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THE VACCINE<br />
PROMISE<br />
Excitement builds up as a vaccine<br />
shot to prevent the deadly SARS-<br />
CoV-2 infection becomes real<br />
Following the release of early data from<br />
phase III trials on 9 November, vaccine<br />
makers Pfizer and BioNTech are seeking<br />
regulatory permission to commercialise<br />
their vaccine under emergency-use<br />
authorisation. Moderna, which has also<br />
released early clinical trial data showing<br />
that its vaccine is nearly 95% effective, is<br />
in the process of filing for EUA. Countries<br />
like UK are already set off the registration<br />
procedures to make the vaccine available to<br />
the health care staff at the earliest.<br />
None of these vaccine data, however, has<br />
yet been peer-reviewed.<br />
MODERNA<br />
Vaccine type: messenger RNA<br />
Efficacy: 94%<br />
(spurs immune response<br />
in older adults)<br />
Dosage:<br />
Duration:<br />
Price:<br />
Storage:<br />
Safety:<br />
2 doses<br />
28 days apart<br />
$25 per dose<br />
Remains stable in<br />
conventional refrigerators<br />
for a month and ordinary<br />
freezers for six months<br />
No major adverse drug<br />
event (ADE) reported<br />
during trials<br />
PFIZER/BIONTECH<br />
Vaccine type: messenger RNA<br />
Efficacy:<br />
92%<br />
Dosage:<br />
Duration:<br />
Price:<br />
Storage:<br />
Safety:<br />
2 doses<br />
28 days apart<br />
$15 per dose<br />
−70 °C before delivery<br />
No major ADE reported<br />
during trials<br />
24 / FUTURE MEDICINE / <strong>December</strong> <strong>2020</strong>