SYNTHESIS ISSUE 1 2019: ANIMAL & US

Research Highlights
Real-time Detection Kit
for Avian Infl uenza –
H9N2
H9N2 is a low pathogenic avian influenza
(LPAI) commonly found in many countries
in Asia, the Middle East, Africa, and Europe.
The virus often goes undetected especially in
countries that do not carry out surveillance.
In addition, waterfowl and migratory birds
harbour the virus without showing any signs
of illness. Some H9N2 strains are also known
to be zoonotic causing respiratory illness in
human and may contribute to emerging humanlethal
viruses such as H5N1, H7N9, and H5N6,
posing a substantial threat to the public health.
Despite H9N2 being an LPAI virus, concurrent infection
with other agents and stressful conditions may amplify
H9N2 infection in chickens causing significant losses to
the poultry producers. H9N2 is a respiratory virus that is
transmitted rapidly in commercial chicken flocks. Risk
assessment and routine surveillance must be carried out
to detect possible early infection and take the appropriate
measures to reduce losses. The present invention provides
a method of simultaneously detecting influenza virus type
A and subtyping of the H9N2 subtype of influenza virus.
The test is robust with the following characteristics;
TEST CHARECTERISTICS
Specimen:
Swab & Tissues
Test Amount:
1 ug of total RNA
Assay time:
5 hours
Specificity:
100% (Compared
to sequencing)
Sensitivity:
Monoplex (10 -5 HAU
Duplex (10 -4 HAU)
Triplex (10 -3 HAU)
Prof. Dr. Abdul Rahman Omar
Inventor
Laboratory of Vaccines and
Immunotherapeutics
Institute of Bioscience
Tel: +603-8947 2111
E-mail: aro@upm.edu.my
Co-Inventor
Prof. Datin Paduka Dato’ Dr. Aini Ideris
Department of Veterinary Clinical Studies
Faculty of Veterinary Medicine
10 | ISSUE 01/2019