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FM December 2020 digital P

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THE VACCINE<br />

PROMISE<br />

Excitement builds up as a vaccine<br />

shot to prevent the deadly SARS-<br />

CoV-2 infection becomes real<br />

Following the release of early data from<br />

phase III trials on 9 November, vaccine<br />

makers Pfizer and BioNTech are seeking<br />

regulatory permission to commercialise<br />

their vaccine under emergency-use<br />

authorisation. Moderna, which has also<br />

released early clinical trial data showing<br />

that its vaccine is nearly 95% effective, is<br />

in the process of filing for EUA. Countries<br />

like UK are already set off the registration<br />

procedures to make the vaccine available to<br />

the health care staff at the earliest.<br />

None of these vaccine data, however, has<br />

yet been peer-reviewed.<br />

MODERNA<br />

Vaccine type: messenger RNA<br />

Efficacy: 94%<br />

(spurs immune response<br />

in older adults)<br />

Dosage:<br />

Duration:<br />

Price:<br />

Storage:<br />

Safety:<br />

2 doses<br />

28 days apart<br />

$25 per dose<br />

Remains stable in<br />

conventional refrigerators<br />

for a month and ordinary<br />

freezers for six months<br />

No major adverse drug<br />

event (ADE) reported<br />

during trials<br />

PFIZER/BIONTECH<br />

Vaccine type: messenger RNA<br />

Efficacy:<br />

92%<br />

Dosage:<br />

Duration:<br />

Price:<br />

Storage:<br />

Safety:<br />

2 doses<br />

28 days apart<br />

$15 per dose<br />

−70 °C before delivery<br />

No major ADE reported<br />

during trials<br />

24 / FUTURE MEDICINE / <strong>December</strong> <strong>2020</strong>

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