Hola MaHigh-School - August 2018
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Gene editing<br />
indistinguishable from naturally occurring mutations.”<br />
In short: the new technique Crispr-Cas9 gives us the opportunity<br />
to identify a piece of the DNA we wish to alter, cut it out and provide<br />
a new strand which might have been created by the scientist.<br />
It is not necessarily something which nature designed. We design<br />
it!<br />
Let us rewind a bit on this:<br />
We need to invent a ‘scissor’ that will recognise a specific sequence.<br />
What if this sequence is also found somewhere else in the<br />
strand of DNA, not where we want to cut? So we can cut something<br />
else and we might never know? Until we see the result? The<br />
organism does not do what we intended it to do. Because we cut<br />
the wrong piece! And what we inserted does not make sense at<br />
that place in the DNA.<br />
Now what? Exactly!<br />
We now insert a designer piece of DNA. Do we really know what<br />
it will code for? So we ‘edit’ a piece of DNA and insert it in a living<br />
organism and now we can see the change. Crop yields or immune<br />
to cancer. But if we get it a bit wrong? Exactly!