Turkish Journal of Hematology Volume: 37 Issue: 1 / 2020

Turk J Hematol 2020;37:57-76
LETTERS TO THE EDITOR
Financial Disclosure: The authors declared that this study
received no financial support.
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Supplemental Table 1. Definition of thromboelastographic parameters [1,2].
Definition of parameter Indicated by increased values Indicated by decreased values
R (min)
(reaction time)
K (min)
(clot kinetics)
Alpha angle
(degree)
(clot kinetics)
MA (mm)
(maximum
amplitude)
CI (coagulation
index)
Maximum lysis
(LY30)
(%)
CI: Coagulation index; LY: Maximum lysis.
The time elapsed between the placement
of first blood sample in the device and
formation of fibrin (2 mm); associated
with plasma coagulation and inhibitor
activity
The time elapsed between the R time and
the time in which clot reaches 20 mm
of amplitude; associated with kinetics of
clot formation and measures the speed
of clot to attain a certain strength
Measures the speed of clot
polymerization; associated with
strengthening of clot
A direct function representing
maximum dynamic property of fibrin
and thrombocyte binding; associated
with thrombocyte function rather than
fibrinogen; denotes strength of fibrin
clot
Found by calculating linear indexes of R,
K, MA, and α angle values
Denotes the decline of the 30th minute
of amplitude after MA, as percentage;
indicates the degree of fibrinolysis and is
associated with clot stability
Factor deficiency
Anticoagulant therapy
Low fibrinogen level
Low thrombocyte count
Factor XIII deficiency
Low fibrinogen level
Thrombocytopenia
Insufficiency in thrombocyte functions
Use of heparin as anticoagulant therapy
Hypercoagulation
Hypercoagulation
If hypercoagulable status originates from
plasma (enzymatic hypercoagulability), R time is
decreased more than K time; if hypercoagulable
status originates from thrombocytes, both R
and K times are decreased
Values greater than +3 indicate
hypercoagulation
Values greater than 7.5% indicate increased
fibrinolysis
Hypercoagulation
Hypercoagulation
Major increase in fibrinogen,
and increased thrombocyte
function to a lesser extent
Factor deficiency
Fibrinogen impairment
Thrombocytopenia
Increased fibrinolysis
Thrombocytopenia
Thrombocytopathia
Hypofibrinogenemia
Values less than -3 indicate
hypocoagulation
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