The Use of Disposable and Alternative Purification Technologies for ...
The Use of Disposable and Alternative Purification Technologies for ...
The Use of Disposable and Alternative Purification Technologies for ...
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Examples <strong>of</strong> Process <strong>Use</strong> <strong>of</strong> <strong>Disposable</strong><br />
Bioreactors<br />
� <strong>Use</strong> <strong>of</strong> disposable bioreactors <strong>for</strong> production at 100L+ scale:<br />
• Pierce, LN <strong>and</strong> Shabram PW, “Scalability <strong>of</strong> a <strong>Disposable</strong> Bioreactor from 25 L – 500 L<br />
Run in Perfusion Mode with a CHO-Based Cell Line: A Tech Review,” BioProcessing<br />
Journal, July/Aug 2004.<br />
• Zhang, S et al, “Large Scale Production <strong>of</strong> Clinical Grade Adenovirus Vectors – Introgen’s<br />
Experience,” presentation at WilBio Viral Vectors <strong>and</strong> Vaccines Conference (2004).<br />
� <strong>Use</strong> <strong>of</strong> disposable bioreactors <strong>for</strong> production at smaller scales:<br />
• Jenderek, S et al, “Development <strong>of</strong> a Production <strong>and</strong> <strong>Purification</strong> Method <strong>for</strong> Type 5<br />
Adenovirus,” BioProcessing Journal, May/June 2005.<br />
� <strong>Use</strong> <strong>of</strong> disposable bioreactors to replace conventional<br />
bioreactors in the inoculum train <strong>of</strong> large scale processes:<br />
• Knevelman, C et al, “Characterisation <strong>and</strong> Operation <strong>of</strong> a <strong>Disposable</strong> Bioreactor as a<br />
Replacement <strong>for</strong> Conventional Steam in Place Inoculum Bioreactors <strong>for</strong> Mammalian Cell<br />
Culture Processes,” ACS poster presentation (2002).
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