European Committee on Antimicrobial Susceptibility Testing - eucast

Moraxella catarrhalis
Macrolides, lincosamides and streptogramins
Azithromycin 0.25 1
Clarithromycin 0.25 1
Erythromycin 0.25 0.5 15 23 20
Roxithromycin 0.5 1
Telithromycin 0.25 0.5 15 23 20
Clindamycin - - - -
Quinupristin-dalfopristin - - - -
Tetracyclines MIC breakpoint Disk Zone diameter
(mg/L) content
(µg)
breakpoint (mm)
S ≤ R > S ≥ R <
Doxycycline 1 1
Minocycline 1 1
2 1 30 25 A
22 A
Tetracycline 1 2 30 28 25
Tigecycline IE IE IE IE
Miscellaneous agents
0.5 1
0.5 1
1 1
2 1
Note A
Note A
Note A
Note A
EUCAST Clinical Breakpoint Table v. 2.0, valid from 2012-01-01
Note A 1/A. Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.
Note A
Note A
Note A 1/A. Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may
be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline
resistant isolates if required.
Chloramphenicol 2 1
2 1 30 30 A
30 A 1/A. Breakpoints relate to the topical use of chloramphenicol.
Colistin - - - -
Daptomycin - - - -
Fosfomycin iv IE IE IE IE
Fosfomycin-trometamol (uncomplicated UTI only) - - - -
Fusidic acid - - - -
Linezolid - - - -
Metronidazole - - - -
Mupirocin - - - -
Nitrofurantoin (uncomplicated UTI only) - - - -
Rifampicin - - - -
Spectinomycin - - - -
Trimethoprim (uncomplicated UTI only) - - - -
MIC breakpoint Disk Zone diameter Notes
(mg/L) content breakpoint (mm) Numbers for comments on MIC breakpoints
(µg)
Letters for comments on disk diffusion
S ≤ R > S ≥ R <
Notes
Numbers for comments on MIC breakpoints
Letters for comments on disk diffusion
MIC breakpoint Disk Zone diameter Notes
(mg/L) content breakpoint (mm) Numbers for comments on MIC breakpoints
(µg)
Letters for comments on disk diffusion
S ≤ R > S ≥ R <
Trimethoprim-sulfamethoxazole 1 0.5 1 1.25-23.75 18 15 1. Trimethoprim:sulfamethoxazole in the ratio 1:19. Breakpoints are expressed as the trimethoprim concentration.
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