03.02.2022 Views

A Literature Review and Meta Analysis of the Effects of Lockdowns on COVID 19 Mortality

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Today, it remains an open questi<strong>on</strong> as to whe<str<strong>on</strong>g>the</str<strong>on</strong>g>r lockdowns have had a large, significant effect<br />

<strong>on</strong> <strong>COVID</strong>-<strong>19</strong> mortality. We address this questi<strong>on</strong> by evaluating <str<strong>on</strong>g>the</str<strong>on</strong>g> current academic literature<br />

<strong>on</strong> <str<strong>on</strong>g>the</str<strong>on</strong>g> relati<strong>on</strong>ship between lockdowns <str<strong>on</strong>g>and</str<strong>on</strong>g> <strong>COVID</strong>-<strong>19</strong> mortality rates. 3 We use “NPI” to<br />

describe any government m<str<strong>on</strong>g>and</str<strong>on</strong>g>ate which directly restrict peoples’ possibilities. Our definiti<strong>on</strong><br />

does not include governmental recommendati<strong>on</strong>s, governmental informati<strong>on</strong> campaigns, access<br />

to mass testing, voluntary social distancing, etc., but do include m<str<strong>on</strong>g>and</str<strong>on</strong>g>ated interventi<strong>on</strong>s such as<br />

closing schools or businesses, m<str<strong>on</strong>g>and</str<strong>on</strong>g>ated face masks etc. We define lockdown as any policy<br />

c<strong>on</strong>sisting <str<strong>on</strong>g>of</str<strong>on</strong>g> at least <strong>on</strong>e NPI as described above. 4<br />

Compared to o<str<strong>on</strong>g>the</str<strong>on</strong>g>r reviews such as Herby (2021) <str<strong>on</strong>g>and</str<strong>on</strong>g> Allen (2021), <str<strong>on</strong>g>the</str<strong>on</strong>g> main difference in this<br />

meta-analysis is that we carry out a systematic <str<strong>on</strong>g>and</str<strong>on</strong>g> comprehensive search strategy to identify all<br />

papers potentially relevant to answer <str<strong>on</strong>g>the</str<strong>on</strong>g> questi<strong>on</strong> we pose. We identify 34 eligible empirical<br />

studies that estimate <str<strong>on</strong>g>the</str<strong>on</strong>g> effect <str<strong>on</strong>g>of</str<strong>on</strong>g> m<str<strong>on</strong>g>and</str<strong>on</strong>g>atory lockdowns <strong>on</strong> <strong>COVID</strong>-<strong>19</strong> mortality using a<br />

counterfactual difference-in-difference approach. We present our results in such a way that <str<strong>on</strong>g>the</str<strong>on</strong>g>y<br />

can be systematically assessed, replicated, <str<strong>on</strong>g>and</str<strong>on</strong>g> used to derive overall meta-c<strong>on</strong>clusi<strong>on</strong>s. 5<br />

2 Identificati<strong>on</strong> process: Search strategy <str<strong>on</strong>g>and</str<strong>on</strong>g> eligibility criteria<br />

Figure 3 shows an overview <str<strong>on</strong>g>of</str<strong>on</strong>g> our identificati<strong>on</strong> process using a flow diagram designed<br />

according to PRISMA guidelines (Moher et al. (2009). Of 18,590 studies identified during our<br />

database searches, 1,048 remained after a title-based screening. Then, 931 studies were excluded,<br />

because <str<strong>on</strong>g>the</str<strong>on</strong>g>y ei<str<strong>on</strong>g>the</str<strong>on</strong>g>r did not measure <str<strong>on</strong>g>the</str<strong>on</strong>g> effect <str<strong>on</strong>g>of</str<strong>on</strong>g> lockdowns <strong>on</strong> mortality or did not use an<br />

empirical approach. This left 117 studies that were read <str<strong>on</strong>g>and</str<strong>on</strong>g> inspected. After a more thorough<br />

assessment, 83 <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> 117 were excluded, leaving 34 studies eligible for our meta-analysis. A<br />

table with all 83 studies excluded in <str<strong>on</strong>g>the</str<strong>on</strong>g> final step can be found in Appendix B, Table 8.<br />

3<br />

We use “mortality” <str<strong>on</strong>g>and</str<strong>on</strong>g> “mortality rates” interchangeably to mean <strong>COVID</strong>-<strong>19</strong> deaths per populati<strong>on</strong>.<br />

4<br />

For example, we will say that Country A introduced <str<strong>on</strong>g>the</str<strong>on</strong>g> n<strong>on</strong>-pharmaceutical interventi<strong>on</strong>s school closures <str<strong>on</strong>g>and</str<strong>on</strong>g><br />

shelter-in-place-orders as part <str<strong>on</strong>g>of</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g> country’s lockdown.<br />

5<br />

An interesting questi<strong>on</strong> is, “What damage lockdowns do to <str<strong>on</strong>g>the</str<strong>on</strong>g> ec<strong>on</strong>omy, pers<strong>on</strong>al freedom <str<strong>on</strong>g>and</str<strong>on</strong>g> rights, <str<strong>on</strong>g>and</str<strong>on</strong>g> public<br />

health in general?” Although this questi<strong>on</strong> is important, it requires a full cost-benefit study, which is bey<strong>on</strong>d <str<strong>on</strong>g>the</str<strong>on</strong>g><br />

scope <str<strong>on</strong>g>of</str<strong>on</strong>g> this study.<br />

5

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