18, 2016 CLI
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P-254 Tuesday, October 18, 2016 DOE
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Live singleton births after fresh v
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Patients with a second STEET after
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Differences in Outcomes between Day
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to be higher too. This study shatte
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culture with 1000 nM E 2 . These re
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MATERIALS AND METHODS: Women with r
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flow; Group B (n¼394): with increa
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P-296 Tuesday, October 18, 2016 IDE
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in their isthmocele that was remove
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RESULTS: CE of RS-ost is summarized
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consecutive cases were made during
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OBJECTIVE: To evaluate reproductive
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A: 43 %1% (n¼101) // >4% (n¼235)
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of the patients. In the same period
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factor (group 1A, malesyears old),
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K. B. Bjugstad, e K. Khalafalla, f
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16% had unpaired XY. Only 25% of sp
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genomic hybridization (aCGH). Copy
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treatment parameters. Age and FSH a
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absorptiometry (DXA) allows for hig
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transfer of three or more morpholog
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OBJECTIVE: Recently high powered st
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Page 251 and 252: young adult female monkeys. Am J Ph
Page 253 and 254: of oligo-ovulation in some patients
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Page 259 and 260: and had a live birth in the last tw
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Page 267 and 268: telomere length, telomere aggregate
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Page 271 and 272: DESIGN: This prospective single-cen
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Page 279 and 280: assigned to their matched controls.
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Page 291 and 292: OBJECTIVE: The growing interest in
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Page 297 and 298: MATERIALS AND METHODS: Healthy men
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Page 303 and 304: may be most apropos in patients wit
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Page 309 and 310: Direct division from 1 to 3 cells e
Page 311 and 312: 5. Spandorfer SD, Clarke R, Bovis L
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Page 339 and 340: I. Kang, b T. K. Yoon, b H. Song. a
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were made using Prism software. Stu
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CONCLUSIONS: Faster progression to
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using a time-lapse embryo monitorin
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drops may stress embryos and could
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trophectoderm biopsy and analyzed v
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abnormal and these zygotes should b
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P-678 Wednesday, October 19, 2016 G
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knocked-down TP53 in two WT hESC li
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Doctors should be able to help tran
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2004-2013 White Asian Black Hispani
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compared with the PGD group. Chromo
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P-705 Wednesday, October 19, 2016 G
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lastocysts), was calculated at 50%,
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MATERIALS AND METHODS: The patient
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AUTHOR INDEX Abbas, A., P-303, P-30
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Camargo, M., P-505 Camarillo, D. B.
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Fernandez, I., O-115 Fernandez, P.,
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Ismail, A. M., P-235, P-400, P-415
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Lo, K., O-153 Lonczak, A., O-56 Lon
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Palmor, M., P-161 Palomaki, G. E.,
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Sharma, P. A., P-359 Sharma, R., O-
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Wesselink, A., O-195 Wessels, C. E.
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P-404, P-405, P-408, P-409, P-411,
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Berro, R. Berwald, T. Bjugstad, K.
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Feinberg, R. F. Fields, R. A. Foida
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Leone Roberti Maggiore, U. DEKA, Sp
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Ready, K. Counsyl, Full-time compan
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Wells, D. Reprogenetics UK, Direct
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