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2007GuideToTheFirstYear

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catch them early, it seems clear that we should<br />

monitor co-MZ twins when one twin has a<br />

significant medical problem. The chances that<br />

this will happen in DZ twins is much less,<br />

because these twins only share about half of<br />

their genes in common.<br />

There are dramatic examples where MZ<br />

twins have been excellent transplant donors<br />

and recipients, with no possibility that the<br />

transplanted organ will be rejected. There is<br />

no need to use anti-rejection chemotherapy<br />

when organs are donated between MZ twins.<br />

DZ twins might make quite good matches,<br />

but anti-rejection therapy will always be<br />

required.<br />

Some of these points may seem a bit grim<br />

and serious, but they are within the experience<br />

of every professional who helps twins deal with<br />

their lives and their biology. Fortunately, most<br />

twins never encounter these problems. But if I<br />

were a parent of twins, I would definitely want<br />

to know my children's zygosity.<br />

Geoffrey Machin, M.D., Ph.D., internationally<br />

recognized fetal pathologist, has helped twins<br />

and their parents with questions of zygosity for<br />

more than 10 years. He has known more than<br />

300 twin pairs who thought they were DZ learn<br />

they were MZ after a DNA test.<br />

Identical or Fraternal?<br />

The Twin DNA Test<br />

Easy, at-home testing.<br />

99+% accuracy.<br />

Results in 7-10 business days.<br />

Affordable.<br />

order online:<br />

www.proactivegenetics.com<br />

© 2007 TWINS Magazine. To subscribe: call 1-888-55-TWINS or www.TwinsMagazine.com GUIDE TO THE FIRST YEAR 33

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