Chemistry and Chemical Physics Graduate Programs brochure
Chemistry and Chemical Physics Graduate Programs brochure
Chemistry and Chemical Physics Graduate Programs brochure
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University of Nevada, Reno<br />
<strong>Chemistry</strong><br />
AND CHEMICAL PHYSICS<br />
GRADUATE STUDIES
Contents<br />
Welcome 3<br />
About the University of Nevada, Reno 4<br />
The <strong>Chemistry</strong> Program 5<br />
Degree <strong>Programs</strong> 5<br />
Courses 5<br />
Credit Requirements 5<br />
Examinations 6<br />
Student Seminars 6<br />
Research 6<br />
<strong>Graduate</strong> Teaching 7<br />
<strong>Graduate</strong> Courses 7<br />
<strong>Graduate</strong> Admission 8<br />
<strong>Chemical</strong> <strong>Physics</strong> Program 9<br />
Facilities <strong>and</strong> Equipment 11<br />
Reno: The Community <strong>and</strong> Its Setting 13<br />
The Faculty<br />
Above: Students align a Nd:YAG laser system in Dr.<br />
Cline’s laboratory. Below: Reno skyline. At right:<br />
the <strong>Chemistry</strong> building. On cover: View of the<br />
University of Nevada.<br />
Frank G. Baglin 16<br />
Thomas W. Bell 17<br />
Ana de Bettencourt-Dias 18<br />
Sean M. Casey 19<br />
Vincent J. Catalano 20<br />
Joseph I. Cline 21<br />
Kent M. Ervin 22<br />
Brian J. Frost 23<br />
Benjamin T. King 24<br />
David M. Leitner 25<br />
David A. Lightner 26<br />
Jason Shearer 27<br />
Robert S. Sheridan 28<br />
Suk-Wah Tam-Chang 29<br />
Hyung-June Woo 30<br />
Liming Zhang 31<br />
Sarah A. Cummings, Garry N. Fickes, Sési M. McCullough, Charles B. Rose 32<br />
Scott W. Waite, Richard D. Burkhart 33<br />
Kenneth C. Kemp, H. Eugene Lemay, Jr., John H. Nelson 34<br />
Hyung K. Shin 35
Thank you for your interest in the Department of <strong>Chemistry</strong> at the<br />
University of Nevada, Reno.<br />
We are a teaching- <strong>and</strong> research-oriented department offering degrees<br />
in <strong>Chemistry</strong> (B.S., M.S., Ph.D.), Environmental <strong>Chemistry</strong> (B.S.), <strong>and</strong><br />
<strong>Chemical</strong> <strong>Physics</strong> (Ph.D., jointly with the <strong>Physics</strong> Department), including<br />
bachelor’s degree programs certified by the American <strong>Chemical</strong> Society.<br />
As a relatively small department, we are able to provide close interactions<br />
among students <strong>and</strong> faculty. Many of our undergraduates <strong>and</strong> all of<br />
our graduate students participate in state-of-the-art chemistry research,<br />
working with a faculty mentor. Our graduates go on to employment in<br />
academia, industry, <strong>and</strong> government; many of our Bachelor’s degree graduates are admitted<br />
to high-ranked graduate chemistry programs, medical, or dental schools. In the most recent<br />
National Resource Council survey of chemistry departments, our department was ranked<br />
second nationally among departments of our size or smaller.<br />
We are located in the <strong>Chemistry</strong> Building near the<br />
center of the University of Nevada, Reno campus.<br />
This <strong>brochure</strong> is designed to provide information for<br />
both current <strong>and</strong> prospective students about our<br />
programs <strong>and</strong> services. More detail can be found on<br />
our web site (link at right).<br />
Please contact us if you have any questions.<br />
— Dr. Vince Catalano, Department Chair<br />
3<br />
For more information write:<br />
<strong>Graduate</strong> Admissions Committee<br />
Department of <strong>Chemistry</strong><br />
University of Nevada, Reno<br />
Reno, NV 89557-0216<br />
E-mail: grad@chem.unr.edu<br />
Website: www.chem.unr.edu<br />
Or call (775)-784-6041
About the University of Nevada, Reno<br />
Situated on the foothills at the northern edge of the<br />
Truckee Meadows metropolitan area, the University of<br />
Nevada campus comm<strong>and</strong>s a panoramic view of the<br />
Washoe Mountains to the east, the Sierra Nevada to the<br />
west, <strong>and</strong> Reno to the south. The University is a l<strong>and</strong><br />
grant institution <strong>and</strong> the oldest of the eight institutions<br />
in the Nevada System of Higher Education. The student<br />
body numbers over 16,000 <strong>and</strong> consists of the Colleges<br />
of Agriculture, Biotechnology, <strong>and</strong> Natural Resources;<br />
Business Administration; Education; Engineering; Health<br />
<strong>and</strong> Human Sciences; the Reynolds School of Journalism;<br />
Liberal Arts; Medicine; <strong>and</strong> Science. Additionally,<br />
Cooperative Extension is a non-degree-granting college.<br />
Several schools exist as sub-units of the colleges, including<br />
the Schools of Nursing, Public Health, <strong>and</strong> Social Work<br />
in Health <strong>and</strong> Human Sciences, the School of the Arts in Liberal Arts, <strong>and</strong> the Mackay School of<br />
Earth Sciences <strong>and</strong> Engineering in the College of Science. The Department of <strong>Chemistry</strong> is part<br />
of the College of Science with its graduate programs administered by the <strong>Graduate</strong> School.<br />
The 255-acre main campus features both historic <strong>and</strong> contemporary<br />
architecture. The central campus includes scenic Manzanita<br />
Lake (pictured above) <strong>and</strong> the beautiful elm-lined Quadrangle<br />
(pictured at left), listed on the National Register of Historic Places.<br />
On the campus are five galleries <strong>and</strong> museums, the Church Fine<br />
Arts Complex with several theaters, <strong>and</strong> the Lawlor Events Center, a<br />
regular site for concerts, athletic events, <strong>and</strong> other local activities. At<br />
the north end of campus are the university-affiliated Fleischmann<br />
Planetarium <strong>and</strong> the E.L. Cord Public Telecommunications Center,<br />
The central Quad on the<br />
campus.<br />
which provide educational programs <strong>and</strong> public radio/TV broadcasting.<br />
Although affordable on-campus parking is available for students,<br />
many choose to find housing among a wide variety available<br />
within convenient walking or cycling distance to campus. There is also an extensive public<br />
transportation system providing campus access from throughout the Truckee Meadows.<br />
The University is the cultural focus of Northern Nevada, sponsoring a special performing<br />
artist series, a plethora of musical concerts, an active drama program with several plays on<br />
campus each year, <strong>and</strong> frequent exhibitions that feature local artists. In addition, it supports<br />
major college athletics such as football, basketball, track, baseball, swimming, <strong>and</strong> volleyball as<br />
a member of the Western Athletic Conference (WAC).<br />
The chemistry department maintains a close relationship with other campus departments<br />
with related interests, including biochemistry, molecular biology, <strong>and</strong> physics. The Desert<br />
Research Institute (DRI), a division of the university system, is headquartered in Reno <strong>and</strong><br />
sponsors research programs of particular concern to Nevada <strong>and</strong> other western states. Desert<br />
biology, atmospheric chemistry <strong>and</strong> physics, <strong>and</strong> water <strong>and</strong> soil resources are primary areas of<br />
research at the institute.<br />
4<br />
Manzanita Lake on the University<br />
campus.
The <strong>Chemistry</strong> Program<br />
In comparison with many contemporary graduate institutions, Nevada’s chemistry department<br />
enjoys an exceedingly favorable student to faculty ratio, with 17 faculty, 60-65 graduate<br />
students, <strong>and</strong> typically 12-15 postdoctoral associates <strong>and</strong> visiting faculty. Our department has<br />
enjoyed tremendous growth in its personnel <strong>and</strong> research facilities over the past 10 years. The<br />
research programs in the department enjoy an excellent international reputation, reflecting our<br />
commitment to quality <strong>and</strong> our success in competing for research funding. Research grants in<br />
the department total more than $1 million per year, with much of that money spent on support<br />
for graduate research assistants.<br />
An important aspect of graduate education is exposure to <strong>and</strong> interaction with scientists<br />
from outside the university. The department maintains an outst<strong>and</strong>ing seminar program<br />
with approximately 40 outside speakers of international stature each year, many from overseas.<br />
Among the highlights of this program are the annual R.C. Fuson Lectureship, the annual<br />
Distinguished Physical Chemist Lectureship, <strong>and</strong> the biennial Sierra Nevada ACS Distinguished<br />
Chemist Lectureship, which have featured many Nobel Laureates.<br />
Degree <strong>Programs</strong>: The Department of <strong>Chemistry</strong> offers<br />
graduate programs leading to a Master of Science in<br />
<strong>Chemistry</strong> <strong>and</strong> to a Doctor of Philosophy in <strong>Chemistry</strong>. An<br />
interdisciplinary Ph.D. program in <strong>Chemical</strong> <strong>Physics</strong> is offered<br />
in cooperation with the Department of <strong>Physics</strong>. Students<br />
enrolled in the <strong>Chemical</strong> <strong>Physics</strong> program follow a different<br />
set of requirements, outlined beginning on page 9.<br />
Courses: The department emphasizes individualized<br />
programs for each graduate student, tailored to interest <strong>and</strong><br />
career goals. Initial assessment examinations in inorganic,<br />
organic, <strong>and</strong> physical chemistry are given at the beginning<br />
of students’ graduate studies in order to ascertain preparation<br />
levels. The examinations are used primarily for initial<br />
Students discuss organic chemistry<br />
in Dr. Zhang’s laboratory.<br />
advisement purposes to help select a program of courses appropriate to individual student<br />
training. Each year a monetary award is presented to the entering student with the best overall<br />
performance on these exams.<br />
<strong>Chemistry</strong> M.S. <strong>and</strong> Ph.D. graduates are expected to have a broad background in the major<br />
areas of chemistry. Most students take “core” courses in the areas of inorganic (CHEM 631),<br />
organic (CHEM 642), <strong>and</strong> physical chemistry (CHEM 650) during their first semester. Students<br />
that demonstrate exceptional proficiency in one or more areas on the qualifying exams may be<br />
exempted from taking the corresponding core courses. Following the graduate core courses,<br />
two additional graduate lecture courses are required for the M.S. degree; four additional graduate<br />
lecture courses are required for the Ph.D. degree. These specialized courses are chosen<br />
in consultation with one’s research adviser to fit specific interests <strong>and</strong> to provide a suitable<br />
background for research.<br />
Credit Requirements: The general credit requirements for the M.S. <strong>and</strong> Ph.D. degrees in<br />
<strong>Chemistry</strong> are listed on the website at: www.chem.unr.edu. Information on requirements for<br />
5
the <strong>Chemical</strong> <strong>Physics</strong> Ph.D. program are given separately on pages 9-10. Further details about<br />
degree requirements, including general requirements of the <strong>Graduate</strong> School, may be found in<br />
the most recent General Catalog of the University of Nevada, Reno, <strong>and</strong> the <strong>Chemistry</strong> <strong>Graduate</strong><br />
Student Guidelines, which always supersede the information given here.<br />
Examinations: The written c<strong>and</strong>idacy exam in chemistry is a series of cumulative examinations<br />
that are given to test one’s ability to solve problems in chemistry <strong>and</strong> to integrate material<br />
from various courses, the current chemical literature, <strong>and</strong> seminars. After completion of the<br />
cumulative exam requirement an oral comprehensive examination is required for admission to<br />
Ph.D. c<strong>and</strong>idacy. Fulfillment of the requirements for the M.S. <strong>and</strong> Ph.D. degrees is attained with<br />
the writing of an original thesis (M.S.) or dissertation (Ph.D.) on one’s research. Finally, the thesis<br />
or dissertation is defended in an oral examination before one’s graduate advisory committee.<br />
Student Seminars: Recognizing the importance of oral communication in the sciences, the<br />
department requires all graduate students to present at least two departmental seminars. The<br />
first of these is given in the third semester of residence <strong>and</strong> is based on a topic taken from the<br />
chemical literature. The second seminar, usually given no later<br />
than the third year of residence, is a final thesis seminar for M.S.<br />
c<strong>and</strong>idates <strong>and</strong> a “research progress report” for Ph.D. c<strong>and</strong>idates.<br />
Ph.D. students also often present a dissertation seminar immediately<br />
prior to their oral defense.<br />
Students work on an ultrahigh<br />
vacuum chamber in Dr. Casey’s<br />
laboratory.<br />
Research: Research is the foundation for all the graduate<br />
degree programs offered by the Department of <strong>Chemistry</strong>. The<br />
focus of graduate study is a program of original research under<br />
the direction of a faculty adviser. Students are encouraged to<br />
select a research adviser <strong>and</strong> start on thesis (M.S.) or dissertation<br />
(Ph.D.) research by the second semester in residence. This<br />
is especially important as one’s research topic is a large factor in<br />
determining subsequent course curriculum. Research study options in the department include<br />
organic chemistry, inorganic chemistry, physical chemistry, theoretical chemistry, chemical<br />
physics, physical organic chemistry, bio-organic chemistry,<br />
bio-inorganic chemistry, <strong>and</strong> organometallic chemistry. After<br />
choosing a research adviser, a graduate advisory committee<br />
comprised of the adviser <strong>and</strong> other faculty in the chemistry<br />
department is formed. This committee approves programs of<br />
study <strong>and</strong> presides over oral examinations. The research program<br />
culminates in the completion of a thesis or dissertation.<br />
<strong>Graduate</strong> Teaching: The ability to communicate knowledge<br />
to others is an important part of a graduate education,<br />
whether or not one plans to pursue a career in teaching. The<br />
department requires that all graduate students have some<br />
teaching experience as part of their advanced degree require-<br />
6<br />
A student working up a reaction<br />
in Dr. Bell’s laboratory.
ments. To aid in the development of teaching <strong>and</strong> communication skills, beginning teaching<br />
assistants participate in the <strong>Graduate</strong> School Instructional Development orientation program<br />
just prior to their first fall semester, <strong>and</strong> take CHEM 700, Supervised Teaching in College <strong>Chemistry</strong>,<br />
during their first fall semester.<br />
A typical first year graduate student is assigned to teach two laboratories per week (6 contact<br />
hours) plus some exam proctoring <strong>and</strong> grading. Lab responsibilities include providing brief<br />
introductions of the experiments, answering student questions in lab, <strong>and</strong> grading students’<br />
written lab reports. Experiments take 1.5 to 3 hours <strong>and</strong> the enrollment of lab sections is<br />
limited to 25 students. Teaching assistants frequently generate <strong>and</strong> administer pre lab quizzes<br />
to their students to test preparation <strong>and</strong> underst<strong>and</strong>ing of concepts used in the experiments.<br />
Each year the department presents an award to its outst<strong>and</strong>ing teaching assistant.<br />
<strong>Graduate</strong> Courses: The following is a listing of regularly offered graduate courses in the<br />
Department of <strong>Chemistry</strong>. Courses in other departments of interest to chemistry graduate<br />
students may be found in the UNR General Catalog. The University of Nevada, Reno operates<br />
on the semester system with the Fall semester beginning in late August <strong>and</strong> ending in mid<br />
December, <strong>and</strong> the Spring semester beginning in late January <strong>and</strong> ending in mid May.<br />
631 ADVANCED INORGANIC CHEMISTRY<br />
635 CHEMICAL SYNTHESIS<br />
642 ADVANCED ORGANIC CHEMISTRY<br />
643 ORGANIC SPECTROSCOPY AND STRUCTURE<br />
644 ORGANIC STRUCTURE DETERMINATION LABORATORY<br />
649 POLYMER CHEMISTRY<br />
650 ADVANCED PHYSICAL CHEMISTRY<br />
651 THE ELEMENTARY PHYSICAL CHEMISTRY OF MACROMOLECULES<br />
655 INSTRUMENTAL ANALYSIS<br />
700 SUPERVISED TEACHING IN COLLEGE CHEMISTRY<br />
711 THEORETICAL INORGANIC CHEMISTRY<br />
712 THE LESS FAMILIAR ELEMENTS<br />
713 ORGANOMETALLIC CHEMISTRY<br />
714 SPECIAL TOPICS IN INORGANIC CHEMISTRY<br />
740 ADVANCED ORGANIC SYNTHESIS<br />
741 ADVANCED ORGANIC STRUCTURE ELUCIDATION<br />
742 THEORETICAL ORGANIC CHEMISTRY<br />
743 SPECIAL TOPICS IN ORGANIC CHEMISTRY<br />
744 STEREOCHEMISTRY AND CONFORMATIONAL ANALYSIS<br />
745 CHEMISTRY OF NATURAL PRODUCTS<br />
751 SPECIAL TOPICS IN PHYSICAL CHEMISTRY<br />
752 CHEMICAL KINETICS<br />
754 MOLECULAR SPECTROSCOPY<br />
755 STATISTICAL THERMODYNAMICS<br />
757 QUANTUM CHEMISTRY<br />
7
<strong>Graduate</strong> Admission: Formal application is required for admission to the degree programs of<br />
the <strong>Graduate</strong> School. Application materials may be requested by writing to the address given<br />
below or visiting the web site at www.chem.unr.edu. The application consists of several parts,<br />
including an application form for admission to our graduate school <strong>and</strong> an application form for<br />
graduate fellowship for financial support, instructions for completing these forms, <strong>and</strong> envelopes<br />
for letters of recommendation written by individuals able to comment on one’s qualifications<br />
for graduate studies. Completed application forms should then be sent directly to the<br />
chemistry department. The department accepts applications at all times of the year; however,<br />
most students apply during the winter <strong>and</strong> spring of their senior year in college for admission<br />
in the following fall semester.<br />
Applicants should have a bachelor’s degree in chemistry or a related field, <strong>and</strong> should have<br />
a minimum GPA of 3.0 on a 4.0 scale for admission to the Ph.D. program <strong>and</strong> 2.75 (or 3.0 for the<br />
last two years) for the M.S. program. <strong>Graduate</strong> Record Examination (GRE) general exam scores<br />
must be submitted as part of the application. Consideration for admission to the department’s<br />
program is based on one’s apparent potential for successful completion of the degree<br />
as indicated by undergraduate performance, letters of recommendation, <strong>and</strong> GRE scores. The<br />
department encourages applications from women <strong>and</strong> minority students.<br />
Financial Aid: Financial support for incoming graduate students is provided primarily through<br />
teaching fellowships. The amount of the stipend for a ten month appointment is adjusted for<br />
cost of living increases each year, <strong>and</strong> the department should be contacted to learn the current<br />
stipend. Students generally receive an additional two month research fellowship during<br />
the summer. It should be noted that the actual value of a teaching fellowship appointment<br />
for an out of state student is quite a bit higher because tuition <strong>and</strong> other fees are significantly<br />
subsidized.<br />
Financial support from research assistantships <strong>and</strong> fellowships is also available to highly<br />
qualified entering students. It is the usual practice of the department to support students<br />
during the entire time that they are working toward an advanced degree. Most students<br />
are supported during the bulk of their graduate studies on their research director’s research<br />
grants. It has been our experience that the stipends we provide to students, coupled with the<br />
reasonable cost of living found in Reno, make it possible for students to maintain a comfortable<br />
lifestyle.<br />
For more information regarding the department’s graduate<br />
program <strong>and</strong> financial assistance, please contact:<br />
Chairman, <strong>Graduate</strong> Admissions Committee<br />
Department of <strong>Chemistry</strong><br />
University of Nevada, Reno<br />
1664 N. Virginia St.<br />
Reno, NV 89557-0216<br />
E-mail: grad@chem.unr.edu<br />
or to apply on-line please see our web site at:<br />
http://www.chem.unr.edu<br />
8<br />
Students load a sample into an<br />
ultrahigh vacuum chamber for surface<br />
chemical analysis in Dr. Casey’s<br />
laboratory.
<strong>Chemical</strong> <strong>Physics</strong><br />
The chemical physics program provides an interdisciplinary curriculum for those students<br />
whose primary research interests are in atomic <strong>and</strong> molecular physics <strong>and</strong> physical chemistry.<br />
While requiring the student to complete a rigorous selection of courses that outline the foundations<br />
of modern chemical physics, the chemical physics program also offers extreme flexibility<br />
in the choice of dissertation topic as the student may choose any of the affiliated faculty<br />
in either the chemistry or the physics departments to serve as a research adviser.<br />
<strong>Graduate</strong>s of the program have gone on to a variety of outst<strong>and</strong>ing postdoctoral research<br />
<strong>and</strong> teaching positions, with many excellent employment opportunities awaiting them in<br />
academics, industry, <strong>and</strong> government research labs. Several of today’s most exciting new technologies<br />
are in the areas of molecular <strong>and</strong> materials sciences— for example, nanotechnology,<br />
molecular devices, <strong>and</strong> high temperature superconducting materials— <strong>and</strong> a background in<br />
chemical physics is the key to exploring the future in these areas.<br />
Curriculum: The curriculum in chemical physics is based on five required, or “core,” courses<br />
which should be taken as early as possible in the student’s residency. The core courses are<br />
comprised of the following:<br />
Mathematical <strong>Physics</strong> PHYS 701<br />
Quantum Theory I CHEM 757 or PHYS 721<br />
Quantum Theory II PHYS 722 or CHEM 750<br />
Statistical Mechanics CHEM 755 or PHYS 732<br />
Choice of:<br />
Classical Mechanics PHYS 702<br />
<strong>Chemical</strong> Kinetics CHEM 752<br />
Modern Optics <strong>and</strong> Laser <strong>Physics</strong> PHYS 730<br />
Additional, or “elective,” courses in areas of particular interest to the student are then used to<br />
fill out the curriculum. These courses are typically chosen from the 600- <strong>and</strong> 700-level courses<br />
offered by the physics, chemistry, <strong>and</strong> mathematics departments. A full listing of the degree<br />
requirements for the program can be found on the web page: www.chemphys.unr.edu<br />
Associated Faculty: The faculty associated with the chemical physics program are listed<br />
below along with a brief indication of their research areas.<br />
Frank G. Baglin <strong>Chemistry</strong> Raman scattering in supercritical fluids<br />
Bruno S. Bauer <strong>Physics</strong> Experimental studies of plasma waves <strong>and</strong><br />
instabilities<br />
Reinhard Bruch <strong>Physics</strong> Low <strong>and</strong> high energy ion-atom <strong>and</strong> ion-<br />
molecule collisions<br />
Sean M. Casey <strong>Chemistry</strong> Semiconductor surface science<br />
Joseph I. Cline <strong>Chemistry</strong> Molecular stereodynamics<br />
Andrei Derevianko <strong>Physics</strong> Theoretical physics<br />
9
Kent M. Ervin <strong>Chemistry</strong> Cluster ion reactions <strong>and</strong> photophysics<br />
David M. Leitner <strong>Chemistry</strong> Biophysical theoretical chemistry<br />
Roberto C. Mancini <strong>Physics</strong> Theory <strong>and</strong> modeling of laser-produced<br />
transient plasmas<br />
Katherine R. McCall <strong>Physics</strong> Theoretical condensed matter physics<br />
Hans Moosmüller <strong>Physics</strong> Atmospheric <strong>and</strong> aerosol physics<br />
Ronald A. Phaneuf <strong>Physics</strong> Experimental studies of highly charged ion<br />
interactions with electrons <strong>and</strong> atoms<br />
Alla Safranova <strong>Physics</strong> Theoretical plasma physics<br />
Jonathan Weinstein <strong>Physics</strong> Ultracold atomic <strong>and</strong> molecular physics<br />
Peter Winkler <strong>Physics</strong> Theory of many-body systems<br />
Hyung-June Woo <strong>Chemistry</strong> Biophysical theoretical chemistry<br />
Admission: Admission into the chemical physics program is h<strong>and</strong>led separately by the chemistry<br />
<strong>and</strong> physics departments. Interested students whose background is primarily in chemistry<br />
are encouraged to apply through the chemistry department, listing “chemical physics” as the<br />
specific area of chemistry on the application form. Those students whose background is in<br />
physics should likewise seek admission through the physics department. The individual departments<br />
provide financial support through teaching <strong>and</strong> research fellowships to the chemical<br />
physics students that they admit.<br />
For more information about the program, please contact:<br />
Prof. Joseph I. Cline<br />
Director, <strong>Chemical</strong> <strong>Physics</strong> Program<br />
Department of <strong>Chemistry</strong><br />
University of Nevada, Reno<br />
1664 N. Virginia St.<br />
Reno, NV 89557-0216<br />
WWW: http://www.chemphys.unr.edu<br />
10
Facilities <strong>and</strong> Equipment<br />
<strong>Chemistry</strong> research is heavily reliant on modern facilities, instrumentation, <strong>and</strong> technical<br />
support personnel. The <strong>Chemistry</strong> Department at Nevada is endowed with a full complement<br />
of support services, shops, <strong>and</strong> laboratories. These facilities are managed by our Director of<br />
<strong>Chemistry</strong> Laboratories, Scott Waite.<br />
The <strong>Chemistry</strong> Building is a four-story structure located in the central campus, adjoining the<br />
Leifson <strong>Physics</strong> Building <strong>and</strong> near the engineering research complex. Custom research instruments<br />
are fabricated in our professionally staffed machine shop<br />
<strong>and</strong> a student shop is also available. Specialty glassware <strong>and</strong><br />
high vacuum systems are fabricated in the glass shop. Custom<br />
circuit design, construction, <strong>and</strong> instrument maintenance is<br />
provided by electronics engineer Tom Grothaus in the electronics<br />
shop.<br />
Research in synthetic chemistry is heavily dependent on the<br />
most sophisticated tools for structure elucidation. The Magnetic<br />
A student sets up a reaction<br />
in a fume hood in Dr. Bell’s<br />
laboratory.<br />
Resonance Laboratory houses three nuclear magnetic resonance<br />
spectrometers for departmental use: two Varian 400-MHz spectrometers,<br />
<strong>and</strong> a Varian Unity-Plus 500-MHz spectrometer. The<br />
400-MHz instruments are equipped with quad nucleus probes<br />
(proton, fluorine, carbon, <strong>and</strong> phosphorous) <strong>and</strong> a 100 sample autochanger. The Varian-500 is<br />
a multi-nuclear instrument with variable temperature, double resonance, <strong>and</strong> two-dimensional<br />
capabilities, <strong>and</strong> it can also carry out C/H/P triple resonance, indirect detection, <strong>and</strong> gradient<br />
spectroscopy. Each NMR instrument is connected by Ethernet to remote data stations for<br />
off-line data processing <strong>and</strong> analysis. Magnetic resonance specialist Lew Cary maintains these<br />
instruments <strong>and</strong> provides expert assistance with more sophisticated experiments. The X-ray<br />
structure determination laboratory is equipped with a Bruker-Nonius SMART Apex CCD-based<br />
single crystal diffractometer with low temperature capabilities. This instrument is interfaced to<br />
multiple workstations for data analysis <strong>and</strong> structure visualization. Mass spectrometry can be<br />
performed using a Saturn GC-MS equipped with an autoinjector, a Bruker Proflex MALDI-TOF<br />
instrument, a Waters atmospheric pressure chemical ionization / photoionization / electrospray<br />
ionization (APCI / APPI / ESI) quadrupole mass spectrometer, or the high-resolution mass spectrometry<br />
center on campus, depending on one’s sample needs. Transient emission, absorption,<br />
<strong>and</strong> excited state lifetime studies are possible using the departmental laser spectroscopy facility<br />
which includes a diode array spectrometer <strong>and</strong> a tunable pulsed laser. The department also<br />
maintains an atomic absorption spectrometer, a routine Perkin-Elmer Spectrum 2000 FTIR with<br />
mid- <strong>and</strong> far-IR capabilities, a routine Fluoromax-3 Horiba fluorimeter, several UV-vis spectrophotometers,<br />
<strong>and</strong> a scanning tunneling microscope that are primarily used for instructional<br />
purposes. Electronic absorption, infra-red, <strong>and</strong> fluorescence spectroscopies are facilitated by<br />
several other departmental teaching spectrometers.<br />
Computational facilities are a critically important part of chemical research. The chemistry<br />
department maintains several high performance Beowulf computer clusters. The departmental<br />
general use cluster is configured with 42 2.2-GHz AMD Opteron (64-bit) processors, 84 GB of<br />
RAM, TB RAID disk storage, <strong>and</strong> gigabit networking. Computational research groups also have<br />
their own clusters. PBS <strong>and</strong> a sophisticated scheduler h<strong>and</strong>le job allocations. Available applica-<br />
11
tions include Gaussian 03,<br />
Amber, NWChem, Ghemical,<br />
<strong>and</strong> ORCA. A chemistry computing<br />
laboratory consisting of<br />
12 Pentium IV-class computers<br />
is available for instructional<br />
<strong>and</strong> research computing.<br />
These departmental machines,<br />
together with those in<br />
individual research groups, are<br />
connected by the departmental<br />
Ethernet to the high-speed<br />
campus fiber optic computing<br />
backbone <strong>and</strong> the Internet.<br />
The department’s computer<br />
systems are coordinated by<br />
our Computing <strong>and</strong> Networking<br />
Administrator.<br />
Much of our most impressive<br />
<strong>and</strong> specialized instrumentation<br />
is found within the<br />
laboratories of individual research<br />
groups. Computational<br />
equipment available includes<br />
UNIX <strong>and</strong> LINUX workstations <strong>and</strong> a host of<br />
desktop microcomputers. The physical chemistry<br />
groups utilize lasers for non-linear, highresolution,<br />
or fast spectroscopy, <strong>and</strong> for studies<br />
of molecular dynamics. Laser equipment<br />
includes pulsed high-power Nd:YAG lasers, tunable<br />
infrared <strong>and</strong> visible semiconductor lasers,<br />
high-power excimer lasers, Ar ion lasers, copper<br />
vapor lasers, <strong>and</strong> several tunable CW <strong>and</strong><br />
pulsed dye lasers. Other state-of-the-art equipment<br />
includes high vacuum molecular beam<br />
<strong>and</strong> ion beam chambers, ultra-high vacuum<br />
chambers for studies of surface chemistry, a<br />
variety of specialized optics <strong>and</strong> instruments<br />
for nonlinear spectroscopy <strong>and</strong> polarized laser<br />
experiments, ion <strong>and</strong> photon detectors, fast<br />
digital oscilloscopes <strong>and</strong> detection electronics,<br />
<strong>and</strong> time-of-flight, quadrupole, <strong>and</strong> magnetic<br />
mass spectrometers <strong>and</strong> octopole ion traps.<br />
Most synthetic chemistry groups have their<br />
Chemsitry front office staff: (l to r) Roxie Taft, Jennifer Melius,<br />
Xanthea Elsbree, <strong>and</strong> Jenny Costa.<br />
12<br />
(Above left) Machinist Walt Weaver fabricates<br />
specialized instruments for research projects in<br />
the chemistry department. (Above) Electrical<br />
engineer Tom Grothaus designs <strong>and</strong> fabricates<br />
custom electronic circuits for research projects.<br />
(Above right) Lew Cary manages the departmental<br />
magnetic resonance laboratories.
own Fourier transform IR spectrometers <strong>and</strong> other specialized research instruments.<br />
The DeLaMare Library currently subscribes to about 1200 print journals <strong>and</strong> provides connection<br />
to over 19000 electronic journals. The Library, which is the physical science <strong>and</strong> engineering<br />
library on the UNR campus, houses <strong>Chemical</strong> Abstracts <strong>and</strong> provides 24-hour access via<br />
SciFinder to the full <strong>Chemical</strong> Abstracts <strong>and</strong> Registry files online. Bound journal volumes <strong>and</strong><br />
an exhaustive collection of reference books (about 100000) are also housed there. Computer<br />
access to on-line retrieval services <strong>and</strong> databases is readily available, with assistance provided<br />
from our librarians. The online catalog provides instant information on holdings in the entire<br />
University of Nevada Library System <strong>and</strong> other libraries connected to the Internet.<br />
Reno: The Community <strong>and</strong> its Setting<br />
Reno is situated in a broad valley of the Truckee River on the eastern slope of the Sierra<br />
Nevada Mountains <strong>and</strong> on the western boundary of the Great Basin high desert. Reno weather<br />
is temperate due to the mountainous location <strong>and</strong> the elevation of 4500 feet. Summers are<br />
comfortable <strong>and</strong> dry with cool evening temperatures <strong>and</strong> low humidity. Despite heavy snow<br />
in the surrounding mountains, winters in Reno are moderate with only occasional, short-lived<br />
snowfalls. The average temperatures call for highs in January of 45 F <strong>and</strong> lows of 18 F. July<br />
temperatures range from a normal high of 91 F to a normal low of 50 F.<br />
Reno has long been famed as "The Biggest Little City in the World." With a population of<br />
about 400,000 in the greater Reno area, the region offers the advantages <strong>and</strong> excitement of<br />
a major urban area along with the quality of life characteristic of a relatively small western<br />
community. The major industry in Reno is tourism <strong>and</strong> the big names in show business can<br />
be found in the downtown <strong>and</strong> Lake Tahoe entertainment centers. Fine restaurants <strong>and</strong> night<br />
clubs exist in abundance.<br />
13
Reno also supports a thriving<br />
arts community rivaled by few<br />
cities of its size: philharmonic<br />
<strong>and</strong> chamber orchestras, a<br />
municipal b<strong>and</strong>, an opera<br />
guild, a performing artist series,<br />
a summer arts festival, <strong>and</strong><br />
active theater groups. Several<br />
art galleries, museums, <strong>and</strong> a<br />
planetarium are located on or<br />
near the university campus <strong>and</strong><br />
throughout the community.<br />
The municipally-owned Pioneer<br />
Center for the Performing Arts in downtown Reno <strong>and</strong> the Church Fine Arts Complex at the<br />
university provide fine settings for artistic <strong>and</strong> cultural events. The Convention Center near the<br />
southern edge of the city <strong>and</strong> the Lawlor Events Center on campus are used for indoor athletic<br />
activities such as basketball, for large concerts, conventions, <strong>and</strong> trade fairs.<br />
Many major special events <strong>and</strong> festivals are<br />
held in Reno on an annual basis. Examples include<br />
the National Championship Air Races, The<br />
Great Reno Balloon Race, Hot August Nights<br />
(a celebration of 50's music, cars, <strong>and</strong> culture),<br />
the Nevada State Fair <strong>and</strong> the Reno Rodeo ("the<br />
World's Wildest <strong>and</strong> Richest"). Reno is the home<br />
of the National Bowling Stadium, where bowling<br />
tournaments are held regularly. The nearby<br />
communities of Virginia City <strong>and</strong> Carson City are<br />
of interest to fans of the culture <strong>and</strong> history of the Old West.<br />
R<strong>and</strong> McNally's Vacation Places Rated has ranked Reno-Tahoe as the number one location<br />
in the nation for outdoor sports activities. Dozens of’ golf courses lie within an hour's drive of<br />
downtown Reno <strong>and</strong> numerous parks, swimming pools, <strong>and</strong> picnic areas are found within the<br />
city. The Truckee River, which runs from Lake Tahoe through Reno to Pyramid Lake, provides a<br />
natural parkway that winds through the heart of the city <strong>and</strong> a developed bicycle <strong>and</strong> pedestrian<br />
path follows its course. Reno is surrounded by public l<strong>and</strong>s that provide hiking <strong>and</strong> mountain<br />
biking opportunities immediately accessible<br />
from the city <strong>and</strong> the university campus.<br />
The Reno-Lake Tahoe area provides one of<br />
the highest concentration of developed alpine<br />
<strong>and</strong> nordic skiing facilities in the world <strong>and</strong> back<br />
country skiing opportunities are equally accessible.<br />
In summers, road <strong>and</strong> mountain biking,<br />
camping, hiking (including portions of the Pacific<br />
Crest Trail <strong>and</strong> the Tahoe Rim Trail), <strong>and</strong> rock<br />
climbing in the Sierra Nevada are unsurpassed.<br />
14
To the east of the city, the rugged mountains <strong>and</strong> isolation of<br />
the Great Basin desert challenge more adventurous outdoor<br />
enthusiasts with country as wild <strong>and</strong> remote as can be found<br />
in the West, including National Forests <strong>and</strong> National Wilderness<br />
Areas. Big game <strong>and</strong> bird hunting, as well as fishing, are outst<strong>and</strong>ing<br />
in the immediate Reno area <strong>and</strong> throughout the state.<br />
Special regional attractions include the winter sports complex<br />
at Squaw Valley, site of the 1960 Winter Olympics, one of the<br />
country’s largest cross-country ski resorts at Royal Gorge, <strong>and</strong><br />
the unique year-round recreational opportunities at Lake Tahoe<br />
<strong>and</strong> Pyramid Lake.<br />
Beyond the local area, Yosemite,<br />
Lassen Volcanic, Great Basin, Redwood,<br />
Crater Lake, Death Valley, <strong>and</strong><br />
Sequoia <strong>and</strong> King’s Canyon National<br />
Parks are located within a day’s drive from Reno. Interstate 80 leads<br />
west through Sacramento (about two <strong>and</strong> one-half hours), to the<br />
San Francisco Bay area (about four hours), passing through some of<br />
the finest mountain scenery in the nation.<br />
Reno is a major industry <strong>and</strong> trade center for the western<br />
geographic region. While gaming, mining, <strong>and</strong> agriculture remain<br />
the most important components of the regional economy, local<br />
industry, usually science-based <strong>and</strong> research oriented, is becoming<br />
an increasingly significant economic factor in the community.<br />
Reno is the headquarters for the Sierra Nevada Section of the American <strong>Chemical</strong> Society.<br />
Many of the faculty, students, <strong>and</strong> staff in the chemistry, biochemistry, <strong>and</strong> chemical engineering<br />
departments, the Desert Research Institute, <strong>and</strong> scientists in local government <strong>and</strong> industry<br />
are involved in local ACS activities.<br />
15
Mario A. Alpuche<br />
Assistant Professor<br />
Analytical, Physical <strong>and</strong> Materials <strong>Chemistry</strong><br />
E-mail: malpuche@unr.edu<br />
The development <strong>and</strong> application of electrochemical methods are the focus<br />
or our research. We are interested in using these methods to solve problems<br />
in analytical chemistry, energy conversion <strong>and</strong> corrosion.<br />
Renewable energy sources can be utilized with electrochemical devices<br />
such as fuel cells, batteries <strong>and</strong> dye-sensitized solar cells. We are interested<br />
in studying the fundamental properties<br />
of materials used for these applications to<br />
explain observed trends in electrocatalytic<br />
activity; we aim at using this knowledge to design new<br />
materials for more efficient devices. We apply electrochemical<br />
principles to study the thermodynamics <strong>and</strong> kinetics of<br />
electron transfer reactions to correlate these with structure<br />
<strong>and</strong> other properties of materials. We are interested in<br />
developing new methods for the analysis of nanostructures,<br />
films <strong>and</strong> bulk materials for their potential use in energy conversion, such as semiconductors for<br />
harvesting solar energy <strong>and</strong> electrocatalysts for fuel cells (see Fig. 1).<br />
Selected Publications<br />
1. “Photoelectrochemistry studies of the b<strong>and</strong> structure of Zn2SnO4 prepared by the hydrothermal<br />
method,” Alpuche-Aviles, M.A.; Wu, Y. Journal of the American <strong>Chemical</strong> Society<br />
2009, ASAP.<br />
2. “Interrogation of surfaces for the quantification of adsorbed species on electrodes: Oxygen<br />
on gold <strong>and</strong> platinum in neutral media,” Rodriguez Lopez, J.; Alpuche-Aviles, M.A.; Bard, A.J.<br />
Journal of the American <strong>Chemical</strong> Society 2008, 130, 16985-16995.<br />
3. “Cyclic voltammetry studies of Cd2+ <strong>and</strong> Zn2+ complexation with hydroxyl terminated<br />
polyamidoamine generation 2 dendrimer at a mercury microelectrode,” Nepomnyashchii,<br />
A.; Alpuche-Aviles, M.A.; Pan, S.; Zhan, D.; Fan, F.-R.; Bard, A.J. Journal of Electroanalytical<br />
<strong>Chemistry</strong> 2008, 621, 286-296.<br />
4. “Screening of oxygen evolution electrocatalysts by scanning electrochemical microscopy<br />
using a tip shielding approach,” Minguzzi, A.; Alpuche-Aviles, M.A.; Rodriguez Lopez, J.; Rondinini,<br />
S.; Bard, A.J. Analytical <strong>Chemistry</strong> 2008, 80, 4055-4064.<br />
5. “Imaging of metal ion dissolution <strong>and</strong> electrodeposition by anodic stripping voltammetryscanning<br />
electrochemical microscopy,” Alpuche-Aviles, M.A.; Baur, J.E.; Wipf, D.O. Analytical<br />
<strong>Chemistry</strong> 2008, 80, 3612-3621.<br />
6. “Scanning electrochemical microscopy. 59. Effect of defects <strong>and</strong> structure on electron transfer<br />
through self-assembled monolayers,” Kiani, A.; Alpuche-Aviles, M.A.; Eggers, P.; Jones, M.;.<br />
Gooding, J.J.; Paddon-Row, M.N.; Bard, A.J. Langmuir 2008, 24, 2841-2849.<br />
7. “Selective insulation with polytetrafluoroethylene of substrate electrodes for electrochemical<br />
background reduction in scanning electrochemical microscopy,” Rodriguez Lopez, J.;<br />
Alpuche-Avilés, M.A.; Bard, A.J. Analytical <strong>Chemistry</strong> 2008, 80, 1813-1818.<br />
8. “Fast-scan cyclic voltammetry - scanning electrochemical microscopy,” Luis Díaz-Ballote, L.;<br />
Alpuche-Avilés, M.A.; Wipf, D.O. Journal of Electroanalytical <strong>Chemistry</strong> 2007, 604, 17-25.<br />
32 - Faculty<br />
B.S. (Licenciatura, 1999) Autonomous University of<br />
Yucatan; Ph.D. (2005), Mississippi State University<br />
(David Wipf); Postdoctoral Fellow (2005-2007), The<br />
University of Texas at Austin, Center for Electrochemistry<br />
(Allen J. Bard), <strong>and</strong> (2007-2009) The Ohio State<br />
University (Yiying Wu).
FRANK G. BAGLIN<br />
Professor<br />
Physical <strong>Chemistry</strong>; <strong>Chemical</strong> <strong>Physics</strong><br />
E-mail: baglin@unr.edu<br />
16 - Faculty<br />
B.S. (1963), Michigan State University; Ph.D. (1967),<br />
Washington State University (E.L. Wagner); Postdoctoral<br />
(1967-68), NIH Postdoctoral Fellow, University of South<br />
Carolina (J.R. Durig); Alex<strong>and</strong>er Van Humboldt Fellow<br />
(1981-83), University of Dortmund (Heiner Versmold).<br />
Generally, our interests focus on the electro-optical properties of supracritical<br />
dense gases. Because of the supracritical property we can vary the density<br />
with complete freedom without condensation taking place. This allows us to<br />
probe the intermolecular potential of the system via interaction induced (ii)<br />
Raman light scattering. The Raman spectral intensity, I, may be written as<br />
I = 2 N 2 2 + 4 N 3 + N 4 <br />
where N is the number density <strong>and</strong> the m ij ’s are the induced spectral moments.<br />
The N 3 term’s moments are negative so at high enough density<br />
values the spectral intensity will begin to fall off sharply. Thus, the Raman ii<br />
signal may be thought of as arising from local density fluctuations giving rise to transient local<br />
field gradients.<br />
Most recently, we have been investigating<br />
neat methane <strong>and</strong> methane solution<br />
spectra at supracritical conditions. We have<br />
seen that the Raman depolarization ratios<br />
(RDR) track the ultra-strong rotation-vibration<br />
coupling (coriolis constant) in the methane<br />
molecule. The RDR changes very rapidly<br />
at elevated densities (pressure) indicating<br />
changes in the intermolecular potential<br />
function. Depending upon the molecules<br />
surrounding the methane, the position of<br />
the sigmoidal curves will shift reflecting the<br />
inter-body potential change. In the figure above, frequency shifts are denoted by triangles <strong>and</strong><br />
the RDR data by squares.<br />
Intermolecular Raman light scattering depends upon the electron polarizabilty between<br />
molecules. As the molecules move the polarizability must change. Thus, as the molecular<br />
motion fluctuates so does the polarizabilty. As a result, the polarizability tracks the molecular<br />
positional fluctuations.<br />
Selected Publications<br />
1. “An interpretation of the solute-solvent interactions in supercritical binary fluids as monitored<br />
by interaction-induced Raman light scattering,” Palmer, T.; Stanbery, W.; Baglin, F.G. J.<br />
Mol. Liqs. 2000, 85, 153.<br />
2. “Interaction-induced Raman light scattering as a probe of the local density of binary supercritical<br />
solutions,” Baglin, F.G.; Murray, S.K.; Daugherty, J.E.; Palmer, T.E.; Stanbery, W. Mol. Phys.<br />
2000, 98, 409.<br />
3. “Interaction induced Raman light scattering studies of CH4<br />
/H mixtures as a function of<br />
2<br />
density,” Baglin, F.G.; Sweitzer, S.; Friend, D.G. J. Phys. Chem. B 1997, 101, 8816-8822.<br />
4. “Raman light scattering from supracritical binary fluid mixtures: CH4<br />
/CF ” Baglin, F.G.;<br />
4,<br />
Sweitzer, S.; Stanbery, W.J. Chem. Phys. 1996, 105, 7285.<br />
5. “Identification of 1, 2 <strong>and</strong> 3 body Raman scattering by the field gradient induced dipole A<br />
tensor in methane,” Baglin, F.G.; Rose, E.J.; Sweitzer, S. Mol. Phys. 1995, 84, 115.
THOMAS W. BELL<br />
Professor<br />
Organic <strong>and</strong> Bioorganic <strong>Chemistry</strong><br />
E-mail: twb@unr.edu<br />
Our research projects draw upon concepts <strong>and</strong> methods in synthetic <strong>and</strong><br />
physical organic chemistry, coordination chemistry, spectroscopy <strong>and</strong> structural<br />
chemistry. The unifying theme is molecular devices: molecules that<br />
are tailored to bind <strong>and</strong> sense other molecules, to act as switches or motors,<br />
or to act as drugs interfering with biochemical processes.<br />
We have made artificial receptors by fusing rings, particularly pyridine,<br />
that can bind guest molecules by forming hydrogen bonds. These “hexagonal<br />
lattice receptors” can be tailored to bind analytes of medical interest<br />
<strong>and</strong> report their concentrations by an<br />
optical response. Two examples are a<br />
chromogenic reagent for measuring<br />
blood creatinine, which is an indicator of<br />
kidney function, <strong>and</strong> a fluorescent sensor<br />
for bicarbonate ion.<br />
Our third research area is aimed at<br />
novel antiviral drugs. We have synthesized<br />
a series of compounds, called<br />
CADA analogs, that are active against<br />
several viruses, including HIV. Our approach<br />
to new drugs for AIDS is to synthesize<br />
<strong>and</strong> test compounds designed<br />
on the basis of proposed mechanisms of action.<br />
Selected Publications<br />
1. “Design <strong>and</strong> cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV <strong>and</strong> CD4<br />
receptor down-modulating activity,” Vermeire, K.; Lisco, A.; Grivel, J.-C.; Scarbrough, E.; Dey, K.;<br />
Duffy, N.; Margolis, L.; Bell, T.W.; Schols, D. Biochemical Pharmacology 2007, 74, 566-578.<br />
2. “Synthesis <strong>and</strong> structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide<br />
(CADA) analogs,” Bell, T.W.; Anugu, S.; Bailey, P.; Catalano, V.J.; Dey, K.; Drew,<br />
M.G.B.; Duffy, N.H.; Jin, Q.; Samala, M.F.; Sodoma, A.; Welch, W.H.; Schols, D.; Vermeire, K. J.<br />
Med. Chem. 2006, 49, 1291-1312.<br />
3. “A D2 symmetric tetraamide macrocycle based on 1,10,4,40-tetrahydro[3,30(2H,20H)spirobiquinoline]-2,20-dione:<br />
Synthesis <strong>and</strong> selectivity for lithium over sodium <strong>and</strong> alkaline<br />
earth ions,” Choi, H.-J.; Park, Y.S.; Kim, M.G.; Park, Y.J.; Yoon, N.S.; Bell, T.W. Tetrahedron 2006,<br />
8696-8701.<br />
4. “CD4-targeted HIV inhibitors,” Vermeire, K.; Schols, D.; Bell, T.W. Curr. Med. Chem. 2006, 13,<br />
731-743.<br />
5. “Syntheses, structures, <strong>and</strong> photoisomerization of ( E)- <strong>and</strong> (Z)-2-tert-butyl-9-(2,2,2)-triphenyethylidenefluorene,”<br />
Barr, J.W.; Bell, T.W.; Catalano, V.J.; Cline, J.I.; Phillips, D.J.; Procupez, R. J.<br />
Phys. Chem. 2005, A 109, 11650-11654.<br />
6. “CD4 down-modulating compounds with potent anti-HIV activity,” Vermeire, K.; Schols, D.;<br />
Bell, T.W. Curr. Pharmaceut. Design 2004, 10, 1795-1803.<br />
17 - Faculty<br />
B.S. (1974), California Institute of Technology; Ph.D.<br />
(1980), University College, University of London (F.<br />
Sondheimer); NIH Postdoctoral Fellow (1980-82),<br />
Cornell University (J. Meinwald); Fellow of the<br />
American Association for the Advancement of Science<br />
(1995-present).
ANA de BETTENCOURT-DIAS<br />
Associate Professor<br />
Inorganic <strong>and</strong> Materials <strong>Chemistry</strong><br />
E-mail: abd@unr.edu<br />
Our group is interested in the luminescent properties of lanthanide ion<br />
complexes <strong>and</strong> of materials containing lanthanide ions, as well as the<br />
coordination chemistry of the f elements. Lanthanide ions are utilized in<br />
luminescence applications, as they display strong light emission with high<br />
color purity. The emission is based on f-f transitions, which are spin- <strong>and</strong> parity<br />
forbidden. Therefore, to efficiently populate the emissive excited state,<br />
sensitizers or antennas are utilized. We synthesize <strong>and</strong> characterize new<br />
antennas <strong>and</strong> study the photophysical properties of the new lig<strong>and</strong>s <strong>and</strong> of<br />
the corresponding lanthanide ion complexes.<br />
The synthetic strategy followed in<br />
our research group involves utilizing<br />
thiophene in our lig<strong>and</strong>s, which will<br />
allow us to incorporate lig<strong>and</strong>s of metal<br />
complexes into organic polymers to<br />
make luminescent films. The thiophene<br />
group is derivatized with selected moieties<br />
capable of coordinating lanthanide<br />
ions <strong>and</strong> sensitizing their luminescence.<br />
Comparison of the structure-properties<br />
relationship of the synthesized lig<strong>and</strong>s<br />
<strong>and</strong> of the corresponding metal complexes<br />
allows us to optimize our systems<br />
for applications such as light-emitting<br />
diodes.<br />
Selected Publications<br />
1. “Lanthanide-based emitting materials in light-emitting diodes,” de Bettencourt-Dias, A.<br />
Dalton Trans. 2007, 2229-2241.<br />
2. “Exploring lanthanide luminsecence in metal-organic frameworks: Synthesis, structure,<br />
<strong>and</strong> guest sensitized luminescence of a mixed europium/terbium-adipate framework <strong>and</strong><br />
a terbium-adipate framework,” de Lill, D.T.; de Bettencourt-Dias, A.; Cahill, C.L. Inorg. Chem.<br />
2007, 46, 3960-3965.<br />
3. “Small molecule luminescent lanthanide ion complexes - Photophysical characterization<br />
<strong>and</strong> recent developments,” de Bettencourt-Dias, A. Curr. Org. Chem. 2007, in press.<br />
4. “Phenylthiophene-dipicolinic acid-based with strong solution blue <strong>and</strong> solid state green<br />
emission,” de Bettencourt-Dias, A.; Poloukhtine, A. J. Phys. Chem. B 2006, 110, 25638-25645.<br />
5. “Eu(III) <strong>and</strong> Tb(III) luminescence sensitized by thiophenyl-derivatized nitrobenzoato antennas,”<br />
Viswanathan, S.; de Bettencourt-Dias, A. Inorg. Chem. 2006, 45, 10138-10146.<br />
6. “Nitro-functionalization <strong>and</strong> quantum yield of Eu(III) <strong>and</strong> Tb(III) benzoic acid complexes,” de<br />
Bettencourt-Dias, A.; Viswanathan, S. Dalton Trans. 2006, 4093-4103.<br />
7. “2-Chloro-5-nitrobenzoato complexes of Eu(III) <strong>and</strong> Tb(III) - A 1 D coordination polymer <strong>and</strong><br />
enhanced solution luminescence,” Viswanathan, S.; de Bettencourt-Dias, A. Inorg. Chem.<br />
Comm. 2006, 9, 444-448.<br />
18 - Faculty<br />
Licenciatura (1993), University of Lisbon, Portugal;<br />
Dr. rer. nat. (1997), magna cum laude, University of<br />
Cologne, Germany (T. Kruck); Gulbenkian Postdoctoral<br />
Fellow (1998-2001), University of California,<br />
Davis (A.L. Balch).
SEAN M. CASEY<br />
Associate Professor<br />
Physical <strong>and</strong> Surface <strong>Chemistry</strong>; <strong>Chemical</strong> <strong>Physics</strong><br />
E-mail: scasey@unr.edu<br />
19 - Faculty<br />
B.S. (1988), State University of New York, College at<br />
Purchase; Ph.D. (1993), University of Minnesota (D.G.<br />
Leopold); NRC-NIST Postdoctoral Fellow (1993-95)<br />
<strong>and</strong> Postdoctoral (1995-97), JILA, University of<br />
Colorado (S.R. Leone).<br />
Our research is centered on the investigation of growth mechanisms of<br />
semiconductor materials during processes such as plasma-enhanced chemical<br />
vapor deposition (PECVD). To mimic these plasmas under more carefully<br />
controlled conditions, we use a hyperthermal beam of the reactive species of<br />
interest <strong>and</strong> single crystal semiconductor<br />
wafers. Specifically,<br />
we generate a variable energy<br />
beam of mass-selected, reactive<br />
atomic or molecular ions, with<br />
energies in the 1 - 100 eV range, <strong>and</strong> use this as<br />
the source of growth species. The interaction<br />
of these species with clean, well characterized<br />
semiconductor surfaces is then examined in an<br />
ultrahigh vacuum environment (pictured below).<br />
Mass spectrometry is used to examine the identity<br />
of desorbing <strong>and</strong> scattered species <strong>and</strong> to provide<br />
kinetic information about reactions occurring on<br />
the surface. Low-energy electron diffraction <strong>and</strong><br />
Auger electron spectroscopy are used to examine<br />
the crystallinity <strong>and</strong> composition of the resulting<br />
surfaces. Results from such experiments allow for<br />
a more complete underst<strong>and</strong>ing of the mechanisms<br />
involved in reactive ion-surface interactions,<br />
an area of great importance during these PECVD processes.<br />
Selected Publications<br />
1. “Gas phase chemomechanical modification of silicon,” Lee, M.V.; Richards, J.L.; Linford, M.R.;<br />
Casey, S.M. J. Vac. Sci. Technol. B 2006, 24, 750-755.<br />
2. “Molecularly designed chromonic liquid crystals for the fabrication of broad spectrum<br />
polarizing materials,” Tam-Chang, S.-W.; Seo, W.; Rove, K.O.; Casey, S.M. Chem. Mater. 2004,<br />
16, 1832-1834.<br />
3. “Adsorption <strong>and</strong> thermal decomposition chemistry of 1-propanol <strong>and</strong> other primary alcohols<br />
on the Si(100) surface,” Zhang, L.; Carman, A.J.; Casey, S.M. J. Phys. Chem. B 2003, 107,<br />
8424-8432.<br />
4. “Novel polarized photoluminescent films derived from sequential self-organization,<br />
induced-orientation, <strong>and</strong> order transfer processes,” Carson, T.D.; Seo, W.; Tam-Chang, S.-W.;<br />
Casey, S.M. Chem. Mater. 2003, 15, 2292-2294.<br />
5. “Adsorption <strong>and</strong> thermal decomposition chemistry of 1-propanol <strong>and</strong> other primary alcohols<br />
on the Si(100) surface,” Zhang, L.; Carman, A.J.; Casey, S.M. J. Phys. Chem. B 2003, 107,<br />
8424-8432.<br />
6. “Novel polarized photoluminescent films derived from sequential self-organization,<br />
induced-orientation, <strong>and</strong> order transfer processes,” Carson, T.D.; Seo, W.; Tam-Chang, S.-W.;<br />
Casey, S.M. Chem. Mater. 2003, 15, 2292-2294. [Communication]
VINCENT J. CATALANO<br />
Professor <strong>and</strong> Chair<br />
Inorganic <strong>Chemistry</strong><br />
E-mail: vjc@unr.edu<br />
20 - Faculty<br />
B.S. (1987), University of California, Santa Barbara;<br />
Ph.D. (1991), University of California, Davis (A.L.<br />
Balch); NSF Postdoctoral Fellow (1992-93), California<br />
Institute of Technology (H.B. Gray).<br />
Our research interests include the synthesis, structure, bonding <strong>and</strong><br />
optical properties of transition metal complexes. We are currently exploring<br />
the application of N-heterocyclic carbene (NHC) lig<strong>and</strong>s as supports for<br />
maintaining short metal-metal interactions between closed-shell ions,<br />
particularly Au(I) <strong>and</strong> Ag(I). With these lig<strong>and</strong>s we are able to prepare highly<br />
luminescent, one-dimensional coordination polymers that contain very<br />
short metal-metal separations. Perturbing this metal-metal separation either<br />
through intercalation or coordination alters the emission properties making<br />
these molecules ideally suited for applications as luminescent sensors.<br />
Additionally, synthetically manipulating the<br />
NHC backbone to include specific receptor<br />
moieties, introduces selectivity for analyte<br />
sensing. Receptors for nitro arenes as mimics<br />
for explosives are or particular interest.<br />
Additionally, the physical <strong>and</strong> optical<br />
properties of discrete NHC bridged dimers<br />
are being explored as models for the larger<br />
extended polymeric systems.<br />
All of these complexes are probed with a<br />
variety of techniques including multinuclear<br />
NMR, electronic absorption <strong>and</strong> emission<br />
spectroscopy <strong>and</strong> single crystal X-ray<br />
diffraction.<br />
Selected Publications<br />
1. “Preparation of Au(I), Ag(I), <strong>and</strong> Pd(II) N-heterocyclic carbene complexes utilizing a<br />
methylpyridyl-substituted NHC lig<strong>and</strong>. Formation of a luminescent coordination polymer,”<br />
Catalano, V.J.; Etogo, A.O. Inorg. Chem. 2007, 46, 5608-5615.<br />
2. “Luminescent coordination polymers with extended Au(I)-Ag(I) interactions supported by<br />
a pyridine substituted NHC lig<strong>and</strong>,” Catalano, V.J.; Etogo, A.O. J. Organomet. Chem. (Special<br />
Carbene Issue) 2005, 690, 6041-6050.<br />
3. “Mono-, di-, <strong>and</strong> trinuclear luminescent silver(I) <strong>and</strong> gold(I) N-heterocyclic carbene<br />
complexes derived from the picolyl-substituted methylimidazolium salt: 1-methyl-3-(2pyridinylmethyl)-1H-imidazolium<br />
tetrafluoroborate,” Catalano, V.J.; Moore, A.L. Inorg. Chem.<br />
2005, 44, 6558-6566.<br />
4. “Pyridine substituted N-heterocyclic carbene lig<strong>and</strong>s as supports for Au(I)–Ag(I) interactions:<br />
Formation of a chiral coordination polymer,” Catalano, V.J.; Malwitz, M.A.; Etogo, A.O. Inorg.<br />
Chem. 2004, 43, 5714-5724.<br />
5. “Mixed-metal metallocrypt<strong>and</strong>s. Short metal-metal separations stabilized by dipolar<br />
interactions,” Catalano, V.J.; Malwitz, M.A. J. Am. Chem. Soc. 2004, 126, 6560-6561.<br />
6. “Metallocrypt<strong>and</strong>s: Host complexes for probing closed-shell metal-metal interactions,”<br />
Catalano, V.J.; Bennett, B.L.; Malwitz, M.A.; Yson, R.L.; Kar, H.M.; Muratidis, S.; Horner, S.J.<br />
Comments on Inorganic <strong>Chemistry</strong> 2003, 24, 24-68.
JOSEPH I. CLINE<br />
Professor<br />
Physical <strong>Chemistry</strong>; <strong>Chemical</strong> <strong>Physics</strong><br />
E-mail: cline@unr.edu<br />
21 - Faculty<br />
B.S. (1983), University of Virginia; Ph.D. (1988),<br />
California Institute of Technology (K.C. J<strong>and</strong>a);<br />
Postdoctoral (1988-90), JILA, University of Colorado<br />
(S.R. Leone).<br />
Research interests center around the<br />
experimental investigation of inelastic<br />
molecular collisions, vibrational<br />
predissociation in weakly-bound<br />
complexes, photodissociation of<br />
molecules, <strong>and</strong> gas-phase chemical<br />
kinetics. Molecular beam techniques<br />
<strong>and</strong> time-of-flight mass spectrometry<br />
detection are used in conjunction<br />
with laser spectroscopic probes to study these chemical<br />
processes with electronic, vibrational, rotational, <strong>and</strong><br />
translational quantum-state resolution. Experimental<br />
measurements are interpreted using theoretical models<br />
for these dynamic processes. Construction of realistic potential energy surfaces from dynamical<br />
measurements on complex systems is one major goal of our research.<br />
Selected Publications<br />
2 1. “Ion imaging studies of product rotational alignment in collisions of NO (X Π1/2 , j=0.5) with<br />
Ar,” Wade, E.A.; Lorenz, K.T.; Ch<strong>and</strong>ler, D.W.; Barr, J.W.; Barnes, G.L.; Cline, J.I. Chem. Phys. 2004,<br />
301, 261-272.<br />
2. “Ion Imaging Applied to the Study of <strong>Chemical</strong> Dynamics,” David W. Ch<strong>and</strong>ler <strong>and</strong> Joseph I.<br />
Cline, in X. Yang <strong>and</strong> K. Liu, eds. Modern Trends In <strong>Chemical</strong> Reaction Dynamics, Part I: Experiment<br />
<strong>and</strong> Theory Advanced Series in Physical <strong>Chemistry</strong> Vol. 14 (World Scientific: 2004), pgs.<br />
61-104.<br />
3. “Direct measurement of the binding energy of the NO dimer,” Wade, E.A.; Cline, J.I.; Lorenz,<br />
K.T.; Hayden, C.; Ch<strong>and</strong>ler, D.W. J. Chem. Phys. 2002, 116, 4755-4757.<br />
4. “Measurement of bipolar moments for photofragment angular correlations in ion imaging<br />
experiments,” Nestorov, V.K.; Hinchliffe, R.D.; Uberna, R.; Cline, J.I.; Lorenz, K.T.; Ch<strong>and</strong>ler, D.W.<br />
J. Chem. Phys. 2001, 115, 7881-7891.<br />
5. “Ion imaging measurement of collision-induced rotational alignment in Ar-NO scattering,”<br />
Cline, J.I.; Lorenz, K.T.; Wade, E.A.; Barr, J.W.; Ch<strong>and</strong>ler, D.W. J. Chem. Phys. 2001, 115,<br />
6277-6280.<br />
6. “Direct measurement of the preferred sense of NO rotation after collision with argon,”<br />
Lorenz, K.T.; Ch<strong>and</strong>ler, D.W.; Barr, J.W.; Chen, W.; Barnes, G.L.; Cline, J.I. Science 2001, 293,<br />
2063-2066.<br />
7. “Determination of μ-v-j vector correlations in photodissociation experiments using 2+n<br />
resonance-enhanced multiphoton ionization with time-of-flight mass spectrometry detection,”<br />
Pisano, P.J.; Cline, J.I. J. Chem. Phys. 2000, 112, 6190.<br />
8. “Detection of ‘ended’ NO recoil in the 355 nm NO photodissociation mechanism,” Nestorov,<br />
2<br />
V.K.; Cline, J.I. J. Chem. Phys. 1999, 111, 5287-5290.<br />
9. “Scalar <strong>and</strong> angular correlations in CF NO photodissociation: Statistical <strong>and</strong> nonstatistical<br />
3<br />
channels,” Spasov, J.S.; Cline, J.I. J. Chem. Phys. 1999, 110, 9568-9577.
KENT M. ERVIN<br />
Professor<br />
Physical <strong>and</strong> Analytical <strong>Chemistry</strong>; <strong>Chemical</strong> <strong>Physics</strong><br />
E-mail: ervin@unr.edu<br />
22 - Faculty<br />
B.S., B.A. (1981), University of Kansas; Ph.D. (1986),<br />
University of California, Berkeley (P.B. Armentrout);<br />
Postdoctoral (1986-90), JILA, University of Colorado<br />
(W.C. Lineberger).<br />
T<strong>and</strong>em mass spectrometry techniques are used to study chemical systems<br />
relevant to combustion kinetics <strong>and</strong> the dissociation dynamics of molecular<br />
ions. Two custom-built t<strong>and</strong>em mass spectrometers have been developed<br />
for these studies: a guided ion beam t<strong>and</strong>em mass spectrometer with a<br />
magnetic sector initial mass spectrometer <strong>and</strong> a 2D quadrupole final mass<br />
spectrometer, <strong>and</strong> a crossed ion beam/molecular beam apparatus with<br />
a 3D quadrupole ion trap initial mass spectrometer <strong>and</strong> a time-of-flight<br />
mass spectrometer for detection. Both systems allow the measurement of<br />
ion-molecule reactions as a function of collision energy <strong>and</strong> time-resolved<br />
examination of photodissociation processes.<br />
In addition, laser-induced fluorescence studies<br />
of ions may be conducted in the ion trap.<br />
Current research focuses on the following<br />
projects:<br />
Proton transfer <strong>and</strong> hydrogen atom<br />
transfer reactions of organic molecules are<br />
used to investigate thermochemical properties<br />
of hydrocarbon radicals important in<br />
combustion kinetics <strong>and</strong> environmental<br />
chemistry. Reaction threshold energies<br />
measured with the guided ion beam mass<br />
spectrometer can be related to the R-H bond<br />
dissociation energies. Competitive threshold<br />
collision-induced dissociation of protonbound<br />
complex ions is used to measure<br />
relative gas-phase acidities <strong>and</strong> proton affinities. Product velocity distributions are investigated<br />
to probe microscopic reaction mechanisms <strong>and</strong> the energy disposal into vibrational <strong>and</strong> translational<br />
degrees of freedom.<br />
Selected Publications<br />
1. “Gas-phase acidities <strong>and</strong> O-H bond dissociation enthalpies of phenol, 3-methylphenol,<br />
2,4,6-trimethylphenol, <strong>and</strong> ethanoic acid,” Angel, L.A.; Ervin, K.M. J. Phys. Chem. A 2006, 110,<br />
10392.<br />
2. “Collision-induced dissociation of HS-(HCN): Unsymmetrical hydrogen bonding in a protonbound<br />
dimer anion,” Akin, F.A.; Ervin, K.M. J. Phys. Chem. A 2006, 110, 1342.<br />
3. “Threshold collision-induced dissociation of diatomic molecules: A case study of the ener-<br />
- getics <strong>and</strong> dynamics of O collisions with Ar <strong>and</strong> Xe,” Akin, F.A.; Ree, J.; Ervin, K.M.; Shin, H.K.<br />
2<br />
J. Chem. Phys. 2005, 123, 064308.<br />
4. “Systematic <strong>and</strong> r<strong>and</strong>om errors in ion affinities <strong>and</strong> activation entropies from the extended<br />
kinetic method,” Ervin, K.M.; Armentrout, P.B. J. Mass Spectrom. 2004, 39, 1004-1015.<br />
5. “Competitive threshold collision-induced dissociation: Gas-phase acidity <strong>and</strong> O-H bond dissociation<br />
enthalpy of phenol,” Angel, L.A.; Ervin, K.M. J. Phys. Chem. A 2004, 108, 8346-8352.<br />
6. “Gas-phase reactions of the iodide ion with chloromethane <strong>and</strong> bromomethane: Competition<br />
between nucleophilic displacement <strong>and</strong> halogen abstraction,” Angel, L.A.; Ervin, K.M. J.<br />
Phys. Chem. A 2004, 108, 9827-9833.
BRIAN J. FROST<br />
Assistant Professor<br />
Inorganic <strong>and</strong> Organometallic <strong>Chemistry</strong>; Catalysis<br />
E-mail: frost@unr.edu<br />
23 - Faculty<br />
B.S. (1995), Elizabethtown College; Ph.D. (1999),<br />
Texas A&M University (D.J. Darensbourg); Postdoctoral<br />
Research Associate (2000-02), Columbia University<br />
(J.R. Norton).<br />
Organometallic chemistry <strong>and</strong> catalysis remain exciting areas of research<br />
with many opportunities for fundamental, not to mention pedagogical,<br />
contributions. We are interested in the synthesis, structure, <strong>and</strong> reactivity of<br />
inorganic <strong>and</strong> organometallic complexes with emphasis on those applicable<br />
to catalysis. Our research program encompasses a wide range of interests<br />
including: (1) green chemistry, (2) coordination chemistry, (3) catalysis in<br />
aqueous, organic, <strong>and</strong> biphasic media, (4) kinetic <strong>and</strong> mechanistic studies of<br />
catalytic processes, (5) small molecule activation, (6) lig<strong>and</strong> synthesis.<br />
Currently our group is working on projects involving the synthesis <strong>and</strong> characterization of<br />
new water-soluble phosphines, <strong>and</strong> exploring the catalytic activity of water-soluble inorganic<br />
<strong>and</strong> organometallic complexes. We are also interested in utilizing carbon dioxide, or a CO 2<br />
equivalent, as a C1 feedstock. We attempt to bring together aspects of inorganic, organic, <strong>and</strong><br />
organometallic chemistry. One of the projects currently underway in our laboratory involves<br />
the synthesis of the water-soluble ruthenium hydride shown below <strong>and</strong> investigating its utility<br />
as an aqueous-phase hydrogenation catalyst, <strong>and</strong> its reactivity with acids <strong>and</strong> bases.<br />
Selected Publications<br />
1. “Isomerization of trans-[Ru(PTA) Cl ] to cis-[Ru(PTA) Cl ] in water <strong>and</strong> organic solvent: Revisit-<br />
4 2 4 2<br />
ing the chemistry of [Ru(PTA) Cl ],” Mebi, C.A.; Frost, B.J. Inorg. Chem. 2007, 46, 7115-7120.<br />
4 2<br />
2.<br />
3.<br />
4.<br />
5.<br />
6.<br />
“pH dependent selective transfer hydrogenation of α,β-unsaturated carbonyls in aqueous<br />
media utilizing half-s<strong>and</strong>wich ruthenium (II) complexes,” Mebi, C.A.; Nair, R.P.; Frost, B.J. Organometallics<br />
2007, 26, 429-438.<br />
“Synthesis <strong>and</strong> coordination chemistry of a novel bidentate phosphine,<br />
6-(diphenylphosphino)-1,3,5-triaza-7-phosphaadamantane (PTA-PPh 2 ),” Wong, G.W.;<br />
Harkreader, J.L.; Mebi, C.A.; Frost, B.J. Inorg. Chem. 2006, 45, 6748-6755.<br />
“Manganese complexes of 1,3,5-triaza-7-phosphaadamantane (PTA): The first nitrogen<br />
bound transition metal complex of PTA,” Frost, B.J.; Bautista, C.M.; Huang, R.; Shearer, J. Inorg.<br />
Chem. 2006, 45, 3481-3483.<br />
“Boron-nitrogen adducts of 1,3,5-triaza-7-phosphaadamantane (PTA): Synthesis, reactiv-<br />
ity, <strong>and</strong> molecular structure,” Frost, B.J.; Mebi, C.A.; Gingrich, P.W. Eur. J. Inorg. Chem. 2006,<br />
1182-1189.<br />
“Effect of pH on the biphasic catalytic hydrogenation of benzylidene acetone using<br />
CpRu(PTA) H,” Mebi, C.A.; Frost, B.J. Organometallics 2005, 24, 2339-2346.<br />
2
Christopher S. Jeffrey<br />
Assistant Professor<br />
Organic, Bioorganic, <strong>and</strong> Organometallic <strong>Chemistry</strong><br />
Email:<br />
Research in the Jeffrey laboratory is focused on addressing important,<br />
unmet challenges in target directed synthesis. Areas of research are<br />
identified using a synergistic approach where (1) inspiration from structurally<br />
<strong>and</strong> biologically interesting molecular targets drives reaction<br />
discovery, <strong>and</strong> (2) innovation in methodology enables new strategies<br />
for target-directed synthesis.<br />
Some preliminary areas of research in our laboratory are focused on<br />
the development of new methods/strategies to generate <strong>and</strong> control<br />
electrophilic nitrogen species that will enable the direct functionalization of alkenes <strong>and</strong><br />
C-H bonds-the two most ubiquitous functional groups in organic molecules. These research<br />
interests are focused on the development of: (i) new hetero-cycloaddition reactions, (ii) a<br />
concise <strong>and</strong> general synthesis of a family of biologically active alkaloids, <strong>and</strong> (iii) new methods<br />
of metal-mediated amination.<br />
Selected Publications<br />
1. “Dynamic Kinetic Resolution During a Vinylogous Payne Rearrangement: A Concise<br />
Synthesis of the Polar Pharmacophoric Subunit of (+)-Scyphostatin,” Hoye, T.R.; Jeffrey, C.S.;<br />
Nelson, D.P. Org. Lett. 2010, 12, 52–55.<br />
2. “A Hypervalent Iodine-Induced Double Annulation Enables a Concise Synthesis of the<br />
Pentacyclic Core Structure of the Cortistatins,” Frie, J.L.; Jeffrey, C.S.; Sorensen, E.J. Org. Lett.<br />
2009, 11, 5394–5397.<br />
3. “Mosher Ester Analysis for the Determination of Absolute Configuration of Stereogenic<br />
(a.k.a. Chiral) Carbinol Carbons,” Hoye, T.R.; Jeffrey, C.S.; Shao, F. Nature Protocols 2007, 2,<br />
2451-2458.<br />
4. “The Structure Determination of the Sulfated Steroids PSDS <strong>and</strong> PADS – New Components<br />
of the Sea Lamprey (Petromyzon marinus) Migratory Pheromone,” Hoye, T.R.; Dvornikovs,<br />
V.; Fine, J.M.; Anderson, K.R.; Jeffrey, C.S.; Muddiman, D.C.; Shao, F.; Sorensen, P.W.; Wang, J. J.<br />
Org. Chem. 2007, 72, 7544-7550.<br />
5. “Student Empowerment through ‘Mini-Microscale’ Reactions: The Epoxidation of 1.0 mg of<br />
Geraniol,” Hoye, T.R.; Jeffrey, C.S. J. Chem. Educ. 2006, 83, 919-920.<br />
6. “Mixture of New Sulfated Steroids Functions as a Migratory Pheromone in the Sea Lamprey,”<br />
Sorensen, P.W.; Fine, J.M.; Dvornikovs, V.; Jeffrey, C.S.; Shao, F.; Wang, J.; Vrieze, L.A.;<br />
Anderson, K.R.; Hoye, T.R. Nature Chem. Biol. 2005, 1, 324-328.<br />
7. “Relay Ring-Closing Metathesis (RRCM): A Strategy for Directing Metal Movement Throughout<br />
Olefin Metathesis Sequences,” Hoye, T.R.; Jeffrey, C.S.; Tennakoon, M.A.; Wang, J.; Zhao,<br />
H. J. Am. Chem. Soc. 2004, 126, 10210-10211.<br />
33 - Faculty<br />
B.S. (2002), Carroll College; Ph.D. (2007), University<br />
of Minnesota (Thomas R. Hoye); Postdoctoral Fellow<br />
(2007-2010), Princeton University (Erik J. Sorensen).
BENJAMIN T. KING<br />
Associate Professor<br />
Organic <strong>Chemistry</strong><br />
E-mail: king@unr.edu<br />
24 - Faculty<br />
B.S. (1992), Northeastern University; Ph.D. (2000),<br />
University of Colorado (J. Michl); NIH Postdoctoral<br />
Fellow (2000-02), University of California, Berkeley<br />
(R.G. Bergman).<br />
Our research focuses on the preparation of molecules that might someday<br />
serve as useful materials. The approach is to design synthetic targets using<br />
computational chemistry, prepare them by chemical synthesis, <strong>and</strong> then<br />
study their properties <strong>and</strong> behavior.<br />
The benzenoid unit is a particularly versatile building block for nanostructures,<br />
as demonstrated by graphite, fullerenes, <strong>and</strong> carbon nanotubes. We<br />
are interested in constructing benzenoid nanostructures using controlled organic<br />
synthesis instead of the normal high temperature arc discharge methods.<br />
Two of our molecular targets are shown below. The short nanotubes<br />
might nucleate the growth<br />
of longer nanotubes <strong>and</strong> the<br />
extended helicenes might serve<br />
as molecular actuators.<br />
Since the incorporation of<br />
fluorine into molecules often<br />
confers unusual properties, such<br />
as high stability (e.g., Teflon®) or<br />
the ability to attain high oxidation<br />
states (e.g., XeF 2 ), the preparation of highly fluorinated nanostructures is another goal. Our<br />
initial targets are perfluorinated fullerenes, which are expected to be good electron acceptors.<br />
This work is safely carried out in specialized vacuum manifolds.<br />
Selected Publications<br />
1. “Polycyclic aromatic hydrocarbons by ring closing metathesis,” Bonifacio, M.C.; Robertson,<br />
C.R.; Jung, J.-Y.; King, B.T. J. Org. Chem. 2005, 70, 8522-8526.<br />
2. “A slippery slope: Mechanistic analysis of the intramolecular Scholl reaction of hexaphenylbenzene,”<br />
Rempala, P.; Kroulík, J.; King, B.T. J. Am. Chem. Soc. 2004, 126, 15002-15003.<br />
3. “Clar valence bond representation of π-bonding in carbon nanotubes,” Ormsby, J.; King, B.T.<br />
J. Org. Chem. 2004, 69, 4287-4291. (Cover feature).<br />
4. “Alkylated carborane anions <strong>and</strong> radicals,” King, B. T.; Zharov, I.; Michl, J. <strong>Chemical</strong> Innovation<br />
2001, 31, 23-29.<br />
5. “Preparation of [ closo-CB H ] 11 12 - by dichlorocarbene insertion into [nido-B H ] 11 14 - ,” Franken, A.;<br />
King, B.T.; Rudolph, J.; Rao, P.; Noll, B.C.; Michl, J. Collection of Czechoslovak <strong>Chemical</strong> Communications<br />
2001, 66, 1238-1249.<br />
6. “LiCB11Me<br />
: A catalyst for pericyclic rearrangements,” Moss, S.; King, B.T.; de Meijere, A.;<br />
12<br />
Kozhushkov, S.I.; Eaton, P.E.; Michl, J. Organic Letters 2001, 3, 2375-2377.<br />
7. “The explosive ‘inert’ anion,CB11<br />
(CF3 ) 8.<br />
- ,” King, B.T.; Michl, J. J. Am. Chem. Soc. 2000, 122, 10255.<br />
12<br />
“Crystal structure of n-Bu Sn 3 + -, CB Me ” Zharov, I.; King, B.T.; Havlas, Z.; Pardi, A.; Michl, J. J. Am.<br />
11 12<br />
Chem. Soc. 2000, 122, 10253-10254.<br />
9.<br />
+ - “Cation-π interactions in the solid state: Crystal structures of M (benzene)2CB Me (M = Tl,<br />
11 12<br />
Cs, Rb, K, Na) <strong>and</strong> Li + - (toluene)CB Me ,” King, B.T.; Noll, B.C.; Michl, J. Collection of Czechoslo-<br />
11 12<br />
vak <strong>Chemical</strong> Communications 1999, 64, 1001-1012.
DAVID M. LEITNER<br />
Associate Professor<br />
Theoretical <strong>and</strong> Biophysical <strong>Chemistry</strong>; <strong>Chemical</strong> <strong>Physics</strong><br />
E-mail: dml@unr.edu<br />
B.S. (1985), Cornell University; Ph.D. (1989), The<br />
University of Chicago (R.S. Berry); Postdoctoral (1990),<br />
25 - Faculty<br />
Brown University (J.D. Doll); NSF Postdoctoral Fellow<br />
(1991-1993); Alex<strong>and</strong>er von Humboldt Fellow (1993-<br />
94), Universität Heidelberg (L.S. Cederbaum); Research<br />
Associate (1994-98), University of Illinois at Urbana-<br />
Champaign (P.G. Wolynes); Assistant Project Scientist<br />
(1998-2000), UC San Diego.<br />
How energy flows within a molecule mediates the rate at which it reacts<br />
both in gas <strong>and</strong> condensed phases. We are developing theories describing<br />
quantum mechanical energy flow in molecules, <strong>and</strong> applying them to<br />
predict rates of conformational change, such as the prototypical chair-boat<br />
isomerization of cyclohexane, as well as photoisomerization of stilbene, a reaction<br />
that in many ways serves as a prototype for the initial event in vision.<br />
We are also exploring how energy flows in rather large molecules, on the<br />
mesoscopic scale, such as proteins or crystalline nanostructures. An underst<strong>and</strong>ing<br />
of how these objects conduct heat is valuable for emerging nanotechnologies, in<br />
addition to describing the role of heat flow during chemical reactions in mesoscopic environments.<br />
Rate theories developed for chemical reactions can also be usefully applied to describe the<br />
mobility of proteins in<br />
cells. We are examining<br />
models for transport<br />
of proteins in the<br />
membranes of cells,<br />
such as receptors or<br />
channels, that account<br />
for dynamical barriers<br />
to transport. In the<br />
red blood cell, for<br />
example, fluctuations<br />
in the structure of the<br />
membrane skeleton, largely responsible for the red blood cell’s remarkable elasticity, strongly<br />
influences the mobility of proteins spanning the red blood cell membrane.<br />
Selected Publications<br />
1. “Energy flow in proteins,” Leitner, D.M. Ann. Rev. Phys. Chem. 2008, 59, in press.<br />
2. “Quantum energy flow <strong>and</strong> the kinetics of water shuttling between hydrogen bonding<br />
sites on trans-formanilide,” Agbo, J.K.; Leitner, D.M.; Myshakin, E.M.; Jordan, K.D. J. Chem. Phys.<br />
2007, 127, art. 064315, pp. 1-10.<br />
3. “Biomolecule large amplitude motion <strong>and</strong> solvation dynamics: Modeling <strong>and</strong> probes<br />
from THz to X-rays,” Leitner, D.M.; Havenith, M.; Gruebele, M. Int. Rev. Phys. Chem. 2006, 25,<br />
553-582.<br />
4. “Thermal conductivity computed for vitreous silica <strong>and</strong> methyl-doped silica above the<br />
plateau,” Yu, X.; Leitner, D.M. Phys. Rev. B 2006, 74, art. 184305, pp. 1-11.<br />
5. “Influence of vibrational energy flow on isomerization of flexible molecules: Incorporating<br />
non-RRKM kinetics in the simulation of dipeptide isomerization,” Agbo, J.K.; Leitner, D.M.;<br />
Evans, D.A.; Wales, D.J. J. Chem. Phys. 2005, 123, 1-8.<br />
6. “Thermal transport coefficients for liquid <strong>and</strong> glassy water computed from a harmonic<br />
aqueous glass,” Yu, X.; Leitner, D.M. J. Chem. Phys. 2005, 123, art. no. 104503, pp. 1-10.<br />
7. “Heat flow in proteins: Computation of thermal transport coefficients,” Yu, X.; Leitner, D.M. J.<br />
Chem. Phys. 2005, 122, art. no. 054902, pp. 1-11.
DAVID A. LIGHTNER<br />
R.C. Fuson Professor<br />
Organic <strong>and</strong> Bioorganic <strong>Chemistry</strong><br />
E-mail: lightner@scs.unr.edu<br />
26 - Faculty<br />
A.B. (1960), University of California at Berkeley;<br />
Ph.D. (1963), Stanford University (C. Djerassi); NSF<br />
Postdoctoral Fellow (1963-64), Stanford University<br />
(C. Djerassi) <strong>and</strong> (1964-65), University of Minnesota<br />
(A. Moscowitz); Foundation Professor, University of<br />
Nevada, Reno (1987-90).<br />
Current research is directed toward synthesis, stereochemistry, molecular recognition<br />
<strong>and</strong> photochemistry, with an emphasis on (i) dipyrrole <strong>and</strong> tetrapyrrole<br />
synthetic analogs of bilirubin, the yellow pigment of jaundice; (ii) organic<br />
conformational analysis from circular dichroism <strong>and</strong> NMR spectroscopy; (iii)<br />
photobiology, molecular mechanisms of phototherapy for neonatal jaundice,<br />
bilirubin metabolism,<br />
pyrrole chemistry<br />
<strong>and</strong> photochemistry,<br />
photooxidation <strong>and</strong><br />
singlet oxygen; (iv) chiral molecular recognition;<br />
(v) chiroptical properties <strong>and</strong><br />
electronic interaction of non-adjacent<br />
chromophores, long-range interactions;<br />
(vi) exciton interactions in organic <strong>and</strong><br />
biological systems as detected by circular<br />
dichroism; <strong>and</strong> (vii) stereochemistry<br />
of cyclic ketones <strong>and</strong> the Octant Rule.<br />
Selected Publications<br />
1. “Amphiphilic dipyrrinones,” Dey, S.K.; Lightner, D.A. Monatsh. Chem. 2007, 138, 687-697.<br />
2. “Converting 9-methyldipyrrinones to 9-H <strong>and</strong> 9-CHO dipyrrinones,” Boiadjiev, S.E.; Lightner,<br />
D.A. Tetrahedron 2007, 63, 8962-8976.<br />
3. “Influence of conformation on intramolecular hydrogen bonding on the acyl glucuronidation<br />
<strong>and</strong> biliary excretion of acetylenic bis-dipyrrinones related to bilirubin,” McDonagh, A.F.;<br />
Lightner, D.A. J. Med. Chem. 2007, 50, 480-488.<br />
4. “Synthesis <strong>and</strong> hepatic metabolism of xanthobilirubinic acid regioisomers,” Boiadjiev,<br />
S.E.; Conley, B.A.; Brower, J.O.; McDonagh, A.F.; Lightner, D.A. Monatsh. Chem. 2006, 137,<br />
1463-1476.<br />
5. “Carboxylic acid to amide hydrogen bonding. Oxo-semirubins,” Salzameda, N.T.; Huggins,<br />
M.T.; Lightner, D.A. Tetrahedron 2006, 62, 8610-8619.<br />
6. “Synthesis, properties, <strong>and</strong> hepatic metabolism of strongly fluorescent fluorodipyrrinones,”<br />
Boiadjiev, S.E.; Woydziak, Z.R.; McDonagh, A.F.; Lightner, D.A. Tetrahedron 2006, 62,<br />
7043-7055.<br />
7. “Exciton chirality: (A) Origins of <strong>and</strong> (B) Applications from strongly-fluorescent dipyrrinone<br />
chromophores,” Boiadjiev, S.E.; Lightner, D.A. Monatsh. Chem. 2005, 136, 489-508.<br />
8. “Synthesis <strong>and</strong> hepatic transport of strongly fluorescent cholephilic dipyrrinones,” Woydziak,<br />
Z.R.; Boiadjiev, S.E.; Norona, W.S.; McDonagh, A.F.; Lightner, D.A. J. Org. Chem. 2005, 70,<br />
8417-8423.<br />
9. “pKa <strong>and</strong> aggregation of bilirubin: Titrimetric <strong>and</strong> ultracentrifugation studies on water-soluble<br />
pegylated conjugates of bilirubin <strong>and</strong> fatty acids,” Boiadjiev, S.E.; Watters, K.; Lai, B.; Wolf,<br />
S.; Welch, W.; McDonagh, A.F.; Lightner, D.A. Biochemistry 2004, 43, 15617-15632.<br />
10. “The gem-dimethyl effect: Amphiphilic bilirubins,” Tu, B.; Ghosh, B.; Lightner, D.A. Tetrahedron<br />
2004, 60, 9017-9029.
JASON SHEARER<br />
Assistant Professor<br />
Inorganic, Bioinorganic, <strong>and</strong> Bioorganic <strong>Chemistry</strong><br />
E-mail: shearer@unr.edu<br />
27 - Faculty<br />
B.S. (1998), University of Maryl<strong>and</strong>, College Park;<br />
Ph.D. (2001), University of Washington (J.A. Kovacs);<br />
NIH Postdoctoral Fellow (2002-04), Johns Hopkins<br />
University (K.D. Karlin)<br />
Many of life’s most important processes are performed by metalloproteins.<br />
Metalloproteins are proteins that contain one or more metal cofactors at<br />
their active-sites, <strong>and</strong> can be thought of as the ultimate transition metal<br />
complex. The lig<strong>and</strong> environment about the metal-center in a metalloprotein<br />
is often characterized by low symmetry, an unusual coordination<br />
geometry, <strong>and</strong> unique metal-lig<strong>and</strong> bonding. Therefore, many of the fine<br />
details concerning how interactions between the primary <strong>and</strong> secondary<br />
coordination sphere <strong>and</strong> the metal ion contribute to the metalloproteins<br />
physical properties <strong>and</strong> function in many metalloproteins remain unclear.<br />
To underst<strong>and</strong> these complex <strong>and</strong> fascinating systems the Shearer group utilizes a multi-tiered<br />
approach. We first start by considering the relevant information concerning the metalloprotein<br />
in question <strong>and</strong> design <strong>and</strong><br />
prepare small transition metal<br />
complexes <strong>and</strong> metallopeptides<br />
based on the active-site of the<br />
metalloprotein. These metalloprotein<br />
synthetic analogues<br />
are then subjected to a detailed<br />
spectroscopic <strong>and</strong> computational<br />
analysis. Finally the information<br />
acquired from these<br />
studies are applied back to the<br />
metalloprotein. Further studies<br />
on the metalloprotein then aid<br />
in refining future generations<br />
of the synthetic analogues, <strong>and</strong><br />
the whole process is repeated.<br />
Current areas of focus in the<br />
Shearer group concern: the<br />
biological chemistry of nickel containing metalloproteins, the interaction between copper ions<br />
<strong>and</strong> proteins involved in neurodegenerative disorders, <strong>and</strong> the biological chemistry of sulfur<br />
<strong>and</strong> selenium containing proteins.<br />
Selected Publications<br />
1. “The Cu(II) adduct of the unstructured region of the amyloidogenic fragment derived from<br />
the human prion protein is redox active at physiological pH,” Shearer, J.; Soh, P. Inorg. Chem.<br />
2007, 46, 710-719.<br />
2. “The influence of amine/amide vs. bis-amide coordination in nickel superoxide dismutase,”<br />
Neupane, K.P.; Shearer, J. Inorg. Chem. 2006, 45, 10552-10566.<br />
3. “[Me4N](NiII<br />
(BEAAM)): A synthetic model for nickel superoxide dismutase that contains Ni in<br />
a mixed amine/amide coordination environment,” Shearer, J.; Zhao, N. Inorg. Chem. 2006,<br />
45, 9637-9639.<br />
4. “A nickel superoxide dismutase maquette that reproduces the spectroscopic <strong>and</strong> functional<br />
properties of the metalloenzyme,” Shearer, J.; Long, L.M. Inorg. Chem. 2006, 45, 2358-2360.
ROBERT S. SHERIDAN<br />
Professor<br />
Organic <strong>Chemistry</strong><br />
E-mail: rss@unr.edu<br />
28 - Faculty<br />
B.S. (1974), Iowa State University; Ph.D. (1979),<br />
University of California, Los Angeles (O.L. Chapman), NSF<br />
Predoctoral Fellow; NIH Postdoctoral Fellow (1979-80),<br />
Yale University (J.A. Berson); Foundation Professor,<br />
University of Nevada, Reno (2001-03).<br />
Our research revolves around highly reactive organic molecules. These<br />
unstable <strong>and</strong> elusive intermediates, such as carbenes, nitrenes, <strong>and</strong> biradicals,<br />
are especially important in photochemistry, but their chemistry <strong>and</strong><br />
properties are poorly understood. Moreover, these molecules are related<br />
to searches for organic conducting <strong>and</strong> magnetic materials. Much of the<br />
organic synthesis that we carry out involves making previously unknown<br />
compounds, <strong>and</strong> we spend a considerable amount of our time developing<br />
new synthetic methods to tackle these challenging molecules. A specialized<br />
technique that we use to study<br />
reaction intermediates involves matrix isolation<br />
photochemistry. In this method, organic molecules<br />
are frozen into glasses of inert gas at extremely<br />
low temperatures (10 K). The samples are<br />
then irradiated with UV light to generate highly<br />
reactive intermediates. The low temperatures<br />
<strong>and</strong> high dilution in inert surroundings protect<br />
these otherwise unstable species from reaction.<br />
IR <strong>and</strong> UV spectra of the samples, acquired at low<br />
temperature, tell us a great deal about the bonding<br />
<strong>and</strong> structures of the products. Finally, we<br />
carry out a variety of ab initio <strong>and</strong> DFT electronic<br />
structure calculations to model the structures,<br />
spectra, <strong>and</strong> electronics of these novel molecules.<br />
Our recent work has focused on three major<br />
areas: (1) investigations of carbenes important<br />
in biological photoaffinity labeling, (2) highly strained organic molecules, <strong>and</strong> (3) quantum<br />
mechanical tunneling in reactive intermediates.<br />
Selected Publications<br />
1. “Quantum mechanical tunneling in organic reactive intermediates,” Sheridan, R.S., in Reviews<br />
in Reactive Intermediate <strong>Chemistry</strong>, R.A. Moss, M.S. Platz, <strong>and</strong> M.J. Jones, Jr., Ed., John Wiley &<br />
Sons, 2007, pp 415 – 463.<br />
2. “A singlet aryl-CF carbene: 2-Benzothienyl(trifluoromethyl)carbene <strong>and</strong> interconversion<br />
3<br />
with a strained cyclic allene,” Wang, J.; Sheridan, R.S. Org. Lett. 2007, 9, 3177 – 3180.<br />
3. “Conformational product control in the low-temperature photochemistry of cyclopropylcarbenes,”<br />
Zuev, P.S.; Sheridan, R.S.; Sauers, R.R.; Moss, R.A.; Chu, G. Org. Lett. 2006, 8, 4963.<br />
4. “Kinetic studies of the cyclization of singlet vinylchlorocarbenes,” Moss, R.A.; Tian, J.; Sauers,<br />
R.R.; Sheridan, R.S.; Bhakta, A.; Zuev, P.S. Org. Lett. 2005, 7, 4645.<br />
5. “Geometry <strong>and</strong> aromaticity in highly strained heterocyclic allenes: Characterization of a<br />
2,3-didehydro-2H-thiopyran,” Nikitina, A.; Sheridan, R.S. Org. Lett. 2005, 7, 4467.<br />
6. “Activation energies for the 1,2-carbon migration of ring-fused cyclopropylchlorocarbenes,”<br />
Chu, G.; Moss, R.A.; Sauers, R.R.; Sheridan, R.S.; Zuev, P.S. Tetrahedron Lett. 2005, 46, 4137.<br />
7. “Singlet Vinylcarbenes: Spectroscopy <strong>and</strong> Photochemistry,” Zuev, P. S.; Sheridan, R. S. J. Am.<br />
Chem. Soc. 2004, 126, 12220.
SUK-WAH TAM-CHANG<br />
Professor<br />
Organic <strong>and</strong> Materials <strong>Chemistry</strong>; Biosensors<br />
E-mail: tchang@unr.edu<br />
29 - Faculty<br />
B.S. (1983), University of Hong Kong, Hong Kong;<br />
Ph.D. (1992), University of California, Los Angeles (F.<br />
Diederich); Postdoctoral Fellow (1992-93) <strong>and</strong> NIH<br />
Postdoctoral Fellow (1994), Harvard University (G.M.<br />
Whitesides).<br />
An important goal of our research is to increase our basic knowledge of the<br />
relationships between molecular structure, supramolecular interactions,<br />
phase behavior, molecular orientation, <strong>and</strong> physical properties of organic<br />
compounds in the liquid-crystalline state <strong>and</strong> in the solid state. We are<br />
particularly interested in the synthesis <strong>and</strong> studies of liquid-crystalline compounds<br />
that exhibit dichroic properties (direction-dependent absorption<br />
of light) <strong>and</strong> fluorescence emission at long wavelengths. Dichroic dyes <strong>and</strong><br />
fluorophores can potentially be used as sensing probes in biological studies<br />
<strong>and</strong> as polarizing materials in liquid-crystal displays (LCDs). In addition, long<br />
wavelength absorbing materials can potentially be used in optical applications in conjunction<br />
with commercially available AlGaAs lasers that emit at 780 nm. Near-infrared (NIR) absorbing<br />
<strong>and</strong> emitting dyes have potential use in high-technology applications such as optical recording,<br />
thermally-written displays, laser printers, laser filters, infrared photography, <strong>and</strong> fiber-optic<br />
communications.<br />
Micro- <strong>and</strong> nano-patterned organic semiconducting materials have potential applications<br />
in the field of microelectronics, where the direction-dependent orientation of the molecules in<br />
these materials can enhance their semiconducting properties. In addition, patterned anisotropic<br />
(direction-dependent) materials have potential applications as angle-dependent optical<br />
materials, holographic films, <strong>and</strong> in stereoscopic displays. These organic materials may also<br />
have useful photonic <strong>and</strong> optoelectronic properties. A wide range of methods is available for<br />
the micro- <strong>and</strong> nano-patterning of isotropic (direction-independent) materials including scanning<br />
probe techniques, electron-beam lithography, photolithography, <strong>and</strong> soft-lithography.<br />
However, techniques for the micro-fabrication of anisotropic organic materials is presently<br />
limited to approaches that employ either uniaxially stretched polymer films or photo-alignment<br />
techniques. Our research group is interested in the micro- <strong>and</strong> nano-fabrication of anisotropic<br />
organic materials by template-guided organization of chromonic liquid crystals.<br />
Biosensors are devices interfaced with biological detector molecules for identifying specific<br />
target analytes. Biosensors have applications that range from medical diagnostics to environmental<br />
analysis. Our current interest focuses on the research <strong>and</strong> development of biosensors<br />
for detecting unlabeled nucleic acids.<br />
Selected Publications<br />
1. “Microfabrication of anisotropic organic materials via self-organization of an ionic perylenemonoimide,”<br />
Huang, L.; Tam-Chang, S.-W.; Seo, W.; Rove, K. Adv. Mater. 2007 [Communication]<br />
(Accepted).<br />
2. “Stem-loop probe with universal reporter for sensing unlabeled nucleic acids,” Tam-Chang,<br />
S.-W.; Carson, T.D.; Huang, L.; Publicover, N.G.; Hunter, K.W., Jr. Anal. Biochem. 2007, 326,<br />
126-130.<br />
3. “Anisotropic fluorescent materials via self-organization of perylenedicarboximide,” Huang, L.;<br />
Catalano, V.J.; Tam-Chang, S.-W. Chem. Commun. 2007, 2016-2018. [Communication]<br />
4. “Template-guided organization of chromonic liquid crystals into micropatterned anisotropic<br />
organic solids,” Tam-Chang, S.-W.; Helbley, J.; Carson, T.D.; Seo, W.; Iverson, I.K. Chem.<br />
Commun. 2006, 503-505. [Communication]
SARAH A. CUMMINGS<br />
Lecturer <strong>and</strong> Organic <strong>Chemistry</strong><br />
Coordinator<br />
<strong>Chemical</strong> Education<br />
E-mail: sac@unr.edu<br />
B.S. (2001), Haverford College; Ph.D.<br />
(2006), Columbia University (J.R. Norton); Postdoctoral<br />
(2006-2007), University of Utah (M.S. Sigman).<br />
Dr. Cummings is involved in developing <strong>and</strong><br />
upgrading the Organic <strong>Chemistry</strong> Laboratory<br />
program, <strong>and</strong> in the supervision <strong>and</strong> training<br />
of laboratory teaching assistants. In addition<br />
to overseeing the laboratory program, she<br />
also teaches General <strong>Chemistry</strong> <strong>and</strong> Organic<br />
<strong>Chemistry</strong>.<br />
Selected Publications<br />
1. “An estimate of the reduction potential of<br />
B(C F ) from electrochemical measurements on<br />
6 5 3<br />
related mesityl boranes,” Cummings, S.A.; Iimura,<br />
M.; Harlan, C.J.; Kwaan, R.J.; vu Trieu, I.; Norton,<br />
J.R.; Bridgewater, B.M.; Jakle, F.; Sundararaman, A.;<br />
Tilset, M. Organometallics 2006, 1595-1598.<br />
2 2. “Formation of a dynamic η (O,N)hydroxylaminato<br />
zirconocene complex by<br />
Nitrosoarene insertion into a ZrC σ-bond,” Cummings,<br />
S.A.; Radford, R.; Erker, G.; Kehr, G.; Fröhlich,<br />
R. Organometallics 2006, 839-842.<br />
GARRY N. FICKES<br />
Distinguished Research Professor<br />
Organic <strong>Chemistry</strong><br />
E-mail: fickes@unr.edu<br />
B.S. (1960), University of California<br />
at Davis; Ph. D. (1965), University<br />
of Wisconsin (H.L. Goering); Postdoctoral (1965-66)<br />
Harvard University (P.D. Bartlett).<br />
My research interests are in organic synthesis<br />
<strong>and</strong> reaction mechanisms. Recent synthetic<br />
work is in the areas of polycyclic ring systems,<br />
polymers with special optical properties, <strong>and</strong><br />
photochemically reactive chiral compounds.<br />
Selected Publications<br />
1. “Synthesis of soluble, substituted silane high<br />
polymers by Wurtz coupling techniques,” Miller,<br />
R.D.; Fickes, G.N.; Thompson, D.T. J. Polym. Sci.,<br />
Polym. Chem. Ed. 1991, 29, 813.<br />
2. “Block interrupt polysilane derivatives,” Miller, R.D.;<br />
Fickes, G.N. J. Polym. Sci., Polym. Chem. Ed. 1990,<br />
28, 1397.<br />
SÉSI M. MCCULLOUGH<br />
Lecturer <strong>and</strong> General <strong>Chemistry</strong><br />
Coordinator<br />
<strong>Chemical</strong> Education<br />
E-mail: smm@unr.edu<br />
B.A. (1986), California State<br />
University, Sacramento; Ph.D. (1992), University of<br />
California, Davis (C. Lebrilla); Postdoctoral (1992-<br />
1993), Beckman Research Institute, Duarte, California<br />
(T. Lee).<br />
Dr. McCullough is involved in developing <strong>and</strong><br />
upgrading the General <strong>Chemistry</strong> Laboratory<br />
program, <strong>and</strong> in the supervision <strong>and</strong> training<br />
of laboratory teaching assistants. In addition<br />
to overseeing the laboratory program, she<br />
also teaches General <strong>Chemistry</strong> <strong>and</strong> Analytical<br />
<strong>Chemistry</strong>.<br />
CHARLES B. ROSE<br />
Associate Professor<br />
Organic <strong>Chemistry</strong><br />
E-mail: crose@unr.edu<br />
B.S. (1960), Brigham Young University;<br />
M.A. (1963), Ph.D. (1966),<br />
Harvard University (R.B. Woodward); Postdoctoral<br />
Fellow (1966), Harvard University (R.B. Woodward).<br />
Current projects include synthesis <strong>and</strong><br />
determination of physical properties of the<br />
macrocyclic tetrapyrrole salts of the tetrabenzoporphyrin<br />
system. We are also studying the<br />
isolation <strong>and</strong> structure elucidation of natural<br />
products from marine sources.<br />
32 - Lecturers, Distinguished, <strong>and</strong> Emeritus Faculty
Selected Publications<br />
1. “New polychlorinated amino acid derivatives<br />
from the marine sponge Dysidea herbacea,”<br />
Unson, M.D.; Rose, C.B.; Faulkner, D.J.; Brinen,<br />
L.S.; Steiner, J.R.; Clardy, J. J. Org. Chem. 1993, 58,<br />
6336.<br />
2. “5-epi-Ilimiquinone, a metabolite of the sponge<br />
Fenestraspongia Sp.,” Carté, B.; Rose, C.B.;<br />
Faulkner, D.J. J. Org. Chem. 1985, 50, 2785.<br />
SCOTT W. WAITE<br />
Administrative Faculty<br />
Director of Laboratories<br />
E-mail: waites@unr.edu<br />
B.S. (1988), University of Arizona;<br />
Ph.D. (1993), University of Utah (J.<br />
Harris); Procter <strong>and</strong> Gamble (1993-1998); Huntsman<br />
Corporation (1998-2003); MPR Services (2003-2005).<br />
Dr. Waite teaches courses in analytical chemistry<br />
<strong>and</strong> is responsible for the general physical<br />
facilities of the chemistry department including<br />
planning <strong>and</strong> operation of facilities, financial<br />
planning <strong>and</strong> budgeting, planning <strong>and</strong><br />
coordination of renovation <strong>and</strong> maintenance<br />
of facilities, <strong>and</strong> long range planning of space<br />
needs. He prepares the class schedules for<br />
instructional <strong>and</strong> laboratory programs including<br />
the AP chemistry laboratory program. He<br />
is the Departmental Safety Officer responsible<br />
for the administration of the <strong>Chemical</strong><br />
Hygiene Plan, Hazardous Materials Disposal<br />
Program, the Emergency Response Plan, <strong>and</strong><br />
the Student Safety Policy, <strong>and</strong> he serves as the<br />
Departmental Emergency Coordinator. Dr.<br />
Waite also supervises the classified technical<br />
staff <strong>and</strong> stockroom supervisors.<br />
Selected Publications<br />
1. “Assessment of alcohol ethoxylate surfactants<br />
<strong>and</strong> fatty alcohol mixtures in river sediments<br />
<strong>and</strong> prospective risk assessment,” Dyer, S.D.;<br />
S<strong>and</strong>erson, H.; Waite, S.W.; Van Compernolle, R.;<br />
Price, B.; Nielsen, A.M.; Evans, A.; Decarvalho, A.J.;<br />
Hooton, D.J; Sherren, A.J. Environ. Monit. Assess.<br />
2006, 120, 45.<br />
2. “Occurrence <strong>and</strong> hazard screening of alkyl sulfates<br />
<strong>and</strong> alkyl ethoxysulfates in river sediments,”<br />
S<strong>and</strong>erson, H.; Price, B.B.; Dyer, S.D.; DeCarvalho,<br />
A.J.; Robaugh, D.; Waite, S.W.; Morrall, S.W.;<br />
Nielsen, A.M.; Cano, M.L.; Evans, K.A. Sci. Tot. Env.<br />
2006, 367, 312.<br />
3. “Corrosion <strong>and</strong> corrosion enhancers in amine<br />
systems,” Cummings, A.L.; Waite, S.W.; Nelson, D.K.<br />
Proceedings of the Brimstone Sulfur Conference,<br />
Banff, Alberta, 2005.<br />
33 - Lecturers, Distinguished, <strong>and</strong> Emeritus Faculty<br />
RICHARD D. BURKHART<br />
Professor Emeritus<br />
Physical <strong>Chemistry</strong>; <strong>Chemical</strong><br />
<strong>Physics</strong><br />
A.B. (1956), Dartmouth College;<br />
Ph.D. (1960), University of Colorado.<br />
Our research is centered upon photophysical<br />
processes involving pure <strong>and</strong> molecularly<br />
doped polymers. Since polymers are<br />
potentially useful materials for optoelectronic<br />
devices or solar energy applications, characterization<br />
of their light-induced properties<br />
is of considerable interest both in the solid<br />
state <strong>and</strong> in solution. We use high powered<br />
excimer lasers or tunable dye lasers as the<br />
excitation source <strong>and</strong> luminescence spectra<br />
are recorded using diode arrays.<br />
Selected Publications<br />
1. “Some photophysical properties of electronically<br />
excited phenldibenzophosphole in rigid<br />
polymer matrices,” Ganguly, T.; Burkhart, R.D. J.<br />
Phys. Chem. A 1997, 101, 5633-5639.<br />
2. “Triplet energy migration in poly(4-methacryloylbenzophenone-co-methyl<br />
methacrylate) films:<br />
Temperature dependence <strong>and</strong> chromophore<br />
concentration dependence,” Tsuchida, A.; Yamamoto,<br />
M.; Liebe, W.R.; Burkhart, R.D.; Tsubakiyama,<br />
K. Macromolecules 1996, 29, 1589-1594.
KENNETH C. KEMP<br />
Professor Emeritus<br />
Organic <strong>Chemistry</strong><br />
E-mail: kempistry@aol.com<br />
B.S. (1950), Northwestern University;<br />
Ph.D. (1956), Illinois Institute of<br />
Technology (M.L. Bender).<br />
The effects of neighboring groups on reactions<br />
of derivatives of carboxylic acids are<br />
of interest. Examples include accelerating<br />
effects of the carbonyl group in the alkaline<br />
hydrolysis of gamma-keto esters <strong>and</strong> of the<br />
carboxylate group in the solvolysis of gammabromophenylacetates.<br />
The scope <strong>and</strong><br />
sythetic utility of intramolecular Friedel-Crafts<br />
acylation of alkenes are also of interest. By<br />
studying the structure <strong>and</strong> stereochemistry of<br />
the cyclization products from acid chlorides, it<br />
is hoped that a clearer insight into the nature<br />
of the reaction will emerge.<br />
Selected Publications<br />
1. “A novel, simple, <strong>and</strong> inexpensive model for<br />
teaching VSEPR theory,” Kemp, K.C. J. Chem. Educ.<br />
1988, 65, 222.<br />
2. “Writing chemical equations. Introductory<br />
experiment,” LeMay, H.E., Jr.; Kemp, K.C. J. Chem.<br />
Educ. 1975, 52, 121<br />
H. EUGENE LEMAY, JR.<br />
Professor Emeritus<br />
Inorganic <strong>Chemistry</strong>; <strong>Chemical</strong><br />
Education<br />
E-mail: lemay@unr.edu<br />
B.S. (1962), Pacific Lutheran University;<br />
M.S. (1964), Ph.D. (1966), University of Illinois<br />
(J.C. Bailar).<br />
I am greatly interested in chemical education<br />
<strong>and</strong> are involved in textbook development<br />
both as a author <strong>and</strong> as a consultant. Two<br />
textbooks that I have coauthored are widely<br />
used in college <strong>and</strong> high school courses:<br />
<strong>Chemistry</strong>: the Central Science, a gen-<br />
eral chemistry textbook that is also used in<br />
advanced-placement courses in high schools,<br />
<strong>and</strong> <strong>Chemistry</strong>: Connections to our Changing<br />
World, a high-school text.<br />
Selected Publications<br />
1. <strong>Chemistry</strong>: The Central Science,<br />
9th ed., Theodore<br />
L. Brown, H. Eugene LeMay, Jr., Bruce E. Bursten,<br />
<strong>and</strong> Julia R. Burdge (Prentice Hall, Englewood<br />
Cliffs, NJ, 2003).<br />
2. <strong>Chemistry</strong>: Connections to Our Changing World, H.<br />
Eugene LeMay, Jr., Herbert Beall, Karen M. Robblee,<br />
<strong>and</strong> Douglas C. Brower (Prentice Hall, Upper<br />
Saddle River, NJ, 1996).<br />
3. “Solid-phase thermal isomerization of<br />
dicarbonyldichlorobis(tertiary phosphine)<br />
ruthenium <strong>and</strong> carbonyldichlorotris(tertiary<br />
phosphine)ruthenium complexes,” Krassowski,<br />
D.W.; Reimer, K.; LeMay, H.E., Jr.; Nelson, J.H. Inorg.<br />
Chem. 1988, 27, 4307-9.<br />
JOHN H. NELSON<br />
Professor Emeritus<br />
Inorganic <strong>Chemistry</strong><br />
E-mail: jhnelson@unr.edu<br />
B.S. (1964), Ph.D. (1968), University<br />
of Utah (R.O. Ragsdale); Postdoctoral<br />
(1968-70), Tulane University (H.B. Jonassen).<br />
Research interests include the synthesis,<br />
physical properties, structure, reactions <strong>and</strong><br />
catalytic properties of coordination <strong>and</strong><br />
organometallic compounds. We have been<br />
pursuing four avenues of research: (1) Structure,<br />
dynamics, <strong>and</strong> bonding in Pd(II) <strong>and</strong><br />
Pt(II) complexes. (2) Reactions of coordinated<br />
lig<strong>and</strong>s, particularly phosphines <strong>and</strong> arsines.<br />
(3) Solid state NMR spectroscopy. (4) Asymmetric<br />
homogeneous catalysis.<br />
Selected Publications<br />
1. “Phosphaallyl complexes of Ru(II) derived from<br />
dicyclohexylvinylphosphine (DCVP),” Duraczynska,<br />
D.; Nelson, J.H. Dalton Trans. 2005, 92-103.<br />
2.<br />
“Reactions of ruthenium(II) tris(pyrazolyl)borate<br />
34 - Lecturers, Distinguished, <strong>and</strong> Emeritus Faculty
<strong>and</strong> tris(pyrazolyl)methane complexes with<br />
diphenylvinylphosphine <strong>and</strong> 3,4-dimethyl-1phenylphosphole,”<br />
Wilson, D.C.; Nelson, J.H. J.<br />
Organomet. Chem. 2003, 682, 272-289.<br />
HYUNG K. SHIN<br />
Professor Emeritus<br />
Theoretical <strong>Chemistry</strong>; <strong>Chemical</strong><br />
<strong>Physics</strong><br />
E-mail: shin@unr.nevada.edu<br />
B.S. (1959), Ph. D. (1961), University<br />
of Utah (J.C. Giddings); Postdoctoral (1963-64),<br />
Cornell University (B. Widom, P. Debye).<br />
Research activities center around the theory<br />
of molecular collisions. Principal topics of<br />
current research include the dynamics of gassurface<br />
reactions, collision-induced intramolecular<br />
energy flow <strong>and</strong> bond dissociation in<br />
large molecules, <strong>and</strong> vibrational relaxation of<br />
matrix-isolated guest molecules.<br />
Selected Publications<br />
1. “Host-assisted intramolecular vibrational relaxation<br />
at low temperatures: OH in an argon cage,”<br />
Shin, H.K. J. Chem. Phys. 2006, 125, 024501, pp.<br />
1-10.<br />
2. “Collision-induced dissociation of transition<br />
metal-oxide ions: Dyanmics of VO + collision<br />
with Xe,” Ree, J.; Kim, Y.H.; Shin, H.K. J. Chem. Phys.<br />
2006, 124, 074307, pp. 1-12.<br />
3. “Threshold collision-induced dissociation of diatomic<br />
molecules: A case study of the energet-<br />
- ics <strong>and</strong> dynamics of O collisions with Ar <strong>and</strong> Xe,”<br />
2<br />
Akin, F.A.; Ree, J.; Ervin, K.M.; Shin, H.K. J. Chem.<br />
Phys. 2005, 123, art. no. 064308, pp. 1-12.<br />
35 - Lecturers, Distinguished, <strong>and</strong> Emeritus Faculty
University of Nevada, Reno<br />
36<br />
Department of <strong>Chemistry</strong><br />
University of Nevada, Reno<br />
1664 North Virginia Street<br />
Reno, NV 89557-0216<br />
775-784-6041<br />
www.chem.unr.edu