Understanding and predicting dose dependent and idiosyncratic events
12-07-2016-1330-Paul-Watkins-YES
12-07-2016-1330-Paul-Watkins-YES
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FDA Submission: A New Antibiotic<br />
that Caused Serum ALT Elevations<br />
in Phase 1 Study<br />
X X X<br />
Serum<br />
biomarkers<br />
ccK18<br />
CK18<br />
Oxidized<br />
HMGB1<br />
No acetylated<br />
HMGB1<br />
interpretation apoptosis<br />
41