Program of the 2001 International Worm Meeting - Sternberg Lab ...

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Parallel 1A: RNAi Royce Hall Auditorium, Saturday 9:00-11:00 am Mary Montgomery, Chair 16. Characterization of RNAi-sensitive mutators and the C. elegans Dicer homolog Sylvia E.J. Fischer, Rene F. Ketting, Pawel Pasierbek, Karen L. Thijssen, Ronald H.A. Plasterk 17. ego-1, a link between germline development and RNAi Eleanor M. Maine, Valarie E. Vought, Jamie Wasilenko. 18. Using RNAi to identify new components of the RNAi machinery Nathaniel R. Dudley, Jean-Claude Labbé, Bob Goldstein 19. Potential for Cross-Interference with RNAi Jeff Norman, Erin Bishop, Mary K. Montgomery 20. Mutants of C. elegans defective in uptake of dsRNA in RNAi Femke Simmer, Marcel Tijsterman, Kristy L. Okihara, Rene F, Ketting, Ronald H.A. Plasterk 21. RNAi analysis of 762 germline enriched genes. Fabio Piano, Aaron Schetter, Diane Morton, Kris Gunsalus, Valerie Reinke, Stuart Kim, Kenneth Kemphues 22. Roles for embryonic lethal genes on C. elegans Chromosome I identified by RNA interference and 4-dimensional video-microscopy and identification of a new Par-like gene Peder Zipperlen, Andrew G Fraser, Ravi S Kamath, Nathalie Le Bot, Monica Gotta, Maruxa Martinez-Campos, Julie Ahringer 23. Genome-wide functional analysis by RNAi-by-soaking with a non-redundant cDNA set Ikuma Maeda, Atsuko Minamida, Masayuki Yamamoto, Yuji Kohara, Asako Sugimoto 24. Identification of C. elegans genes required for the DNA damage response using a combination of functional genomic approaches Simon Boulton, Anton Gartner, Philippe Vaglio, Jérôme Reboul, David Hill, Marc Vidal Parallel 1B: Signal transduction Alex Hajnal, Chair 25. Two RGS proteins that inhibit Galphao and Galphaq signaling in C. elegans neurons require a Gbeta5-like subunit for function Daniel L. Chase, Georgia A. Patikoglou, Michael R. Koelle 26. eat-11 encodes GPB-2, a Gbeta5 ortholog that interacts with G o alpha and G q alpha to regulate C. elegans behavior Merrilee Robatzek * , Timothy Niacaris * , Kate Steger, Leon Avery, James H. Thomas 27. An N-terminal region of C. elegans RGS proteins EGL-10 and EAT-16 directs inhibition of Go alpha versus Gq alpha signaling Georgia A. Patikoglou, Michael R. Koelle 28. Novel downstream targets of GOA-1, EGL-30, GPA-12 and the C. elegans specific G-proteins Alexander M. van der Linden, Edwin Cuppen, Femke Simmer, Celine Moorman, Ronald H.A. Plasterk 29. THE G-PROTEIN COUPLED RECEPTOR SML-1 ANTAGONISES RAS/MAP KINASE SIGNALLING DURING OLFACTION AND VULVAL DEVELOPMENT Gopal Battu, Stefano Canevascini, Thomas Berset, Erika Fr„hli, Alex Hajnal 30. Modulation of inductive signaling during C. elegans vulval development Nadeem Moghal, Chieh Chang, L. Rene Garcia, Paul W. Sternberg 31. C. elegans POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and a noncanonical Wnt pathway that controls cell polarity Michael A. Herman, Kelly Greene
32. AN AXIN-LIKE PROTEIN FUNCTIONS AS A NEGATIVE REGULATOR OF WNT SIGNALING IN THE Q NEUROBLAST LINEAGE Hendrik C. Korswagen, Marco Betist, Damien Coudreuse, Hans C. Clevers 33. A genetic dissection of the minibrain kinase gene family and its role in Down syndrome William B. Raich, Celine Moorman, Clay O. Lacefield, Oliver Hobert, Ronald H.A. Plasterk, Eric R. Kandel 34. Two Isoforms of the EGL-15 (FGFR) Serve Different Functions Jay Goodman, Cathy Branda, Matthew Robinson, Michael Stern Parallel 1C: Embryonic Polarity and Divisions Pierre Gonczy, Chair 35. The Profilin PFN-1 is required for cytokinesis and cell polarity in the C. elegans embryo Aaron F. Severson, Bruce Bowerman 36. The Anaphase-Promoting Complex is required to polarize the one-cell C. elegans embryo. Chad Rappleye, Akiko Tagawa, Rebecca Lyczak, Bruce Bowerman, Raffi V. Aroian 37. spn-4 encodes a putative RNA binding protein required for mitotic spindle orientation and cell fate patterning in the C. elegans embryo José-Eduardo Gomes, Sandra E. Encalda, J. Clayton Carter, Kathryn A. Swan, Critopher A. Shelton, Bruce Bowerman 38. CDK-1 REGULATES SPINDLE ORIENTATION IN EARLY C. ELEGANS EMBRYOS Martha C. Soto, Yanxia Bei, Craig C. Mello 39. Phosphotyrosine signaling acts in parallel with Wnt signaling to specify endoderm and to control cleavage orientation in early C. elegans embryos Yanxia Bei, Jennifer Hogan, Martha Soto, Ka Ming Pang, John Collins, Craig C. Mello 40. Embryonic handedness choice in C. elegans involves a G alpha protein encoded by the spn-1 gene William B. Wood, Barbara Robertson, Dominique Bergmann 41. cdk-7 has independent roles in mRNA transcription and cell cycle progression in C. elegans embryos Matthew R. Wallenfang, Geraldine Seydoux 42. A novel protein required for degradation of CCCH finger proteins in somatic lineages. Kim Reese, Geraldine Seydoux 43. Wnt signaling and HAM-1 are required for asymmetric cell division of C. elegans neuroblasts. Nancy Hawkins, C. Andrew Frank, Gregory Ellis, Bruce Bowerman, Gian Garriga 44. A POP-1 repressor complex restricts inappropriate cell type-specific gene transcription during C. elegans embryogenesis Martin Victor, Dominica Calvo, Guangchao Sui, Margaret Po-Shan Luke, Gengyun Wen, Morris Maduro, Joel Rothman, Yang Shi Parallel 1E: Synaptic Function Ken Miller, Chair 45. Evidence that UNC-13 acts via syntaxin to promote vesicle priming Janet E. Richmond, Robby M. Weimer, Erik M. Jorgensen 46. Analysis of kin-13 PKC and dgk-1 DAG kinase suggests that phorbol esters regulate a late stage of synaptic vesicle exocytosis. Derek Sieburth, Jeremy Dittman, Stephen Nurrish, Joshua M. Kaplan 47. UNC-10 Rim, an active zone protein that regulates post-docking events at the synapse Sandhya P. Koushika, Janet E. Richmond, Richard Rolfe, Gayla Hadwiger, Erik M. Jorgensen, Michael L. Nonet 48. SLO-1 Potassium Channel Regulates Duration of Neurotransmitter Release Zhao-Wen Wang, Owais Saifee, Michael L. Nonet, Lawrence Salkoff
Page 1: Program of the 2001 International W
Page 5 and 6: 68. Assembly and function of the sy
Page 7 and 8: 106. Identifying muscle genes that
Page 9 and 10: 143. Roles of unc-34 and unc-40 in
Page 11 and 12: 177. Microevolution of vulval cell
Page 13 and 14: Gengyo-Ando, Yuji Kohara 214. Mutat
Page 15 and 16: 248. Signaling pathways in heat acc
Page 17 and 18: 283. UNC-16, A JNK signaling scaffo
Page 19 and 20: Immunity & infection Workshop Man-W
Page 21 and 22: 356. pvl-5 prevents Pn.p cell death
Page 23 and 24: 398. Isolation and analysis of chem
Page 25 and 26: 441. Characterization of FERM-domai
Page 27 and 28: 483. Reverse genetic analysis of a
Page 29 and 30: 527. A second function of the APC-r
Page 31 and 32: 567. A Screen for Mutations that En
Page 33 and 34: 609. Multiple defects in a C. elega
Page 35 and 36: 651. A Novel Ser/Thr Protein Kinase
Page 37 and 38: 693. Direct interaction between IP3
Page 39 and 40: Einhard Schierenberg 735. Computer
Page 41 and 42: 779. Evolution of homeotic gene fun
Page 43 and 44: 823. Calcium Regulatory Sites in UN
Page 45 and 46: 864. A screen for mutations affecti
Page 47 and 48: 907. Light-increased reversal frequ
Page 49 and 50: 949. Molecular and Genetic Characte
Page 51 and 52: 992. Forward and Reverse Genetic Ap
Page 53 and 54:
1034. Pristionchus pacificus mutant
Page 55 and 56:
1077. Expression of a C. elegans Mu
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1 1. MSP Signaling: Beyond the Sper
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3 3. IN VIVO DYNAMICS OF POP-1 ASYM
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4 PHA-4 is able to bind these sites
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6 identical to a mammalian nuclear
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8 spacing between the polyA site of
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11 11. 7,500 Genes and the Transiti
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13 13. Caenorhabditis Genetics Cent
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15 15. WormBase: A Web-accessible d
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17 17. ego-1, a link between germli
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19 19. Potential for Cross-Interfer
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22 basal transcription and further
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25 25. Two RGS proteins that inhibi
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28 28. Novel downstream targets of
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30 30. Modulation of inductive sign
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33 33. A genetic dissection of the
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35 35. The Profilin PFN-1 is requir
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37 37. spn-4 encodes a putative RNA
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39 39. Phosphotyrosine signaling ac
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41 lengthened interphase and M phas
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43 DSH-2 asymmetrically. In mom-5 m
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46 46. Analysis of kin-13 PKC and d
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48 48. SLO-1 Potassium Channel Regu
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51 51. unc-122 and unc-75: Two gene
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53 53. sol-1 encodes a novel protei
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55 cells. These findings suggest th
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57 addition, as with the FLP cells,
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60 60. Regulation of olfactory rece
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62 62. osm-5, the C. elegans homolo
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64 64. Multi-pathway Regulation of
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65 inactivation, in fact, affects p
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67 recombination. Altogether, this
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70 70. MES-4, a protein required fo
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72 72. Characterization of the C. e
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74 74. The intracellular domain of
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76 76. Regulation of fem-3 mRNA by
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78 78. Hermaphrodite or female? Spe
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80 80. Haldane’s Rule in Caenorha
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82 82. A cyclic GMP-dependent prote
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84 84. IDENTIFICATION OF AMP KINASE
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86 of mutant genomic DNA showed tha
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88 predauer. When this gene was kno
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90 However, when they are cultured
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92 sax-1 encodes a serine/threonine
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94 1 Dent et al. (1997) EMBO J. 16:
Page 145 and 146:
96 ttx-1 encodes a homeodomain prot
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98 proteins is unknown. Using GFP f
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100 (Miyahara et al. 1999 Internati
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103 103. In Vivo Optical Imaging of
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105 105. Creating transgenic lines
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107 107. M5 controls terminal bulb
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108 Similarly, PBO-4 contains a pot
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110 unknown signal or signals from
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112 acid repeats (1). These data su
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114 function to limit the rate of a
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116 other neuron tested, restores s
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119 119. UNC-58 IS AN UNUSUAL POTAS
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121 121. Analysis of the Sex-Specif
Page 171 and 172:
123 123. Dissection of DNA damage c
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125 125. CED-12, A COMPONENT OF A R
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127 127. A Novel Pharmacogenetic Mo
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129 predicted WW domain protein (ZK
Page 179 and 180:
132 132. zag-1, a Zn finger-homeodo
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134 134. A possible repulsive role
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136 136. Genetic Analysis of the Ka
Page 185 and 186:
138 138. Interacting proteins with
Page 187 and 188:
140 140. A genetic network involvin
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142 142. A Constitutively Active UN
Page 191 and 192:
144 144. Putative matrix proteins w
Page 193 and 194:
146 146. Maturation of the C. elega
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148 We have also initiated an analy
Page 197 and 198:
151 151. zyg-12 is required for the
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153 153. The mitosis-regulating kin
Page 201 and 202:
155 155. CDC-42, AGS-3 and heterotr
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157 157. The NED-8 ubiquitin-like c
Page 205 and 206:
159 159. OOC-5, required for polari
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161 3) Loss of dlg-1 activity leads
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163 epithelial tightness. Consisten
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165 ITR-1 regulates cytoskeletal re
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167 i) male tail defects; in genera
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170 170. mua genes function within
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172 lin-44(n1792); tlp-1(mh17) doub
Page 219 and 220:
174 required for the generation of
Page 221 and 222:
176 repressing the fusogenic activi
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178 lin-15A may therefore function
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181 181. Two enhancers of raf, eor-
Page 227 and 228:
183 In order to elucidate the mecha
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185 We have generated transgenic an
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187 expression reporter construct d
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189 for mRNA transcription, and may
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192 192. From Binding Sites to Targ
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194 194. The novel factor PEB-1 fun
Page 239 and 240:
196 196. Functional analysis of spl
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198 198. Operon Resolution, Usage a
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200 or CTP). Third, incorporation r
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202 late-stage populations that LIN
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204 Mutations in ocr-2 recapitulate
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206 specific promoters to drive the
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208 sensory signaling, we behaviora
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210 important for food-temperature
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213 213. Translational control of m
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215 215. MEX-3 Interacting Proteins
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217 217. The role of PLP-1 in mesen
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219 219. 4D-analysis of a collectio
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221 We also analyzed sperm developm
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224 224. lin-9, lin-35 and lin-36 n
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226 226. CUL-4 functions to prevent
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228 228. Genes that ensure genome s
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230 230. Open-reading-frame sequenc
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232 232. A snip-SNP map of the C. e
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234 WormPD, as well as the other vo
Page 277 and 278:
236 References: 1. Srinivasan. J et
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239 239. Rates and Patterns of Muta
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242 242. Global Analysis of Gene Ex
Page 283 and 284:
244 244. Signals from the reproduct
Page 285 and 286:
247 247. hif-1, a homolog of mammal
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250 250. The splicesomal Sm protein
Page 289 and 290:
252 252. GLHs associate with a LIM
Page 291 and 292:
254 254. Control of germline cell f
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256 region where GLD-1 levels fall
Page 295 and 296:
258 ClC-2 and CLH-3 share 40% amino
Page 297 and 298:
261 experiments showed that the two
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263 located within the ATPase domai
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265 We are using the collection of
Page 303 and 304:
267 in C. elegans. 268. Mutations i
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269 but they are often misplaced. F
Page 307 and 308:
271 M-lineage. By ablation it was s
Page 309 and 310:
273 aph-2 and Nicastrin are partial
Page 311 and 312:
275 hlh-2(RNAi) experiments suggest
Page 313 and 314:
278 278. Mesodermal cell fate speci
Page 315 and 316:
280 encoding a Rho GTPase. Overexpr
Page 317 and 318:
282 To test the lipid-binding model
Page 319 and 320:
284 carboxy-terminal EH domain. Yea
Page 321 and 322:
287 287. FUSOMORPHOGENESIS: A TALE
Page 323 and 324:
289 289. Chromosome-Wide Regulation
Page 325 and 326:
290 substrate(s) is currently under
Page 327 and 328:
292 more cycles of apparent replica
Page 329 and 330:
294 ags-3.2 and ags-3.3 encode esse
Page 331 and 332:
297 297. Mutations in the C elegans
Page 333 and 334:
299 299. THE ACTIN-BINDING PROTEIN
Page 335 and 336:
301 301. CED-12 functions in the CE
Page 337 and 338:
303 303. The C. elegans Autosomal D
Page 339 and 340:
305 To determine if cdf-1 affects t
Page 341 and 342:
307 part from a target dependent me
Page 343 and 344:
309 References: 1. Hekimi S, Boutis
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311 ligand may be a sterol derivati
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314 Mutations in two loci, daf-12 a
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316 which show a strong neuronal bi
Page 351 and 352:
318 318. Evolution of germ-line sig
Page 353 and 354:
320 320. Identifying universal Serr
Page 355 and 356:
322 wild-type cell lineage, which d
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324 quality of many commercial anti
Page 359 and 360:
326 While the nervous system appear
Page 361 and 362:
330 330. Molecular analysis of agin
Page 363 and 364:
333 333. Identification of two nove
Page 365 and 366:
335 and prolonged life span. Unlike
Page 367 and 368:
338 338. Caloric restriction activa
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340 full-length receptor. Its abund
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343 343. A bin’s-worth of bounty:
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345 345. Pheromone Regulation of da
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347 longest pure poly-Q run is 8 am
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350 daf-7(e1372)animals (63%, n=154
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352 In addition to their effect on
Page 381 and 382:
354 transcription or through a diff
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356 wild-type animals. Curiously, c
Page 385 and 386:
359 359. abl-1 Regulates C. elegans
Page 387 and 388:
362 362. What factors regulate prog
Page 389 and 390:
364 expression is confined to neuro
Page 391 and 392:
367 367. Characterization of a C el
Page 393 and 394:
370 370. MOLECULAR REGULATORS OF PO
Page 395 and 396:
372 using unc-51 promoter for panne
Page 397 and 398:
374 Taken together, these experimen
Page 399 and 400:
377 377. ACM-2, a neuronal muscarin
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379 strain. I intend to investigate
Page 403 and 404:
382 382. Isolation and analysis of
Page 405 and 406:
384 neurons but not in the muscles
Page 407 and 408:
386 neurons is 25 ± 4 μm. mec-7::
Page 409 and 410:
389 389. Engineering pharyngeal pum
Page 411 and 412:
391 391. ELECTROPHYSIOLOGICAL ANALY
Page 413 and 414:
394 394. Mechanisms involved in reg
Page 415 and 416:
396 396. Sniffing out the mechanism
Page 417 and 418:
398 398. Isolation and analysis of
Page 419 and 420:
401 401. Identification and Charact
Page 421 and 422:
403 403. The application of novel p
Page 423 and 424:
406 406. Activity-dependent transcr
Page 425 and 426:
408 expression of rcn-1 through GFP
Page 427 and 428:
411 411. Isolating redundant pathwa
Page 429 and 430:
413 413. syd-2 and rpm-1 function s
Page 431 and 432:
415 415. A screen to identify regul
Page 433 and 434:
417 bodies. Therefore, at least one
Page 435 and 436:
420 two predictions: (1) that if it
Page 437 and 438:
423 examined expression patterns of
Page 439 and 440:
425 gcy-5, gcy-6, and gcy-7. In eac
Page 441 and 442:
427 427. Isolation of mutants defec
Page 443 and 444:
429 429. Two-hybrid Screen for UNC-
Page 445 and 446:
431 phenotypes of both mutants are
Page 447 and 448:
433 specifically involved in retrog
Page 449 and 450:
435 fluorescence did not cause the
Page 451 and 452:
437 associate with endogenous worm
Page 453 and 454:
440 440. Microtubule based conventi
Page 455 and 456:
442 constructed double mutants of v
Page 457 and 458:
444 connections between the canal,
Page 459 and 460:
446 microtubules. (This work will a
Page 461 and 462:
449 449. or358ts is involved in mit
Page 463 and 464:
452 452. CeMCAK, a C. elegans kines
Page 465 and 466:
455 455. Characterization of rot-2,
Page 467 and 468:
457 followed by injection into wild
Page 469 and 470:
459 while astral microtubules are u
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463 463. Investigating the possibe
Page 473 and 474:
465 egl-35 mutations synthetically
Page 475 and 476:
467 associated with cyb (gk35). 468
Page 477 and 478:
469 cytokinesis. Cytokinesis can be
Page 479 and 480:
472 472. daz-1 , a C. elegans homol
Page 481 and 482:
474 474. him-8 and him-5 Philip M.
Page 483 and 484:
477 477. Identifying new genes that
Page 485 and 486:
479 against the lamprey vitellogeni
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481 nM calyculin A completely inhib
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483 F30A10.10 mutant showed vacuolo
Page 491 and 492:
486 486. spe-39 and Orthologs: A Ne
Page 493 and 494:
488 mediated degradation of specifi
Page 495 and 496:
491 491. Screening for sperm compet
Page 497 and 498:
494 494. A possible role for gcy-31
Page 499 and 500:
496 496. Genes Mediating Elongation
Page 501 and 502:
498 498. A Role for VAV-1 in Pharyn
Page 503 and 504:
500 We have narrowed the chromosoma
Page 505 and 506:
502 polarized secretion, activation
Page 507 and 508:
505 a low-penetrance "gob" phenotyp
Page 509 and 510:
508 508. Role of PDZ domain protein
Page 511 and 512:
511 511. Identification of discs la
Page 513 and 514:
514 alternatively spliced region of
Page 515 and 516:
517 517. Screening for Dorsal Inter
Page 517 and 518:
519 519. A Genetic Screen for New M
Page 519 and 520:
522 522. The C.elegans Mi-2 chromat
Page 521 and 522:
525 LIN-39 phosphorylation and dock
Page 523 and 524:
528 528. Suppression of mutation-in
Page 525 and 526:
530 approach should allow us to scr
Page 527 and 528:
533 533. MAB-18 BI-DIRECTIONALLY RE
Page 529 and 530:
535 535. Regulation of the ray posi
Page 531 and 532:
537 ankyrin and unc-34 are being te
Page 533 and 534:
540 540. Characterization of nuclea
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542 lis-1 in C. elegans. 543. C. el
Page 537 and 538:
546 546. Essential roles for C. ele
Page 539 and 540:
549 549. The cDNA sequence and expr
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551 551. A Caenorhabditis elegans c
Page 543 and 544:
554 554. Activation of protein degr
Page 545 and 546:
556 556. Identification and charact
Page 547 and 548:
558 558. Expression of C. elegans A
Page 549 and 550:
560 560. Functional analysis of pot
Page 551 and 552:
562 1. Kent, W.J. and Zahler, A.M.
Page 553 and 554:
565 565. Increased sensitivity to R
Page 555 and 556:
568 568. Pulling the Trigger of Tra
Page 557 and 558:
571 was about 100bp. We are current
Page 559 and 560:
574 574. Tissue expression, interac
Page 561 and 562:
576 expression at other sites. Stud
Page 563 and 564:
579 579. Nuclear Receptors Required
Page 565 and 566:
582 582. Using Genomics to Study Ho
Page 567 and 568:
584 584. Morphological Evolution of
Page 569 and 570:
586 Literature cited: Denver, D.R.,
Page 571 and 572:
590 590. There are at least four eE
Page 573 and 574:
592 dominance, independent assortme
Page 575 and 576:
594 The class meets once/week for 4
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597 597. Surfing the Genome: Using
Page 579 and 580:
600 presented at this meeting by Pr
Page 581 and 582:
603 603. Caenorhabditis elegans as
Page 583 and 584:
605 605. A bummed pathogen meets wi
Page 585 and 586:
607 607. Developing genetic methods
Page 587 and 588:
609 phenotype suggesting that the r
Page 589 and 590:
612 612. Insulin/IGF-like peptides
Page 591 and 592:
614 dauer morphogenesis, such as th
Page 593 and 594:
617 617. An Adaptive Response Exten
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620 620. Role of DAF-9 CYP450 in th
Page 597 and 598:
622 622. Nuclear Lamina Characteriz
Page 599 and 600:
Page 601 and 602:
627 627. Phagocytosis of necrotic c
Page 603 and 604:
629 and clearance in C.elegans. 1.F
Page 605 and 606:
631 mediated endocytosis (Grant and
Page 607 and 608:
634 634. BAG1, AN HSP70 CO-CHAPERON
Page 609 and 610:
637 637. HSP90 mRNA in the nematode
Page 611 and 612:
640 640. A study of the osmotic str
Page 613 and 614:
642 To develop a genetic method for
Page 615 and 616:
644 Mammalian FGFRs activate RAS si
Page 617 and 618:
647 647. Genetic analysis of the Ra
Page 619 and 620:
649 mechanism of regulation of RGS
Page 621 and 622:
651 cuticular structures ("treads")
Page 623 and 624:
654 654. Characterization of the sp
Page 625 and 626:
656 Serotonin-deficient mutants and
Page 627 and 628:
659 659. Imaging of neuroal activit
Page 629 and 630:
661 661. Making the Matrix: MEC-1,
Page 631 and 632:
663 663. Elaborating the compositio
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664 to at least the ~100 cell stage
Page 635 and 636:
666 The alpha-amino-3-hydroxy-5-met
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669 669. GENES SHOWING ALTERED EXPR
Page 639 and 640:
671 671. EVIDENCE FOR A CHA-1-SPECI
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673 these mutants further supportin
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675 1 Horvitz HR et al, Science 216
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679 679. Specificity of G-protein s
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681 681. A Genetic Interaction Betw
Page 649 and 650:
683 683. A Dopamine Receptor in C.
Page 651 and 652:
685 685. Characterizing the C. eleg
Page 653 and 654:
688 688. Alternative isoforms and m
Page 655 and 656:
690 contortus subunits. 691. Expres
Page 657 and 658:
694 694. The unc-63 gene encodes a
Page 659 and 660:
696 696. Identifying Modulators of
Page 661 and 662:
699 699. CARGO RECOGNITION BY SYNAP
Page 663 and 664:
701 701. Cloning and characterizati
Page 665 and 666:
703 703. zd8 causes cell migration
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705 homeodomain and thus deletes th
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707 target(s). We have seen no noti
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710 710. THE IDENTIFICATION OF PROT
Page 673 and 674:
711 offers a simple system to study
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713 autonomous. Since the MIG-17 me
Page 677 and 678:
716 716. ADM-1 AND ADM-2: DISINTEGR
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718 718. A SCREEN FOR REGULATORS OF
Page 681 and 682:
720 720. An in vitro System for Stu
Page 683 and 684:
723 723. Localization of innexins T
Page 685 and 686:
725 725. Characterization of C. ele
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727 no mutant phenotypes were obser
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729 the hyodermis and pharynx remai
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732 α-tubulin was normal. These ob
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735 735. Computer Simulation of Ear
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738 738. Toward an understanding of
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740 We were intrigued to find that
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742 alleles fail to complement evl-
Page 701 and 702:
744 each nucleus seemed equal and n
Page 703 and 704:
747 747. STU-4, the C. elegans homo
Page 705 and 706:
749 preparation and 2D-gel electrop
Page 707 and 708:
752 752. SNP Mapping of ego-3, a C.
Page 709 and 710:
755 755. Functional analysis of two
Page 711 and 712:
757 757. The C. elegans ptc and ptr
Page 713 and 714:
759 759. PGL-1, PGL-2, and PGL-3, a
Page 715 and 716:
761 761. The nuclear receptor SEX-1
Page 717 and 718:
764 764. TRA-1 is a Phosphoprotein
Page 719 and 720:
767 767. C. elegans SMC complexes:
Page 721 and 722:
770 770. Characterizing the C. eleg
Page 723 and 724:
772 in skn-1(zu67) homozygotes gcs-
Page 725 and 726:
774 ceh-23 and kal-1, requires ceh-
Page 727 and 728:
778 778. What is TLF doing during t
Page 729 and 730:
781 781. Characterization of tissue
Page 731 and 732:
783 somatic gonad development. The
Page 733 and 734:
786 786. Functional requirement for
Page 735 and 736:
789 789. IDENTIFICATION AND CHARACT
Page 737 and 738:
792 792. Characterization of a New
Page 739 and 740:
795 795. Analysis of lin-1 Mutants
Page 741 and 742:
798 798. spr GENES: SUPPRESSORS OF
Page 743 and 744:
801 801. Genetics and genomics of h
Page 745 and 746:
803 803. Control of ins-33 transcri
Page 747 and 748:
805 We are currently determining wh
Page 749 and 750:
807 We are studying the ability of
Page 751 and 752:
809 mutants isolated in our let-7 p
Page 753 and 754:
811 homologue in C. elegans, tim-1,
Page 755 and 756:
814 814. Characterization of the mu
Page 757 and 758:
816 816. sem-3 encodes a cis-prenyl
Page 759 and 760:
818 818. PARAMYOSIN-GFPs RESCUE MUT
Page 761 and 762:
821 821. Effect of the alpha 2 Ca 2
Page 763 and 764:
823 823. Calcium Regulatory Sites i
Page 765 and 766:
825 825. CAM-1/KIN-8 Receptor Tyros
Page 767 and 768:
828 828. Loss of a dynamin related
Page 769 and 770:
830 830. Nematodes with Mitochondri
Page 771 and 772:
833 833. The Effects of Electron Tr
Page 773 and 774:
835 835. Cryofixation of C. elegans
Page 775 and 776:
837 837. Electron Tomography at an
Page 777 and 778:
840 840. A High Resolution Digital
Page 779 and 780:
842 842. New! Improved! Fixation pr
Page 781 and 782:
845 845. Correlation between transc
Page 783 and 784:
847 chromatin-IP-microarray strateg
Page 785 and 786:
850 850. NEMATODE.NET, a Tool for N
Page 787 and 788:
854 854. Characterization of a Shor
Page 789 and 790:
858 858. A genetic screen to identi
Page 791 and 792:
860 progress to identify these neur
Page 793 and 794:
863 genomes, and a 25 0 C F 2 Daf-c
Page 795 and 796:
866 866. The role of egl-32 in egg
Page 797 and 798:
868 868. Defining new components of
Page 799 and 800:
871 871. sma-9 and TGFbeta Signalin
Page 801 and 802:
874 acy-2 was previously reported t
Page 803 and 804:
877 877. Identification of lin-44(s
Page 805 and 806:
879 alpha-synuclein deposits in the
Page 807 and 808:
881 constructs encoding the extrace
Page 809 and 810:
884 884. Exploring necrotic cell de
Page 811 and 812:
886 886. SNAP-25, a Rat General Ane
Page 813 and 814:
888 888. Gain-of-function mutations
Page 815 and 816:
891 891. mab-21 expression is regul
Page 817 and 818:
894 894. Reproductive and Acute Tox
Page 819 and 820:
896 effects of chronic fluoxetine i
Page 821 and 822:
898 and binds NADP. Two such domain
Page 823 and 824:
900 PA phosphatase (PAP). Thus, tho
Page 825 and 826:
903 903. Characterization of the th
Page 827 and 828:
905 hours (0.5 ~ 4 hr), which impli
Page 829 and 830:
908 908. Factors that affect the su
Page 831 and 832:
911 911. A conserved mechanism of s
Page 833 and 834:
914 914. A screen for dominant enha
Page 835 and 836:
916 916. Are input and output defec
Page 837 and 838:
918 918. Visualizing synapses in th
Page 839 and 840:
920 920. The Role of Rapsyn in C el
Page 841 and 842:
922 922. Genetic and Phenotypic Ana
Page 843 and 844:
924 924. Probing the Go-Gq Signalin
Page 845 and 846:
926 PQR). These neurons are all con
Page 847 and 848:
928 Localized expression of an UNC-
Page 849 and 850:
930 rac-2 are each necessary for di
Page 851 and 852:
933 933. Molecular characterization
Page 853 and 854:
935 Hrs/Hrs-2, whereas the open rea
Page 855 and 856:
938 938. The C. elegans homologue o
Page 857 and 858:
941 941. unc-20 MAPS TO A REGION TH
Page 859 and 860:
943 943. Mutations in let-767, a st
Page 861 and 862:
946 946. Role of sphingolipids in C
Page 863 and 864:
948 948. Characterisation of mammal
Page 865 and 866:
950 950. ISOLATION AND CHARACTERIZA
Page 867 and 868:
952 Xenopus oocytes. We have demons
Page 869 and 870:
954 described gene involved in the
Page 871 and 872:
957 in the translational repression
Page 873 and 874:
960 posterior daughter E and this s
Page 875 and 876:
962 not eliminated the extra hypode
Page 877 and 878:
964 out of species homologue. Lastl
Page 879 and 880:
967 967. Chromosome remodeling duri
Page 881 and 882:
970 970. The HMGA proteins of C. el
Page 883 and 884:
973 973. In vivo studies of the nuc
Page 885 and 886:
975 1. Hecht et al. (1987) J. Cell
Page 887 and 888:
977 cul-2 embryonic phenotypes. The
Page 889 and 890:
979 1.Uhlman, F., Wernic, D., Poupa
Page 891 and 892:
981 similar to the tim-1 (RNAi) phe
Page 893 and 894:
983 Here we report our progress on
Page 895 and 896:
985 this mutation mainly affects th
Page 897 and 898:
987 the identity and fate of the tw
Page 899 and 900:
989 nos-2 RNA is not translated eff
Page 901 and 902:
991 diplotene earlier than in wild
Page 903 and 904:
993 Three of the Pro mutants we ide
Page 905 and 906:
Page 907 and 908:
998 meiotic/pachytene region of tra
Page 909 and 910:
1001 therefore the RNAi screen of a
Page 911 and 912:
1004 1004. Is PAR-2 an E3 Ubiquitin
Page 913 and 914:
1007 P12 specification phenotype of
Page 915 and 916:
1010 1010. A screen for factors aff
Page 917 and 918:
1012 reference to sensory ray 6 dif
Page 919 and 920:
1015 1015. Defining Regulatory Regi
Page 921 and 922:
1017 1017. The Roles of cis-element
Page 923 and 924:
1019 1019. Computer prediction of c
Page 925 and 926:
1022 to binding sites for known C.
Page 927 and 928:
1024 (1) Berset et al. Science 291,
Page 929 and 930:
1027 1027. FUNCTIONAL STUDIES OF TH
Page 931 and 932:
1029 1029. Organogenesis of the C.
Page 933 and 934:
1031 these pseudovulvae are connect
Page 935 and 936:
1033 between induction and division
Page 937 and 938:
1036 mab-5 mutants. [1] Sommer R.J.
Page 939 and 940:
1039 1039. Cell fate specification
Page 941 and 942:
1042 regulated either directly or i
Page 943 and 944:
1045 1045. GENETIC INTERACTIONS BET
Page 945 and 946:
1047 1047. Prolyl 4-hydroxylase - e
Page 947 and 948:
1050 1050. Chemical and Genetic Inh
Page 949 and 950:
1053 lysate. Recently, it was sugge
Page 951 and 952:
1055 1055. Mutants with larger body
Page 953 and 954:
1057 To further understand which ge
Page 955 and 956:
1061 1061. ceh-13 shares overlappin
Page 957 and 958:
1063 1063. Novel and Atypical Recep
Page 959 and 960:
1065 1065. Comparative study of lin
Page 961 and 962:
1067 1067. Molecular Analysis of da
Page 963 and 964:
1069 immune system of the human hos
Page 965 and 966:
1073 1073. The regulation of gut de
Page 967 and 968:
1076 function of the nhr-85 gene. W
Page 969 and 970:
1078 propagation involves feedback
Page 971 and 972:
1080 by the lack of del-1::GFP expr
Page 973 and 974:
1082 Mapping and rescue experiments
Page 975 and 976:
1085 1085. A new method of analyzin
Page 977 and 978:
1088 1088. A SURVEY OF CHEMICALS AF
Page 979 and 980:
1090 618-codon open reading frame.
Page 981 and 982:
1093 1093. Toward a Genome-Wide RNA
Page 983 and 984:
1095 primers, formation of deletion
Page 985 and 986:
1098 1098. Thermokinesis: A New Ass
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