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4 Scientific activity 48 8. Martínez-Hervas S, Martínez-Barquero V, Nuñez Savall E, Lendínez V, Olivares L, Benito E, Real JT, Chaves FJ, Ascaso JF. [Plasma IL-18 levels are related to insulin and are modulated by IL-18 gene polymorphisms].Clin Investig Arterioscler. 2015 Nov-Dec ;27(6):265-71.IF: 0 9. Mendez MM, Folgado J, Tormo C, Artero A, Ascaso M, Martínez-Hervás S, Chaves FJ, Ascaso JF, Real JT. Altered glutathione system is associated with the presence of distal symmetric peripheral polyneuropathy in type 2 diabetic subjects.J Diabetes Complications. 2015 Sep-Oct ;29(7):923- 7.IF: 3,005 10. Marrachelli V, Monleón D, Morales JM, Rentero P, Martínez F, Chaves FJ, Martín-Escudero JC, Redon J. 6C.04: INTEGRATED SNP ANALYSIS AND METABOLOMIC PROFILES OF METABOLIC SYNDROME.J Hypertens. 2015 Jun ;33 Suppl 1:e80.IF: 4,72 11. Mansego ML, De Marco G, Ivorra C, López-Izquierdo R, Morcillo S, Rojo-Martínez G, González-Albert V, Martínez F, Soriguer F, Martín-Escudero JC, Redon J, Chaves FJ. The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study.J Transl Med. 2015 Sep 2 ;13:286.IF: 3,93 12. Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin- García P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM. Obesity changes the human gut mycobiome.Sci Rep. 2015 Oct 12 ;5:14600.IF: 5,578 13. Perez-Hernandez J, Forner MJ, Pinto C, Chaves FJ, Cortes R, Redon J. Increased Urinary Exosomal MicroRNAs in Patients with Systemic Lupus Erythematosus.PLoS One. 2015 ;10(9):e0138618.IF: 3,234 14. Mora M, Adam V, Palomera E, Blesa S, Díaz G, Buquet X, Serra-Prat M, Martín-Escudero JC, Palanca A, Chaves JF, Puig-Domingo M, Mataró Aging Study Group. Ghrelin Gene Variants Influence on Metabolic Syndrome Components in Aged Spanish Population.PLoS One. 2015 ;10(9):e0136931. IF: 3,234 Review 15. Perez-Hernandez J, Cortes R. Extracellular Vesicles as Biomarkers of Systemic Lupus Erythematosus.Dis Markers. 2015 ;2015:613536.IF: 1,562 • RESEARCH PROJECTS AND GRANTS FOR RESEARCH Reference: PI12/02615 Title: Podocitos y sus componentes como biomarcadores de lesión en hipertensión arterial, diabetes y obesidad Principal Investigator: Josep Redón i Mas (Pablo Marin, Raquel Cortés, Verónica González and Pilar Rentero as collaborating researchers) Funding Body: Instituto de Salud Carlos III Beneficiary Institution: Fundación Investigación Hospital Clínico Universitario Valencia Duration: 2013-2016 Total budget: 329.120€ Reference: PI12/01978 Title: Association of insulin resistance and oral fat load test with DNA methylation of adipocytes and hepatocytes in subjects with morbid obesity Principal Investigator: José Tomás Real Collado (Verónica González and Victoria Adam as collaborating researchers) Funding Body: Instituto de Salud Carlos III Beneficiary Institution: Fundación Investigación Hospital Clínico Universitario de Valencia Duration: 2013-2015 Total budget: 121.000€ Reference: PI14/00874 Title: Identification of exome sequence changes, methylation and hydroxymethylation associated in the development of type 2 diabetes principal. Principal Investigator: Felipe Javier Chaves Martínez Funding Body: Instituto de Salud Carlos III Beneficiary Institution: Fundación Investigación Hospital Clínico Universitario de Valencia Duration: 2015-2017 Total budget: 162.000€ • THESIS Thesis title: Identificación de variantes exómicas en diabetes tipo 2 Doctoral candidate: Vanessa Martínez Barquero Director(s): Juan F. Ascaso Gimilio, Mª Antonia Noguera Romero, Felipe Javier Chaves Martínez Date of the defense: 05/06/2015 Grade: Sobresaliente “cum laude”
Scientific activity 4 Thesis title: Identificación de los perfiles de expresión en el adenocarcinoma ductal de páncreas. Implicaciones clínicas. Doctoral candidate: María Del Carmen Gómez Mateo Director(s): Felipe Javier Chaves Martínez, Antonio Ferrández Izquierdo, Luis Sabater Ortí Date of the defense: 08/07/2015 Grade: Sobresaliente “cum laude” 49
Page 1 and 2: SCIENTIFIC REPORT 2015
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Initiatives for research promotion
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Highlights 7
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Higlights 7 JULY INCLIVA and Lanzad
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8 INCLIVA Solidary PROYECTO MAMA IN
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8 INCLIVA Solidary nia Torre, Cesar
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Avda. Menéndez Pelayo, 4 accesorio
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