PET/CT for radiotherapy planning of head-Ã¢ÂÂneck cancer

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RT planning process Item Item 1 • Item 2 • Item 3 Slide 28 / 86
RT planning process Radiotherapy requires a uniform dose distribution within the tumor. Target dose uniformity within +7% and -5% of the prescribed tumor dose. While sparing surrounding normal tissues To achieve this goal multiple beams are used Main steps in Treatment Planning 1. Define treatment volumes and risk organs 2. Define optimal beam setup 3. Calculate dose distribution within the patient and treatment times per beam 4. Plan evaluation Slide 29 / 86
Page 1 and 2: Dr. Wouter V. Vogel Department of N
Page 3 and 4: Topics ! Why PET/CT ? ! Diagnos3c v
Page 5 and 6: Anatomical imaging with CT Based on
Page 7 and 8: Molecular imaging ! Is a visual fun
Page 9 and 10: Reasons to perform PET/CT ! Does th
Page 11 and 12: Are there nodal metastases? DetecAo
Page 13 and 14: Are there distant metastases? For t
Page 15 and 16: MulAmodality more than nice colors
Page 17 and 18: MulAmodality: the greater perspecAv
Page 19: Planar image fusion 1953 Thyroid sc
Page 22 and 23: Radiotherapy what do we need?
Page 24 and 25: Increase therapeuAc raAo • Increa
Page 26 and 27: CTV Clinical Target Volume GTV with
Page 30 and 31: Sources of errors Inaccurate beam d
Page 32: PotenAal problems PET/CT imaging ca
Page 35 and 36: StandardizaAon of PET/CT imaging !
Page 37 and 38: AddiAonal paAent posiAoning Repeate
Page 39 and 40: Head/neck Required ! Flat table ! C
Page 41 and 42: Example: NO MASK Please don’t try
Page 43 and 44: Example: SubopAmal mask placement V
Page 45 and 46: Example: Success Results ! Image re
Page 47 and 48: DelineaAon: a mulAmodality procedur
Page 49 and 50: What does FDG PET not show ? Volume
Page 51 and 52: PET for GTV GTV involves all known
Page 53 and 54: Impact on volumes Method ! GTV 40 5
Page 55 and 56: A visual mulAmodality approach x !
Page 57 and 58: Interobserver variaAon - No PET 57
Page 59 and 60: StandardizaAon of delineaAon ! Deli
Page 61 and 62: PET for Boost definiAon A boost fie
Page 63 and 64: Day-‐to-‐day problems Facto
Page 65 and 66: Moving from tumor contouring to bio
Page 67 and 68: From where to what The Roman Dodeca
Page 69 and 70: FDG uptake predicts RT outcome [18F
Page 71 and 72: A different place for PET of nodes
Page 73 and 74: A different place for PET of nodes
Page 75 and 76: PotenAal impact ! Less opera3ons ne
Page 78 and 79:
PET for imaging of the delivered RT
Page 80 and 81:
External beam radiotherapy ! Looks
Page 82:
Uncertain proton range ! Proton dep
Page 85 and 86:
In-‐line PET images Image quali
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PET/CT for radiotherapy planning of head-Ã¢ÂÂneck cancer

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PET/CT for radiotherapy planning of head-Ã¢ÂÂneck cancer