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Dysuria with a Negative Urine Culture or When is a UTI not a UTI?

Dysuria with a Negative Urine Culture or When is a UTI not a UTI?

Dysuria with a Negative Urine Culture or When is a UTI not a UTI?

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Familial ovarian cancer syndromes<br />

• Family h<strong>is</strong>t<strong>or</strong>y of ovarian cancer<br />

– One 1˚ <strong>or</strong> 2˚ relative increases lifetime r<strong>is</strong>k of<br />

ovarian CA from 1.6% to 5%<br />

• Lynch II<br />

– Cancers of colon, breast, endometrium, ovary<br />

– 3-14% lifetime r<strong>is</strong>k ovarian CA<br />

• Hereditary breast-ovarian cancer syndrome<br />

– BRCA1: 35-45% will develop ovarian CA<br />

– BRCA2: 15-25%

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