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SATURDAY 29 OC<strong>TO</strong>BER 2016 SYMPOSIA<br />
Co-chairs: Mark Woodhead (United Kingdom), James Mpunga (Malawi)<br />
10.30 The epidemiology of TB in north west England and its relationship with poverty – Peter Macpherson (United Kingdom)<br />
10.50 The role of whole genome sequencing in detecting and reducing onward transmission of TB in England – Paul Cleary (United Kingdom)<br />
11.10 The role of the multi-disciplinary team and TB cohort review in reaching underserved groups – Jennifer Walker (United Kingdom)<br />
11.30 Patients’ perceptions of barriers to accessing TB care and involvement of civil society in TB strategy – Mango Hoto (United Kingdom)<br />
11:50 Discussion<br />
SYMPOSIUM 43 3 10:30-12:00 3 SESSION ROOM 11B<br />
NOVEL QUANTITATIVE APPROACHES IN PAEDIATRIC TUBERCULOSIS<br />
Section: Adult & Child Lung Health<br />
The development and application of new quantitative methods to deal with the challenges of interpreting notification data for childhood TB has helped<br />
increase attention in this area, and spur further work on evidence review, mortality estimates and the impact of interventions. At the same time,<br />
modelling can play a role earlier on in the intervention development pipeline, helping optimise treatments and suggest new approaches to diagnosis.<br />
We aim to provide an overview of the use of modelling and other novel quantitative methods in the area of paediatric TB and raise awareness<br />
of their potential.<br />
Co-chairs: James Seddon (United Kingdom), Courtney Yuen (United States of America)<br />
10.30 Childhood TB case-fatality and implications for mortality estimates – Helen E Jenkins (United States of America)<br />
10.45 Modelling to determine optimal dosing in treating paediatric TB meningitis – Rada Savic (United States of America)<br />
11.00 Modelling the cost-effectiveness of household contact screening for children – Anna Mandalakas (United States of America)<br />
11.15 Host bio-signatures for TB diagnosis: analytical challenges and future directions – Myrsini Kaforou (United Kingdom)<br />
11.30 The potential impact of BCG vaccine shortfalls on childhood mortality – Rebecca C Harris (United Kingdom)<br />
11.45 Discussion<br />
SYMPOSIUM 44 3 10:30-12:00 3 SESSION ROOM 11A<br />
BIOSAFETY AND TUBERCULOSIS INFECTION CONTROL:<br />
SHARING KNOWLEDGE, CHALLENGES AND SOLUTIONS IN TB LABORA<strong>TO</strong>RIES<br />
Section: Tuberculosis/Bacteriology & Immunology<br />
Biosafety in TB laboratories varies widely. Significant investment has been made in infrastructure upgrades, particularly at reference laboratory levels.<br />
Many countries have unsafe working environments (microscopy/Xpert to culture to DST). Even where upgraded, adequate operation and maintenance<br />
of biosafety equipment (BSCs, centrifuges, HVAC systems), and provision of PPE (respirators, gloves, etc.) is lacking. This session will highlight<br />
effective approaches to solving issues that laboratories face and demonstrate synergy of biosafety with infection control. Target audience: clinicians,<br />
laboratorians, national TB programme staff, and Ministry of Health officials, maintenance experts, biosafety professionals, or service and lab managers<br />
Co-chairs: Alaine Umubyeyi Nyaruhirira (South Africa), Paul Jensen (United States of America)<br />
10.30 Overview of the risk assessment approach: story of implementation – Christopher Gilpin (Switzerland)<br />
10.45 Biosafety and infection control in TB laboratories: challenges and solutions – Paul Jensen (United States of America)<br />
11.00 Challenges and solutions to constructions and maintenance of safe TB culture labs in Africa: end user perspective from Uganda –<br />
Moses Joloba (Uganda)<br />
11.15 Primary containment devices: their application, operation and maintenance – Jeff Serle (United States of America)<br />
11.30 Evolution of the TB laboratory in Vladimir Oblast, Russia – Grigory Volchenkov (Russian Federation)<br />
11.45 Discussion<br />
SYMPOSIUM 45 3 10:30-12:00 3 SESSION ROOM 11C<br />
ADHERENCE <strong>TO</strong> CONFRONT RESISTANCE:<br />
SOCIAL AND BEHAVIOURAL INTERVENTIONS IN LATIN AMERICA<br />
SATURDAY 29 OCT<br />
Sub-section: Tuberculosis/Nurses & Allied Professionals<br />
The special socio-cultural contexts in Latin America where people share unique social structures and cultural norms, lead to special challenges<br />
for TB control, especially in the area of treatment. Stigma plays an important role at societal, programmatic and even governmental levels. In addition,<br />
family dynamics, social support, and socio-economic status directly influence access and adherence. Understanding these issues and designing<br />
26-29 OC<strong>TO</strong>BER 2016 - LIVERPOOL - UNITED KINGDOM<br />
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