Reviewers, Volume 6" (1992) - Genes & Development
Reviewers, Volume 6" (1992) - Genes & Development
Reviewers, Volume 6" (1992) - Genes & Development
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<strong>Reviewers</strong>, <strong>Volume</strong> 6" (<strong>1992</strong>)<br />
The Editors would like to thank the<br />
Editorial Board and the following<br />
scientists who were kind enough to<br />
review papers and provide advice during<br />
<strong>1992</strong>. Your help has been invaluable and<br />
is greatly appreciated.<br />
* From November 18, 1991 to November<br />
16, <strong>1992</strong><br />
Aaronson, Stuart<br />
Adler, Paul<br />
Alt, Fred<br />
Altman, Sid<br />
Ammeter, Gustav<br />
Anderson, David<br />
Anderson, Kathryn<br />
Ares, Manuel<br />
Amdt, Kim<br />
Amold, Hans<br />
Artavanis-Tsakonas, Spyros<br />
Ausubel, Fred<br />
Baeuerle, Patrick<br />
Baker, Bruce<br />
Baldwin, Albert<br />
Baltimore, David<br />
Banerjee, Utpal<br />
Barbacid, Mariano<br />
Beach, David<br />
Beddington, Rosa<br />
Beemon, Karen<br />
Beene, Michael<br />
Belfort, Marlene<br />
Bentley, David<br />
Berk, Arnold<br />
Beme, Michael<br />
Betas, Anton<br />
Bemstein, Alan<br />
Bienz, Mariann<br />
Biggin, Mark<br />
Bingham, Paul<br />
Bird, Adrian<br />
Bishop, J. Michael<br />
Bissell, Mina<br />
Blackburn, Elizabeth<br />
Boeke, Jeff<br />
Botchan, Michael<br />
Bothwell, AI<br />
Bradley, Allan<br />
Breeden, Linda<br />
Brimacombe, Richard<br />
Broach, James<br />
Brockes, Jeremy<br />
Brown, Donald<br />
Bryant, Peter<br />
Buchman, Andrew<br />
Burr, Ben<br />
Calame, Kathryn<br />
Campbell, Judith<br />
Capecchi, Mario<br />
Carey, Michael<br />
Carlson, Mary Ann<br />
2666 GENES & DEVELOPMENT<br />
Carroll, Sean<br />
Chaconas, George<br />
Chater, Keith<br />
Chesebro, Bruce<br />
Chory, Jo Anne<br />
Clayton, David<br />
Cleveland, Donald<br />
Cline, Thomas<br />
Coen, Enrico<br />
Cole, Michael<br />
Collins, Francis<br />
Corces, Victor<br />
Costantini, Frank<br />
Cox, Michael<br />
Crabtree, Gerald<br />
Craig, Elizabeth<br />
Craig, Nancy<br />
Cullen, Bryan<br />
Curran, Tom<br />
Darnell, James<br />
DePamphilis, Mel<br />
Desplan, Claude<br />
Devreotes, Peter<br />
DiMaio, Dan<br />
Doe, Chris<br />
Donahue, Tom<br />
Donovan, Peter<br />
Dunphy, William<br />
Driever, Wolfgang<br />
Dynan, Bill<br />
Efstratiadis, Argiris<br />
Ehrenfeld, Ellie<br />
Eichele, Gregor<br />
Eisenman, Bob<br />
Emerson, Charles<br />
Engel, Douglas<br />
Esposito, Rochelle<br />
Evans, Ronald<br />
Fangman, Walter<br />
Fanning, Ellen<br />
Fedoroff, Nina<br />
Felsenfeld, Gary<br />
Feramisco, Jim<br />
Fields, Stanley<br />
Fink, Gerald<br />
Firtel, Richard<br />
Foumier, Keith<br />
Freeling, Mike<br />
Friedman, David<br />
Fu, Xin-Yuan<br />
Fuchs, Elaine<br />
Futcher, Bruce<br />
Fyrberg, Eric<br />
Ganem, Don<br />
Gaynor, Richard<br />
Gehring, Walter<br />
Gelbart, William<br />
Gerandakis, Steve<br />
Gergen, Peter<br />
Gilman, Mike<br />
Glover, David<br />
Goodman, Corey<br />
Gralla, Jay<br />
Graves, Barbara<br />
Green, Michael<br />
Greenberg, Michael<br />
Greenblatt, Jack<br />
Greene, Warner<br />
Greenleaf, Amo<br />
Greider, Carol<br />
Grosschedl, Rudolf<br />
Gruss, Peter<br />
Gurdon, John<br />
Hahn, Steve<br />
Hamlin, Joyce<br />
Hanahan, Doug<br />
Harland, Richard<br />
Harlow, Edward<br />
Harper, Jeff<br />
Harrison, Steven<br />
Hartenstein, Volker<br />
Hartley, David<br />
Hayday, Adrian<br />
Hearing, Patrick<br />
Helfman, David<br />
Hemandez, Nouria<br />
Herrlich, Peter<br />
Hershey, John<br />
Herskowitz, Ira<br />
Hieter, Phil<br />
Hill, Robert<br />
Hinnebusch, Alan<br />
Hirsch, Jay<br />
Hochstrasser, Mark<br />
Hopper, Anita<br />
Hopwood, David<br />
Hovanessian, Ara<br />
Howley, Peter<br />
Huberman, Joel<br />
Hudson, Andrew<br />
Hughes, Steven<br />
Hunter, Tony<br />
Hynes, Richard<br />
Inouye, Masayori<br />
Ish-Horowicz, David<br />
Jackson, Ian<br />
Jaeckle, Herbert<br />
Jaenisch, Rudi<br />
Jan, Yuh-Nung<br />
Jessell, Thomas<br />
Johnson, Peter<br />
Johnson, Alexander<br />
Jolicoeur, Paul<br />
Jones, Katherine<br />
Joyner, Alex<br />
Kadesch, Tom<br />
Kadonaga, James<br />
Kaiser, Dale<br />
Kaiser, Kim<br />
Karin, Michael<br />
Kessin, Richard<br />
Kingston, Robert<br />
Kintner, Chris<br />
Kleckner, Nancy<br />
Klessig, Daniel<br />
Knowles, Barbara<br />
Kolodner, Richard<br />
Konieczny, Stephen
Komberg, Thomas<br />
Krainer, Adrian<br />
Kramer, Angela<br />
Krasnow, Mark<br />
Krisch, Henry<br />
Krug, Robert<br />
Krumlauff, Robb<br />
Kushner, Sydney<br />
Lamond, Angus<br />
Laskey, Ron<br />
Lassar, Andrew<br />
Leder, Philip<br />
Lehmann, Ruth<br />
Leptin, Maria<br />
Levine, Michael<br />
Levy, David<br />
Lichtenstein, Conrad<br />
Lis, John<br />
Liu, Leroy<br />
Livingston, David<br />
Lowy, Doug<br />
Lucas, William<br />
Maniatis, Tom<br />
Marlzuff, William<br />
Martienssen, Rob<br />
Mathews, Mike<br />
McClure, William<br />
McKay, Ron<br />
McKeown, Mike<br />
Melton, Doug<br />
Meyer, Barbara<br />
Meyerowitz, Elliott<br />
Mizuuchi, Kiyoshi<br />
Molloy, Peter<br />
Moran, Charles<br />
Moran, Elizabeth<br />
Morris, Ron<br />
Murray, Andrew<br />
Nabel, Gary<br />
Nadal-Ginard, Bemardo<br />
Nevins, Joseph<br />
Newman, Andrew<br />
Nomura, Masayasu<br />
Novick, Richard<br />
Nurse, Paul<br />
Nusse, Roel<br />
O'Farrell, Patrick<br />
0liver, Donald<br />
Olson, Eric<br />
Oren, Moshe<br />
Orkin, Stuart<br />
Pabo, Carl<br />
Pace, Norman<br />
Parada, Luis<br />
Perlman, Phil<br />
Posakony, James<br />
Prescott, David<br />
Preston, Chris<br />
Prives, Carol<br />
Proudfoot, Nick<br />
Ptashne, Mark<br />
Quail, Peter<br />
Racaniello, Vincent<br />
Rao, N.<br />
Rechsteiner, Martin<br />
Reed, Robin<br />
Reed, Steven<br />
Reeder, Ronald<br />
Reinberg, Daniel<br />
Renkawitz, R.<br />
Reznikoff, Bill<br />
Rheinwald, Jim<br />
Rigby, Peter<br />
Riggs, Arthur<br />
Rio, Donald<br />
Roberts, Jeff<br />
Roberts, Jim<br />
Roeder, Robert<br />
Rosbash, Michael<br />
Rose, Mark<br />
Rosen, Craig<br />
Rosenfeld, Geoff<br />
Ross, Jeff<br />
Rossant, Janet<br />
Rotter, Varda<br />
Russell, Paul<br />
Rutter, William<br />
Ruvkun, Gary<br />
Sakano, Hitoshi<br />
Sassone-Corsi, Paolo<br />
Schedl, Paul<br />
Scheres, Ben<br />
Scholer, Hans<br />
Schupbach, Trudi<br />
Segall, Jacqueline<br />
Sharp, Philip<br />
Sherr, Charles<br />
Shimkets, L.<br />
Shore, David<br />
Silhavy, Tom<br />
Silver, Lee<br />
Simon, Melvin<br />
Smale, Steven<br />
Smith, Gerald<br />
Smith, Issar<br />
Smith, Jim<br />
Sollner-Webb, Barbara<br />
Sonnenberg, Nahum<br />
Soriano, Philippe<br />
Spector, David<br />
Spiegelman, Bruce<br />
Spradling, Alan<br />
Sprague, George<br />
Stavnezer, Edward<br />
Stenlund, Ame<br />
Stemglanz, Roll<br />
Steward, Ruth<br />
Stillman, Bruce<br />
Storb, Urusla<br />
Stragier, Patrick<br />
Strickland, Sidney<br />
Struhl, Gary<br />
Struhl, Kevin<br />
Stunnenberg, H.<br />
Surani, Azim<br />
Susskind, Miriam<br />
Szostak, Jack<br />
Tatchell, Kelly<br />
Taylor, Michael<br />
Tegtmeyer, Peter<br />
Thomer, Jeremy<br />
Thummel, Carl<br />
Timberlake, William<br />
Treisman, Richard<br />
Triezenberg, Steven<br />
Tye, Bik<br />
van der Vliet, Peter<br />
Van Dyke, Terry<br />
van Montagu, Mark<br />
Vassali, Jean-Dominique<br />
Vennstrom, Bjom<br />
Verma, Inder<br />
Voellmy, Richard<br />
Vogt, Peter<br />
Wahl, Geoff<br />
Walbot, Virginia<br />
Walsh, Frank<br />
Warner, Anne<br />
Wassarman, Paul<br />
Weinberg, Robert<br />
Weiner, Alan<br />
Weintraub, Harold<br />
Weissman, Charles<br />
Wessler, Sue<br />
Westphal, Henry<br />
White, Eileen<br />
Wickens, Marvin<br />
Wieschaus, Eric<br />
Wilkinson, David<br />
Willison, Keith<br />
Winston, Fred<br />
Wolffe, Alan<br />
Wolgemuth, Deborah<br />
Woolford, John<br />
Wormington, Michael<br />
Wright, Chris<br />
Wu, Carl<br />
Yamamoto, Keith<br />
Yaniv, Moshe<br />
Yanofsky, Carl<br />
Young, Michael<br />
Young, Richard<br />
Zakian, Virginia<br />
Ziff, Edward<br />
Zipursky, Larry<br />
Zucker, Charles<br />
GENES & DEVELOPMENT 2667
Advertisers, <strong>Volume</strong> 6<br />
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American Association for Cancer<br />
Research<br />
American Association of Anatomists<br />
American Type Culture Collection<br />
Bio 101<br />
Blackwell Scientific Publications, Inc.<br />
Brinkmann Instruments, Inc.<br />
Cold Spring Harbor Laboratory<br />
Company of Biologists Limited<br />
DNA Proscan<br />
Elsevier Trends Journals<br />
Emory University School of Medicine<br />
Epicentre Technologies<br />
Europa Scientific Software Corporation<br />
Eye Research Institute of Canada<br />
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Howard Hughes Medical Institute<br />
John hines Institute<br />
Jones & Bartlett Publishers<br />
Keystone Laboratories, Inc.<br />
Keystone Symposium<br />
Kuwait Foundation for the Advancement<br />
of Sciences<br />
2668 GENES & DEVELOPMENT<br />
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Mayo Clinic Scottsdale<br />
National Cancer Institute-Frederick<br />
Cancer Research and<br />
<strong>Development</strong> Center<br />
National Scientific Supply Company, Inc.<br />
Nortech Laboratories, Inc.<br />
Oak Ridge Associated Universities, Inc.<br />
Oxford Journals<br />
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Scripps Research Institute<br />
Seikagaku America, Inc.<br />
Sigma Chemical Company<br />
Sinauer Associates, Inc.<br />
Springer-Verlag New York, Inc.<br />
Textco, Inc.<br />
The Hospital for Sick Children<br />
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The Royal Society of Medicine<br />
TIAA CREF<br />
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Tropix, Inc.<br />
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Author Index, <strong>Volume</strong> 6 (<strong>1992</strong>)<br />
Abel, T., 466<br />
Abravaya, K., 1153<br />
Adams, B., 1589<br />
Adzuma, K., 1679<br />
Atfolter, M., 1082<br />
Aguzzi, A., 1589<br />
Aizawa, S., 1821<br />
Akizawa, T., 2066<br />
Alley, M.R.K., 825<br />
Almir6n, M., 2646<br />
Alonso-Caplen, F.V., 255<br />
Alt, F.W., 61, 2248<br />
Altman, E., 1165<br />
Amberg, D.C., 1173<br />
Ammerer, G., 1280<br />
Anderson, C.W., 426<br />
Androphy, E.J., 105<br />
Ariel, M., 705<br />
Amdt, K.M., 1319<br />
Amdt, K.T., 2417<br />
Arnold, H.H., 888<br />
Auerbach, B.A., 691, 903<br />
Awedimento, E.V., 1621<br />
Baeuerle, P.A., 2352<br />
Baichwal, V.R., 1493<br />
Baker, B.S., 2569<br />
Baker, T.A., 2221<br />
Baldwin Jr., A.S., 1899<br />
Baltimore, D., 775<br />
Bang, A.G., 1752<br />
Bannister, A.I., 1810<br />
Bargonetti, J., 1143<br />
Bargonetti, 1., 1886<br />
Barker, D.D., 2312<br />
Bartelmez, S., 2258<br />
Barton, S.C., 1843<br />
Baserga, S.I., 1120<br />
Beckman, D.L., 268<br />
Bedell, M.A., 1832<br />
Beg, A.A., 1899<br />
Behrendtsen, O., 939<br />
Behrens, S.-E., 631<br />
Belasco, J.G., 135<br />
Belfort, M., 1269<br />
Bell-Pedersen, D., 2382<br />
Bellen, H.J., 2125<br />
Benezra, R., 1466<br />
Bennett, M., 1986<br />
Bentley, D.L., 1562<br />
Benusiglio, E., 1621<br />
Benvenisty, N., 2513<br />
Berberich, S.J., 166<br />
Berk, A.J., 1964<br />
Bemstein, P.L., 642<br />
Bestor, T.H., 2536<br />
Beug, H., 876<br />
Bhatt, R., 466<br />
Bier, E., 1503, 1728, 2137<br />
Biere, A.L., 2409<br />
Biggin, M.D., 1531<br />
Bird, A., 876<br />
Blackwood, E.M., 71<br />
Blundell, P.A., 14<br />
Bober, E., 888<br />
Boehmelt, G., 876<br />
Bolado, J., 578<br />
Bonapace, I.M., 1621<br />
Bonnez, W., 1131<br />
Borgmeyer, U., 329, 578<br />
Bossy-Wetzel, E., 2340<br />
Bouly, I--P., 1019<br />
Bouvet, P., 135<br />
Boyer, T.G., 1964<br />
Brandeis, M., 705<br />
Brannan, C.I., 1832<br />
Braun, T., 888<br />
Bravo, R., 2340<br />
Breitbart, R.E., 1783<br />
Brill, S.J., 1332<br />
Brock, H.W., 223<br />
Brody, E., 497<br />
Broker, T.R., 1131<br />
Brown, D., 2152<br />
Brown, P.O., 511<br />
Brown, S.A., 2288<br />
Brown, T.A., 2502<br />
Bruder, J.T., 545<br />
Brun, Y.V., 2395<br />
Brunvand, M., 2201<br />
Bulla, G.A., 316<br />
Burke, J.M., 129<br />
Busslinger, M., 1589<br />
Butler, G., 93<br />
Cairns, B.R., 1305<br />
Callahan, R., 345<br />
Campbell, S., 367<br />
Carey, M., 1716<br />
Carlson, L.L., 2536<br />
Carlson, M., 1707<br />
Carpousis, A.J., 149<br />
Carr, A.M., 2035<br />
Carroll, S., 2606<br />
Cassano, S., 1621<br />
Casselton, L.A., 568<br />
Cedar, H., 705<br />
Chadwick, R.B., 2165<br />
Chaillet, J.R., 1843<br />
Chalker, D.L., 117<br />
Chambard, J.-C., 676<br />
Chandler, V.L., 864, 2152<br />
Charron, J., 2248<br />
Chase, J.W., 2010<br />
Chasman, D.I., 296<br />
Chellappan, S.P., 177<br />
Chen, C.-H., 655, 745<br />
Chen, L., 81<br />
Cheng, J., 1444<br />
Cheng, N., 223<br />
Chiao, P., 2352<br />
Chittenden, T., 953<br />
Chovnick, A., 367<br />
Chow, A.M., 1950<br />
Chow., L.T., 1131<br />
Chu, E., 345<br />
Chua., N.-H., 2364<br />
Chuhjo, T., 2066<br />
Citron, M., 2409<br />
Clark, C.D., 2288<br />
Clayton, D.A., 1975<br />
Cleary, M.A., 2058<br />
Cleary, M.L., 1608<br />
Cleveland, D.W., 1927<br />
Clyman, 1-, 1269<br />
Cohen, B., 715<br />
Cohen, S.M., 715<br />
Colbert, T., 1940<br />
Cole, C.N., 1173<br />
Cole, M.D., 166<br />
Coleman, T.A., 745<br />
Colgan, 1., 304<br />
Collins, S.J., 2258<br />
Cone, K.C., 864<br />
Conlon, R.A., 691<br />
Cook, A., 1810<br />
Copeland, N.G., 1832<br />
Corces, V.G., 1865<br />
Cortese, R., 316<br />
Cowie, A., 481<br />
Cross, F.R., 1695<br />
Croston, G.E., 2270<br />
Cullen, B.R., 2077<br />
D'Evelyn, D., 2125<br />
Dahlberg, I.E., 1097<br />
Datum, K., 2258<br />
Dang., C.V., 81<br />
Darrow, A.L., 1202<br />
Dawid, I.B., 356<br />
de la Pompa, J.L., 14<br />
DeArmond, S.J., 1213<br />
DeCamillis, M., 223<br />
DeGregori, J.V., 919<br />
DeLoia, J.A., 1190<br />
Demeter, L.M., 1131<br />
DePinho, R.A., 1480<br />
DeRobertis, E.M., 591<br />
DeSimone, V., 316<br />
Dickinson, L.K., 2312<br />
Dickson, B., 2327<br />
Dillon, N., 1857<br />
Dirksen, M.L., 599<br />
Dohrmann, P.R., 93<br />
Dollard, S.C., 1131<br />
Donahue, T.F., 2463<br />
Donovan, P.J., 1832<br />
D6rfler, P., 1589<br />
Dorland, S., 93<br />
Dubendorff, 1., 2524<br />
Duckett, C.S., 2352<br />
Dulic, V., 1874<br />
Dunlap, J.C., 2382<br />
Dvir, A., 426<br />
Dynan, W.S., 426<br />
Eaton, S., 2635<br />
Ehretsmann, C.P., 149<br />
Eisenman, R.N., 71<br />
Eisenmann, D.M., 1319<br />
Eltman, 1., 2524<br />
Emerson, B.M., 521<br />
Emori, Y., 50, 1005<br />
Emory, S.A., 135<br />
Engel, J.D., 161, 730<br />
Enoch, T., 2035<br />
Epner, E.M., 928<br />
Eppig, J.J., 1832<br />
Epstein, C.B., 1695<br />
Errede, B., 1293<br />
Evans, R., 2258<br />
Evans, R.M., 329, 578<br />
Faha, B., 1874<br />
Falb, D., 454<br />
Fangman, W.L., 380<br />
Feder, J.H., 1402<br />
Feliciello, A., 1621<br />
Ferguson-Smith, A.C., 1843<br />
Femandez-Sarabia, M.J., 2417<br />
Firtel, R.A., 38<br />
Fisher, P., 2248<br />
Flanagan, P.M., 296<br />
Foley, K.P., 730<br />
Fong, T.C., 521<br />
Forrester, W., 1914<br />
Forrester, W.C., 928<br />
Foumier, R.E.K., 316<br />
Frank, D., 2112<br />
Franke, A., 1241<br />
Frederickson, R.M., 1631<br />
Fresco, L.D., 1386<br />
Friedel, C., 919<br />
Friedman, P.N., 1886<br />
Fuchs, E., 1444<br />
Fujii, M., 2066<br />
Fujita, T., 775<br />
Furlong, D., 2646<br />
Furukubo-Tokunaga, K., 1082<br />
Furuya, M., 2364<br />
Gallahan, D., 345<br />
Gallo, A., 1621<br />
Garbi, C., 1621<br />
Gartner, A., 1280<br />
Gaubatz, S., 568<br />
Gauss, G.H., 1553<br />
Gehring, W.J., 1030, 1082<br />
German, M.S., 2165<br />
Gershon, P.D., 1575<br />
Geyer, P.K., 1865<br />
Ghosh, S., 775<br />
Giardina, C., 2190<br />
Gillis, S., 61<br />
Gilmore-Herbert, M., 1120<br />
Glazer, L., 1668<br />
Goff, S.A., 864<br />
Goff, S.P., 2248<br />
Gold, L., 497<br />
Goldstein, A.L., 1173<br />
Gomer, R.H., 390<br />
Good, P.J., 356<br />
Gorham, B.I., 2429<br />
Gottesman, M.E., 1621<br />
G6ttgens, B., 568<br />
Gottschling, D.E., 197<br />
Grabowski, P.J., 2554<br />
Gralla, J.D., 1716<br />
Graves, B.J., 975<br />
Green, S.R., 2478<br />
Greene, I.R., 93<br />
Gregoriades, A., 568<br />
GENES & DEVELOPMENT 2669
Gross, C.A., 1165<br />
Grossman, S.R., 105<br />
Grossniklaus, U., 1030<br />
Grosveld, F., 1857<br />
Groudine, M., 928, 2201<br />
Grunstein, M., 411<br />
Gualberto, A., 815<br />
Guarente, L., 2001<br />
Gunther, C.V., 975<br />
Guo, Q., 1357<br />
Guthrie, C., 2112<br />
Habener, J.F., 439<br />
Hadwiger, J.A., 38<br />
Hafen, E., 2327<br />
Hahn, S., 1940<br />
Halfter, U., 2364<br />
Hanahan, D., 2340<br />
Handel, M.A., 1832<br />
Harm, S.R., 1229<br />
Hannah, L.C., 609<br />
Hardy, C.F.J., 801<br />
Harlow, E., 1874<br />
Haskill, S., 1899<br />
Hassell, J.A., 481<br />
Hattori, T., 609<br />
Hecker, R., 1213<br />
Heidecker, G., 545<br />
Henze, M., 2021<br />
Hermans-Borgmeyer, I., 578<br />
Herr, W., 2058<br />
Herranz, A.B., 129<br />
Herrick, D.J., 642<br />
Heyman, R., 329, 2258<br />
Hiebert, S.W., 177<br />
Higashijima, S.-i., 50, 1005<br />
Hirschhom, J.N., 2288<br />
Hoekstra, M.F., 578<br />
Hoffman, B.E., 2554<br />
Holmgren, R.A., 161<br />
Hopewell, R., 2429<br />
Hopkins, N., 1<br />
Horowitz, J.M., 177<br />
Hunger, S.P., 1608<br />
Hunter, T., 578<br />
Ikawa, Y., 1821<br />
Inamdar, M., 367<br />
Ip, Y.T., 1518, 1728<br />
Ishimaru, S., 50<br />
Isoda, K., 619<br />
Isshiki, T., 2455<br />
Iwasaki, H., 2214<br />
Izban, M.G., 1342<br />
Jackson-Grusby, L., 29<br />
Jaeger, L., 1373<br />
Jain, R., 390<br />
Jamrich, M., 356, 599<br />
Jan, L.Y., 2137<br />
Jan, Y.N., 1503, 2137<br />
Jantzen, H.-M., 1950<br />
JaramiUo, M.L., 1631<br />
Jeannotte, L., 2248<br />
Jegalian, B.G., 591<br />
Jen, Y., 1466<br />
Jendroska, K., 1213<br />
Jenkins, N.A., 1832<br />
Jhappan, C., 345<br />
2670 GENES & DEVELOPMENT<br />
Johnson, D., 1190<br />
Johnson, F.B., 2177<br />
Johnson, L., 411<br />
Jones, B.A., 380<br />
Jones, P.A., 1843<br />
Jonsen, M.D., 975<br />
Joseph, S., 129<br />
Joyner, A.L., 691,903<br />
Ju, Q., 1332<br />
Kadonaga, J.T., 1542, 2270<br />
Kaelin Jr., W.G., 953<br />
Kafri, T., 705<br />
Kageyama, R., 2620<br />
Kakizuka, A., 329, 578<br />
Kalfayan, L.J., 233<br />
Karin, M., 676<br />
Kato, G.J., 81<br />
Kato, H., 655<br />
Kay, S., 2364<br />
Kelleher III, R.J., 296<br />
Kelsey, G., 1430<br />
Kerckaert, J.-P., 965<br />
Kerr, L.D., 2352<br />
Kim, C.G., 928<br />
Kim, Y.-J., 2569<br />
King, D.S., 1950<br />
Kingston, J., 1986<br />
Kl/imbt, C., 1668<br />
Klar, A.J.S., 186<br />
Klement, J.F., 745<br />
Kloter, U., 1082<br />
Knowles, B., 1190<br />
Kojima, T., 50<br />
Kole, R., 631<br />
Kolter, R., 2646<br />
Kooyer, S., 2125<br />
Komberg, R.D., 296, 1305,<br />
2282<br />
Komberg, T.B., 2635<br />
Kosman, D., 1518, 1728<br />
Kouzarides, T., 1810<br />
Kozmik, Z., 1589<br />
Kfiimer, A., 631<br />
Kranz, R.G., 268<br />
Krasnow, M.A., 2177<br />
Kraus, K.W., 284<br />
Krause, H.M., 1740<br />
Kretzschmar, M., 761<br />
Krisch, H.M., 149<br />
Kristie, T.M., 2047<br />
Krug, R.M., 255<br />
Krumm, A., 2201<br />
Kfies, U., 568<br />
Kung, H.-f., 1631<br />
Kuo, A., 29, 2513<br />
Kuras, R., 1373<br />
Lachance, P., 481<br />
Lai, J.-S., 2058<br />
Laimins, L.A., 105<br />
Lambowitz, A.M., 1357<br />
Lane, M.D., 533<br />
Lane, W.S., 837<br />
Laney, J.D, 1531<br />
LaPointe, J.W., 2282<br />
Laurent, B.C., 1707<br />
Lauter, F.-R., 2373<br />
Laybourn, P.J., 2270<br />
Lazaris-Karatzas, A., 1631<br />
Leder, A., 2513<br />
Leder, P., 29, 2513<br />
Lee, B.-U., 401<br />
Lee, G., 61<br />
Lee, H.-s., 284<br />
Lee, W.M.F., 81<br />
Lee, Y., 1783<br />
Lees, E., 1874<br />
Lehmann, R., 2312<br />
Lepesant, J.-A., 1019<br />
Levine, A.J., 1143<br />
Levine, M., 1518, 1728<br />
Lew, D.J., 2021<br />
Li, G., 761<br />
Li, L., 676<br />
Li, S., 401<br />
Lieber, M.R., 1553<br />
Lieberman, P.M., 1964<br />
Lin, F.-T., 533<br />
Lin, L., 1071<br />
Lindahl, L., 2655<br />
Lindquist, S., 1402<br />
Link, A.J., 2646<br />
Lipsick, J., 2524<br />
Lis, J.T., 284, 2190<br />
Liu, Y.-1., 1631<br />
Livingston, D.M., 953<br />
Loomis, W.F., 1058<br />
Lorch, Y., 2282<br />
Loros, J.J., 2382<br />
Lowell, J.E., 2088<br />
Lfihrmann, R., 631<br />
Lund, E., 1097<br />
Lfischer, B., 71<br />
Luse, D.S., 1342<br />
Lyman, S.D., 1832<br />
Lynn, A.J., 788<br />
Maddock, I.R., 825<br />
Madore, S.J., 2077<br />
Maeda, T., 2455<br />
Mahdavi, V., 1783<br />
Maher, M., 745<br />
Malim, M.H., 2077<br />
Malone, C., 2010<br />
Malynn, B.A., 2248<br />
Mangelsdorf, D.J., 329<br />
Maniatis, T., 454, 466<br />
Manley, J.L., 304, 1654, 2569<br />
Manoukian, A.S., 1740<br />
Marini, N.J., 557<br />
Markiewicz, P., 2010<br />
Matthews, M.B., 2478<br />
Maurer-Fogy, I., 1589<br />
McCarrey, J., 705<br />
McCarty, D.R., 609<br />
McGinnis, W., 1071<br />
McGuffin, M.E., 715<br />
McKeithan, T.W., 2352<br />
McKnight, S.L., 2502<br />
Meisler, M.H., 1457<br />
Meisteremst, M., 761<br />
Mendoza, G.E., 848<br />
Merlino, G., 345<br />
Messmer, S., 1241<br />
Meulia, T., 2201<br />
Meyer, E., 211<br />
Michaud, S., 1986<br />
Michel, F., 1373<br />
Michiue, T., 50, 1005<br />
Miller, B.L., 1770<br />
Miller, K.Y., 1770<br />
Miller, S.P., 2463<br />
Milos, P.M., 991<br />
Miner, J.N., 2491<br />
Mitcham, J.L., 788<br />
Mizuuchi, K., 2221<br />
Mochizuki, N., 2455<br />
Moens, C.B., 691<br />
Montell, D.J., 2299<br />
Moore, J., 2312<br />
Morgenbesser, S.D., 1480<br />
Morimoto, R.I., 1153<br />
Morrow, M.A., 61<br />
Moss, B., 1575<br />
Muhlrad, D., 2100<br />
Mukherjee, B., 1480<br />
Mfiller, M., 1082<br />
Murphy, S.P., 1153<br />
Musti, A.M., 1621<br />
Mutasa, E.S., 568<br />
Myers, M.P., 1153<br />
Nabel, G., 2352<br />
Nadal-Ginard, B., 1783<br />
Naeger, L.K., 1107<br />
Nagatani, A., 2364<br />
Nakanishi, S., 2620<br />
Nakata, A., 2214<br />
Nasmyth, K., 1280<br />
Nawroz, M., 497<br />
Nemeroff, M.E., 255<br />
Nevins, J.R., 177<br />
Nolan, G.P., 775<br />
Norris, J.L., 1654<br />
Nurse, P., 2035<br />
Nfisslein-Volhard, C., 619<br />
Nye, J.A., 975<br />
O'Connell, M.L., 1202<br />
OH, S.-K., 1643<br />
Ohyashiki, K., 1608<br />
Oliviero, S., 1799<br />
Olson, E.N., 676<br />
Ong, E.S., 329<br />
Oro, A.E., 329<br />
Pabich, E.K., 2463<br />
Page, A.W., 2536<br />
Page, B.D., 1414<br />
Palazzolo, M., 367<br />
Pan, K.-M., 1213<br />
Panganiban, G., 2606<br />
Parada, L.F., 2235<br />
Paranjape, S.M., 2270<br />
Park, A., 1493<br />
Park, R.E., 1518, 1728<br />
Parker, R., 2100<br />
Parma, D.H., 497<br />
Paro, R., 1241<br />
Pastemak, D., 2592<br />
Patrick, R.M., 815<br />
Pearson, R.K., 1030<br />
Pedersen, R.A., 939
Pepinsky, R.B., 105<br />
P4rez-Riba, M., 2190<br />
Perichon, R., 1019<br />
Perkins, A.S., 2235<br />
Perlman, J., 2125<br />
Perrimon, N., 1503<br />
Petersen, J.M., 975<br />
Peterson, S.R., 426<br />
Pfeifle, C., 715<br />
Pick, L., 1082<br />
Pierre, D., 223<br />
Pintel, D.J., 1107<br />
Pognonec, P., 655<br />
Pomerantz, J.L., 2047<br />
Ponticelli, A.S., 296<br />
Posakony, J.W., 1752, 2592<br />
Powell, P.A., 2592<br />
Prakash, S.S., 105<br />
Prendergast, G.C., 2429<br />
Prescott, D.M., 788<br />
Prives, C., 1143, 1886<br />
Prokipcak, R.D., 642<br />
Prusiner, S.B., 1214<br />
Purton, T., 1562<br />
Piischel, A.W., 591<br />
Qin, X.-q., 953<br />
Qiu, Y., 255<br />
Radicella, J.P., 2152<br />
Raghavan, V., 367<br />
Ramer, S.W., 1305<br />
Rapp, U.R., 545<br />
Rappolee, D.A., 939<br />
Rashid, D., 667<br />
Raybum, H., 919<br />
Razin, A., 705<br />
Reddy, S., 919<br />
Reed, R., 1986<br />
Reed, S.I., 557, 1874, 2021<br />
Reeder, R.H., 1332<br />
Reichman, R.C., 1131<br />
Reik, W., 1843<br />
Resnick, J.L., 1832<br />
Reynisdottir, I., 1886<br />
Rhodes, N., 1293<br />
Richardson, D.L., 1058<br />
Richardson, H., 2021<br />
Richardson, W.V.J., 568<br />
Richter, J.D., 2580<br />
Ricupero, S.L., 1319<br />
Rio, D.C., 1386<br />
Roberts, S., 1562<br />
Robertson, E.J., 2248<br />
Robinson, G.S., 1799<br />
Rodrigues, V., 367<br />
Roeder, R.G., 655, 761<br />
Ron, D., 439<br />
Rooney, J.W., 1319<br />
Rosbash, M., 1914<br />
Rose, L.S., 1255<br />
Rosen, C.A., 655, 745, 1899<br />
Rosenberg, M.P., 1457<br />
Rosenkrans, L., 609<br />
Ross, J., 642<br />
Rossant, J., 1, 691<br />
Rossi, J.M., 1402<br />
Roth, M.B., 837<br />
Roth, S., 619<br />
Roth, S.Y., 411<br />
Rothman-Denes, L.B., 2010<br />
Rothstein, J.L., 1190<br />
Ruben, S.M., 745, 1899<br />
Rudner, D.Z., 2088<br />
Ruley, H.E., 919<br />
Ruppert, S., 1430<br />
Russo, V.E.A., 2373<br />
Rutledge, B.J., 1503<br />
Rutter, W.J., 2165<br />
RCrth, P., 2299<br />
Sachs, A.B., 2088<br />
Saga, Y., 1821<br />
Saigo, K., 50, 1005<br />
Sakakura, T., 1821<br />
Salds, F.J., 1202<br />
Samuelson, L.C., 1457<br />
Sandmeyer, S.B., 117<br />
Sandri-Goldin, R.M., 848<br />
Sarnow, P., 1643<br />
Sasai, Y., 2620<br />
Sasaki, H., 1843<br />
Sassoon, D.A., 2235<br />
Savant-Bhonsale, S., 1927<br />
Sawa, H., 244<br />
Schedl, A., 1430<br />
Scheidereit, C., 761<br />
Scheinman, R.I., 1899<br />
Schmid, E., 1430<br />
Schmitt, M.E., 1975<br />
Schoborg, R.V., 1107<br />
Schreiber, H., 1444<br />
Schultz, G.A., 939<br />
Schultz, M.C., 1332<br />
Schuster, H., 2409<br />
Schfitz, G., 1430<br />
Scott, M., 1213<br />
Scott, M.P., 1643<br />
Sebastian, B., 578<br />
Segal, D., 715<br />
S4galat, L, 1019<br />
Seiki, M., 2066<br />
Selegue, J., 2606<br />
Shapiro, L., 825, 2395<br />
Sharp, P.A., 2047<br />
Shemer, R., 705<br />
Shigemoto, R., 2620<br />
Shilo, B.-Z., 1668<br />
Shimizu, M., 411<br />
Shimkets, L.J., 401<br />
Shimura, Y., 244<br />
Shinagawa, H., 2214<br />
Shore, D., 801<br />
Shub, D.A., 1373<br />
Siebel, C.W., 1386<br />
Simon, R., 2580<br />
Simpson, R.T., 411<br />
Singh, J., 186<br />
Singson, A., 2592<br />
Skames, W.C., 903<br />
Skeath, J., 2606<br />
Skowronski, J., 1190<br />
Sloan-Brown, K., 1229<br />
Smith, G.H., 345<br />
Smith, M.R., 1631<br />
Smoot, L.B., 1783<br />
Snow, C.M., 1457<br />
Snyder, M., 497, 1414<br />
Sobolevski, S., 497<br />
Solomon, J., 1402<br />
Solomon, N., 1402<br />
Solter, D., 1190<br />
Sonenberg, N., 1631<br />
Sontheimer, E.J., 2542<br />
Spiegelman, B.M., 1799<br />
Spotts, G.D., 1229<br />
Spradling, A.C., 2443<br />
Sprague Jr., G.F., 1293<br />
Sprenger, F., 2327<br />
Springer, M.L., 1052<br />
Stahle, C., 345<br />
Stanton, B.R., 2235<br />
Steinhauer, W.R., 233<br />
Steitz, J.A., 2542<br />
Sternglanz, R., 1332<br />
Stevenson, B.J., 1293<br />
Stewart, V., 2248<br />
Stillman, D.J., 93<br />
Stockhaus, J., 2364<br />
Stolk, J.A., 837<br />
Strickland, S., 1202<br />
Strouboulis, J., 1857<br />
Struhl, K., 296, 1799<br />
Sturm, K.S., 939<br />
Stutz, F., 1914<br />
Sugimoto, K., 2021<br />
Sumimoto,.H., 655<br />
Surani, M.A., 1843<br />
Sussel, L., 801<br />
Sutherland, J.A., 1810<br />
Sutton, A., 2417<br />
Tabata, T., 2635<br />
Tagawa, Y., 2620<br />
Taira, M., 356<br />
Takahagi, M., 2214<br />
Tamai, K., 93<br />
Taphouse, C.R., 390<br />
Taraboulos, A., 1213<br />
Tassan, J.-P., 2580<br />
Teng, M., 1444<br />
Tessarollo, L., 2235<br />
Thiele, D.J., 93<br />
Thies, E., 1430<br />
Tihy, F., 1373<br />
Tiley, L.S., 2077<br />
Ting, C.-N., 1457<br />
Tjian, R., 1493, 1950<br />
Tolar, L.A., 2152<br />
Torchia, M., 1213<br />
Toyama, K., 1608<br />
Trawick, D.R., 268<br />
Trumpp, A., 14<br />
Tsai, S., 2258<br />
Tsuchihashi, Z., 511<br />
Tsuchiya, H., 2066<br />
Tullis, G.E., 1107<br />
Turcotte, B., 2001<br />
Turksen, K., 1444<br />
Tymon, A.M., 568<br />
Ulrich, E., 876<br />
Urb~inek, P., 1589<br />
Urven, L., 705<br />
Utans, U., 631<br />
Vaessin, H., 2137<br />
Van Doren, M., 2592<br />
Vasil, I.K., 609<br />
Vasil, V., 609<br />
Verma, I.M., 667, 2352<br />
yon Melchner, H., 919<br />
Walker, K., 1143<br />
Walsh, K., 815<br />
Wampler, S.L., 1542<br />
Wamsley, P., 2352<br />
Wang, C., 2312<br />
Wang, J., 2165<br />
Wang, W., 1716<br />
Wasylyk, B., 965<br />
Wasylyk, C., 965<br />
Wegner, J., 591<br />
Weintraub, H., 1466<br />
Werb, Z., 939<br />
Westerfield, M., 591<br />
Westhof, E., 1373<br />
Whittaker, L., 2524<br />
Wickens, M., 1914<br />
Wieschaus, E., 1255<br />
Wild, J., 1165<br />
Wilson, J.L., 1131<br />
Winston, F., 1319, 2288<br />
Wisdom, R., 667<br />
Wolfner, M.F., 284<br />
Wright, J.H., 197<br />
Wu, J., 1770<br />
Wyatt, J.R., 2542<br />
Xin, J.-H., 481<br />
Xu, M.-Q., 1373<br />
Yagi, T., 1821<br />
Yamamoto, K.R., 2491<br />
Yamamoto, M., 2455<br />
Yancopoulos, G.D., 61<br />
Yang, S.-L., 1213<br />
Yang, X.W., 1120<br />
Yanofsky, C., 1052, 2373<br />
Yazdanbakhsh, K., 1518<br />
Yen, J., 667<br />
Yoon, H., 2463<br />
Younger-Shepherd, S., 2137<br />
Yu, Q.-C., 1444<br />
Yu, Y.-T., 1783<br />
Yue, L., 2443<br />
Yuen, I.S., 390<br />
Yura, T., 1165<br />
Zahler, A.M., 837<br />
Zakian, V.A., 197<br />
Zambetti, G.P., 1143<br />
Zaret, K.S., 991<br />
Zeller, R., 14<br />
Zengel, J.M., 2655<br />
Zhang, K., 1503<br />
Zhang, Q., 2352<br />
Zhao, Q., 1107<br />
Zhong, T., 2417<br />
Zhou, J.Y., 329<br />
Zhou, Q., 1964<br />
Ziff, E.B., 2429<br />
Zuo, P., 2569<br />
GENES & DEVELOPMENT 2671
Subject Index, <strong>Volume</strong> 6 (<strong>1992</strong>)<br />
Abdomen formation, Drosophila, role of<br />
Pumilio and Nanos activity<br />
(Barker et al.), 2312-2326<br />
Abscisic acid (ABA), maize seed matura-<br />
tion, C1 gene activation (Hat-<br />
tori et al.), 609--618<br />
ACE2, yeast transcriptional activator<br />
(Dohrmann et al.), 93-104<br />
achaete (ac) Drosophila gene<br />
auto- and cross-regulatory activities<br />
antagonized by emc gene (Van<br />
Doren et al.), 2592-2605<br />
controlled by axis patterning genes<br />
(Skeath et al.), 2606-2619<br />
Acidic activation domain, of VP16 (Tiley<br />
et al.), 2077-2087<br />
Acidic activator, GAL4-AH (Wang et al.),<br />
1716-1727<br />
Activation domain, conserved motifs in<br />
Fos and lun (Sutherland et al.),<br />
1810-1819<br />
Activator region, cell-type-specific, of<br />
c-Jun (Baichwal et al.), 1493-<br />
1502<br />
Adducin, role in Drosophila life cycle<br />
(Yue and Spradling), 2443-2454<br />
Adenovirus E la protein, inhibition of<br />
myogenic differentiation (Braun<br />
et al.), 888-902<br />
Adh gene<br />
Drosophila and man, conserved regu-<br />
latory unit (Falb and Maniatis),<br />
454-465<br />
fat body-specific enhancers, CREB/<br />
ATF binding to (Abel et al.),<br />
466-480<br />
Adipocyte-specific genes, transcription<br />
activation by C/EBP (Lin and<br />
Lane), 533-544<br />
AEF-1, competitive binding with C/EBP<br />
(Falb and Maniatis), 454-465<br />
Albino-deletion complex, mice (Ruppert<br />
et al.), 1430-1443<br />
Albumin promoter, mouse liver tissue,<br />
transcription complexes on (Mi-<br />
los and Zaret), 991-1004<br />
alf/hsdr-I region, lethal albino mice<br />
(Ruppert et al.}, 1430-1443<br />
Allelic diversity, of maize B regulatory<br />
gene (Radicella et al.), 2152-<br />
2164<br />
oq-Antitrypsin gene, extinction of (Bulla<br />
et al.), 316-327<br />
a 2 repressor, and nucleosome position-<br />
ing (Roth et al.), 411-425<br />
Alternative pre-mRNA splicing, model<br />
for mechanism (Siebel et al.),<br />
1386-1401<br />
Alternative splicing<br />
Drosophila otu transcript (Steinhauer<br />
and Kalfayan), 233-243<br />
2672 GENES & DEVELOPMENT<br />
mediated by group I intron core<br />
(Michel et al.), 1373-1385<br />
mouse ld locus (Jackson-Grusby et al.},<br />
29-37<br />
3' splice site choice in yeast (Frank and<br />
Guthrie), 2112-2124<br />
U1 snRNP interaction with 3' splice<br />
site factor U2AF65 (Hoffman<br />
and Grabowski), 2554-2568<br />
Amino acid (methionine) deprivation,<br />
and translational control (Hann<br />
et al.), 1229-1240<br />
Ankyrin repeats, of GABPB, interaction<br />
with GABPa (Brown and Me-<br />
Knight), 2502-2512<br />
Antennapedia mRNA, Drosophila ho-<br />
meotic gene, internal ribosome<br />
binding (OH et al.I, 1643-1653<br />
Anthocyanin<br />
biosynthesis, maize seed maturation<br />
(Hattori et al.), 609--618<br />
pigmentation pathway, maize (Goff et<br />
al.), 864-875<br />
production, distinct tissue specifici-<br />
ties determined by allelic diver-<br />
sity of maize B gene (Radicella<br />
et al.), 2152-2164<br />
Antirepressor, product of ant gene in<br />
bacteriophage Pl and P7, syn-<br />
thesis repressed by c4 gene<br />
product (Biere et al.), 2409-2416<br />
Antisense inhibition, immI region of<br />
bacteriophages Pl and P7 (Biere<br />
et al.), 2409-2416<br />
AP-I<br />
binding site, of oncogene-responsive<br />
element (Bruder et al.}, 545-556<br />
family of regulatory proteins, c-Jun<br />
(Baichwal et al.), 1493-1502<br />
interaction with glucocorticoid recep-<br />
tor at composite receptor ele-<br />
ment (Miner and Yamamoto),<br />
2491-2501<br />
transcription factors, and cellular<br />
transformation (Oliviero et al.),<br />
1799-1809<br />
Aspergillus nidulans, cell pattern forma-<br />
tion and StuA gene (Miller et<br />
al.), 1770-1782<br />
Attenuation<br />
E. coli S10 operon (Zengel and Lin-<br />
dahl), 2655--2662<br />
N-myc (Morrow et al.), 61-70<br />
Attenuation/termination. See Termina-<br />
tion/attenuation.<br />
Autogenous control mechanism, E. coli<br />
r-protein L4 regulates S10 op-<br />
eron (Zengel and Lindahl),<br />
2655-2662<br />
AUUUA motifs, and mRNA instability<br />
(Savant-Bhonsale and Cleve-<br />
land), 1927-1939<br />
Avian cells, telomere binding-protein<br />
MF3 (Gualberto et al.), 815-824<br />
Axis<br />
formation, X. laevis, blastopore lip-<br />
specific gene IDirksen et al.),<br />
599--608<br />
-patterning genes, Drosophila [Skeath<br />
et al.), 2606-2619<br />
B<br />
B-cell differentiation, BSAP expression<br />
(Adams et al.I, 1589-1607<br />
b-HLH proteins, Drosophila, interaction<br />
with dl morphogen (Ip et al.),<br />
1728-1739<br />
Bacteriophage h, Rex-mediated cell<br />
death (Parma et al.}, 497-510<br />
Bacteriophage T4<br />
gene 32, RNase E's role in mRNA pro-<br />
cessing (Ehretsmann et al.),<br />
149-159<br />
sunY intron (Michel et al.), 1373-1385<br />
Bacteriophages P1 and P7, antisense in-<br />
hibition in immI region (Biere<br />
et al.), 2409-2416<br />
Bar homeo box genes, Drosophila X<br />
chromosome, BarH1 and BarH2<br />
(Higashijima et al.}, 1005--1018<br />
Bar region, Drosophila eye development,<br />
dual homeo box genes (Higashi-<br />
jima et al.), 50-60<br />
Basic helix-loop-helix proteins, Droso-<br />
phila ac and sc (Van Doren et<br />
al.), 2592-2605<br />
bcl-3 proto-oncogene, encodes IKB pro-<br />
tein (Kerr et al.), 2352-2363<br />
13-globin<br />
gene<br />
chick, role of erythroid-specific en-<br />
hancer binding factor cGATA-1<br />
{Fong et al.), 521-532<br />
human, homologous recombination<br />
into LCR (Kim et al.), 928-938<br />
locus, human, developmental regula-<br />
tion of in transgenic mice<br />
(Stouboulis et al.), 1857-1864<br />
bHLH<br />
domain, of Myf-5, target of inhibition<br />
by Ela (Braun et al.), 888-902<br />
motif, maize transcriptional activa-<br />
tors, B and R (Golf et al.), 864-<br />
875<br />
Bicoid (bcd) morphogen, and stripes in<br />
Drosophila embryo (Ip et al.),<br />
1728-1739<br />
Biogenesis, bacterial cytochrome c<br />
(Beckman et al.}, 268-283<br />
Biphasic effect, of Max on Myc cotrans-<br />
formation activity (Prendergast<br />
et al.), 2429-2439<br />
Blastopore lip, Xenopus, axis formation<br />
(Dirksen et al.), 599--608<br />
Blue light inducible gene, N. crassa, bli-7<br />
is eas gene (Lauter et al.), 2373-<br />
2381<br />
Bovine papillomavirus transgenic mice,
fibrosarcoma development {Bos-<br />
sy-Wetzel et al.), 2340-2351<br />
Branch migration, promoted by RuvA-<br />
RuvB interaction with Holliday<br />
junction (Iwasaki et al.), 2214-<br />
2220<br />
breathless (btl), Drosophila FGF receptor<br />
homolog, and cell migration<br />
(Kl~imbt et al.), 1667-1678<br />
BRF1, a TFIIB-related factor involved in<br />
RNA Pol III transcription (Col-<br />
bert and Hahn), 1940-1949<br />
BSAP, paired domain transcription fac-<br />
tor, homology between mouse<br />
and man (Adams et al.), 1589-<br />
1607<br />
Budding yeast, Saccharomyces cerevi-<br />
siae, in vivo DNA methylation<br />
by foreign methylases as probe<br />
for chromatin structure (Singh<br />
and Klar), 186-196<br />
bZIP fusion protein, Hlf, altered proper-<br />
ties in acute leukemia (Hunger<br />
et al.), 1608-1620<br />
C<br />
C signal, CsgA gene product entrains<br />
Myxococcus development (Li et<br />
al.), 401-410<br />
c-Jun, cell-type-specific activator region,<br />
two regulatory domains {Baich-<br />
wal et al.), 1493-1502<br />
c-Myb, carboxy-terminal elements of,<br />
negative regulation (Dubendorff<br />
et al.), 2524-2535<br />
c-myc<br />
modulating action, gene target of<br />
(ECA39) (Benvenisty et al.),<br />
2513--2523<br />
regulatory interaction with N-myc<br />
(Stanton et al.), 2235-2247<br />
mRNA, stability (Bernstein et al.),<br />
642-654<br />
see also myc gene.<br />
c-Myc, hetero-oligomerization to Max<br />
required for function {Kato et<br />
al.), 81-92<br />
c-rnyc (human) gene expression, block-<br />
ing of transcriptional elongation<br />
(Krumm et al.), 2201-2213<br />
c-myc 1, translational activation of<br />
(Hann et al.), 1229-1240<br />
C/EBP<br />
competitive binding with AEF-1 (Falb<br />
and Maniatis), 454--465<br />
contains HOB2 activation domain<br />
{Sutherland et al.), 1810-1819<br />
Drosophila and mammalian, func-<br />
tional and structural similarity<br />
(RCrth and Montell), 2299-2311<br />
mechanism of action (Milos and Za-<br />
ret), 991-1004<br />
role of during differentiation of 3T3-L 1<br />
preadipocytes (Lin and Lane),<br />
533-544<br />
transcription factor, CHOP inhibits<br />
function (Ron and Habener),<br />
439-453<br />
C1 complex, HSV, Oct-1 POU domain is<br />
recognized by VP16 (Pomerantz<br />
et al.), 2047-2057<br />
c4 antisense repressor, transcriptional<br />
control via translational repres-<br />
sion {Biere et al.), 2409-2416<br />
Cachexia, and TNFa expression in trans-<br />
genie mice (Cheng et al.), 1444-<br />
1456<br />
cAMP production, and S. pombe gpa2<br />
gene (Isshiki et al.), 2455-2462<br />
Carboxy-terminal domains, role in nega-<br />
tive regulation (Dubendorff et<br />
al.), 2524-2535<br />
CArG boxes, of p67 sRF binding factor, in-<br />
teraction with Taxi {Fujii et al.),<br />
2066-2076<br />
Casein kinase II (CKII), Max DNA-bind-<br />
ing activity inhibited {Berberich<br />
and Cole), 166-176<br />
Caulobacter<br />
polar localization of chemoreceptor<br />
(Alley et al.), 825-836<br />
polar morphogenesis and cell division,<br />
sigma s4 required (Brun and Sha-<br />
piro), 2395-2408<br />
cdc25 homolog, mouse, Cdc25M2 (Kak-<br />
izuka et al.), 578-590<br />
Cdc28 kinase, activation of by Clb pro-<br />
teins {cyclin-B homologs)(Rich-<br />
ardson et al.), 2021-2034<br />
cDNA libraries, preimplantation mouse<br />
development (Rothstein et al.),<br />
1190-1201<br />
Cds28 kinase, Saccharomyces cerevi-<br />
siae, transcriptional activation<br />
of Gl-specific genes (Marini and<br />
Reed), 557-567<br />
Cell cycle<br />
cyclin E/E2F association (Lees et al.),<br />
1874-1885<br />
Saccharomyces cerevisiae, cyclin-B<br />
homologs function in S phase<br />
and in G 2 (Richardson et al.],<br />
2021-2034<br />
S. pombe, checkpoint genes (Enoch et<br />
al.), 2035-2046<br />
Cell death, Rex-mediated (Parma et al.),<br />
497-510<br />
Cell fate, Drosophila<br />
eye development (Higashijima et al.),<br />
5O-60<br />
H gene controls SOP cell fate (Bang<br />
and Posakony), 1752-1769<br />
Cell growth, aberrant induction of<br />
HTLV-1 immediate early genes<br />
{Fujii et al.), 2066-2076<br />
Cell migration, Drosophila, role of FGF<br />
receptor homolog (breathless)<br />
(Klfimbt et al.), 1667-1678<br />
Cell-type-specific activator region, c-Jun,<br />
two regulatory domains (Baich-<br />
wal et al.}, 1493--1502<br />
Cellular transformation, and GCN4 and<br />
AP- 1 transcription factors {Oliv-<br />
iero et al.), 1799-1809<br />
Cellularization, Drosophila, hullo gene<br />
(Rose and Wieschaus), 1255-<br />
1268<br />
Chaperones, SecB, E. coli protein export<br />
(Wild et al.), 1165-1172<br />
Checkpoint genes, S. pombe, coupling of<br />
mitosis to completion of DNA<br />
replication (Enoch et al.), 2035-<br />
2046<br />
Chemoreceptor, bacterial, polar localiza-<br />
tion of {Alley et al.), 825-836<br />
Chicken cell lines, immortalization (Ul-<br />
rich et al.], 876-887<br />
Chicken limb deformity (ld) gene, nu-<br />
clear proteins encoded by<br />
{Trumpp et al.), 14-28<br />
CHOP, nuclear protein, dominant-nega-<br />
tive inhibitor of transcription<br />
(Ron and Habener), 439--453<br />
Chromatin<br />
binding, role of Pc chromo domain<br />
(Messmer et al.), 1241-1254<br />
protein, encoded by Drosophila ph<br />
gene (DeCamillis et al.I, 22,3-<br />
232<br />
structure<br />
budding yeast {Singh and Klar}, 186-<br />
196<br />
human ~-globin gene [Kim et al.),<br />
928-938<br />
and mRNA processing [Forrester et<br />
al.1, 1914-1926<br />
nucleosome positioning (Roth et<br />
al.), 411--425<br />
S. cerevisiae, alteration of by SNF<br />
proteins (Laurent and Carlson),<br />
1707-1715<br />
S. cerevisiae, telomeric and subtelo-<br />
meric (Wright et al.), 187-210<br />
and transcription (Hirschhom et al.),<br />
2288-2298<br />
and transcriptional activity (Croston<br />
et al.), 2270-2281<br />
templates, transcription initiation in<br />
yeast RNA polymerase tran-<br />
scription system (Lorch et al.),<br />
2282-2287<br />
of mouse Igf2 gene, and parental im-<br />
printing (Sasaki et al.), 1843-<br />
1856<br />
Chromo domain, evolutionary conserva-<br />
tion (Messmer et al.), 1241-<br />
1254<br />
Chromosomal translocations, leukomo-<br />
genesis (Hunger et al.), 1608-1-<br />
620<br />
Chromosome segregation, yeast, genes<br />
involved in (Page and Snyderl,<br />
1414-1429<br />
CIK1, yeast, SPB-associated protein<br />
{Page and Snyder), 1414-1429<br />
Circadian clock, N. crassa ccg-2 gene, in-<br />
GENES & DEVELOPMENT 2673
teracting role with light (Bell-<br />
Pedersen et al.), 2382-2394<br />
Clb proteins, cyclin-B homologs from<br />
yeast, role during mitosis (Rich-<br />
ardson et al.), 2021-2034<br />
CLB5 novel B cyclin, Saccharomyces<br />
cerevisiae, role in S phase (Ep-<br />
stein and Cross), 1695-1706<br />
CMF (conditional medium factor), Dic-<br />
tyostelium density-sensing mech-<br />
anism (Jain et al.), 390--400<br />
Cofactors, interaction with yeast HAP1<br />
DNA-binding domain (Turcotte<br />
and Guarente), 2001-2009<br />
Coliphage N4, double-stranded DNA vi-<br />
rus, early promoter activation<br />
by supercoiling and SSB (Mark-<br />
iewicz et al.), 2010-2019<br />
Composite response element, plfg, AP-1<br />
and glucocorticoid receptor in-<br />
teraction (Miner and Ya-<br />
mamoto), 2491-2501<br />
con gene expression, N. crassa sporula-<br />
tion pathway (Springer and<br />
Yanofsky), 1052-1057<br />
Cone cell formation, Drosophila, dual<br />
Bar homeo box genes (Higashi-<br />
jima et al.), 50-60<br />
Conidia, N. crassa (Lauter et al.), 2373-<br />
2381<br />
Conidiation, A. nidulans, cell pattern<br />
formation (Miller et al.), 1770-<br />
1782<br />
Conserved regulatory unit, Drosophila,<br />
Adh gene (Falb and Maniatis),<br />
454-465<br />
Coprinus cinereus, A mating-type gene<br />
complexes (Kfiues et al.), 568-<br />
577<br />
Couch potato {cpo) gene, Drosophila<br />
PNS functioning (Bellen et al.),<br />
2125-2136<br />
CREB/ATF transcriptional regulatory<br />
proteins, BBF-2 (Abel et al.),<br />
466--480<br />
CsgA gene product, Myxococcus devel-<br />
opment {Li et al.), 401-410<br />
CTS1 gene, yeast, regulation by ACE2<br />
{Dohrmann et al.), 93-104<br />
Culmination, Dictyostelium sporulation<br />
(Richarson and Loomis), 1058-<br />
1070<br />
Cyclin E, association with E2F transcrip-<br />
tion factor (Lees et al.), 1874-<br />
1885<br />
Cyclin, S. cerevisiae, role of CLB5 in S<br />
phase (Epstein and Cross),<br />
1695-1706<br />
Cyclin-B homologs (Clb proteins, Sac-<br />
charomyces cerevisiae, func-<br />
tion in S phase and in G2 (Rich-<br />
ardson et al.), 2021-2034<br />
Cyclin/kinase complexes, regulation of<br />
E2F during different phases of<br />
cell cycle (Lees et al.), 1874-<br />
1885<br />
2674 GENES & DEVELOPMENT<br />
Cytochrome c, bacterial biogenesis<br />
(Beckman et al.), 268-283<br />
Cytoplasmic<br />
bridges (ring canals), Drosophila oo-<br />
genesis (Yue and Spradling),<br />
2443--2454<br />
inhibitory protein, IKB, interaction<br />
with NLS of NF-KB {Beg et al.),<br />
1899-1913<br />
polyadenylation, regulation of murine<br />
maternal mRNAs (Sall4s et al.},<br />
1202-1212<br />
retention, mechanism of action (Beg et<br />
al.}, 1899-1913<br />
D<br />
DAI, double-stranded RNA-activated<br />
protein kinase, RNA-binding<br />
motifs in (Green and Mathews),<br />
2478-2490<br />
Deadenylation<br />
of MFA2 yeast transcript (Muhlard and<br />
Parker), 2100-2111<br />
yeast, 3'-UTR-dependent (Lowell et<br />
al.), 2088-2099<br />
Dedifferentiation of thyroid cells, v-Ras<br />
and PKC down-regulated nu-<br />
clear PKA {Gallo et al.), 1621-<br />
1630<br />
Deletional vs. inversional V(D)J recom-<br />
bination, (Gauss and Lieber),<br />
1553-1561<br />
Density-sensing mechanism, Dictyoste-<br />
lium (Jain et al.), 390--400<br />
<strong>Development</strong>al mutations, Paramecium<br />
primaurelia, microinjection of<br />
telomeric gene (Meyer), 211-<br />
222<br />
<strong>Development</strong>al systems (Holmgren and<br />
Engel), 161-165 (meeting re-<br />
view)<br />
Dfd homeotic protein, Drosophila, func-<br />
tional specificity (Lin and<br />
McGinnis), 1071-1081<br />
Dictyostelium<br />
development, density-sensing factor<br />
(Jain et al.), 390--400<br />
G~ protein function (Hadwiger and Fir-<br />
tel), 38-49<br />
sporulation, disruption of and spore<br />
instability (Richardson and<br />
Loomis}, 1058-1070<br />
Dimerization, papillomavirus E2 protein<br />
(Prakash et al.), 105-116<br />
DNA<br />
binding<br />
activity, CKII inhibits Max ho-<br />
modimers (Berberich and Cole),<br />
166-176<br />
complex, GABP (Brown and Mc-<br />
Knight), 2502-2512<br />
complex, Max:c-Myc (Kato et al.),<br />
81-92<br />
complex Myc:Max (Blackwood et<br />
al.), 71-80<br />
domain, of AP-1 (Miner and Ya-<br />
mamoto), 2491-2501<br />
element, wild-type p53-specific<br />
(Zambetti et al.), 1143-1152<br />
and ets family members (Wasylyk et<br />
al.), 965-974<br />
factor, terminator-binding factor<br />
{TBF I)(Roberts et al.), 1562-<br />
1574<br />
inhibition of wild-type p53 binding<br />
(Bargonetti et al.), 1886-1898<br />
protein, C/EBP {RCrth and Montell),<br />
2299-2311<br />
protein, Dps, regulatory and protec-<br />
tive roles in starved E. coli<br />
(Almir6n et al.), 2646-2654<br />
protein, papillomavirus E2 protein<br />
(Prakash et al.), 105-116<br />
proteins, ets gene family (Nye et al.),<br />
975-990<br />
of Rel protein {Kerr et al.), 2352-<br />
2363<br />
melting, late step in transcription ini-<br />
tiation pathway {Wang et al.),<br />
1716----1727<br />
methylation<br />
in vivo, of yeast genes by foreign me-<br />
thylases (Singh and Klar), 186-<br />
196.<br />
and parental imprinting of mouse<br />
Igf2 gene (Sasaki et al.}, 1843-<br />
1856<br />
see also methylation.<br />
methyltransferase (DNA MTase), in<br />
preimplantation mouse em-<br />
bryos (Carlson et al.), 2536-<br />
2541<br />
processing, O. nova gene scrambling<br />
(Mitcham et al.}, 788-800<br />
repair, yeast, role of SSL1 gene product<br />
{Yoon et al.), 2463-2477<br />
replication, completion of coupled to<br />
mitosis, role of fission yeast<br />
genes IEnoch et al.), 2035-2046<br />
synapsis, molecular mechanism of<br />
(Adzuma), 1679-1694<br />
transposition, phage Mu (Baker and<br />
Mizuuchi), 2221-2232<br />
virus, coliphage N4 [Markiewicz et<br />
al.), 2010-2019<br />
DnaJ heat shock protein, role in E. coli<br />
protein export (Wild et al.),<br />
1165-1172<br />
DnaX gene, E. coli, translational frame-<br />
shifting {Tsuchihashi and<br />
Brown), 511-519<br />
Dominant interference, Myc/Max onco-<br />
genie mechanisms (Mukherjee<br />
et al.), 1480-1492<br />
Dominant-negative<br />
activity, mutant RAR~ against normal<br />
RAR~ (Tsai et al.), 2258-2269<br />
inhibitor (CHOP), of transcription fac-<br />
tors of C/EBP and LAP (Ron and<br />
Hbener), 439-453
Dorsal (dl) Drosophila morphogen<br />
nuclear transport established by sig-<br />
naling pathway (Norris and<br />
Manley), 1654-1667<br />
functional domains of (Isoda et al.),<br />
619-630<br />
initiates rhomboid (rho) stripes (Ip et<br />
al.), 1728-1739<br />
dorsal-twist interaction, Drosophila<br />
mesoderm, snail gene expres-<br />
sion (Ip et al.), 1518-1530<br />
Dorsal-ventral, polarity, Drosophila em-<br />
bryo, nuclear transport of dl<br />
{Norris and Manley), 1654-1667<br />
Dorso-ventral axis formation, Droso-<br />
phila, role of spitz gene {Rut-<br />
ledge et al.), 1503-1507<br />
Double-stranded RNA<br />
-activated protein. See DAI.<br />
and activation of DAI {Green and<br />
Mathews), 2478-2490<br />
Dps DNA-binding protein, regulatory<br />
and protective roles in starved<br />
E. coli (Almir6n et al.), 2646-<br />
2654<br />
Drosophila<br />
abdomen formation, role of Pumilio<br />
and Nanos activity {Barker et<br />
al.), 2312-2326<br />
Adh gene, conserved regulatory unit<br />
within man (Falb and Maniatis),<br />
454--465<br />
C/EBP, functional and structural sim-<br />
ilarity to mammalian C/EBP<br />
(Rerth and Montell), 2299-23 11<br />
cell migration, role of breathless (btl),<br />
an FGF receptor homolog<br />
{KIambt et al.), 1667-1678<br />
cellularization, hullo gene (Rose and<br />
Wiecschaus), 1255-1268<br />
dorsal morphogen<br />
initiates rhomboid stripes {Ip et al.),<br />
1728-1739<br />
nuclear transport (Norris and Man-<br />
Icy), 1654-1667<br />
external sensory (es) organs, subtype<br />
determination (Higashijima et<br />
al.), 1005-1018<br />
eye development, prepattern in (Dick-<br />
son et al.), 2327-2339<br />
ftz homeo domain, helix-turn-helix<br />
motif (Furukubo-Tokunago et<br />
al.), 1082-1096<br />
hairy and Enhancer of split, rat HLH<br />
proteins HES-1 and HES-3 are<br />
structurally related to (Sasai et<br />
al.), 2620-2634<br />
homeo box genes, dual Bar genes (Hi-<br />
gashijima et al.), 50--60<br />
homeo domain functional specificity<br />
(Lin and McGinnis), 1071-1081<br />
hsp70 expression at normal tempera-<br />
ture {Feder et al.), 1402-1413<br />
mesoderm, doral-twist interactions,<br />
snail gene expression (Ip et al.),<br />
1518-1530<br />
nonessential zeste gene, activates Ubx<br />
promoter (Laney and Biggin),<br />
1531-1541<br />
oogenesis, hts gene encodes homolog<br />
of adducin (Yue and Spradling},<br />
2443-2454<br />
ovarian development, otu mutations<br />
(Steinhauer and Kalfayan), 233-<br />
243<br />
P-element splicing iSiebel et al.),<br />
1386-1401<br />
Pc chromo domain, functional role of<br />
(Messmer et al.), 1241-1254<br />
pair-rule gene eve protein functions<br />
as concentration-dependent mor-<br />
phogen (Manoukian and Krause),<br />
1740-1751<br />
pan-neural gene (dpn) with HLH motif<br />
(Bier et al.), 2137-2151<br />
PNS, couch potato protein, homology<br />
to RNA-binding proteins {Bel-<br />
len et al.), 2125-2136<br />
polyhomeotic gene (ph), encodes chro-<br />
matin protein (DeCamillis et<br />
al.), 223-232<br />
position-specific transcriptional re-<br />
pression (Geyer and Corces),<br />
1865-1873<br />
pqp gene is wings down {WDN) gene<br />
(S4galat et al.), 1019-1029<br />
preIC assembly, differential regulation<br />
of by UBX and EVE (Johnson<br />
and Krasnow), 2177-2189<br />
promoter-paused RNA pol II (Giardina<br />
et al.), 2190-2200<br />
proneural gene expression (Skeath et<br />
al.), 2606-2619<br />
relationship between engrailed (en)<br />
and hedgehog (hh) (Tabata et<br />
al.), 2635-2645<br />
RNA polymerase pausing on hsp70<br />
(Lee et al.), 284-295<br />
RNA-binding protein RBP1, func-<br />
tional similarity to human<br />
splicing factor ASf/SF2 (Kim et<br />
al.), 2569-2578<br />
scalloped (SD) gene encodes evolu-<br />
tionarily conserved transcrip-<br />
tion factor {Campbell et al.),<br />
367-379<br />
sensory organ development, Hairless<br />
gene (H), protein controls alter-<br />
native cell fate (Bang and Posa-<br />
kony), 1752-1769<br />
sloppy paired locus, segmentation<br />
(Grossniklaus et al.), 1030-1051<br />
spitz gene, encodes putative EGF-like<br />
growth factor {Rutledge et al.),<br />
1503-1507<br />
TFIID-promoter interactions {Colgan<br />
and Manley), 304-315<br />
transcription factor IIB {dTFIIB) (Warn-<br />
pier and Kadonaga), 1542-1552<br />
transcriptional activator, CREB/ATF<br />
family (Abel et al.), 466-480<br />
wing imaginal disc, spatial patterning<br />
of proneural clusters (Van<br />
Doren et al.), 2592-2605<br />
Dynamin, GTP-binding domain {Jones<br />
and Fangman}, 380-389<br />
E proteins, association with Id, inhibi-<br />
tion of muscle differentiation<br />
(Jen et al.), 1466-1479<br />
E2a gene, chromosomal translocations<br />
in acute leukemias {Hunger et<br />
al.), 1608-1620<br />
E2F transcription factor<br />
and RB {Qin et al.), 953-964<br />
association with cyclin E [Lees et al.I,<br />
1874-1885<br />
interaction with pRB {Hiebert et al.),<br />
177-185<br />
eas N. crassa gene<br />
allelism with ccg-2 (Bell-Pedersen et<br />
al.), 2382-2394<br />
structural gene for the rodlet protein<br />
(Lauter et al.), 2373-2381<br />
ECA39 gene, target gene of c-Myc regu-<br />
lation (Benvenisty et al.), 2513-<br />
2523<br />
eIF-4E-induced transformation, medi-<br />
ated by Ras signaling pathway<br />
{Lazaris-Karatzas et al.), 1631-<br />
1642<br />
Elongation factor<br />
SII, facilitates transcript cleavage<br />
{Izban and Luse), 1342-1356<br />
TFIIF, interaction with Tat {Kato et<br />
al.), 655-666<br />
Embryogenesis<br />
Drosophila, C/EBP required for devel-<br />
opment (Rerth and Montell),<br />
2299-23 11<br />
(Holmgren and Engel), 161-165 {meet-<br />
ing review)<br />
mouse, DNA methylation {Kafri et<br />
al.), 705-714<br />
TN-deficient mice develop normally<br />
(Saga et al.), 1821-1831<br />
Embryonal stem cells, gene disruption<br />
by promoter trap vectors (yon<br />
Melchner et al.), 919-927<br />
Embryonic<br />
development, vertebrate, mutational<br />
analysis of (Rossant and Hop-<br />
kins), 1-13 {Review)<br />
lethality, loss of N-myc function<br />
(Charron et al.), 2248-2257,<br />
(Stanton et al.], 2235-2247<br />
stem (ES) cells, gene trap approach in<br />
{Skames et al.}, 903-918<br />
Endoribonuclease<br />
RNase E, E. coli, specificity of (Ehrets-<br />
mann et al.), 149-159<br />
RNase MRP, nuclear role of (Schmitt<br />
and Clayton), 1975-1985<br />
engrailed {en) Drosophila gene, regulates<br />
expression of hh {Tabata et al.),<br />
2635-2645<br />
GENES & DEVELOPMENT 2675
Enhancer of split [E(spl)], Drosophila, rat<br />
HLH proteins HES-1 and HES-3<br />
are structurally related to (Sasai<br />
et al.}, 2620-2634<br />
Enhancer-binding factors, counteract<br />
chromatin-mediated repression<br />
(Croston et al.}, 2270-2281<br />
Enhancers. See also Promoter-enhancer<br />
interaction.<br />
Epidermal growth factor [EGF), Droso-<br />
phila spitz gene encodes puta-<br />
tive homologous protein (Rut-<br />
ledge et al.), 1503-1507<br />
Escherichia coli<br />
branch migration, promoted by RuvA<br />
and RuvB proteins (Iwasaki et<br />
al.), 221 4-2220<br />
endoribonuclease RNase E, specificity<br />
of (Ehretsmann et al.}, 149-159<br />
mRNA stabilization by 5'-stem-loop<br />
structure (Emory et al.),<br />
135-148<br />
N4 early transcription, single-stranded<br />
DNA-binding protein (SSB) re-<br />
quired for (Markiewicz et al.),<br />
2010-2019<br />
protein export, role of heat shock pro-<br />
teins DnaK and DnaJ {Wild et<br />
al.), 1165-1172<br />
RecA protein, mediates stable DNA<br />
synapsis (Adzuma), 1679-1694<br />
S10 operon, regulation by ribosomal<br />
protein L4 {Zengel and Lindahl),<br />
2655-2662<br />
translational frameshifting, dnaX gene<br />
(Tsuchihashi and Brown), 511-<br />
519<br />
ets<br />
family members, different trans-acting<br />
properties of {Wasylyk et al.),<br />
965-974<br />
oncogene family, new member PEA3<br />
(Xin et al.), 481-496<br />
-related proteins, two newly defined<br />
proteins (ER81 and ER71)<br />
(Brown and McKnight), 2502-<br />
2512<br />
ets-1 proto-oncogene, eukaryotic tran-<br />
scriptional regulator (Nye et<br />
al.}, 975-990<br />
Ets<br />
-binding site, of oncogene-responsive<br />
element (Bruder et al.), 545-556<br />
transcription activation by (Wasylyk<br />
et al.), 965-974<br />
ETS<br />
domain, specificity of DNA binding<br />
(Nye et al.), 975-990<br />
family, DNA-binding and protein-pro-<br />
tein interaction specificity<br />
(Brown and McKnight), 2502-<br />
2512<br />
even-skipped (eve}<br />
pair-rule gene, Drosophila, Eve func-<br />
tions as concentration depen-<br />
2676 GENES & DEVELOPMENT<br />
dent morphogen (Manoukian<br />
and Krause), 1740-1751<br />
Drosophila, homeo domain protein<br />
EVE (Johnson and Krasnow),<br />
2177-2189<br />
Evolution of gene regulation, role for ret-<br />
rotransposition (Ting et al.),<br />
1457-1465<br />
Evolutionary conservation<br />
transcription factors (Campbell et al.),<br />
367-379<br />
vertebrate limb pattern formation<br />
{Trumpp et al.), 14-28<br />
Exon<br />
definition, effect of nonsense muta-<br />
tions on (Naeger et al.), 1107-<br />
1119<br />
selection, positive regulation by U1<br />
snRNP/U2AF65 communica-<br />
tion {Hoffman and Grabowski),<br />
2554-2568<br />
Exonucleases, 5'-3' and 3'-5' (Ctyman<br />
and Belfort), 1269-1279<br />
External sensory (es) organs, Drosophila,<br />
subtype determination (Higash-<br />
ijima et al.), 1005-1018<br />
Extinction, of a~-antitrypsin gene ex-<br />
pression (Bulla et al.), 316-327<br />
Extracellular matrix protein, normal de-<br />
velopment of TN-deficient<br />
mice (Saga et al.), 1821-1831<br />
extramacrochaetae (emc) Drosophila<br />
gene, role in controlling spatial<br />
pattern of ac and sc transcrip-<br />
tion (Van Doren et al.), 2592-<br />
2605<br />
Eye development, Drosophila, dual Bar<br />
homeo box genes (Higashijima<br />
et al.), 50-60<br />
F<br />
Fibroblast growth factor (FGF) receptor,<br />
Drosophila, analysis of ho-<br />
molog (breathless)(Kl~imbt et<br />
al.), 1667-1678<br />
Fibrosarcoma development, functional<br />
role of transcription factors<br />
JunB and c-Jun (Bossy-Wetzel et<br />
al./, 2340-2351<br />
Fission yeast checkpoint genes, coupling<br />
of mitosis to completion of<br />
DNA replication (Enoch et al.),<br />
2035--2046<br />
5' splice site, site-specific cross-linking<br />
of mammalian U5 snRNP to<br />
(Wyatt et al.), 2542-2553<br />
Flagelllum biosynthesis, Caulobacter,<br />
role of r factor (Brun and Sha-<br />
piro), 2395-2408<br />
fork head domain<br />
Drosophila, novel putative DNA-bind-<br />
ing domain (Grossniklaus et<br />
al.), 1030-1051<br />
Xenopus, blastopore lip-specific gene<br />
(Dirksen et al.), 599-608<br />
Formins, ld alternatively spliced tran-<br />
script protein products (Jack-<br />
son-Grusby et al.), 29-37<br />
Fos<br />
and muscle transcription, repression<br />
of (Li et al.), 676-689<br />
oncoprotein, HOB motifs of (Suther-<br />
land et al.), 1810-1819<br />
see also oncoproteins<br />
FosB protein, transactivation domain<br />
missing in FosB2 (Wisdom et<br />
al.), 667--675<br />
FosB2 protein, lacks transactivation do-<br />
main present in FosB (Wisdom<br />
et al.), 667--675<br />
Fumaryl acetoacetate hydrolase, gene for<br />
within al[/hsdr-1 region, lethal<br />
albino mice (Ruppert et al.),<br />
1430--1443<br />
Fungal spore development, interacting<br />
role of light and circadian clock<br />
(Betl-Pedersen et al.), 2382-2394<br />
FUS3 kinase, phosphorylation of, S. cere-<br />
visiae (Gartner et al.}, 1280-<br />
1292<br />
fushi tarazu (ftz) homeo domain, Droso-<br />
phila, helix-turn-helix motif<br />
{Furukubo-Tokunago et al.),<br />
1082-1096<br />
G<br />
G protein<br />
Dictyostelium, Ga4 subunit analysis of<br />
(Hadwiger and Firtel), 38--49<br />
S. pombe, gpa2 gene encodes Ga sub-<br />
unit involved in nutrional mon-<br />
itoring (Isshiki et al.), 2455-<br />
2462<br />
G-G base pair recognition, avian telom-<br />
eres {Gualberto et al.), 815-824<br />
GABa, target site selection by (Brown<br />
and McKnight}, 2502-2512<br />
GAGA factor, role in RNA polymerase<br />
pausing in heat shock gene (Lee<br />
et al.), 284-295<br />
GAL4-VP16 mediated antirepression, of<br />
histone HI-mediated repression<br />
(Croston et al.), 2270-2281<br />
GALII, as possible HAP1 cofactor {Tur-<br />
cotte and Guarente), 2001-2009<br />
GATA-1, promoter-enhancer interac-<br />
tions regulated by (Fong et al.),<br />
521-532<br />
Gene<br />
scrambling, O. nova (Mitcham et al.),<br />
788-800<br />
targeting, partial loss-of-function mu-<br />
tations (Moens et al.), 691-704<br />
trap vector, mouse embryonic stem<br />
cells (Skarnes et al.), 903-918<br />
Genome reorganization, Paramecium,<br />
polyploid macronucleus from<br />
diploid nucleus (Meyerl,<br />
211-222
Genomic imprinting<br />
embryonic development {Rappolee et<br />
al.), 939-952<br />
preimpantation mouse embryos (Carl-<br />
son et al.), 2536-2541<br />
Germ cell development, role of SLF<br />
(Brannan et al.), 1832-1842<br />
Globin gene switching, promoter compe-<br />
tition (Foley and Engel},<br />
730-744<br />
Glucocorticoid response element, inter-<br />
action with AP-1 (Miner and<br />
Yamamoto), 2491-2501<br />
Granulocyte monocyte colony stimulat-<br />
ing factor (GM-CSF) AU com-<br />
plex, and mRNA instability (Sa-<br />
vant-Bhonsale and Cleveland),<br />
1927-1939<br />
Group I intron, activation of catalytic<br />
core (Michel et al.), 1373-1385<br />
Group I introns, splicing of and similar-<br />
ity to tRNAs (Guo and Lam-<br />
bowitz), 1357-1372<br />
Growth suppression domain, within RB<br />
gene product (Qin et al.), 953-<br />
964<br />
Gl-specific genes, dependency on Cdc28<br />
kinase activation {Marini and<br />
Reed), 557-567<br />
GTP-binding domain, dynamin D100<br />
(Jones and Fangman), 380-389<br />
G 1 regulation, of S. cerevisiae, role of<br />
SIT4 gene (Femandez-Sarabia et<br />
al.), 2417-2428<br />
H<br />
hairless {H) Drosophila gene, protein<br />
controls SOP cell fate (Bang and<br />
Posakony), 1752-1769<br />
Hairy (h)<br />
Drosophila, rat HLH proteins HES-1<br />
and HES-3 are structurally re-<br />
lated to {Sasai et al.), 2620-2634<br />
gene product, Drosophila, pan-neural<br />
gene {dpn) closely related to<br />
(Bier et al.), 2137-2151<br />
Half-life, of c-myc mRNA {Bemstein et<br />
al.), 642-654<br />
HAP1 activator, yeast, cofactor interac-<br />
tion (Turcotte and Guarente),<br />
2001-2009<br />
Heat shock<br />
genes<br />
Drosophila, DNA melting of (Giar-<br />
dina et a1.),2190-2200<br />
RNA polymerase pausing on hsp70<br />
(Lee et al.), 284-295<br />
proteins, DnaK and DnaJ, role in E.<br />
coli protein export (Wild et al.),<br />
1165-1172<br />
response, and splicing pathway (Utans<br />
et al.), 631-641<br />
hsp70/HSF interaction (Abravaya et<br />
al.), 1153-1164<br />
hedgehog Drosophila gene, target of en<br />
regulation {Tabata et al.), 2635-<br />
2645<br />
Helix-loop-helix (HLH)<br />
-bZIP, chimeric transcription factor<br />
(Hunger et al.}, 1608-1620<br />
-ZIP domain, Max:c-Myc heteromeric<br />
complex (Kato et al.), 81-92<br />
motif, Drosophila ftz homeo domain<br />
(Furukubo-Tokunago et al.),<br />
1082-1096<br />
protein<br />
Drosophila emc {Van Doren et al.),<br />
2592-2605<br />
encoded by Drosophila dpn gene<br />
(Bier et al.), 2137-2151<br />
Id associates with E2A proteins (Jen<br />
et al.), 1466--1479<br />
and insulin (German et al.}, 2165-<br />
2176<br />
muscle-specific, myogenin and<br />
MyoD {Li et al.), 676-689<br />
rat HEAS-1 and HES-3, structural<br />
homology to Drosophila hairy<br />
and Enhancer of split (Sasai et<br />
al.), 2620-2634<br />
regulatory gene, maize B gene {Radi-<br />
celia et al.), 2152-2164<br />
zipper protein, Max, association with<br />
Myc family proteins (Black-<br />
wood et al.), 71-80<br />
Hematopoiesis {Holmgren and Engel),<br />
161-165 (meeting review)<br />
Heme transport, and bacterial cy-<br />
tochrome c biogenesis (Beck-<br />
man et al.), 268-283<br />
Hemopoietic differentiation, role of<br />
RARa transcription factor (Tsai<br />
et al.), 2258-2269<br />
Hepatic development, albumin gene ac-<br />
tivators {Milos and Zaret), 991-<br />
1004<br />
Heptapeptide repeats, of RNAP II CTD,<br />
phosphorylation of (Peterson et<br />
al.}, 426-438<br />
Herpes simplex virus<br />
Oct-1 multiprotein complex {C1) (Po-<br />
merantz et al.), 2047-2057<br />
trans-activator VP16, association with<br />
POU protein Oct-1 and Oct-2<br />
(Lai et al.), 2058-2065<br />
HES family, HLH factors, structurally re-<br />
lated to Drosophila h and E(spl)<br />
(Sasai et al.), 2620-2634<br />
Heteromeric complex, Max:c-Myc (Kato<br />
et al.), 81-92<br />
Hexagonal actin-myosin network, Dro-<br />
sophila hullo gene stabilizes<br />
(Rose and Wiecschaus), 1255-<br />
1268<br />
Histone<br />
Hi-mediated repression, counteracted<br />
by GAL4--VP 16 hybrid activator<br />
(Croston et al.), 2270-2281<br />
H4, and nucleosome positioning (Roth<br />
et al.), 411--425<br />
HIV- 1<br />
promoter, transcription regulation by<br />
NF-KB {Kretzschmar et al.),<br />
761-774<br />
VP 16 and Tat have functionally inter-<br />
changeable activation domains<br />
(Tiley et al.), 2077-2087<br />
HMG box protein, hUBF (Jantzen et al.),<br />
1950-1963<br />
HO endonuclease gene, yeast, regulated<br />
by SW15 (Dohrmann et al.), 93-<br />
104<br />
Holliday junction, E. coli protein com-<br />
plex RuvA-RuvB interaction,<br />
promotes branch migration<br />
{Iwasaki et al.), 2214-2220<br />
Homeo box<br />
-containing genes {HOX), promoter ac-<br />
tivation in transgenic zebrafish<br />
{Westerfield et al.), 591-590<br />
gene, Xlim-1 in X. laevis LIM domain<br />
{Taira et al.}, 356-366<br />
genes, Drosophila Bar region and eye<br />
development (Higashijima et<br />
al.}, 50-60<br />
Homeo domain<br />
ftz Drosophila, helix-turn-helix motif<br />
(Furukubo-Tokunago et al.),<br />
1082-1096<br />
motifs, Coprinus, A mating type gene<br />
complexes (Kiies et al.),<br />
568-577<br />
proteins<br />
Drosophila activator UBX and re-<br />
pressor EVE {Johnson and Kras-<br />
now), 2177-2189<br />
Oct-1 POU, recognition of surface<br />
{Pomerantz et al.), 2047-2057<br />
Homeo domains, Dfd and Ubx, mapping<br />
functional specificity {Lin and<br />
McGinnis), 1071-1081<br />
Homeobox genes, redundant, Drosophila<br />
BarH1 and BatH2 (Higashijima<br />
et al.), 1005-1018<br />
Homeotic<br />
complex HOM-C, Drosophila, map-<br />
ping functional specifity in Dfd<br />
and Ubx (Lin and McGinnis),<br />
1071-1081<br />
Drosophila gene, Antp, intemal ribo-<br />
some binding of mRNA (OH et<br />
al.), 1643-1653<br />
genes<br />
Drosophila repression by Polycomb<br />
group {PcG) (DeCamillis et al.),<br />
223-232<br />
Drosophila Ubx promoter activation<br />
{Laney and Biggin), 1531-1541<br />
Homologous recombination<br />
branch migration in (Iwasaki et al.),<br />
2214-2220<br />
mto human 13-globin LCR (Kim et al.),<br />
919-927<br />
role of recA protein during DNA syn-<br />
apsis {Adzuma}, 1679-1694<br />
GENES & DEVELOPMENT 2677
HPV production, in epithelial raft cul-<br />
tures (Dollard et al.), 1131-1142<br />
HSF, interaction with hsp70 (Abravaya<br />
et al.), 1153-1164<br />
hSL1, TBP-TAF complex, interaction<br />
with hUBF activation domain<br />
(Jantzen et al.), 1950-1963<br />
Hsp70, Drosophila, consequences of ex-<br />
pression at normal temperature<br />
(Feder et al.), 1402-1413<br />
HSV- 1 regulatory protein, ICP27, affects<br />
mRNA processing (Sandri-Gol-<br />
din and Mendoza), 848-863<br />
HTLV-1, Tax1 transcriptional activator<br />
and transforming protein (Fujii<br />
et al.), 2066-2076<br />
hu-li-tai shao (hts), Drosophila gene, en-<br />
codes adducin homolog {Yue<br />
and Spradling), 2443-2454<br />
hUBF activation domains, cooperative<br />
interactions with TBF-TAF<br />
complex hSL1 (Jantzen et al.),<br />
1950-1963<br />
Human<br />
hsp70 protein, interaction with HSF<br />
{Abravaya et al.), 1153-1164<br />
papillomavirus. See HPV.<br />
salivary amylase gene (AMY1C}, tis-<br />
sue-specific expression, retrovi-<br />
ral sequences required for (Ting<br />
et al.I, 1457-1465<br />
splicing factor ASF/SF2, Drosophila<br />
RNA binding protein RBP1<br />
shows functional similarity to<br />
(Kim et al.), 2569-2578<br />
Human/Mel hybrid, human B-globin<br />
LCR (Kim et al.), 928-938<br />
Hybrid cells (hepatoma/fibroblast), ex-<br />
tinction of liver specific oq-AT<br />
gene (Bulla et al.), 316-327<br />
Hydrophobin<br />
encoded by N. crassa ccg-2 gene (Bell-<br />
Pedersen et al.), 2382-2394<br />
gene family, N. crassa eas gene is<br />
member of (Lauter et al.), 2373-<br />
2381<br />
I<br />
ICP27, HSV-1 regulatory protein, post-<br />
transcriptional effect on mRNA<br />
processing (Sandri-Goldin and<br />
Mendoza), 848-863<br />
Id HLH protein, associates with E2A pro-<br />
tein, inhibition of muscle differ-<br />
entiation (Jen et al.), 1466-1479<br />
IKB protein family, bcl-3 and IKB~ are<br />
members of (Kerr et al.), 2352-<br />
2363<br />
Imaginal disc development, Drosophila,<br />
apterous (ap) gene (Cohen et<br />
al.), 715-729<br />
Immediate early genes, HTLV-1, aber-<br />
rant induction of (Fujii et al.},<br />
2066--2076<br />
immI region of bacteriophages P1 and<br />
2678 GENES & DEVELOPMENT<br />
P7, novel antisense system<br />
(Biere et al.), 2409-2416<br />
Immortalization, of chicken cells, as dis-<br />
tinct from cell transformation<br />
(Ulrich et al.), 876-887<br />
In vitro selection, of hairpin ribozymes<br />
(Berzal-Herranz et al.l, 129-134<br />
Influenza virus, nucleocytoplasmic<br />
transport of mRNA (Alonso-Ca-<br />
plen et al.), 255-267<br />
Insulin I rat gene, minienhancer com-<br />
plex (German et al.), 2165-2176<br />
Insulin receptors, preimplantation<br />
mouse embryos (Rappolee et<br />
al.), 939-952<br />
Insulin-like growth factor<br />
IGF-II/IGF-I receptor pathway in<br />
mouse embryos {Rappolee et<br />
al.), 939-952<br />
II (Igf2), mouse, parental imprinting<br />
(Sasaki et al.), 1843-1856<br />
Integration sites, of Ty3 retrovirus-like<br />
element (Chalker and Sandm-<br />
eyer), 117-128<br />
Interleukin-7 (IL-7), N-rnyc and C-myc<br />
regulation in pre-B lymphocytes<br />
(Morrow et al.), 61-70<br />
Internal eliminated sequences, O. nova,<br />
removal of (Mitcham et al.),<br />
788-800<br />
Intron<br />
core, binding by tyrosyl-tRNA synthe-<br />
tase (Guo and Lambowitz),<br />
1357-1372<br />
mobility, trans and cis requirements<br />
(Clyman and Belfort), 1269-<br />
1279<br />
Jun<br />
family of oncogenes, fibrosarcoma de-<br />
velopment (Bossy-Wetzel et al.),<br />
2340-2351<br />
and muscle transcription, repression<br />
of (Li et al.), 676-689<br />
oncoprotein, HOB motifs of (Suther-<br />
land et al.), 1810-1819<br />
see also oncoproteins<br />
K<br />
Karyogamy, yeast, genes involved in<br />
(Page and Snyder), 1414--1429<br />
Keratinocyte, differentiation {Dollard et<br />
al.), 1131-1142<br />
Keratinocytes, TNF~ production (Cheng<br />
et al.), 1444-1456<br />
Kidney development, chicken ld gene<br />
(Trumpp et al.}, 14-28<br />
Kinase<br />
cascade, role in pheromone response<br />
pathway (Stevenson et al.),<br />
1293-1304<br />
double-stranded RNA-activated pro-<br />
tein kinase (DAI), RNA-binding<br />
motifs in (Green and Mathews),<br />
2478-2490<br />
Kinases, S. cerevisiae<br />
FUS3, STEll, and STE7 (Gartner et<br />
al.), 1280-1292<br />
STE7 and STE11 (Cairns et al.), 1305-<br />
1318<br />
KMnO4, as probe for single-stranded<br />
DNA (Giardina et al.), 2190--<br />
2200, {Krumm et al.), 2201-<br />
2213<br />
L<br />
LacZ<br />
gene expression, TN-deficient mice,<br />
lacZ replaces TN (Saga et al.),<br />
1821-1831<br />
reporter, mouse ES cells, and gene trap<br />
vector (Skames et al.), 903-918<br />
LAP, transcription factor, CHOP inhib-<br />
its function (Ron and Habener),<br />
439-453<br />
Leukemogenesis, chromosomal translo-<br />
cations, oncogenic conversion<br />
by transcription factors (Hunger<br />
et al.), 1608-1620<br />
LIM<br />
domain, Xenopus laevis homeo box<br />
gene Xlim-1 (Taira et al.), 356-<br />
366<br />
gene family, Drosophila, ap gene (Co-<br />
hen et al.}, 715--729<br />
-homeo domain protein, and insulin<br />
minienhancer complex (Ger-<br />
man et al.I, 2165-2176<br />
Limb development, chicken ld gene<br />
(Trumpp et al.), 14-28<br />
Locus control region (LCR), human<br />
f~-globin gene, homologous re-<br />
combination into (Kim et al.),<br />
919-927<br />
Lung branching morphogenesis, mouse,<br />
role for N-myc {Moens et al.),<br />
691-704<br />
M<br />
Macronuclear<br />
destined sequences (MDS), O. nova,<br />
reordering and splicing<br />
(Mitcham et al.), 788-800<br />
development, Paramecium primaure-<br />
lia, telomere addition sites<br />
(Meyer), 211-222<br />
MADS gene family, MEF2 factors are<br />
members of (Yu et al.), 1783-<br />
1798<br />
Maize<br />
anthocyanin pigmentation pathway<br />
(Goff et al.), 864-875<br />
B regulatory gene, allelic diversity of<br />
(Radicella et al.}, 2152-2164<br />
seed maturation, VP 1 activation of the<br />
C1 gene (Hattori et al.), 609-618
Male sterility, resulting from activated<br />
int-3 transgenic mice (Jhappen<br />
et al.), 345-355<br />
Mammary glands, lactation deficiency,<br />
resulting from activated int-3<br />
locus (Jhappen et al.), 345-355<br />
Masked mRNA, X. laevis, activation of<br />
by cytoplasmic poly(A) elonga-<br />
tion (Simon et al.), 2580-2591<br />
Maternal<br />
effect genes, Drosophila pumilio and<br />
nanos (Barker et al.), 2312-2326<br />
morphogen, Drosophila dorsal (dl) (Ip<br />
et al.), 1728-1739<br />
mRNAs, murine, regulated by cyto-<br />
plasmic polyadenylation {Sall6s<br />
et al.), 1202-1212<br />
Mating type, Coprinus A gene com-<br />
plexes (Ktiues et al.), 568-577<br />
Max<br />
homodimer, DNA-binding activity in-<br />
hibited by CKII (Berberich and<br />
Cole), 166-176<br />
protein<br />
biphasic effect of on Myc cotransfor-<br />
mation activity (Prendergast et<br />
al.), 2429-2439<br />
functional domains of and interac-<br />
tion with c-Myc (Kato et al.),<br />
81-92<br />
helix-loop--helix zipper protein, asso-<br />
ciation with Myc family pro-<br />
teins (Blackwood et al.), 71-80<br />
interaction with Myc proteins<br />
(Mukherjee et al.), 1480-1492<br />
MCK (muscle creatine kinase)gene,<br />
identification of wild-type p53<br />
responsive element {Zambetti<br />
et al.), 1143-1152<br />
McpA chemoreceptor, C. crescentus, po-<br />
lar localization of (Alley et al.},<br />
825-836<br />
Methylation<br />
gene-specific, mouse development<br />
(Kafri et al.), 705-714<br />
patterns, preimplantation mouse em-<br />
bryos (Carlson et al.), 2536-<br />
2541<br />
MF3 protein, specificity for single<br />
stranded telomere probes (Gual-<br />
berto et al.), 815-824<br />
MFA2 yeast gene<br />
decay and deadenylation of mRNA<br />
(Muhlard and Parker), 2100-<br />
2111<br />
3'-UTR-dependent deadenylation of<br />
RNA (Lowell et al.), 2088-2099<br />
MGM1, S. cerevisiae, mitochondrial ge-<br />
nome maintenance gene (Jones<br />
and Fangman), 380-389<br />
Mice<br />
normal development of TN-deficient<br />
mice (Saga et al.), 1821-1831<br />
splicing defect in Steel ~ zH {Brannan et<br />
al.), 1832-1842<br />
Microtubule<br />
-binding protein, dynamin D100 (Jones<br />
and Fangman), 380--389<br />
function, S. cerevisiae gene involved<br />
in (Page and Snyder), 1414-1429<br />
Midblastula transition, X. laevis, tran-<br />
scription activation (Lund and<br />
Dahlberg), 1097-1106<br />
Minienhancer complex, components of<br />
(German et al.), 2165-2176<br />
Mitochondrial<br />
DNA (mtDNA), nuclear genes re-<br />
quired for maintenance (Jones<br />
and Fangman), 380-389<br />
RNA processing, tyrosyl-tRNA syn-<br />
thetase (Guo and Lambowitz},<br />
1357-1372<br />
RNA, RNase MRP (Schmitt and Clay-<br />
ton), 1975-1985<br />
Mitosis<br />
coupled to completion of DNA repli-<br />
cation, role of fission yeast<br />
genes (Enoch et al.), 2035-2046<br />
yeast, role of cyclin-B homologs {Clb<br />
proteins) (Richardson et al.),<br />
2021-2034<br />
Mitotic control, mammalian cells,<br />
mouse cdc25 homolog (Kaki-<br />
zuka et al.), 578-590<br />
MMTV, integration into int-3 locus acti-<br />
vated Notch-related flanking se-<br />
quences {Jhappen et al.),<br />
345-355<br />
Mouse<br />
cdc25 homolog, developmental ex-<br />
pression (Kakizuka et al.), 578-<br />
590<br />
embryogenesis<br />
function of N-myc during (Stanton<br />
et al.), 2235-2247, (Charron et<br />
al.), 2248-2257<br />
regulatory role of PEA3 (Xin et al.],<br />
481--496<br />
embryos, endogenous growth pathway<br />
(Rappolee et al.), 939-952<br />
limb deformity {ld) locus, alternatively<br />
spliced transcripts of (Jackson-<br />
Grusby et al.), 29-37<br />
insulin-like growth factor (Igf2) gene,<br />
parental imprinting (Sasaki et<br />
al.), 1843-1856<br />
mRNA<br />
degradation<br />
specificity of RNase E (Ehretsmann<br />
et al.), 149-159<br />
yeast, deadenylation of MFA2 tran-<br />
script (Muhlard and Parker),<br />
2100-2111<br />
export, Saccharomyces cerevisiae,<br />
RAT1 gene (Amberg et al.),<br />
1173-1189<br />
instability, and GM-CSF AU complex<br />
(Savant-Bhonsale and Cleve-<br />
land), 1927-1939<br />
processing<br />
affected by HSV-1 regulator (San&i-<br />
Goldin and Mendoza), 848-863<br />
defects of in prp20 yeast mutation<br />
{Forrester et al.), 1914-1926<br />
stability<br />
c-myc [Bemstein et al.), 642-654<br />
E. coli, 5'-stem-loop structure (Em-<br />
ory et al.I, 135-148<br />
nucleocytoplasmic transport, influ-<br />
enza virus (Alonso-Caplen et<br />
al.), 255-267<br />
MuA tetramer, DNA promoted assem-<br />
bly of (Baker and Mizuuchi},<br />
2221-2232<br />
Murine mammary tumor virus. See<br />
MMTV<br />
Muscle differentiation, inhibition of, Id<br />
association with E proteins<br />
(E2A) (Jen et al.), 1466--1479<br />
Muscle transcription, repression of by<br />
Fos and Jun (Li et al.), 676-689<br />
Muscle-specific gene regulation, MEF2<br />
factors are members of MADS<br />
family (Yu et al.), 1783-1798<br />
Mutagenic strategies, vertebrate {Ros-<br />
sant and Hopkins), 1-13 (Re-<br />
view)<br />
Mutant p53 protein, inhibits wild-type<br />
p53 binding {Bargonetti et al.),<br />
1886-1898<br />
myc gene<br />
expression, IL-7 regulated {Morrow et<br />
al. ), 61-70<br />
family, regulatory interaction between<br />
c-myc and N-myc {Stanton et<br />
al.l, 2235-2247<br />
Myc<br />
cotransformation, biphasic effect of<br />
Max on (Prendergast et al.I,<br />
2429-2439<br />
family proteins, common transforma-<br />
tion pathways including Max<br />
interaction (Mukherjee et al.),<br />
1480-1492<br />
Myc:Max, sequence-specific DNA-bind-<br />
ing complex (Blackwood et al.),<br />
71-80<br />
Myc/Max heterodimers, DNA-binding<br />
activity, unaffected by CKII<br />
{Berberich and Cole), 166-176<br />
Myocyte-specific enhancer factors 2<br />
(MEF2), members of MADS box<br />
family (Yu et al.), 1783--1798<br />
MyoD, muscle-specific HLH protein (Li<br />
et al.), 676-689<br />
Myogenic differentiation, inhibition of<br />
by adenovirus Ela protein<br />
(Braun et al.), 888-902<br />
Myogenin, muscle-specific HLH protein<br />
(Li et al.), 676--689<br />
Myxococcus xanthus, csgA expression<br />
entrains development {Li et al.),<br />
401--410<br />
GENES & DEVELOPMENT 2679
N<br />
N-myc<br />
gene<br />
function of during mouse embryo-<br />
genesis and regulatory interac-<br />
tion with c-myc (Stanton et al.),<br />
2235-2247<br />
physiological function distinct from<br />
other myc genes (Charron et<br />
al.), 2248-2257<br />
role in mouse lung development<br />
(Moens et al.), 691-704<br />
see also myc gene<br />
N4. See also coliphage N4<br />
Negative regulation, by c-Myb carboxy-<br />
terminal element (Dubendorff<br />
et al.), 2524-2535<br />
Nervous system, regulation of Hox ex-<br />
pression (Westerfield et al.),<br />
591-598<br />
Neural<br />
precursor cells, Drosophila (Bier et al.),<br />
2137-2151<br />
tube, dorsoventral polarity and<br />
chicken ld gene products<br />
(Trumpp et al.), 14-28<br />
Neurogenesis (Holmgren and Engel),<br />
161-165 (meeting review)<br />
Drosophila, role of spitz gene (Rut-<br />
ledge et al.}, 1503-1507<br />
Neurogenic genes, Drosophila SOP cell<br />
fate, interaction with Hairless<br />
(H) gene (Bang and Posakony),<br />
1752-1769<br />
Neurospora crassa<br />
bli-7 gene is structural eas gene, en-<br />
codes major rodlet protein (Lau-<br />
ter et al.), 2373-2381<br />
clock-controlled gene ccg-2 allelic to<br />
eas gene (Bell-Pedersen et al.),<br />
2382-2394<br />
sporulation pathways, con gene ex-<br />
pression (Springer and Yanof-<br />
sky), 1052-1057<br />
NF-KB transcription factor<br />
I-Rel inhibits activity {Ruben et al.),<br />
730-744<br />
pS0 and p65 subunits, independent<br />
modes of activation (Fujita et<br />
al.), 775-787<br />
pS0 subunit {Kretzschmar et al.), 761-<br />
774<br />
NF-KB, NLS/IKB interaction (Beg et al.),<br />
1899-1913<br />
Non-AUG initiation, translational acti-<br />
vataion of c-myc (Hann et al.),<br />
1229-1240<br />
Nonessential genes, Drosophila zeste ac-<br />
tivates Ubx transcription<br />
(Laney and Biggin), 1531-1541<br />
Nonsense mutations, MVM RNA, inhi-<br />
bition of splicing (Naeger et al.),<br />
1107-1119<br />
NS1 protein, influenza virus regulates<br />
2680 GENES & DEVELOPMENT<br />
nuclear export of RNA (Alonso-<br />
Caplen et al.), 255--267<br />
Nuclear<br />
hormone receptors, RARs and RXRs<br />
(Mangelsdorf et al.}, 329-344<br />
import, U3 snRNA, molecular signals<br />
for (Baserga et al.), 1120-1130<br />
localization, of Max protein (Prender-<br />
gast et al.), 2429-2439<br />
localization sequences (NLS], of<br />
NF-KB, interaction with IKB<br />
(Beg et al.), 1899-1913<br />
protein, CHOP, dominant-negative in-<br />
hibitor of transcription {Ron<br />
and Hbener), 439-453<br />
transport, Drosophila, dorsal protein<br />
{Norris and Manley), 1654-1667<br />
Nucleocytoplasmic transport, influenza<br />
virus mRNA (Alonso-Caplen et<br />
al.), 255-267<br />
Nucleosome positioning, by a2 repressor<br />
and histone H4 (Roth et al.),<br />
411-425<br />
Nucleosomes<br />
inhibit transcription initiation (Lorch<br />
et al.), 2282-2287<br />
yeast, as opposed to telosomes (Wright<br />
et al.), 187-210<br />
Nullo gene, Drosophila cellularization<br />
{Rose and Wiecschaus), 1255-<br />
1268<br />
NusA transcription factor, E. coli S 10 op-<br />
eron, required to promote RNA<br />
polymerase pausing at termina-<br />
tion site (Zengel and Lindahl),<br />
2655-2662<br />
O<br />
Oct-1<br />
homeo domain, VP 16 association, role<br />
of Glu-22 (Lai et al.), 2058-2065<br />
POU domain, HSV, recognition of sur-<br />
face (Pomerantz et al.), 2047-<br />
2057<br />
Oct-2 homeo domain, Glu-22 substitu-<br />
tion confers VP16 associations<br />
{Lai et al.), 2058-2065<br />
Ommatidia development. See Eye devel-<br />
opment<br />
ompA transcript, E. coli, 5'-untranslated<br />
region acts as stabilizer (Emory<br />
et al.), 135-148<br />
Oncogene, myb (Dubendorff et al.),<br />
2524--2535<br />
Oncogenesis (Holmgren and Engel), 161-<br />
165 {meeting review)<br />
Oncogenic conversion, of bZIP protein<br />
Hlf {Hunger et al.), 1608-1620<br />
Oncoproteins<br />
Fos and Jun, activation domain<br />
(Sutherland et al.), 1810-1819<br />
Jun and Fos {Oliviero et al.), 1799-<br />
1809<br />
Myc family (Mukherjee et al.), 1480-<br />
1492<br />
Oogenesis, Drosophila, role of otu<br />
(Steinhauer and Kalfayan), 233-<br />
243<br />
Ovarian development, Drosophila pro-<br />
tein expression from otu (Stein-<br />
hauer and Kalfayan), 233-243<br />
Oxidative stress, E. coli, Dps protects<br />
DNA (Almir6n et al.), 2646-<br />
2654<br />
Oxytricha nova, e~-telomere-binding pro-<br />
tein, (Mitcham et al.), 788-800<br />
P-element splicing, Drosophila, mecha-<br />
nism regulating (Siebel et al.),<br />
1386--1401<br />
p50 subunit, of NF-KB (Kretzschmar et<br />
al.), 761-774<br />
transcription factor (Fujita et al.), 775-<br />
787<br />
p53<br />
gene product, naturally occuring wild-<br />
type DNA-binding element<br />
(Zambetti et al.), 1143-1152<br />
loss of during cell immortalization<br />
(Ulrich et al.), 876-887<br />
protein, site-specific binding of (Bar-<br />
gonetti et al.), 1886-1898<br />
p65 subunit, of NF-KB transcription fac-<br />
tor (Fujita et al.), 775-787<br />
p67 sRr GaArG-binding factor, interac-<br />
tion with HTLV-1 Taxl, aber-<br />
rant induction of cell growth<br />
(Fujii et al.), 2066-2076<br />
Pair-rule gene, Drosophila<br />
even-skipped {eve), Eve functions as<br />
concentration-dependent mor-<br />
phogen [Manoukian and<br />
Krause}, 1740-1751<br />
ftz (Furukubo-Tokunago et al.), 1082-<br />
1096<br />
and proneural gene expression (Skeath<br />
et al.), 2606-2619<br />
Pair-rule<br />
locus, Drosophila, slp (Grossniklaus et<br />
al.), 1030-1051<br />
segmentation gene, Drosophila hairy<br />
{h) (Sasai et al.), 2620-2634<br />
Paired domain transcription factor,<br />
BSAP encoded by Pax-5 gene<br />
(Adams et al.), 1589-1607<br />
Pan-neural genes, Drosophila deadpan<br />
(dpn) encodes HLH protein (Bier<br />
et al.), 2137-2151<br />
Papillomavirus, E2 protein, dimerization<br />
and DNA binding {Prakash et<br />
al.), 105-116<br />
Paramecium prirnaurelia, induction of de-<br />
velopmental mutations (Meyer),<br />
211-222<br />
Parental imprinting, mouse insulin-like<br />
growth factor II (Igf2) (Sasaki et<br />
al.), 1843-1856<br />
Parotid-specific expression, human sali-<br />
vary amylase gene AMY1C<br />
(Ting et al.), 1457-1465
Parvovirus minute virus of mice (MVM),<br />
nonsense mutations inhibit<br />
splicing (Naeger et al.), 1107-<br />
1119<br />
Pattern formation<br />
A. nidulans, stuA gene required<br />
{Miller et al.), 1770-1782<br />
Drosophila<br />
slp genes (Grossniklaus et al.), 1030-<br />
1051<br />
wing imaginal disc (Van Doren et<br />
al.), 2592-2605<br />
vertebrate, mouse limb development<br />
(lackson-Grusby et al.), 29-37<br />
X. laevis gastrula embryos, role of<br />
X//rn-I gene (Taira et al.), 356-<br />
366<br />
Pax-5 gene, encodes paired domain tran-<br />
scription factor BSAP {Adams et<br />
al.), 1589-1607<br />
PEA3, Ets oncogene family, regulatory<br />
role during mouse embryogene-<br />
sis (Xin et al.), 481-496<br />
Peripheral nervous system development,<br />
Drosophila, couch potato (cpo)<br />
gene (Bellen et al.), 2125-2136<br />
Phage T4, td intron (Clyman and Bel-<br />
fort), 1269-1279<br />
Pheromone<br />
response pathway, S. cerevisiae<br />
components order of action (Cairns<br />
et al.), 1305-1318<br />
kinase cascade {Stevenson et al.),<br />
1293-1304<br />
signal transduction pathway, S. cerevi-<br />
siae (Gartner et al.), 1280-1292<br />
Phosphorylation<br />
of FUS3 kinase, S. cerevisiae (Gartner<br />
et al.), 1280-1292<br />
of Max homodimers (Berberich and<br />
Cole), 166-176<br />
and RB gene product (Qin et al.), 953-<br />
964<br />
of RNAP II CTD heptapeptide repeats<br />
(Peterson et al.), 426--438<br />
yeast signal transduction, of STE7 ki-<br />
nase (Cairns et al.), 1305-1318<br />
Photoreceptor, phytochrome A (phyA)<br />
(Stockhaus et al.), 2364-2372<br />
Phytochrome A (phyA), structure/func-<br />
tion relationship, serine-to-ala-<br />
nine substitutions {Stockhaus<br />
et al.), 2364-2372<br />
Pigment cell formation, Drosophila,<br />
dual Bar homeo box genes (Hi-<br />
gashijima et al.), 50--60<br />
PNS. See Peripheral nervous system<br />
Polarity, bacterial chemoreceptor {Alley<br />
et al.), 825-836<br />
Poly(A)<br />
elongation, X. laevis development,<br />
translational control by {Simon<br />
et al.), 2580-2591<br />
nuclease {PAN), yeast tail degradation<br />
{Lowell et al.}, 2088-2099<br />
tail<br />
length, regulates polyadenylation<br />
{Gershon and Moss), 1575-1586<br />
yeast, shortening of by PAN is 3'-<br />
UTR dependent {Lowell et al.),<br />
2088-2099<br />
Polyadenylation<br />
regulated by poly(A) tail length (Ger-<br />
shon and Moss), 1575-1586<br />
X. laevis embryogenesis, identifica-<br />
tion of novel cytoplasmic cis-<br />
acting element {Simon et al.),<br />
2580-2591<br />
Polycomb chromo domain, Drosophila,<br />
reequired for chromatin binding<br />
(Messmer et al.), 1241-1254<br />
Polycomb group (PEG) genes, Droso-<br />
phila, ph and Pc interaction<br />
(DeCamillis et al.), 223-232<br />
polyhorneotic gene (ph), Drosophila, en-<br />
codes chromatin protein (De-<br />
Camillis et al.), 223-232<br />
Polymerase II transcription, stimulated<br />
by acidic activator GAL4-AH<br />
and TFIIA and IID (Wang et al.),<br />
1716-1727<br />
Polyomavirus enhancer, oncogene-re-<br />
sponsive element (Bruder et al.),<br />
545-556<br />
Positive control mutants, of yeast HAP1<br />
activator (Turcotte and Gua-<br />
rente}, 2001-2009<br />
Post-transcriptional regulation, HSV-1<br />
regulatory protein ICP27 (San-<br />
dri-Goldin and Mendoza), 848-<br />
863<br />
POU domain, of Oct-1 (Pomerantz et al.),<br />
2047-2057<br />
and Oct-1 (Lai et al.), 2058-2065<br />
pqp gene, Drosophila zinc finger protein,<br />
oocyte nucleus localization<br />
(S6galat et al.), 1019-1029<br />
Pre-mRNA splicing<br />
shutdown resulting from heat shock<br />
(Utans et al.), 631-641<br />
site-specific cross-linking prior to<br />
{Wyatt et al.), 2542-2553<br />
SR proteins, conserved family (Zahler<br />
et al.}, 837-847<br />
U6 snRNA as catalytic element in<br />
spliceosome (Sawa and Shi-<br />
mura), 244-254<br />
Pre-mRNAs, processing of, role of<br />
Drosophila rpbl gene (Kim et<br />
al.), 2569-2578<br />
Precursor B lymphocytes, IL-7-regulated<br />
myc gene expression {Morrow<br />
et al.), 61-70<br />
Preimplantation mouse<br />
development<br />
gene expression during {Rothstein et<br />
al.), 1190-1201<br />
imprinted genes influence develop-<br />
ment (Rappolee et al.), 939-952<br />
embryos, localization of DNA MTase<br />
{Carlson et al.), 2536--2541<br />
Preinitiation complex (prelC), Droso-<br />
phila, differential regulation of<br />
by UBX and EVE (Johnson and<br />
Krasnow}, 2177-2189<br />
Prepattem, in Drosophila developing eye<br />
(Dickson et al.), 2327-2339<br />
Prespliceosomes, protein components of<br />
(Bennet et al.), 1986-2000<br />
Prions, replication of in transgenic mice<br />
and hamsters (Hecker et al.),<br />
1213--1228<br />
Processivity factor, in vitro, HIV-1 Tat<br />
(Kato et al.), 655-666<br />
Promoter<br />
-binding factors, counteract chroma-<br />
tin-mediated repression (Cros-<br />
ton et al.), 2270--2281<br />
competition, globin gene switching<br />
{Foley and Engel), 730-744<br />
melting, on Drosophila genes in vivo<br />
(Giardina et al.), 2190-2200<br />
trap vectors, ES cells, gene disruption<br />
(yon Melchner et al.), 919-927<br />
Promoter-enhancer<br />
interaction, 13-globin gene, regulation<br />
by GATA-1 (Fong et al.), 521-<br />
532<br />
competition, LCR function and globin<br />
gene switching (Kim et al.),<br />
928-938<br />
Promoters, RNA polymerase II, TFIID<br />
interaction (Colgan and Man-<br />
ley), 304-315<br />
Proneural gene expression, Drosophila<br />
{Skeath et al.), 2606-2619<br />
Protein<br />
export, E. co//, role of heat shock pro-<br />
teins DnaK and DnaJ {Wild et<br />
al.), 1165-1172<br />
kinase, DNA dependent, signal for<br />
phosphorylation (Peterson et<br />
al.), 426--438<br />
kinase A (PKA), down-regulation by<br />
v-Ras and PKC (Gallo et al.),<br />
1621-1630<br />
kinase C (PKC), down-regulates nu-<br />
clear PKA (Gallo et al.), 1621-<br />
1630<br />
phosphatase SIT4, S. cerevisiae late<br />
G~, required for normal accu-<br />
mulation of SWI4 (Fernandez-<br />
Sarabia et al.), 2417-2428<br />
sequestration, Drosophila hsp70<br />
{Feder et al.), 1402-1413<br />
Protein-DNA<br />
complexes, tetramer of Mu trans-<br />
posase {MuA) {Baker and Mi-<br />
zuuchi), 2221-2232<br />
interactions, insulin minienhancer<br />
complex (German et al.), 2165-<br />
2176<br />
Protein-protein interaction<br />
at composite response elements<br />
{Miner and Yamamoto), 2491-<br />
2501<br />
GENES & DEVELOPMENT 2681
and maize anthocyanin pigmentation<br />
pathway (Goff et al.), 864-875<br />
recognition of surface of Oct-1 POU<br />
homeo domain {Pomerantz et<br />
al.), 2047-2057<br />
TBF-TAF complex hSL1 (Jantzen et<br />
al.), 1950-1963<br />
VP16 association with Oct-1 vs Oct-1<br />
(Lai et al.), 2058-2065<br />
Proto-oncogene<br />
N-myc, mouse lung development<br />
(Moens et al.), 691-704<br />
Raf-1, activation by serum, TPA and<br />
Ras (Bruder et al.), 545-556<br />
see also individual genes<br />
Proto-oncogenes<br />
junB and c-jun, fibrosarcoma develop-<br />
ment (Bossy-Wetzel et al.),<br />
2340-2351<br />
see also individual genes<br />
prp20 yeast mutants, defects in mRNA<br />
processing (Forrester et al.),<br />
1914-1926<br />
R<br />
R7 cell development, Drosophila {Dick-<br />
son et al.), 2327-2339<br />
Raf-1, activation by serum, TPA and Ras<br />
{Bruder et al.}, 545-556<br />
Raft culture, production of HPV (Dollard<br />
et al.), 1131-1142<br />
RAPl-interacting factor (RIF1), mediator<br />
for RAP1 (Hardy et al.), 801-814<br />
Ras<br />
cotransformation assays, biphasic ef-<br />
fect of Max on Myc {Prendergast<br />
et al.I, 2429-2439<br />
signaling pathway, and eIF-4E-induced<br />
transformation (Lazaris-Karat-<br />
zas et al.), 1631-1642<br />
Rat<br />
HLH proteins HES-1 and HES-3, struc-<br />
tural homology to Drosophila<br />
hairy and Enhancer of split (Sa-<br />
sai et al.), 2620-2634<br />
insulin I gene, minienhancer complex<br />
(German et al.), 2165-2176<br />
RAT1 yeast gene, mRNA export (Am-<br />
berg et al.), 1173-1189<br />
RBP1, Drosophila RNA-binding protein,<br />
pre-mRNA processing (Kim et<br />
al.), 2569-2578<br />
RecA protein, E. coli, mediates stable<br />
synapsis of homolog DNA (Ad-<br />
zuma), 1679-1694<br />
Recombinases, RecA and UvsX (Clyman<br />
and Belfort), 1269-1279<br />
Recombination pathway, intron mobil-<br />
ity (Clyman and Belfort), 1269-<br />
1279<br />
Redundancy, Drosophila, and regulation<br />
of Ubx and other genes (Laney<br />
and Biggin), 1531-1541<br />
2682 GENES & DEVELOPMENT<br />
Rel<br />
protein<br />
family, I-Rel inhibits NF-KB tran-<br />
scriptional activity (Ruben et<br />
al.), 745-760<br />
DNA-binding activity of (Kerr et al.),<br />
2352-2363<br />
transcription factors, Drosophila dl<br />
morphogen (Isoda et al.),<br />
619-630<br />
Repressor/activator protein 1 {RAP1),<br />
yeast, activity at silencers and<br />
telomeres (Hardy et al.),<br />
801-814<br />
Retinoblastoma<br />
gene (Rb), expression of during immor-<br />
talization (Ulrich et al.),<br />
876-887<br />
susceptibility gene<br />
RB, growth suppression domain<br />
within (Qin et al.), 953-964<br />
RB1, E2F-pRB interaction (Hiebert<br />
et al.), 177-185<br />
Retinoic acid receptor<br />
rAR systems as compared to RXR fam-<br />
ily (Mangelsdorf et al.), 329-344<br />
transcription factor (RARa), role in he-<br />
mopoietic differentiation (Tsai<br />
et al.), 2258-2269<br />
Retrotransposition, and evolution of<br />
gene regulation (Ting et al.),<br />
1457-1465<br />
Retrotransposon Ty3, preferential inser-<br />
tion of {Chalker and Sandm-<br />
eyer), 117-128<br />
Retroviral sequences, required for tissue-<br />
specific expression, human sali-<br />
vary amylase gene (Ting et al.),<br />
1457-1465<br />
Retrovirus, promoter trap vectors<br />
(U3His and U3Neo) (yon Melch-<br />
ner et al.), 919-927<br />
Rev protein of HIV-1, RNA-binding do-<br />
main of (Tiley et al.), 2077-2087<br />
Rex system, bacteriophage lambda, cell<br />
death (Parma et al.), 497-510<br />
rho-dependent termination, and c4 RNA<br />
controlled expression of the ant<br />
gene {Biere et al.), 2409-2416<br />
Rhodobacter capsulatus, cytochrome c<br />
biogenesis (Beckman et al.),<br />
268-283<br />
Rhomboid (rho} expression, Drosophila<br />
embryo, stripes regulated by dl<br />
(Ip et al.), 1728-1739<br />
Ribonuclease, PAN and mRNA degrada-<br />
tion (Lowell et al.), 2088-2099<br />
Ri~bosomal protein L4, E. coli, regulation<br />
of S10 operon (Zengel and Lin-<br />
dahl), 2655-2662<br />
Ribozyme<br />
core, group I introns (Michel et al.),<br />
1373-1385<br />
hairpin, in vitro selection of (Berzal-<br />
Herranz et al.), 129-134<br />
Ring canals. See Cytoplasmic bridges<br />
RNA<br />
-binding<br />
factor, Drosophila RMP1, functional<br />
similarity to human splicing<br />
factor ASf/SF2 (Kim et al.),<br />
2569-2578<br />
motifs, in DAI (Green and<br />
Mathews), 2478-2490<br />
protein, Drosophila cpo shows ho-<br />
mology to (Bellen et al.}, 2125-<br />
2136<br />
cleavage reaction, hairpin ribozyme<br />
{Berzal-Herranz et al.), 129-134<br />
Pol I factor hUBF, activation domains<br />
of {Jantzen et al.), 1950-1963<br />
polymerase, of N4 DNA virus (Mark-<br />
iewicz et al.), 2010-2019<br />
polymerase II<br />
Drosophila, analysis of dTFIIB<br />
(Wampler and Kadonaga}, 1542-<br />
1552<br />
elongation of [Kato et al.), 655--666<br />
heptapeptide repeats, phosphoryla-<br />
tion of (Peterson et al.), 426-438<br />
holo-THID complex {Zhou et al.),<br />
1964-1974<br />
promoters, TATA-TFIID interac-<br />
tions {Colgan and Manley), 304-<br />
315<br />
SII-dependent transcript truncation<br />
(Izban and Luse), 1342-1356<br />
transcription initiation on chroma-<br />
tin templates {Lorch et al.},<br />
2282-2287<br />
transcription termination (Roberts<br />
et al.), 1562-1574<br />
transcriptional antirepression by<br />
GAL4-VP16 (Croston et al.),<br />
2270-2281<br />
polymerase III<br />
transcription, and TH1B-related fac-<br />
tor BRF1 (Colbert and Hahn),<br />
1940-1949<br />
Ty3 integrates within transcription<br />
initiation region (Chalker and<br />
Sandmeyer), 117-128<br />
polymerase pausing<br />
Drosophila genes, promoter melting<br />
(Giardina et al.),2190-2200<br />
hsp70, DNA requirements of (Lee et<br />
al.), 284-295<br />
promoter-proximal, and block to<br />
transcriptional elongation<br />
(Krumm et al.), 2201-2213<br />
processing<br />
RNase E's role in T4 and E. coli<br />
mRNA degradation {Ehrets-<br />
mann et al.), 149-159<br />
RNase MRP RNA, nuclear role of<br />
enzyme {Schmitt and Clayton),<br />
1975-1985<br />
-protein interactions, exon-bridging<br />
model (Hoffman and<br />
Grabowski), 2554-2568<br />
recognition motif (RRM), isolation and<br />
characterization of rpbl Droso-
phila gene (Kim et al.), 2569-<br />
2578<br />
structure, 5'-stem-loop structure sta-<br />
bilizes E. coli mRNA (Emory et<br />
al.), 135-148<br />
trafficking, RatlP/Seplp homology<br />
(Amberg et al.), 1173-1189<br />
-RNA interactions, sunY intron<br />
(Michel et al.), 1373-1385<br />
RNase MRP RNA, yeast/mammal ho-<br />
mology, nuclear role of enzyme<br />
(Schmitt and Clayton), 1975-<br />
1985<br />
Rodlet<br />
layer, N. crassa, ccg-2 gene encodes<br />
hydrophobin required for (Bell-<br />
Pedersen et al.), 2382-2394<br />
protein, N. crassa (Lauter et al.), 2373-<br />
2381<br />
rpoN Caulobacter gene, and normal cell<br />
division (Brun and Shapiro),<br />
2395-2408<br />
rRNA transcription, negative supercoil-<br />
ing and topoisomerase activity<br />
(Schultz et al.), 1332-1341<br />
RuvA-RuvB protein complex, E. coli, in-<br />
teraction with Holliday junc-<br />
tion promotes branch migration<br />
(Iwasaki et al.), 2214--2220<br />
RXR gene family, ligand specificity and<br />
expression (Mangelsdorf et al.),<br />
329-344<br />
S<br />
S phase, S. cerevisiae, role of CLBS-a<br />
novel B cyclin (Epstein and<br />
Cross), 1695-1706<br />
Saccharomyces cerevisiae<br />
Cdc28-dependent transcriptional acti-<br />
vation (Marini and Reed), 557-<br />
567<br />
cyclin-B homologs function in S phase<br />
and in G 2 (Richardson et al.),<br />
2021-2034<br />
mitochondrial genome maintenance<br />
gene (Jones and Fangman), 380-<br />
389<br />
pheromone response pathway, kinase<br />
cascade (Stevenson et al.), 1293-<br />
1304<br />
prp20 mutation, defects in mRNA pro-<br />
cessing (Forrester et al.), 1914-<br />
1926<br />
RAT1 gene, mRNA export (Amberg et<br />
al.), 1173-1189<br />
RNA levels of G1 cyclins (Fernandez-<br />
Sarabia et al.), 2417-2428<br />
RNase MRP RNA, mammalian ho-<br />
mology (Schmitt and Clayton),<br />
1975-1985<br />
S phase, role of CLB5-a novel B cyclin<br />
(Epstein and Cross), 1695-1706<br />
see also yeast<br />
signal transduction, phosphorylation<br />
of FUS3 kinase {Gartner et al.),<br />
1280-1292<br />
spindle pole body and microtubule<br />
function (Page and Snyder),<br />
1414-1429<br />
telomeres, assume non-nucleosomal<br />
chromatin structure (Wright et<br />
al.), 187-210<br />
telomeric and subtelomeric chromatin<br />
(Wright et al.), 187-210<br />
3' splice site selection (Frank and<br />
Guthrie), 2112-2124<br />
transcription, SPT3 interaction with<br />
TFIID (Eisenmann et al.), 1319-<br />
1331<br />
transcriptional activators, SNF pro-<br />
teins, GAL4, and Bicoid (Lau-<br />
rent and Carlson), 1707-1715<br />
translation initiation and UV resis-<br />
tance, role of SSL1 gene product<br />
(Yoon et al.), 2463-2477<br />
Salivary amylase gene human, parotid-<br />
specific expression (Ting et al.),<br />
1457-1465<br />
Scalloped (sd) gene, Drosophila sensory<br />
organ differentiation, evolution-<br />
arily conserved transcription<br />
factor (Campbell et al.),<br />
367-379<br />
Schizosaccharomoyces pore be<br />
checkpoint genes (Enoch et al.), 2035-<br />
2046<br />
nutritional monitoring and cAMP pro-<br />
duction (Isshiki et al.), 2455-<br />
2462<br />
Scrapie prions, replication of (Hecker et<br />
al.), 1213-1228<br />
scute (sc) Drosophila gene<br />
auto-and cross-regulatory activities<br />
antagonized by emc gene (Van<br />
Doren et al.), 2592-2605<br />
controlled by axis patterning genes<br />
(Skeath et al.), 2606-2619<br />
SecB, chaperone, E. coli protein export<br />
(Wild et al.), 1165-1172<br />
Segment polarity gene<br />
en, Drosophila, directly activated by<br />
Eve (Manoukian and Krause),<br />
1740-1751<br />
Drosophila hedgehog {hh), target of en-<br />
grailed (en) regulation (Tabata<br />
et al.), 2635-2645<br />
Segmentation<br />
Drosophila, slp locus (Grossniklaus et<br />
al.), 1030-1051<br />
pair-rule gene eve, Eve functions as<br />
concentration dependent mor-<br />
phogen (Manoukian and<br />
Krause), 1740-1751<br />
Self-splicing, of group I introns (Michel<br />
et al.), 1373-1385<br />
Sensory organ<br />
development, Drosophila<br />
ac, sc, and emc proteins (Van Doren<br />
et al.), 2592-2605<br />
Hairless (H), protein controls SOP<br />
cell fate (Bang and Posakony),<br />
1752-1769<br />
differentiation<br />
Drosophila transcription factor en-<br />
coded by sd (Campbell et al.),<br />
367-379<br />
precursor (SOP) cells, Drosophila PNS<br />
H gene controls cell fate (Bang<br />
and Posakony), 1752-1769<br />
Seplp, yeast, homology to Ratlp (Am-<br />
berg et al.), 1173-1189<br />
Sevenless activity, different response of<br />
Drosophila ommatidial cells to<br />
(Dickson et al.), 2327-2339<br />
Sexual development, Coprinus, A-mat-<br />
ing-type gene complexes (Kfies<br />
et al.), 568-577<br />
r C. flagellum biosynthesis (Brun and<br />
Shapiro), 2395-2408<br />
Signal transduction<br />
pathway<br />
Drosophila, nuclear transport of dor-<br />
sal protein (Norris and Manley),<br />
1654-1667<br />
HTLV-1, Taxi aberrant induction of<br />
cell growth (Fujii et al.), 2066-<br />
2076<br />
intracellular, S. pombe, coupling of<br />
mitosis to completion of DNA<br />
replication (Enoch et al.), 2035-<br />
2046<br />
Ras mediates 4E-induced transfor-<br />
mation (Lazaris-Karatzas et al.),<br />
1631-1642<br />
Dictyostelium, G protein ot subunit<br />
(Hadwiger and Firtel), 38-49<br />
Raf- 1 proto-oncogene activation<br />
(Bruder et al.), 545-556<br />
S. cerevisiae<br />
pheromone response (Cairns et al.),<br />
1305-1318<br />
phosphorylation of FUS3 kinase<br />
(Gartner et al.), 1280-1292<br />
yeast pheromone response (Stevenson<br />
et al.), 1293-1304<br />
Single-stranded DNA-binding<br />
activity, MF3 (Gualberto et al.), 815-<br />
824<br />
protein (SSB), E. coli, required for N4<br />
early transcription (Markiewicz<br />
et al.), 2010-2019<br />
Site-specific<br />
binding, of wild-type p53 protein (Bar-<br />
gonetti et al.), 1886-1898<br />
cross-linking, of mammalian U5 sn-<br />
RNP to 5' splice site (Wyatt et<br />
al.), 2542-2553<br />
snail gene expression, Drosophila meso-<br />
derm, dorsal-twist interaction<br />
(Ip et al.), 1518--1530<br />
SNF proteins, S. cerevisiae, and tran-<br />
scriptional activation (Laurent<br />
and Carlson), 1707-1715<br />
snRNA, U3, nuclear import of (Baserga<br />
et al.), 1120-1130<br />
Somatic inhibition, Drosophila P-ele-<br />
ment pre-mRNA splicing (Sie-<br />
bel et al.), 1386-1401<br />
GENES & DEVELOPMENT 2683
Spindle pole body, S. cerevisiae, genes<br />
involved in (Page and Snyder),<br />
1414-1429<br />
spitz Drosophila gene, encodes putative<br />
EGF-like growth factor (Rut-<br />
ledge et al.), 1503-1507<br />
Splice site selection, 5' splice site com-<br />
petition model (Siebel et al.),<br />
1386-1401<br />
Spliceosome<br />
formation, and heat shock interference<br />
{Utans et al.), 631-641<br />
protein components of (Bennet et al.),<br />
1986-2000<br />
U6 snRNA association with 5'-splice<br />
site of pre-mRNA (Sawa and<br />
Shimura), 244-254<br />
Splicing<br />
defects, cytoplasmic tail, resulting ab-<br />
normalities (Brannan et al.),<br />
1832-1842<br />
factors<br />
human ASF/SF2, Drosophila RNA-<br />
binding protein RBP1 shows<br />
functional similarity to (Kim et<br />
al.), 2569-2578<br />
SLU7, 3' splice site choice in yeast<br />
(Frank and Guthrie), 2112-2124<br />
SR proteins, conserved family<br />
(Zahler et al.), 837-847<br />
inhibition, by nonsense mutations<br />
(Naeger et al.), 1107-1119<br />
mechanism, spliceosome and prespli-<br />
ceosome, protein components<br />
associated with (Bennet et al.),<br />
1986-2000<br />
mitochondrial group I introns {Guo<br />
and Lambowitz), 1357-1372<br />
Spore viability, Dictyoste//um, and dis-<br />
ruption of spiA gene (Richarson<br />
and Loomis), 1058-1070<br />
Sporulation<br />
Dictyoste//um, and disruption of spiA<br />
gene (Richarson and Loomis),<br />
1058-1070<br />
pathways, N. crassa, con gene expres-<br />
sion {Springer and Yanofsky),<br />
1052-1057<br />
SPT3, S. cerevisiae, interaction with<br />
TFIID {Eisenmann et al.), 1319-<br />
1331<br />
SR proteins, pre-mRNA splicing factors,<br />
conserved family (Zahler et al.),<br />
837-847<br />
SSL1 supressor gene, yeast, role in DNA<br />
repair and/or translation initia-<br />
tion {Yoon et al.), 2463-2477<br />
Stalk formation, Caulobacter, role of 0 "54<br />
factor (Brun and Shapiro), 2395-<br />
2408<br />
Starvation, E. co//, DNA-binding protein<br />
Dps (Almir6n et al.), 2646-2654<br />
Stationary phase of E. coli, role of DNA-<br />
binding protein Dps (Almir6n et<br />
al.), 2646-2654<br />
STE7 kinase, dominant STE11 allele po-<br />
2684 GENES & DEVELOPMENT<br />
tentiates phosphorylation<br />
(Cairns et al.), 1305-1318<br />
STEI1 kinase, dominant allele potenti-<br />
ates phosphorylation of STE7<br />
[Cairns et al.), 1305-1318<br />
STE11. See also kinases<br />
Steel factor (SLF1 cytoplasmic tail, splic-<br />
ing defect and developmental<br />
abnormalities {Brannan et al.),<br />
1832-1842<br />
STEII kinase, S. cerevisiae, constitutive<br />
mutants of IStevenson et al./,<br />
1293-1304<br />
Stem-loop structure, stabilizing influ-<br />
ence in E. coli mRNA (Emory et<br />
al.), 135-148<br />
Stunted (stuA) gene, A. nidulans, re-<br />
quired for cell pattern formation<br />
(Miller et al.), 1770-1782<br />
Subtractive hybridization, of cDNA li-<br />
braries (Rothstein et al.), 1190-<br />
1201<br />
sunY intron, bacteriophage T4 (Michel et<br />
al.), 1373-1385<br />
Supercoiling (negativel, yeast rRNA<br />
transcription initiation (Schultz<br />
et al.), 1332-1341<br />
Supercoiling. See also template super-<br />
coiling<br />
SV40 T antigen, inhibits wild-type p53<br />
binding (Bargonetti et al.),<br />
1886-1898<br />
SWI4 RNA accumulation, S. cerevisiae<br />
late G~, SIT4 protein phos-<br />
phatase required for {Fernandez-<br />
Sarabia et al.), 2417-2428<br />
SW15, yeast transcriptional activator<br />
{Dohrmann et al.), 93-104<br />
T<br />
T/E1A-binding domain, the RB 'pocket'<br />
(Qin et al.), 953-964<br />
Tat HIV- 1<br />
in vitro processivity factor (Kato et al.),<br />
655-666<br />
protein, activation domain inter-<br />
changeable with VP16 (Tiley et<br />
al.), 2077-2087<br />
TATA box<br />
-binding<br />
polypeptide {TBP), part of holo-<br />
TFIID complex (Zhou et al.I,<br />
1964-1974<br />
protein complex, TBF-TAT complex<br />
hSL1 (Jantzen et al.), 1950-1963<br />
chick 13-globin gene, interaction with<br />
cGATA-1 (Fong et al.), 521-532<br />
protected from KMnO 4 by TBP com-<br />
ponent of TFIID (Giardina et<br />
al.), 2190-2200<br />
TFIID binding to {Lorch et al.), 2282-<br />
2287<br />
TATA-less promoter, holo-TFIID sup-<br />
ports transcriptional stimula-<br />
tion from (Zhou et al.), 1964-<br />
1974<br />
Tax 1 transcriptional activator and trans-<br />
forming protein, HTLV-1, inter-<br />
action with p67 sv'v causes aber-<br />
rant induction of cell growth<br />
{Fujii et al.I, 2066-2076<br />
TEF-1, homology to TEA domain of<br />
Drosophila sd (Campbell et al.),<br />
367-379<br />
Telomere<br />
-binding protein, MF3 [Gualberto et<br />
al.), 815-824<br />
formation, P. primaure//a genome re-<br />
organization (Meyer), 211-222<br />
structure, RAP1 regulation of (Hardy<br />
et al.}, 801-814<br />
Telomeres, S. cerevisiae, assume non-<br />
nucleosomal chromatin struc-<br />
ture {Wright et al.), 187-210<br />
Telosome, yeast chromosomal DNA, as-<br />
sembled in non-nucleosomal<br />
chromatin structure {Wright et<br />
al.), 187-210<br />
Template supercoiling, role in N4 early<br />
promoter activation {Mark-<br />
iewicz et al.), 2010--2019<br />
Tenascin extracellular matrix protein,<br />
normal development of TN-de-<br />
ficient mice (Saga et al.), 1821-<br />
1831<br />
Termination/attenuation, block to tran-<br />
scriptional elongation in c-myc<br />
gene (Krumm et al.), 2201-2213<br />
TFIIA and IID, assembly of closed com-<br />
plex (Wang et al.), 1716-1727<br />
TFIIB-related factor, BRF 1, involvement<br />
in RNA Pol III transcription<br />
(Colbert and Hahn), 1940-1949<br />
TFIID<br />
binding, to nucleosome, failure to sup-<br />
port vs support of transcription<br />
initiation (Lorch et al.), 2282-<br />
2287<br />
holo--TFIID, supports activation by di-<br />
verse activators and TATA-less<br />
promoter (Zhou et al.), 1964-<br />
1974<br />
interaction with TATA-containing<br />
and TATA-lacking promoters<br />
(Colgan and Marfley), 304-315<br />
S. cerevisiae, SPT3 interaction {Eisen-<br />
mann et al.), 1319-1331<br />
yeast and human, fianctional equiva-<br />
lent of (Kelleher III et al.), 296-<br />
303<br />
TFIIF, transcription elongation factor, in<br />
conjunction with Tat (Kato et<br />
al.), 655-666<br />
3' splice site selection, yeast, mediated<br />
by splicing factor SLU7 (Frank<br />
and Guthrie), 2112-2124<br />
3T3-L 1 preadipocyte differentiation, role<br />
of antisense C/EBP RNA (Lin<br />
and Lanel, 533-544<br />
Tissue specific<br />
diversity, maize B gene and anthocya-
nm production (Radicella et al.),<br />
2152-2164<br />
expression, Adh, conserved regulatory<br />
unit in Drosophila and man<br />
(Falb and Maniatis), 454--465<br />
mechanism, conservation between<br />
Drosophila and man (Abel et<br />
al.), 466-480<br />
Tobacco, transgenic plant system, struc-<br />
ture/function relationship of<br />
phyA (Stockhaus et al.), 2364-<br />
2372<br />
Toll gene, Drosophila, role in regulating<br />
cell localization (Norris and<br />
Manley), 1654-1667<br />
Topoisomerases yeast, inactivation of<br />
and transcription by RNA poly-<br />
merase I (Schultz et al.), 1332-<br />
1341<br />
Tracking, V(D)J recombination {Gauss<br />
and Lieber/, 1553--1561<br />
Transcript cleavage, and elongation fac-<br />
tor SII (Izban and Luse), 1342-<br />
1356<br />
Trans-activation<br />
domain, in FosB but not FosB2 (Wis-<br />
dom et al.), 667-675<br />
ets family members have different<br />
properties (Wasylyk et al.}, 965-<br />
974<br />
HW-1 Tat, mechanism of (Kato et al.),<br />
655-666<br />
Trans-activator<br />
papillomavirus E2 protein (Prakash et<br />
al.), 105-116<br />
Vpl6 and Tat, interchangeable activa-<br />
tion domains (Tiley et al.I,<br />
2077-2087<br />
Transcription<br />
activation<br />
adenovirus Ela protein represses<br />
HLH protein Myf-5 (Braun et<br />
al.), 888-902<br />
domains, of hUBF (Jantzen et al.),<br />
1950-1963<br />
encoded by maize B gene (Goff et<br />
al.), 864-875<br />
HOB motifs of Fos and lun (Suther-<br />
land et al.), 1810-1819<br />
holo-TFIID complex and diverse ac-<br />
tivator domain interaction<br />
(Zhou et al.), 1964-1974<br />
of N4 early promoter by supercoil-<br />
ing and SSB (Markiewicz et al.),<br />
2010-2019<br />
by NF-KB subunits (Fujita et al.),<br />
775-787<br />
repression of by Fos and Jun (Li et<br />
al.), 676-689<br />
S. cerevisiae, SNF proteins function<br />
coordinately with GAL4 and Bi-<br />
cold (Laurent and Carlson),<br />
1707-1715<br />
Saccharomyces G~-specific genes,<br />
cdc28 kinase and passage<br />
through START (Marini and<br />
Reed), 557-567<br />
yeast and human TFIIDs, functional<br />
equivalent of (Kelleher III et al.},<br />
296-303<br />
activators<br />
GAL4 and Bicoid, dependence on<br />
SNF proteins (Laurent and Carl-<br />
son), 1707-1715<br />
SNF and SWI yeast proteins alter<br />
chromatin structure (Hir-<br />
schhom et al.), 2288-2298<br />
antirepression, by GAL4-VP 16<br />
{Croston et al.), 2270-2281<br />
enhancers, models of mechanism of<br />
action (Geyer and Corces),<br />
1865-1873<br />
elongation, blocking of in human<br />
c-myc gene (Krumm et al.),<br />
2201-2213<br />
factor<br />
complex, NF-KB in (Ruben et al.),<br />
730-744<br />
Drosophila, CREB/ATF family (Abel<br />
et al.), 466-480<br />
evolutionary conservation, encoded<br />
by Drosophila sd gene (Camp-<br />
bell et al.), 367-379<br />
IIB {dTFIIB), Drosophila, analysis of<br />
(Wampler and Kadonaga), 1542-<br />
1552<br />
factor NF-KB, NLS/IKB interaction<br />
(Beg et al.), 1899-19t3<br />
paired domain, BSAP (Adams et al.),<br />
1589-1607<br />
RARa, role in hematopoietic differ-<br />
entiation {Tsai et al.l, 2258-<br />
2269<br />
see also E2F transcription factor<br />
factors<br />
C/EBP and LAP, dominant-negative<br />
inhibitor of transcription (Ron<br />
and Habener), 439--453<br />
C/EBP mechanism of action (Milos<br />
and Zaret), 991-1004<br />
junB and c-jun, functional role in fi-<br />
brosarcoma development (Bos-<br />
sy-Wetzel et al.), 2340-2351<br />
muscle-specific {Yu et al.}, 1783-<br />
1798<br />
stage-specific, globin gene (Foley<br />
and Engel), 730-744<br />
initiation, closed complex requiring<br />
acidic activator GAL4-AH, and<br />
TFIIA and IID (Wang et al.),<br />
1716-1727<br />
regulation<br />
Adh gene, conserved regulatory unit<br />
in Drosophila and man (Falb<br />
and Maniatis), 454--465<br />
and composite response elements<br />
(Miner and Yamamoto), 2491-<br />
2501<br />
Drosophila, differential regulation<br />
by homeo domain proteins UBX<br />
and EVE {Johnson and Kras-<br />
now), 2177-2189<br />
Drosophila, TFIID--promoter inter-<br />
action (Colgan and Manley),<br />
304-315<br />
SWl5/HO and ACE2/CTS1, parallel<br />
pathways (Dohrmann et al.),<br />
93-104<br />
repression, Drosophila, by su(Hw)<br />
(Geyer and Corces), 1865-1873<br />
silencing, RAP1-RIF1 involvement<br />
{Hardy et al.), 801-814<br />
termination<br />
E. coli S 10 operon, r-protein L4 and<br />
transcription factor NusA have<br />
separable roles (Zengel and Lin-<br />
dahl), 2655-2662<br />
factor-dependent (Roberts et al.),<br />
1562-1574<br />
negative regulation (Dubendorff et al.),<br />
2524-2535<br />
phosphorylation of RNAP II CTD hep-<br />
tapeptide repeats (Peterson et<br />
al.), 426-438<br />
yeast<br />
rRNA, negative supercoiling and<br />
topoisomerases (Schultz et al.),<br />
1332-1341<br />
TFIID/SPT3 interaction (Eisenmann<br />
et al.), 1319-1331<br />
Transformation<br />
biphasic effect of Max protein on Myc<br />
cotransformation (Prendergast<br />
et al.), 2429-2439<br />
as distinct from immortalization (Ul-<br />
rich et al.), 876-887<br />
by FosB but not FosB2 {Wisdom et al.),<br />
667-675<br />
pathway, Myc/Max compleses<br />
(Mukherjee et al.), 1480-1492<br />
Transforming protein Tax 1, HTLV- 1, in-<br />
teraction with p67 s~ (Fujii et<br />
al.), 2066-2076<br />
Transgenic mice<br />
activated int-3 locus {Jhappen et al.),<br />
345-355<br />
c-myc-bearing (Benvenisty et al.),<br />
2513--2523<br />
effects of TNFa {Cheng et al.), 1444-<br />
1456<br />
entire 70-kb human [3-globin locus in-<br />
troduced in (Stouboulis et al.),<br />
1857-1864<br />
prion replication iHecker et al.), 1213-<br />
1228<br />
Transgenic zebrafish, HOX promoter ac-<br />
tivation (Westerfield et al.),<br />
591-598<br />
Translation initiation, yeast, role of<br />
SSL1 gene product (Yoon et al.),<br />
2463-2477<br />
Translational<br />
activation, of c-myc 1 {Hannet al.),<br />
1229-1240<br />
control<br />
of Drosophila hunchback gene, by<br />
GENES & DEVELOPMENT 2685
cooperation of Pumilio and<br />
Nanos activity (Barker et al.),<br />
2312-2326<br />
of maternal mRNAs (Sall6s et al.),<br />
1202-1212<br />
X. laevis, activation of masked<br />
mRNAs by cytoplasmic poly(A)<br />
elongation (Simon et al.), 2580-<br />
2591<br />
coupling, bacteriophage P1 and P7, c4<br />
RNA controlled expression of<br />
ant gene (Biere et al.}, 2409-<br />
2416<br />
frameshifting, E. coli dnaX gene<br />
(Tsuchihashi and Brown), 511-<br />
519<br />
initiation, internal ribosome binding<br />
(OH et al.), 1643-1653<br />
tRNA genes, yeast, targets for Ty3 inte-<br />
gration (Chalker and Sand-<br />
meyer), 117-128<br />
tRNA, relationship to Group I introns<br />
(Guo and Lambowitz), 1357-<br />
1372<br />
Tumor necrosis factor a (TNFa), effects<br />
of in transgenic mice (Cheng et<br />
al.), 1444-1456<br />
Tumor progression factors, junB and<br />
c-jun (Bossy-Wetzel et al.},<br />
2340-2351<br />
Ty3, integration, RNA polymerase III<br />
transcription initiation region<br />
(Chalker and Sandmeyer), 117-<br />
128<br />
Tyrosine metabolism, lethal albino mice<br />
(Ruppert et al.), 1430-1443<br />
Tyrosyl-tRNA synthetase, binds the in-<br />
tron core (Guo and Lambowitz),<br />
1357-1372<br />
U<br />
U1 snRNA, X. laevis genes, transcrip-<br />
tional activation at MBT (Lund<br />
and Dahlberg}, 1097-1106<br />
U1 snRNP<br />
binding to pseudo and accurate 5'<br />
splice site (Siebel et al.), 1386-<br />
1401<br />
targets splicing factor U2AF65 to 3'<br />
splice site (Hoffman and<br />
Grabowski), 2554-2568<br />
U2AF65 3' splicing factor, interaction<br />
with U1 snRNP (Hoffman and<br />
Grabowski), 2554-2568<br />
U3 snRNA, nuclear import, molecular<br />
signals for (Baserga et al.), 1120-<br />
1130<br />
U4/U6/U5 triple snRNP complex, entry<br />
into spliceosome (Utans et al.),<br />
631-641<br />
U5 snRNP (mammalian,), site-specific<br />
cross-linking to 5' splice site<br />
(Wyatt et al.), 2542-2553<br />
U5 yeast snRNA, SLU4 and SLU7 genes<br />
2686 GENES & DEVELOPMENT<br />
interact with (Frank and Guth-<br />
rie), 2112-2124<br />
U6 snRNA, as catalytic element in spli-<br />
ceosome (Sawa and Shimura),<br />
244--254<br />
Ultrabithorax (Ubx)<br />
Drosophila, homeo domain protein<br />
UBX (Johnson and Krasnow),<br />
2177-2189<br />
promoter activation, by nonessential<br />
zeste gene (Laney and Biggin),<br />
1531-1541<br />
UV<br />
cross-linking, U6 snRNA associated<br />
with 5'-splice site of pre-mRNA<br />
{Sawa and Shimura), 244-254<br />
resistance, yeast, affected by SSL1<br />
gene (Yoon et al.), 2463-2477<br />
V<br />
V(D)J recombination, deletional vs. in-<br />
versional (Gauss and Lieber),<br />
1553-1561<br />
v-Ras, down-regulates nuclear PICA<br />
{Gallo et al.), 1621-1630<br />
Vaccinia virus, poly(A) tail length (Ger-<br />
shon and Moss), 1575-1586<br />
Vector, gene trap pGT4,5 in mouse ES<br />
cells (Skames et al.), 903-918<br />
Vectors, promoter trap, gene disruption<br />
in ES cells (yon Melchner et al.),<br />
919-927<br />
Virion production, in vitro using raft cul-<br />
tures (Dollard et al.), 1131-1142<br />
Viviparous-1 gene, maize seed matura-<br />
tion, activation of the C1 gene<br />
(Hattori et al.), 609-618<br />
VP16<br />
activates transcription from RNA tar-<br />
get (Tiley et al.), 2077-2087<br />
-induced positive control, transferred<br />
from Oct-1 to Oct-2 by amino<br />
acid exchange (Lai et al.), 2058-<br />
2065<br />
protein, and Oct-1 multiprotein com-<br />
plex (C1), protein-protein inter-<br />
actions (Pomerantz et al.),<br />
2047-2057<br />
W<br />
Wing development, Drosophila ap LIM<br />
gene Cohen et al.), 715-729<br />
X<br />
Xenopus laevis<br />
blastopore lip-specific gene, fork head<br />
domain (Dirksen et al.),<br />
599-608<br />
development, poly(A) elongation and<br />
translational activation (Simon<br />
et al.), 2580-2591<br />
LIM domain, homeo box gene XIim-1<br />
(Taira et al.), 356-366<br />
midblastula transition (MBT), tran-<br />
scriptional activation (Lund and<br />
Dahlberg), 1097-1106<br />
Xenopus oocytes, nuclear imprint of U3<br />
snRNA {Baserga et al.), 1120-<br />
1130<br />
Xlim-I homeo box gene, X. laevis LIM<br />
domain (Taira et al.), 356-366<br />
Y<br />
Yeast<br />
deadenylation, 3'-UTR dependent<br />
(Lowell et al.), 2088-2099<br />
GCN4, as probe for oncogenesis by<br />
AP-I transcription factor (Oliv-<br />
iero et al.), 1799-1809<br />
HAP1 activator, cofactor interaction<br />
(Turcotte and Guarente), 2001-<br />
2009<br />
MFA2 gene, deadenylation of tran-<br />
scripts {Muhlard and Parker),<br />
2100-2111<br />
parallel pathways of gene regulation<br />
(Dohrmann et al.), 93-104<br />
pheromone response pathway, compo-<br />
nents order of action (Cairns et<br />
al.), 1305-1318<br />
rRNA transcription, negative super-<br />
coiling and topoisomerase ac-<br />
tivity (Schultz et al.), 1332-<br />
1341<br />
see also Saccharomyces cerevisiae<br />
TFIIB-related factor BRF1, RNA Pol III<br />
transcription (Colbert and<br />
Hahn), 1940-1949<br />
TFIID, functional equivalent of (Kelle-<br />
her III et al.), 296-303<br />
transcription activators, SNF2/SWI2<br />
and SNF5 alter chromatin struc-<br />
ture (Hirschhorn et al.), 2288-<br />
2298<br />
Ty3 targets Pol III-transcribed genes<br />
(Chalker and Sandmeyer), 117-<br />
128<br />
YG023 gene, yeast, repeated motifs sim-<br />
ilar to Drosophila Pumilio<br />
(Barker et al.), 2312-2326<br />
Z<br />
zeste Drosophila gene, and activation of<br />
Ubx promoter (Laney and Big-<br />
gin), 1531-1541<br />
Zinc finger<br />
protein<br />
encoded by Drosophila qpp gene,<br />
oocyte nucleus localization<br />
(S6galat et al.), 1019-1029<br />
Drosophila su(Hw), transcriptional<br />
repression (Geyer and Corces),<br />
1865-1873<br />
region, yeast regulators SW15 and<br />
ACE2 (Dohrmann et al.),<br />
93-104
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