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OCTAX polarAIDE applications

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2<br />

TM TM<br />

<strong>OCTAX</strong> EyeWare Basic with <strong>OCTAX</strong> Eye USB2.0 camera<br />

All-purpose image processing and archiving for IVF<br />

TM<br />

<strong>OCTAX</strong> EyeWare Basic and our megapixel USB2.0<br />

camera are building the platform of the <strong>OCTAX</strong><br />

modular concept. Whether you need to do simple<br />

image capture, spindle analysis, IMSI or laser<br />

microsurgery - all <strong>OCTAX</strong> hard- and software tools can<br />

TM<br />

be combined into the EyeWare environment. Keep it<br />

easy by doing all in one software!<br />

TM<br />

EyeWare Basic features<br />

live video display with megapixel resolution<br />

unlimited Quickfile snapshot gallery<br />

database for patient data, images and videos<br />

biometric measurement tools<br />

various hardcopy report formats<br />

multilingual (English, French, Chinese, Japanese, German)<br />

control of all <strong>OCTAX</strong> hardware components<br />

(laser, motorized stage, heater, etc.)<br />

TM<br />

EyeWare Basic advantages<br />

easy to use<br />

unmatched image quality<br />

high resolution live video<br />

automatic brightness correction for undisturbed working<br />

one-button instantaneous snapshot to Quickfile<br />

video recording and network broadcasting features available<br />

TM<br />

full compatibility with <strong>OCTAX</strong> Laser Shot ,<br />

TM TM<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> and <strong>OCTAX</strong> cytoScreen :<br />

do all in one software!


TM<br />

Extensions to <strong>OCTAX</strong> EyeWare Basic<br />

TM<br />

<strong>OCTAX</strong> EyeWare MX<br />

TM<br />

unlimited digital video recording (also filed in <strong>OCTAX</strong> EyeWare database)<br />

TM<br />

multi-camera support by one <strong>OCTAX</strong> EyeWare MX license<br />

time lapse recording function<br />

advanced export functions (PowerPoint slides, time lapse video)<br />

network broadcasting function for live video<br />

TM<br />

<strong>OCTAX</strong> EyeWare Web<br />

remote access to patient data base and Quickfile<br />

download of images to a local PC<br />

watch streaming live video from remote PC<br />

optional password protection<br />

Documentation of cell development by <strong>OCTAX</strong> EyeWare<br />

Ref. 19311/9148<br />

TM<br />

<strong>OCTAX</strong> EyeWare Web Pro<br />

SQL server based database technology for optimum multi-user support (Intranet)<br />

TM<br />

remote access to the database even if <strong>OCTAX</strong> EyeWare is inactive<br />

Ref. 19311/9248<br />

Photos of assisted hatching and cell development, courtesy Dr. A. Senn, CHUV, Lausanne<br />

3


4<br />

TM<br />

<strong>polarAIDE</strong> : various imaging modes<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> TM<br />

Innovative spindle and zona pellucida analysis for IVF<br />

TM<br />

<strong>polarAIDE</strong> components<br />

green filter<br />

polarizer<br />

PC controlled analyzer<br />

TM<br />

<strong>OCTAX</strong> Eye USB 2.0 camera<br />

TM<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> software<br />

TM<br />

<strong>polarAIDE</strong> features<br />

spindle imaging: all relevant tools included<br />

automatic zona pellucida analysis<br />

quick and easy<br />

no calibration, no background subtraction<br />

TM<br />

all-purpose IVF imaging software included (<strong>OCTAX</strong> EyeWare Basic)<br />

TM<br />

full <strong>OCTAX</strong> Laser Shot / Fertilase compatibility: do all in one software!<br />

TM<br />

<strong>polarAIDE</strong> requirements<br />

inverted microscopes: Olympus, Nikon, Leica and Zeiss<br />

models are supported<br />

appropriate stage heating<br />

glass bottom dishes for analysis<br />

recent PC with 17” monitor<br />

TM<br />

<strong>polarAIDE</strong> stand-alone system Ref. 19330/0011<br />

TM<br />

<strong>polarAIDE</strong> upgrade system Ref. 19330/0012<br />

TM<br />

International patents pending. <strong>polarAIDE</strong> is currently not available in U.S.A.


TM<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> <strong>applications</strong><br />

Verify oocyte maturity to optimise your ICSI fertilization rate!<br />

Bright field view: mature (metaphase II) ?<br />

Automatically identify the most promising oocytes within seconds:<br />

by quantitative, user-independent zona pellucida analysis!<br />

High quality oocyte as scored by <strong>OCTAX</strong> <strong>polarAIDE</strong> TM<br />

Check the viability of frozen-thawed metaphase II oocytes!<br />

Post-thaw M II oocytes with (left) and without (right) spindle<br />

... and many more!<br />

TM<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> reveals: immature (telophase I)!<br />

Live birth rate (%) in three patient groups after zona analysis<br />

Montag et al., RBM Online 16(2):239-244, 2008<br />

TM<br />

Meiotic stages as observed by <strong>polarAIDE</strong> (from left to right): metaphase I, telophase I, prophase I, metaphase II<br />

70<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

p < 0.025<br />

low/low high/low high/high<br />

zona birefringence of 2 embryos selected for transfer<br />

5


6<br />

<strong>OCTAX</strong> cytoScreen TM<br />

Affordable IMSI trough digital image enhancement<br />

compatible with your existing Hoffman ICSI microscope<br />

computer enhanced high-magnification microscopy for morphology based sperm selection<br />

no oil immersion, no DIC - practicable for existing workflow<br />

cost effective integration into your existing <strong>OCTAX</strong> environment (camera, imaging software, laser)<br />

total magnification adjustable, up to 10,000 x<br />

use your existing <strong>OCTAX</strong> laser for convenient sperm immobilization<br />

TM<br />

cytoScreen components<br />

Condenser<br />

Objective<br />

Camera<br />

Software<br />

TM<br />

cytoScreen features and performance<br />

Oil immersion<br />

Image quality<br />

Total magnification<br />

Dishes required<br />

Compatibility<br />

Existing Hoffman´s or relief contrast<br />

cost saving solution, condenser supports<br />

all potential <strong>applications</strong><br />

60x<br />

Large field of view allows sperm immobilization<br />

without changing magnification<br />

1.3 or 3.0 Megapixel<br />

Online zoom and image enhancement<br />

TM<br />

<strong>OCTAX</strong> polarAide spindle and zona imaging system<br />

TM<br />

and <strong>OCTAX</strong> Laser Shot can be integrated into the same<br />

environment<br />

No !<br />

easy handling, no cleaning, works with or<br />

without heated glass plate<br />

Good<br />

limited by the physical characteristics of the<br />

60x objective<br />

> 10,000x, with intermediate magnification 1.6x<br />

for practical reasons, the optimum range of<br />

magnification is between 5,000x and 7,000x<br />

Glass bottom dishes<br />

Can be mounted to most current inverted microscope models<br />

used for IVF<br />

TM<br />

cytoScreen stand-alone system Ref. 19340/0011<br />

TM<br />

cytoScreen upgrade system Ref. 19340/0021


Motorized Microscope Stage<br />

integrates with existing X/Y-stage. Replaces any existing insert such as thermo plates<br />

complete heated glass surface for perfect temperature control<br />

move the stage in µm steps by a simple mouse click<br />

adjust speed and directions dynamically by mouse action while the stage is moving<br />

suitable for assisted hatching, ICSI, IMSI and spindle analysis<br />

Key features of the motorized stage:<br />

high resolution positioning,<br />

min. step width < 0.2 µm<br />

movement, temperature and velocity are software controlled via <strong>OCTAX</strong> EyeWare<br />

USB 2.0 connectivity, control by mouse, keyboard or <strong>OCTAX</strong> keypad controller<br />

Ref. 19320/0002<br />

100....230 V AC 50/60 Hz to 12 V DC power supply<br />

currently available for<br />

Olympus and Nikon microscopes<br />

Y<br />

X<br />

Combine fast manual and PC controlled µm movements.<br />

movement and settings keypad controller for motorized stage zona thinning using the motorized stage<br />

7


Accessories<br />

<strong>OCTAX</strong> universal heating frame with glass bottom<br />

Ref. 19320/1032<br />

Precise and reliable<br />

temperature control<br />

for inverted<br />

microscopes with<br />

dish holding frame.<br />

Customized solutions<br />

Controlled via<br />

Opalstrasse 32<br />

D - 84032 Altdorf / Germany<br />

Phone: +49 (0) 871 975 19-0<br />

Fax: +49 (0) 871 975 19-70<br />

mail@mtg-de.com / www.mtg-de.com<br />

TM,<br />

<strong>OCTAX</strong> EyeWare ,<br />

or independently.<br />

Requirements:<br />

- USB 2.0 port<br />

TM<br />

Twin dish holder: new tool for <strong>OCTAX</strong> cytoScreen<br />

Ref. 19340/0067<br />

For easy and<br />

controlled transfer<br />

of sperm from glass<br />

bottom dish to<br />

plastic ICSI dish.<br />

USB Photo printer<br />

Ref. 19310/5148 FP<br />

June 2008. All product and trade names are recognized as the property of their respective owners.<br />

(Specifications are subject to change without notice)<br />

Keypad controller, Laser hand- and foot switch<br />

Ref. 19310/5148KC, 19310/5148HS, 19310/1148<br />

Your local MTG agent or distributor is:<br />

(left)<br />

Additional control<br />

panel for motorized<br />

stage.<br />

(center and right)<br />

Additional trigger for<br />

<strong>OCTAX</strong> laser shot.<br />

Available as foot trigger<br />

an as hand trigger.<br />

Requirements:<br />

- USB port<br />

Magnification 25x,<br />

HMC compatible,<br />

extra long working<br />

distance (ELWD).<br />

Delivers sharp and high<br />

contrast images.<br />

Available for all major<br />

brands and types of<br />

inverted microscopes.<br />

The <strong>OCTAX</strong> Biopsy<br />

objective works<br />

perfectly with<br />

<strong>OCTAX</strong> <strong>polarAIDE</strong> .<br />

TM<br />

<strong>OCTAX</strong> EyeWare Multi - User Video transfer prior to ET Info terminal<br />

Connect more than one video source to<br />

TM<br />

<strong>OCTAX</strong> EyeWare . Each video source can use<br />

a separate monitor and keyboard for full control<br />

of image and video acquisition.<br />

Broadcast live<br />

video from<br />

stereo<br />

microscope to<br />

transfer room.<br />

Broadcast any live video from the <strong>OCTAX</strong><br />

computer to an information terminal or video<br />

display installed in any other room.<br />

one computer more than one camera and monitor<br />

Direct photo print<br />

from <strong>OCTAX</strong><br />

TM<br />

EyeWare live video.<br />

High resolution full<br />

color images in picture<br />

postcard size.<br />

Optionally, any logo can<br />

be printed on the photo.<br />

Requirements:<br />

- USB 2.0 port<br />

<strong>OCTAX</strong> Eye USB 2.0 3-Megapixel camera<br />

Ref. 19310/5150<br />

Resolution:<br />

up to 2048 x 1536 pixel<br />

<strong>OCTAX</strong> Biopsy objective<br />

Ref. 19310/4149<br />

Patients can<br />

watch the<br />

loading of the<br />

transfer catheter.<br />

Frame rate:<br />

up to 30 fps<br />

Color:<br />

true color<br />

Requirements:<br />

- USB 2.0 port<br />

- c-mount adaptor

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