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Pharmaceutical manufacturing contributes significantly to Ireland’s<br />

economy. The industry employs over 25,000 individuals directly<br />

and 24,500 indirectly, and produces over 50% of all exports,<br />

making Ireland the second-largest pharmaceutical exporter in<br />

the world. Each pharmaceutical drug produced for the market<br />

is the culmination of at least a decade of sustained science<br />

and engineering research that transforms a molecule into a<br />

pharmaceutical material and, ultimately, into a medicine for the<br />

benefit of patients, society and the wider economy. Next generation<br />

drug manufacture will require a more integrated approach to<br />

manufacturing pharmaceuticals, aimed at reducing the time and cost<br />

to market and meeting the ever increasing regulatory requirements.<br />

Launched in July 2013, the <strong>SSPC</strong> research programme leads the way for next generation<br />

drug manufacture. The <strong>SSPC</strong> is the largest research collaboration in Ireland, and one of the<br />

largest globally, within the pharmaceutical area. The <strong>SSPC</strong> represents a significant combined<br />

Science Foundation Ireland and industry investment of €42 million. The <strong>SSPC</strong> builds upon the<br />

success and foundations of the Solid State Pharmaceutical Cluster (2007-2013), which was<br />

funded by Science Foundation Ireland’s Strategic Research Cluster programme. The Solid<br />

State Pharmaceutical Cluster research programme focused exclusively upon the crystallisation<br />

stage of the manufacturing process. Within the pharmaceutical industry, this stage is the<br />

most challenging aspect of manufacturing, as there is a significant lack of fundamental<br />

understanding of the science and engineering challenges at this stage of the process.<br />

Building upon this success, the <strong>SSPC</strong> research programme now spans the entire<br />

pharmaceutical production chain from synthesis of the molecule, to the isolation of the<br />

material, to the formulation of the medicine. <strong>SSPC</strong> research focuses upon developing more<br />

environmentally sustainable methods for drug manufacturing; increasing the range of<br />

medicines available to the public; and reducing drug manufacturing costs. The <strong>SSPC</strong> aims<br />

to deliver industry relevant solutions, which result in job growth and retention within the<br />

pharmaceutical industry in Ireland.<br />

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