Engineering Biology Problems Book (2021, Obninsk Edition)

resurrect an extinct species using preserved or newly synthesized genetic material.
SOLUTION:
This problem is currently being addressed by researchers from the University of Pennsylvania (USA),
Sooam Science Center (South Korea), and Northeastern Federal University (Russia). However, there
have been criticisms regarding the preservation of ancient DNA [16].
[14,15,16. Gupta MK, Das ZC, Heo YT, Joo JY, Chung H-J, Song H, et al. Transgenic chicken, mice,
cattle, and pig embryos by somatic cell nuclear transfer into pig oocytes. Cellular Reprogramming
2013;15:322–8. doi:10.1089/cell.2012.0074. Stone R. A Rescue Mission for Amphibians at the Brink
of Extinction. Science 2013;339:1371–1371. doi:10.1126/science.339.6126.1371. Grigorenko, A. P.,
Borinskaya, S. A., Yankovsky, N. K., & Rogaev, E. I. (2009). Achievements and features in working
with ancient DNA and DNA from complex forensic samples. Acta Naturae (Russian version), 1(3).]
1.32. Designing the Dragon. Tales of the peoples of the world contain descriptions of many amazing
animals that have never existed in nature. How can a person design and assemble a dragon?
SOLUTION:
Can a person design and assemble a dragon? Theoretically, yes. However, at today's level of science,
this would require a texture - a living object taken as the basis.
Figure 1.9. Dragon, 1896. Joannes Jonstonus (A Description of the Nature of Four-footed Beasts).
It is suggested to use the tools available today in the laboratory.
The chassis can be a small lizard from Madagascar. This is a good model organism to start
experimental work.
Figure 1.10. the girdle-tail.
However, introducing growth hormones alone will not produce the desired result. Introducing changes
into an organism means studying its genome and the principles of gene regulation. Therefore, first of
all, it would be necessary to sequence its genome and study the transcriptome at different stages of
embryogenesis. Thus, revealing the gene networks responsible for the growth and the mechanisms of
their regulation.