10 Most Advanced Medical Imaging Solution Providers

2019 / Vol. 9 / Issue-2 

Advancing Tech 

Applications 

of 3D Printing in 

Healthcare Industry 

Tim Kelley 

Founder & CEO 

10 

Most Advanced 

Medical 

Imaging 

Solution Providers 

NAUTILUS MEDICAL 

Providing an incredible communication platform For medical 

imaging professionals

Editor-in-Chief Pooja M. Bansal 

Senior Editor Anish Miller 

Managing Editor Aishwarya Nawandhar 

Contributing Writer Shambhavi Mhetre, Vishal Muktewar 

Visualiser David King 

Art & Design Head Amol Kamble 

Art & Design Assistant 

Poonam Mahajan 

Co-designer Paul Belin 

Art & Picture Editor 

Business Development Manager 

Marketing Manager 

Business Development Executive 

Asha Bange 

Peter Collins 

Marry D’Souza 

Mark Williams 

Sales Executives John, Sarah, Bill, Amy 

Technical Head Jacob Smile 

Assistant Technical Head Pratiksha Patil 

Technical Consultants David, Robert 

Digital Marketing Manager Alina Sege 

Assistant Digital Marketing Manager 

SME-SMO Executives 

Research Analyst 

Circulation Manager 

Prashant Chevale 

Manoj, Gemson 

Eric Smith 

Tanaji 

September, 2019 

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Editor’s Column 

rtificial Intelligence (AI) has entered almost all the 

Averticals of business, automating and making processes 

more efficient and error-free. Healthcare, and 

specifically the diagnostics industry, is no different. This 

particular niche has welcomed in AI with open arms. While some 

are seeing it for the benefits it brings for the future of all 

mankind, some are worried that it may replace the radiologists, 

taking up their place in the medical imaging segment. However, 

the reality seems to be different. It is seen that the industry is 

developing further with the team work of radiologists and AI. 

In a Symbiotic 

Relationship 

with AI 

Number of patients are treated at the hospitals every day, and a 

large portion of these require to run some diagnostic test or the 

other. The medical imaging department of a hospital, although 

not visible directly to the common people, plays a crucial role in 

every type of treatment and the work of radiologists is never 

ending. With AI is the picture, not only can their load be shared, 

and rightly, but also it gives them time to interact with the patient 

and their clinical colleagues, making the entire process of patient 

management much easy. 

The schedule of radiologists majorly consists of tasks similar to 

the ones that require them to go through hundreds of images in a 

day, looking for any signs of defects in the scans of patients. Not 

only are these monotonous, but also the results generated are not 

accurate as the radiologists have tremendous workload and the 

outcomes need to be speedy. These are the tasks that they may 

not be very happy to do. This is where AI comes in. Integrating 

and automating such processes with the help of AI with ensure 

quick and accurate results and free the times of the radiologists 

for the tasks that require immediate and necessary manual 

attention. 

The need be aware of the rising role and advantages of 

technology and informatics is ever rising in the diagnostic sector. 

Radiologists should keep upgrading their knowledge bank and 

learn to move ahead in sync with the developing technologies. 

Being an effective assistant that AI is, together with the 

radiologists it can form a sustainable team!

COVER S TORY 

08 

NAUTILUS 

M E D I C A L 

Providing an Incredible Communication Platform for 

Medical Imaging Professionals 

ARTICLE 

CXO 

20 30 


Applications of 3D 

Printing in Healthcare 

Industry 

Expert Advice 

What Digital Startups 

Need to Succeed in 

the Healthcare Space?

CONTENTS 

16 

Aidoc 

Rendering Ingenious AI 

Solutions Tailored to 

Transform Radiology 

Arineta 

Transforming Cardiovascular 

Diagnostics with Ingenious 

and Innovative Solutions 

26 

32 

HT BioImaging 

Detecting Cancer 

Beforehand 

Planmed Oy 

A Pioneer in 

Dignostics Focused on 

Battling Breast Cancer 

36

1 

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ADVANCED 

MEDICAL IMAGING 

SOLUTION PROVIDERS 

Game Changers of 

Medical Imaging 

Industry 

Ashift from reactive to proactive care will be a big step for the healthcare industry. In this 

process, diagnostics has a crucial role to play. With improving medical policies and 

advancing medical technologies, the existing imaging procedures are made better and 

new procedures have been invented. Contributing to this transition are the organizations that are 

innovating their way towards an enhanced tomorrow. 

In our issue of “10 Most Advanced Medical Imaging Solution Providers”, we have listed the 

leading companies that are augmenting the clinical imaging niche with their novel solutions. 

On the cover, we have featured Nautilus medical. It provides end-to-end solution for medical and 

tools to enable professionals to lower costs, speed up workflow, all leading to better care for the 

patients. 

Apart from the informative cover story, we have also featured Aidoc, the leading provider of 

Artificial Intelligence solutions that support and enhance the impact of radiologists’ diagnostic 

power, helping them expedite patient treatment; Arineta Ltd., an Israeli company that develops 

and produces innovative cardiovascular imaging solutions; Planmed Oy that develops, 

manufactures and offers advanced medical imaging solutions for mammography, orthopedic and 

maxillofacial imaging; HT BioImaging that aims at saving lives and improving the quality of life 

of the patients suffering from life-threatening diseases; United Imaging Healthcare; Carestream 

Health; EnvoyAI; Lumendi; and RADLogics. 

We have also incorporated an interesting CXO from Tania Martin-Mercado, the Chief 

Technology Officer of YGEIA, and an intriguing article from our in-house editor. 

So, walk through the pages and enjoy a good read!

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NAUTILUS 

M E D I C A L 

Providing an Incredible Communication Platform for 

Medical Imaging Professionals 

We are dedicated to solving the di culties faced by 

the medical imaging space in healthcare by enabling fast, 

accurate, easy, and timely communication and data extraction

Information management in 

medical imaging is a very crucial 

aspect of patient care. Timely and 

fast information delivery, storage of the 

information, securing the data, as well 

as making it accessible to the right 

people at right time will help save a lot 

of money and improve speed to care. 

Taking these concerns into 

consideration, a radiology software 

development company, Nautilus 

Medical, was started with an aim to 

build the company value. Realizing 

that it was not just about building the 

company, but that they had the chance 

to affect healthcare as a whole. The 

company grew less concerned about 

earning profits and more about how it 

can lower healthcare costs, serve the 

community, and ultimately save lives. 

Today, Nautilus Medical provides 

end-to-end solutions for medical 

professionals working with radiology 

or patient information along with many 

more tools to enable professionals to 

lower costs, speed up workflow, which 

leads to better care for the patients. 

Nautilus Medical is focused on 

building a platform for collecting 

critical patient data and images on 

healthcare networks. It converts all file 

types collected into a universal format 

and redistributes that information for 

patients, specialists, and referring 

physicians. Nautilus’s robust platform 

has been beneficial to more than a 

thousand facilities. These include more 

than 30 of the top 50 medical centers – 

Cedar’s Sinai, Harvard, Shriners, 

Cleveland Clinic, Northwestern 

Harvard, Columbia and Cornell 

Medical Centers, New York 

Presbyterian, Barnes-Jewish 

UPENN/UPMC, to name a few. The 

company has recently partnered with 

Samsung’s radiology division to offer a 

multi-featured solution for expansion 

into the market. 

Every customer of Nautilus is treated 

like a high value professional that 

needs to solve mission critical issues 

within their radiology environment. 

The relationships the company creates 

become part of a special group of 

select users of the most thoughtful 

radiology software on the market. 

Nautilus firmly believes, “Being the 

biggest is not important to our 

customers. However, being the best is 

extremely important to our customers.” 

The Spark to the Fire of Nautilus 

Tim Kelley, the Founder and CEO of 

Nautilus Medical, is a soft-spoken 

person with many varied interests, 

including painting, basketball, and 

martial arts. This diverse background 

has given him the perspective on 

product design, ways to approach the 

market, and management of the 

employees. He has always had a 

philosophy, “Start with problems, then 

“ 

With all our 

solutions, we 

aim to lower 

healthcare 

costs, serve 

the community, 

and ultimately 

save lives 

“ 

offer solutions that ease the pain.” And 

so far, it has worked quite well for 

him! 

Being an optimistic person, he brings 

positivity to the company’s 

development and daily progress. Tim’s 

contribution to healthcare started with 

the growth of the first medical disc 

burning systems twenty years ago to 

eliminate x-ray film. Now, he envisions 

eliminating the discs and growing the 

largest secure exchange platform. 

Amongst his employees, he is known 

as a person who can see around corners 

and puts customers first. Tim believes, 

“Revenue is merely a by-product of 

how happy our customers are.” 

Voyaging towards Success 

Tim started Nautilus Medical with a 

team of former senior healthcare 

executives from renowned companies 

such as J&J, BD, McKesson, TDK, 

and Canon. This team wanted more 

control over development and came 

together to build customer-centric 

software from the user perspective. 

Nautilus, thus, began as a value leader 

with only a few key features to aid its 

growth and establish a reputation for 

quality and service. Having launched 

during the financial crisis, the company 

had to change its focus from revenue to 

strategic brand building. Through the 

years, Nautilus has grown to be a brand 

of high reputation with numerous highprofile 

clients. It plans on entering a 

new phase for the consumer driven 

healthcare space with special attention 

to patient services. 

Powerful Platforms 

MatrixRay is the main product offered 

by Nautilus. It is one of the most 

feature rich image and patient 

information platforms, available in the 

healthcare market. It provides various

“ 

Nautilus provides a level of service 

combined with the delivery of feature 

rich and user friendly platforms that 

build long lasting dependence and trust 

services that include storing of data 

and images securely; viewing images 

anywhere and anytime with robust 

FDA viewer; scanning film and 

documents to DICOM; PACS query 

and retrieve; EMR/EHR integration for 

reports, labs, etc; auto storing and auto 

routing studies; converting DICOM or 

Non-DICOM images; burning CDs and 

DVDs with viewers and encrypting if 

needed; importing files and CDs as 

universal DICOM; anonymizing and 

masking patient data; printing any file 

(PFD, Word, web page, document) to 

DICOM; receiving any HL7 data and 

adding it to patient folder; free text 

reporting and optional advanced 

biometric reporting; and clientless 

uploading and exchanging of images 

and information. It allows quick and 

secure sharing of images with patients, 

professionals, and specialists in the 

fastest, most secure way in the market. 

All of this adds up to complete 

flexibility, total security, and problem 

solving that saves money and lives and 

Nautilus provides all of this at the 

lowest cost possible. 

BebeVue is another prominent product 

of Nautilus, which repurposes elements 

of the company’s platform to deliver 

keepsake pre-natal ultrasounds to new 

moms at the point of care. Regulations 

in healthcare kept OB/GYNs from 

giving the respective moms the videos 

of their respective ultrasounds and 

created a billion-dollar boutique 

keepsake ultrasound business. 

Nautilus’ platform takes the clinical 

ultrasound video clips and creates a 

non-diagnostic keepsake video online 

with built in social media connections 

for easy sharing. BebeVue also offers 

the best patient education and a robust 

search directory for the practices. This 

education and keepsake video results 

in lower liability, better compliance, 

higher patient satisfaction, and better 

outcomes for new moms! 

Solving Problems, Improving Care 

Communication issue in the healthcare 

network is a major problem the 

industry faces. It is caused by fractured 

infrastructure, old equipment, outdated 

systems, disparate language protocols, 

and nobody to take responsibility and 

find answers to this problem. The key 

product of Nautilus, MatrixRay can 

take any file formats and make them 

compatible with other systems. This 

ensures that the images can be restored 

in other systems, saving nearly 20% of 

time when the patient gets rescanned 

for the same images resulting in 

tremendous waste of time and 

monetary resources. This platform can 

reduce costs, reduce rescans, speed 

time to care, improve efficiency, reduce 

aggravation, and possibly save more

We start with 

the problems, 

and then 

offer solutions 

that ease 

the pain 

lives, and may be used by any facility 

of any size. 

As healthcare is becoming more 

consumer-driven, Nautilus makes sure 

that patients have more control. Its 

platform doesn’t tie the patient to one 

site’s portal. It instead makes them a 

part of the whole Nautilus matrix of 

sites numbering in the thousands. They 

receive free storage for themselves and 

their family. Using Nautilus’ platform, 

patients can view or share data and 

images with anyone. 

Staying on the Top 

Understanding its customers’ main 

problems and finding ways to best 

address those problems has been 

tantamount to Nautilus Medical’s 

success. Apart from that, the company 

has ensured security, an issue which 

most of the professionals managing 

PHI (Protected Healthcare 

Information) find difficult to tackle. 

Nautilus has built the only private key 

peer to peer exchange and storage 

system. It is considered as the best 

method of protecting data from

“All your 

sensitive 

health 

data 

is safe 

with us 

hackers. Along with security, the 

company has brought in speed and 

ease-of-use in the medical imaging 

space. 

With an easy design process, most 

features of Nautilus’ platform makes 

implementation of processes simple 

and painless. Adding this with the 

affordable prices the company brings it 

at, makes Nautilus the partner of 

choice for the clients. 

Talking about how to move ahead, Tim 

jokingly states, “If we just do a little 

bit every day, eventually the task will 

become completely overwhelming.” 

Notable Achievements 

For its significant contribution to 

healthcare for years and intelligent 

solutions it offers, Nautilus has been 

honored with Red Herring’s Best Startup 

of North America, Chicago’s Top 

100 Innovative Companies, 

HealthCare Tech Outlook’s Best 

Healthcare Solutions Provider, and 

CIO Bulletin’s 10 Best Healthcare 

Companies of 2019 among others.. 

However, the best achievement for the 

company remains the satisfaction of 

fulfilling the promises it has made to 

its clients. “We keep hearing stories 

about how our platform helped in a 

mission critical situation and saved a 

life or sped up the time to care. That’s 

real impact supported by heartfelt 

motivation,” expresses Tim. Nautilus 

has been a trustworthy and loyal 

partner of various high-profile clients 

like Cleveland Clinic, Harvard, etc. 

The feedbacks it has received has been 

the true testament of its success, like “I 

have yet to see any other program have 

tools like this- very impressive”; “It’s 

done everything we need it to do and 

more, it’s been rock solid ”; “BTW, we 

are extremely happy and thankful for 

all of the time and effort that you guys 

have put in for us. I know that on 

occasion, people ask for 

recommendations, feel free to point 

them in my direction. You will get 

nothing but blazingly positive 

responses.” 

Looking into the Future 

Witnessing the social conscience of 

healthcare, Nautilus foresees that 

certain players will emerge for their 

relevance to solving today’s issues. 

Having heard too many stories about 

big pharma, big insurance and labs that 

tainted the healthcare landscape, the 

company believes that there is a 

tremendous opportunity for it across all 

medical disciplines, including 

veterinary, podiatry, ortho, neuro, 

cardiac, etc. Nautilus aims to become a 

standard in healthcare communication.

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Founded in 2016 by three young entrepreneurs with a 

dream to make deep learning applicable in solving 

real life challenges, Aidoc is a radiology AI start-up 

focused on using deep learning to relieve the bottleneck in 

medical image diagnosis. The trio decided to apply their 

skills and expertise in engineering, data science, and 

artificial intelligence to the field of medical imaging on 

understanding the direct impact of AI advancements on the 

radiology workflow to help improve patient outcomes. 

Within a short span of time, Aidoc is, today, serving over 

160 medical centers worldwide, improving radiology 

turnaround times and helping save numerous lives. 

Aidoc is the leading provider of Artificial Intelligence 

solutions that support and enhance the impact of 

radiologists’ diagnostic power, helping them expedite 

patient treatment and improve quality of care. They help 

reduce turnaround time and augment quality and efficiency 

by flagging acute anomalies in real time. These solutions 

analyze medical images directly after the patient is scanned 

and notify the radiologists of cases with suspected findings 

to assist with prioritization of time-sensitive, and potentially 

life-threatening cases. 

Novel Solutions Revolutionizing Diagnostics 

Aidoc’s AI solutions encompass comprehensive coverage of 

time-sensitive pathologies and minimize bandwith spent on 

time-consuming tasks. It has FDA clearance for three of its 

acute solutions that flag intracranial hemorrhages, 

pulmonary embolisms, and cervical spine fractures. These 

AI solutions support radiologist diagnostics helping them 

prioritize life -threatening cases, subsequently improving 

patient care. Aidoc’s solution are the perfect radiologist aid 

- making radiology departments more efficient and accurate 

in their day-to-day work. 

With Aidoc, radiologists also benefit from the state-of-the 

art deep learning technology that is “Always -on”, running 

behind the scenes and allowing them to focus on the 

diagnosis. The company’s healthcare-grade deep learning 

algorithms are based on the large quantities of quality 

annotated data, making its solutions the most 

comprehensive in the field. 

Why Aidoc? 

Aidoc is one of the only radiology AI companies that are 

already delivering clinical value to a significant customer 

base. It claims to be the first company to receive FDA 

clearance for AI-based triage of positive ICH cases for 

radiologists. The Chairman of Radiology at one of the 

company’s leading sites expressed, “You gave me the peace 

of mind that there were no patients with a brain bleed 

waiting for their scans to be read.” 

With Aidoc’s seamless “always-on” approach, every case 

with a detected acute finding can automatically be 

highlighted and elevated to the top of the worklist to reduce 

the turnaround time for the patients, especially in the cases 

where time matters most. It covers medical conditions 

prevalent in all settings- ED/Inpatient/Outpatient, including 

level 1 trauma centers, outpatient imaging centers, and 

more. 

A Mark of Excellence 

Aidoc was recently listed by the ‘Time Magazine’ as one of 

the ‘50 Genius’ companies of 2018. The company’s 

founders are listed on Forbes 30 under 30 lists for both 

Europe and Israel. Additionally, Aidoc has the most 

clearances for using AI to triage patients. 

16 | September 2019 |

Elad Walach 

Co-founder & CEO 

| September 2019 | 17

“ 

Aidoc believes that technology should serve medicine, empowering physicians 

and helping them to be more effective and efcient. Our mission is to make AI 

a standard of care in radiology. 

“ 

The Torch-bearer of Aidoc 

Elad Walach, the Co-Founder and CEO of Aidoc, is an 

expert in AI with visionary business insights in the 

healthcare space. He holds a B.Sc. in Mathematics and 

Physics from the Hebrew University of Jerusalem and has 

published multiple academic papers on deep learning. Elad 

began his career in the elite Israeli Defense Force 

technology program ‘Talpiot’ and then went on to lead the 

AI research in the Israeli Air Force, where he initiated and 

led several teams focused on machine learning and 

computer vision projects. 

Since the inception of Aidoc, Elad has spearheaded the 

company through three rounds of investment and drove the 

commercial availability of three product lines. With the 

support of an incredible team comprising of technology 

experts from the IDF’s prestigious technology units and 

clinical thought-leaders from leading medical institutions, 

Elad has raised the company to the stature it is at today. 

Aidoc has successfully built a technology that helps 

millions get quicker and more efficient patient care. 

Learn, Innovate, Impact 

Aidoc has achieved success with the help for the three core 

values it abides by. 

Continuous Learning: Everything done at Aidoc is based 

upon continuous learning and optimizing to provide the best 

possible solutions to radiologists. 

Innovative: Developing algorithms and receiving 

regulatory clearances at an unmatched space, paving the 

way for future AI innovation in radiology. 

Impactful: Helping over 1M patients/year by providing to 

healthcare-grade AI to leading university hospitals, 

radiology groups, and private institutions. 



Applications of 

Printing 

in Healthcare Industry 

he advancement of 

Ttechnology in the 

healthcare industry 

has led to pretty big 

innovations over the 

years. Today, the industry 

is equipped with 

ingenious technologies 

that are making the lives 

of humans better. One 

such technology that has 

changed and 

revolutionized the 

industry is 3D printing. 

Originally intended to 

create prototypes, from 

digital space to real-world 

objects its list of 

applications has 

transformed the medical 

space. 3D printing has 

brought many thingsto 

life that were previously 

unimaginable. Let's look 

at the numerous 

applications of this 

brilliant technology that 

have enhanced 

healthcare and made 

various processes easier 

and efcient. 


Articial Prosthetics 

Over the years, the traditional prosthetics have been extensively 

used in most of the cases. But not many people can afford 

them. People from rural areas as well as those that are living in 

a warzone have limited access to healthcare, and available 

prosthetics can be pretty expensive for them. In such cases, 3D 

printed prosthetics pose as a better alternative- it can be made in a 

shorter time as well as less cost as opposed to traditional ones. Pieces 

can be forged and created according to the needs such as household 

use, physical activities, driving, etc. Since no two human bodies are 

identical, these new-age prosthetics can be customized differently, from 

the point of their aesthetics, tting, size as per the convenience of the 

patient, and efciency. Its extreme exibility and ability to adapt to 

numerous materials makes it perfect for everything, including, prosthetic 

skin, hearing aid molds, dental, and orthopedic implants. 

Shaping the Learning Environment in Surgery 

Human bodies are unique, our anatomy is the same but still, there 

are many differences we have in severalorgans, say liver. Liver has a 

complex structure of arteries, veins, bile ducts. Any misplaced cut 

while operating on it can lead to drastic results, and sometimes even 

death. To deal with such scenarios, a very prestigious doctor from 

Cleveland Clinic has along with his team put forth the concept of the 

organ models. These dummy models are made with materials that 

would not only resemble the organs but behave in a way that the 

organs do during the surgery. It will help the doctors to devise better 

surgery plans. Also, such 3D printed organ models can help the students 

understand its complexity, practically. As these organs function as if they 

are real, allowing students to perform operations, repeatedly. This 

printing organ model if integrated into hospitals can provide a pragmatic 

experience for students. 


3D Printed Organs 

3D printing has brought many innovations in the industry. 

Not only has the technology provided us with 3D printed 

custom models, prosthetics, skin, but are at a potentialstage 

of being implemented in human bodies by replacing organs 

like kidney, liver, arms, etc. This will help to efciently reducing the waiting list 

for organ donor industry at large. It can be helpful in creating a material that 

can used as a living tissue. To make this a reality, doctors and scientists around 

the world are planning to infuse 3D printers with human cells and are printing 

living tissues. This concept is known as bioprinting. Biomedical engineers can 

print an organ which is then covered with human cells. After being successfully 

grown on plastic or collagen, it can be implanted in the human body where 

the scaffold disintegrates leaving human tissue behind. 

Medications 

After falling ill, we usually go to the doctors and get a 

prescription of tablets. The tablets cost more or less 

depending upon the substance that they are made from. 

Some tablets are a little hard to swallow. By using 3D printing 

technology, the tablets can be made more porous than the 

traditionally manufactured medications, allowing them to 

melt in the mouth. 3D printing also allows to optimize the 

tablets according to patients' needs and the number of dosages specic 

to them. It will also help pharmaceutical companies to custom-print allin-one 

medications based on recommended ndings, lowering costs, 

and improving outcomes. 


Medical Devices 

Since its inception, number of 3D printed medical devices 

has grown massively and steadily. Devices such as 

stethoscope, braces, clamps, and vacuum pumps can be 

developed at a much cheaper cost. Not only that 

Additionally, this technology will allow us to create specic 

tools as per the needs in extreme times and geographical spaces such as 

underserved ares, warzones. This can enhance and help in assisting 

undeveloped or less-priviledged regions of the world. 

Innovation drives any industry forward towards a better, more advanced tomorrow. 

Along with various other high-end technologies, 3D printing has shown great promises 

for the future. Not only will it help the medical students and experts discover new and 

better ways of treatment, but may actually offer a chance to form real organs, that can 

be used for many patients in need. With more in-depth research, this technology may 

help transform health care at another level, subsequently improving the quality of 

living for myriads of people! 

-Vishal Muktewar, Editor 


Arineta 

Transforming Cardiovascular Diagnostics with Ingenious and Innovative Solutions 

Amongst several heart diseases, Coronary Artery 

Disease (CAD) is a leading cause of death and 

disability world-wide. It is said to be the largest 

killer in the US, causing around 450,000 deaths annually. It 

results from atherosclerosis in one or more of the coronary 

arteries, in simpler terms hardening or clogging of arteries 

that supply blood to the heart, leading to accumulation of 

plaque on the arteries walls and, eventually, to obstruction 

to blood flow. 

Typically, the patients at risk for obstructive CAD are 

referred to so-called functional tests such as ECG, Echo or 

SPECT (single-photon emission computed tomography) 

stress test, and if necessary, by invasive diagnostic 

catheterization and Percutaneous Coronary Intervention 

(PCI) or Coronary Artery Bypass Graft (CBAG). However, 

according to the American Heart Association data, as well 

as large scale studies, over 50% of the diagnostic 

catheterizations in the US end up with negative results - no 

significant obstruction. Additionally, diagnostic 

catheterizations are invasive procedures that involve pain, 

fairly high radiation dosage, hospitalization, certain risk and 

cost to the health system. Therefore, there is a need for 

another non-invasive, low dose, efficient, and accurate CAD 

diagnostics. 

Arineta Ltd. is an Israeli company that develops and 

produces innovative cardiovascular imaging solutions. Its 

TM 

flagship product, CardioGraphe , is the world’s first 

dedicated single-heartbeat, whole heart cardiac CT scanner, 

® 

based on the company’s proprietary Stereo CT technology. 

CardioGraphe brings an effective non-invasive solution for 

diagnostics of CAD. Arineta aims to be a company that 

improves the outcomes for patients world-wide through 

better and more advanced healthcare pathways. 

Located in the Caesarea Industrial Park, Caesarea, Israel, 

Arineta is a part of a long tradition of medical imaging 

innovation that began in Israel in the 1970s. Among 

Arineta’s scientists are the inventors of the multi-slice spiral 

CT technology, the cornerstone of CT imaging, and several 

other key technologies. 

The Success Safari 

Established in late 2006, Arineta started as a small team of 

engineers and scientists investigating concepts for a new 

solution for accurate and reliable CAD diagnosis. Until the 

introduction of CardioGraphe by Arineta and GE, there 

were no dedicated cardiac CT scanners in the market. 

Development of the CardioGraphe started in 2012 and by 

2016 the product was undergoing clinical evaluation. 

The CardioGraphe clinical results have shown that a wholeheart, 

single-beat, special-purpose cardiovascular scanner 

greatly improves clinical outcomes. Crisp and accurate 3D 

images of the heart and the coronary arteries are obtained 

routinely in a safe, painless, non-invasive procedure within 

minutes. In particular, CardioGraphe provides diagnostic 

quality results also on hard-to-do patients with highly 

calcified coronaries, high or unstable heart rate and obese 

patients, which other scanners cannot scan successfully. The 

scanner is less costly than other similar performance 

scanners, can fit in a smaller space and has high throughput. 

Based on these successful results, the product was then 

submitted for regulatory clearance and gained permission 

for marketing in the US, Europe, China, and other 

countries. During 2017-2018 the company established its 

manufacturing facility and started serial production of 

CardioGraphe. Today, CardioGraphe is distributed globally 

in cooperation with GE Healthcare. 

A Revolutionary Product 

TM 

CardioGraphe is the first and only dedicated 

cardiovascular CT imager designed to provide 

comprehensive clinical information for diagnosis and 

therapy planning. The product is optimized for imaging the 

entire heart and cardiovascular system at high resolution 

and excellent motion freeze with 140 mm coverage at a 

rotation speed of 0.24 sec per rotation. CardioGraphe uses a 

lower radiation dose than whole-body CT scanners. Further, 

the imaging is based on a single heartbeat as well as the fast 

speed of the scan that reduces contrast volumes and the 


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Dr. Ehud Dafni 

Co-founder and CEO 

need for administration of beta blockers. 

The proprietary Arineta design includes: 

• Unique Stereo CT® technology - Two overlapping x-ray 

beams rotate around the patient in parallel trajectories, 

achieving excellent image quality and wide z-axis 

coverage with no need for two detectors. 

• Focused field-of-view (FOV) - CardioGraphe’s focused 

FOV generates high-resolution images of the area of 

interest, while highly reducing radiation dose to peripheral 

anatomies compared to whole-body CT systems. 

• Advanced iterative reconstruction technology combined 

with Arineta’s unique model based adaptive filtering 

reduces noise and improves low-contrast detectability 

even at low signal levels. 

• Ultra-short gantry geometry that makes efficient use of the 

x-ray sources, allows fast rotation and reduces footprint. 

An Adept Leader 

Dr. Ehud Dafni, the Co-founder and CEO of Arineta, has 

a strong background in medical imaging. He has extensive 

experience in the field of computed tomography, where he 

co-invented multi-slice spiral CT, multi-source spiral CT, 

adaptive dose modulation, Stereo CT and focused Field of 

View with graded resolution detector. Before founding 

Arineta, Dr. Dafni served as the vice president for business 

“ 

We are dedicated 

to providing 

superior innovative 

solutions for 

safe, reliable, 

and cost-effective 

cardiovascular 

diagnostics and 

therapeutics 

“ 


Multiple Applications of CardioGraphe: 

4 One-beat, high-definition, motion-free coronary images 

at any heart rate. 

4 Provides high quality data for optional FFR CT analysis. 

4 Comprehensive cardiac assessment for every patient 

including coronaries, structure, and Left ventricle 

function assessment. 

4 Peripheral vascular imaging, from Circle of Willis, 

carotids to aorta, main pulmonary, renal, to femoral 

arteries. 

4 TAVR, Mitral, LAA, and other procedure planning with 

dedicated protocols. 

development at CMT Medical Technologies and CEO of 

CardioWatch Ltd. Previously, he worked at Philips Medical 

Systems in Israel and the US, at Picker 

International/Marconi Medical Systems, Cleveland, Ohio, 

and at Elscint Ltd., Haifa, Israel. He was also a faculty 

member at the Weizmann Institute of Science, Rehovot, 

Israel, and at the University of Rochester, NY. 

With such vast experience and rich skill set, Dr. Dafni has 

led Arineta impressively to greater heights of success and 

continues to do so. “Arineta is proud to provide the 

CardioGraphe, the world’s first cardiac dedicated CT 

imaging system. Our goal is to deliver earlier, safer and 

more accurate non-invasive diagnosis of heart diseases for 

millions of patients,” he asserts. 

Towards a Bigger Tomorrow 

Arineta does not plan on stopping at its first product. While 

receiving feedback from users and responding with 

enhancements, the company develops additional products in 

the cardiovascular imaging space. It intends to remain a 

leading provider of innovative medical imaging products. 

Believing in the numerous capabilities that Artificial 

Intelligence has to offer to the aspects of medical imaging, 

Arineta seeks to use AI in signal processing, image 

processing and diagnostic support applications. 

Additionally, it focuses on development of more complex, 

iterative, and adaptive image reconstruction algorithms for 

faster workflow, better image quality, and reduced radiation 

dose. 


Expert Advice 

ABOUT THE AUTHOR 

Tania Martin-Mercado, PhD, 

is the Chief Technology 

Officer of YGEIA, a digital 

healthcare company focused 

on home healthcare and 

chronic disease 

management. She holds 

various degrees in IT, 

healthcare, as well as 

biotechnology and is 

seasoned with a lot of 

experience at various 

prestigious posts throughout 

the years. Being a curious soul 

and always been fascinated 

with technology, Tania has 

been a part of various 

healthcare innovations. 

Tania Martin-Mercado 


WHAT DIGITAL STARTUPS 

NEED TO SUCCEED IN THE 

HEALTHCARE SPACE? 

e hear a lot of buzz in the 

Windustry and in the 

marketplace about the 

latest in digital healthcare. From 

artificial intelligence, machine 

learning, remote patient monitoring 

and wearable technology to home 

monitoring and data, data, data – 

digital healthcare has morphed into one 

of the most transformative healthcare 

trends. 

While this is one of the most exciting 

times to be in the digital healthcare 

market, startups focused on this space 

need to make sure their product and 

service have three-fold impact: 

Improved patient outcomes, reduced 

cost of delivery, and quality of care. 

Cost, quality and patient experience 

often go unnoticed or ignored in favor 

of technical functionality. The latest 

and greatest digital healthcare 

technology will fail if the patients 

don’t understand how to use it, 

providers can’t implement it into their 

workflow, and payors won’t reimburse 

for its use. 

By starting with a patient-centered 

focus, digital startups will find they 

may need to slow down and get a 

better understanding of the healthcare 

industry, which operates differently 

than the tech world. There are more 

stakeholders in healthcare that need 

consideration: doctors, patients, 

insurers, regulators; each of these 

stakeholders holds a unique 

perspective on the technology being 

adopted. Healthcare is complex 

because patients are complex. As 

digital startups focus on one area, such 

as a particular disease, they may 

stumble onto the multiple factors that 

contribute to that disease, what insurers 

do and don’t cover related to that 

disease and its symptoms, and more 

variables that directly or indirectly 

affect their product or service. The 

development of a product or service 

requires research into clinical practice, 

medical study, patient and doctor 

interviews, and several focus groups. 

Digital healthcare startups need to have 

patience – something that is 

unattractive to some investors, causing 

digital healthcare startups to rush into 

product development too quickly. 

Instead, involving key stakeholders 

early in the development process and 

fully understanding the concerns and 

perspective will allow these startups to 

impact the healthcare space where it 

matters most – patient care. 

The Medical Futurist published a 

fantastic article earlier this year that 

highlights why healthcare startups fail. 

Forgetting about the patient, not 

including the provider, difficulty 

creating clinical value and 

overclaiming what the technology can 

do area just a few of areas discussed in 

this article. 

Another area often overlooked by 

digital healthcare startups is the need to 

integrate. Healthcare data is massive, 

and there is no “central repository” to 

draw from. By understanding and 

embracing the need for shared services, 

integration with other startups or 

providers in the healthcare industry can 

foster innovation and better meet 

patient need or demand. Instead 

startups may focus on siloed solutions 

that make it difficult for providers to 

implement into their practice, thus not 

offering value to the patient. By 

understanding how patient data is 

viewed from a provider and payor 

perspective, digital healthcare startups 

will find out how their product or 

service will be most useful. 

This is such an exciting time to be in 

the healthcare space. The satisfaction 

of making a positive impact in 

communities by improving patient care 

is why many startups dive into the 

healthcare space. By taking a few of 

these points into consideration, digital 

healthcare startups will find their 

endeavors bearing fruit. 


1 

MOST 

ADVANCED 



HT BioImaging 

DETECTING CANCER BEFOREHAND 

Today, people are prone to numerous health issues 

and cancer is one of the major problems which has 

been growing at an alarming rate. Most of the 

people are unaware of what type of health condition they 

are living with. 

Various research has shown that early cancer detection can 

be helpful in saving the life of the person, in the cases 

where it would be a thin possibility otherwise. When the 

cancer is detected early, the prognosis and prospects of 

successful treatment are significantly improved. Yet, for 

some types of cancer and other deadly diseases, there is no 

current early detection examination. Or if there is, it is not 

conducted as a routine test or is not affordable. Additionally, 

current screening methods are problematic due to relatively 

high erroneous results. Furthermore, the time span for 

which the patients need to wait for the tests and their result 

may cost them their lives. 

In order to help people detect cancer at an early stage, HT 

BioImaging came into existence. It will aim at saving lives 

and improve the quality of life of the patients suffering from 

life-threatening diseases. For providing this, the company 

has developed a platform for cancer detection that is based 

on a noninvasive, safe, accessible, and highly accurate 

system. With this system, initial screening and cancer 

imaging will become a simple and affordable process, 

easily accessible to the community. Its platform technology 

provides real-time results that will enable physicians to 

decide on the spot if additional, more expensive and 

high-risk testing is necessary. 

Prominent Personalities of HT BioImaging 

Shani Toledano is the Co-founder & CEO of HT 

BioImaging. She has a B.Sc. in Mechanical Engineering 

specialized in heat transfer and thermodynamics. Working 

for 11 years in the tech, defense, and aviation industry as a 

developer, system engineer, and R&D team leader, she has 

gained immense experience. 

Gideon Barak, the Co-founder & Chairman of HT 

BioImaging, is a serial entrepreneur with 10 exit records. 

He has held leading positions in several companies 

including co-founder and CEO of DSP Communications 

(NASDAQ: DSPC), acquired by Intel in 1999 for $1.6 

billion, and Founder and Chairman of Envara and Butterfly 

VLSI, acquired by Intel and Texas Instruments in 2004 and 

2000, respectively. 

The journey of the company started a few years ago when 

Shani’s father’s chest x-ray test accidentally found a 5 cm 

tumor in the place where he was experiencing chest pain. 

Unfortunately, the cancer was in its late stage and within 9 

months, her father passed away. She then started reading 

and understanding the occurrence of cancer. Shani used her 

knowledge gained from her education in heat transfer and 

thermodynamics to establish HT BioImaging with the help 

of her professor of thermodynamics and her father’s 

oncologist. With the help of Barak and his entrepreneur 

skills, she started this essential company. 

Essential Products and Services 

HT BioImaging is now introducing its first application - 

HTOScan. This application is a disruptive next-generation 

oral scanner for the detection of cancer and pre-cancer 

based on its own breakthrough patented medical imaging 

technology. The technology uses thermal diffusion to record 

the heat dissipation in the tissue which enables it to identify 

the observed discontinuity in the tissue as cancerous with 

an accuracy of 95%. It differentiates the cancerous cells 


Shani Toledano, Co-founder & CEO 

We are commi ed to save lives and improve the 

life quality of deadliest diseased patients 

-Shani Toledano 


from normal cells by exploiting their unique heat-flow 

properties. HTOScan does all these things: 1. High 

Accuracy and Location Coverage; 2. Non-Invasive and 

Low Risk; 3. Analysis and Results delivered in Real-Time; 

and 4. Detect malignant & premalignant lesions with no 

visual symptoms (submucosal lesions). 

The detection process based on the fact that density of the 

cancerous and precancerous cells is higher than that of 

normal cells, their shape is different, and their nuclei are 

enlarged. This results in the differences that cause a 

fundamental change in the thermal properties of the tissue 

(blood flow, heat capacity, conductivity and metabolism). 

The functional imaging technique is used for testing the 

response of the tissues to the thermal excitation over a short 

period of time. Therefore, it can be used to distinguish 

between cancer and other pathologies such as pre-cancer, 

benign growths or necrosis as a result of cancer treatment 

and surgical removal. 

The operating process of HTOScan is based on the principle 

which involves short, safe, and focused heating followed by 

tracking the heat expansion and absorption in the tissue. 

The system is a combination of a cloud-based database 

where the data is stored. Further, the data is processed using 

a unique proprietary analysis algorithm, using signal 

analysis, machine learning and more artificial intelligence 

techniques of image pattern recognition based on an evergrowing 

bank of data. 

Future Goals 

HT BioImaging has a roadmap for the next 2 years for the 

growth of the company. It plans on the validation of 300 

patients through an algorithm along with oral device 

marketing version, pivotal trial, CE-Mark + initial 

commercialization in Europe, and FDA Approval + initial 

commercialization in US. 


1 

MOST 

ADVANCED 



Mr. Jan Moed 

Managing Director 


Planmed Oy 

A Pioneer in Diagnostics Focused on Battling Breast Cancer 

Around 2.1 million women around the world are 

reported to be suffering from breast cancer 

according to the WHO, making it the most 

common type of cancer found in women. Not only has the 

disease spread substantially but has also proved to be most 

fatal form of cancer, causing the demise of over 627,000 

women in 2018. Additionally, these numbers are reported to 

be increasing with every passing day. Diagnosis and 

screening of breast cancer in the early stages has become 

pivotal to bring down the number of women affected by the 

disease. There are various solutions available to enable this; 

however the shortage of resources has made it difficult and 

most of the women are diagnosed in later stages, increasing 

the fatality rate. One of the leading companies in the world 

that is fighting against breast cancer by offering 

comprehensive product portfolio in the field of 

mammography is Planmed Oy. It has been battling this 

deadly disease through sophisticated technology, wellknown 

imaging performance, user friendliness and good 

ergonomics. 

Established in 1987 in Helsinki, Finland, Planmed Oy 

develops, manufactures and offers advanced medical 

imaging solutions for mammography, orthopedic and 

maxillofacial imaging. It is an integral part of the Finnish 

Family owned Planmeca Group, the largest privately owned 

dental manufacturing company in the world. 

Planmed Oy has always ensured to stay a step ahead of its 

contemporaries owing to its in-house researchers and 

designers dedicated to innovation and adaption of emerging 

technologies. The company has developed the advanced 

and unique 3D imaging of extremities and head & neck and 

is on its way to becoming the forerunner in 3D orthopedic 

and maxillofacial imaging in the industry. 

The story of Planmed Oy dates back to 1971, when its 

parent compant, Planmeca Oy, was incepted. Today, 

Planmed Oy’s medical imaging solutions can be found in 

more than 80 countries worldwide and the company is 

continuously expanding, entering new markets and 

providing the latest technology to leading clinics and 

hospitals around the world. 

Momentous Benchmarks 

Although, Planmeca is a dental company at its foundation, 

it expanded into the medical diagnostic field in 1989 though 

its subsidiary company- Planmed Oy. In the same year of its 

establishment, Planmed Oy announced its first product, 

Planmed Sophie Mammography, at the RSNA meeting. 

Many of the units installed back then by the company are 

still in use today. This indicates the robustness, high quality 

and well-made design- all the characteristics the company is 

known for even now. 

In 1991, the company launched Planmed Cytoguide, a 

biopsy needle guidance system for stereotactic breast 

biopsy, and a year later, it brought the unit for mobile 

mammography to the market, known as Planmed Sophie 

Mobile. Towards the start of the next decade, Planmed Oy 

was developing another one of its remarkable products, the 

MaxView Breast Positioning System. This system 

maximizes the field of view in mammography by enabling 

the detection of even the smallest lesions even closer to the 

chest wall that otherwise might go undetected. Further, in 

2005, the company delivered the first fully digital 

mammography unit called Planmed Nuance, along with 

DigiGuide for digital stereotactics and Planmed CAD for 

computer-aided detection. 

In the year 2010, Planmed Oy expandedits medical 

portfolio into revolutionary new concept for low dose 3D 

® 

orthopedic imaging by launching Planmed Verity . 

Furthermore, the company introduced its award-winning 

digital mammography system with Digital Breast 

Tomosynthesis capability, Planmed Clarity Product Family, 

in 2016, and extended mammography product portfolio 

again in 2018 by launching Clarity S Digital 


“We want to aid in better patient care through pioneering 

health care solutions that improve the daily workow of 

medical professionals around the world” 

Mammography. The innovations and simultaneously the 

growth of the company continues. 

Substantial Product Portfolio 

Planmed Oy has two different product lines- mammograpy 

and orthopedic and head and neck imaging. More than 10% 

of the company’s revenue is used as R&D expenseand it has 

developed everything in-house with a sound know-how and 

advance technologies to take the medical imaging industry 

a step ahead. All of Planmed Oy’s products have been 

designed with the collaboration of users and special 

attention is given to the ergonomics, for both- the users and 

the patients. 

As seen earlier, Planmed Clarity Mammography systems 

have been developed gradually, through the years, and they 

provide outstanding image quality and enable a fast and 

reliable workflow in all situations – from screenings to 

diagnostic imaging to biopsy procedures. This group 

incorporates Planmed Clarity 3D and Planmed Clarity 2D 

digital mammography system along with Planmed 

Clarity Flow touch control with dual touchscreens. 

Additionally, the company ensures positive patient 

experience through an impressive design to reduce patient 

anxiety. It encourages increasing number of women to 

participate in breast cancer screenings. 

In orthopedic imaging, Planmed Oy was the first company 

to bring the CBCT (ConeBeam Computed Tomography) for 

extremities to the industry. This 3D technology by Planmed 

is widely used in maxillofacial and dental imaging and is 

highly suitable for bony structures. Adding to this is the 

Planmed Verity, a revolutionary system that can provide 

images of the foot and ankle under a natural load. 

The Prodigious Leaders 

Mr Heikki Kyöstilä, the Founder and President of 

Planmeca Group, is a passionate entrepreneur and a handson 

leader. His presence has been a rich source of inspiration 

for all those working at the company. Talking about the 

ingredients to Planmed Oy’s recipe of success, Heikki says, 

“Strong commitment to building customer relationships and 

passion for innovation guide everything we do. They give us 

the focus to consistently develop revolutionary technology 

and gain a deep understanding of the needs of dental and 

healthcare professionals. These values have led us to the 

forefront of our industry.” 

Another pair of hands, which have crafted the successful 

story of Planmed Oy, are that of Mr. Jan Moed, the 

Managing Director of Planmed Oy. He has an extensive 

experience in the healthcare space and has held various 

reputable positions in Planmeca over last 20 years. With his 

great professional knowledge and enriched experience in 

health technology, he has significantly contributed towards 

the health tech innovations that have the power to change 

the world. He is also the Vice Member of the Board of the 

Finnish Health Technology Association. Jan is a true change 

maker and visionary leader in the health care industry. 

Awards and Accolades 

For its innovative products, dedication and hard work, 

Planmed Oy has been honored with several awards, 

including Fennia Prize 2017 and Red Dot 2016 Design 

Award for Planmed Clarity Mammography unit. The 

company has also received Fennia Prize 2012, MDEA 2012 

Gold and Best in Show and Red Dot 2012 Design Award for 

Planmed Verity orthopedic imaging equipment. 

Future Roadmap 

For the coming future, Planmed Oy plans to continue on the 

path it started, developing more advanced medical devices 

by utilizing its groundbreaking in-house algorithms. It aims 

to produce affordable high-tech medical equipment that will 

save lives.

10 Most Advanced Medical Imaging Solution Providers

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