Integrated Biomaterials Science

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Contents xv 4.6.2. 4.6.3. 4.6.4. 4.6.5. 4.6.6. 4.6.7. 4.6.8. 4.6.9. Poly(ester-amides) Polyorthoesters Polyanhydrides Poly(alkyl 2-cyanoacrylate) Polyimino Carbonates Polyphosphazenes Polyethyleneterephthalate Polyamides 4.6.10. Polyurethanes 4.7. Factors Affecting the Degradation of Polymeric Materials References 5. Bioceramics and Biological Glasses A. Krajewski and A. Ravaglioli 5.1. The Structure of Ceramics from Synthesis to Processing 5.1.1. 5.1.2. 5.1.3. 5.1.4. Ceramics The Outstanding Properties of Ceramics The Drawbacks of Ceramics The Structural Properties of Ceramics and Their Possibilities 5.1.5. Processing of Ceramics 5.1.6. The Thermal Process 5.1.7. Sintering 5.2. Design and Duration of Ceramic Devices under Load 5.3. Ceramics for Surgical Implants 5.3.1. Inert Bioceramics 5.3.2. Bioactive Ceramics 5.3.3. Ceramic and Polymeric Carbons 5.3.4. Biological Glasses 5.3.5. Coatings 5.4. A Survey on the Adhesion of Ceramics to Bone Tissue References 6. Metallic Materials Alberto Cigada, Roberto Chiesa, Maria Rosa Pinasco, and Kunihiro Hisatsune 6.1. 6.2. The Crystalline Structure of Metallic Materials Lattice Defects 6.2.1. Point Defects and Solid State Diffusion 6.2.2. Linear Defects and Plastic Deformation 6.2.3. Surface Defects and Grain Boundaries 6.2.4. Effect of Plastic Deformation Temperature on Grain Size 150 152 154 155 156 157 159 161 163 165 170 189 190 191 192 193 200 202 202 207 208 209 217 240 244 249 252 252 255 256 257 257 260 261
xvi Contents 6.3. Structure of Metallic Alloys 6.3.1. Interstitial Solid Solutions 6.3.2. Substitutional Solid Solutions 6.3.3. Intermetallic Phases 6.3.4. Presence of More Phases 6.4. Phase Diagrams 6.4.1. Phase 6.4.2. Variance and Phase Rule 6.4.3. Graphic Representation of Binary Phase Diagrams 6.4.4. Presence of One Phase 6.4.5. Presence of Two Phases and the Lever Rule 6.4.6. Presence of Three Phases 6.4.7. Iron–Carbon Phase Diagrams 6.4.8. Iron–Nickel and Iron-Chromium Diagrams 6.4.9. Titanium–Aluminum and Titanium–Vanadium Diagrams 6.5. 6.4.10. Other Phase Diagrams Thermal Treatments 6.5.1. Full Annealing 6.5.2. Normalization 6.5.3. Quenching 6.6. 6.5.4. Tempering Strengthening of Metals 6.6.1. Strengthening by Alloying 6.6.2. Strengthening by Work Hardening 6.6.3. Strengthening by Addition of Oligoelements 6.6.4. Strengthening by Thermal Treatments 6.6.5. Strengthening by Order–Disorder Transformations 6.7. Working Technologies 6.7.1. Hot or Cold Plastic Deformation 6.7.2. Molding 6.7.3. Powder Metallurgy 6.7.4. Tool Machining 6.7.5. Bonding 6.7.6. Surface Finishing 6.8. Main Metallic Materials Used as <strong>Biomaterials</strong> 6.8.1. Austenitic Stainless Steel 6.8.2. Cobalt Alloys 6.8.3. Titanium and Titanium Alloys 6.8.4. Precious Metal Alloys 7. Degradation Processes on Metallic Surfaces Emma Angelini, Angelo Caputo, and Fabrizio Zucchi 7.1. 7.2. Introduction The Biological Environment 262 262 262 263 263 263 263 264 264 265 266 267 268 269 269 271 272 276 277 277 277 277 278 278 278 279 279 280 281 285 287 288 288 289 289 290 291 292 294 297 297
Page 2 and 3: Integrated Biomaterials Science
Page 4 and 5: Integrated Biomaterials Science Edi
Page 6 and 7: To my wife, Gloria Rolando Barbucci
Page 8 and 9: Contributors Giovanni Abatangelo In
Page 10 and 11: Contributors ix Yoshito Ikada Resea
Page 12 and 13: Preface Progress in medical science
Page 14 and 15: Contents 1. Biological Materials Yo
Page 18 and 19: Contents xvii 7.3. Metallic Corrosi
Page 20 and 21: Contents xix 13.2.2. Annulus Fibros
Page 22 and 23: Contents xxi 17.5. 17.6. 17.7. 17.8
Page 24 and 25: Contents xxiii 22.8.4. Numerical Fo
Page 26 and 27: Contents xxv 27.3.3. 27.3.4. 27.3.5
Page 28 and 29: Contents xxvii 31.3. Artificial Ski
Page 30 and 31: Integrated Biomaterials Science
Page 32 and 33: Biological Materials Yoshito Ikada
Page 34 and 35: Biological Materials 3 keeping trip
Page 36 and 37: Biological Materials 5 Gelatin is a
Page 38 and 39: Biological Materials 7 1.2.2.2. Sta
Page 40 and 41: Biological Materials 9 Therefore, t
Page 42 and 43: Biological Materials 11 chitin and
Page 44 and 45: Biological Materials 13
Page 48 and 49: Biological Materials 17 ones. Four
Page 50 and 51: Biological Materials 19 1.3.3. Drug
Page 54 and 55: Biological Materials 23 Campoccia,
Page 56 and 57: Structure and Properties of Polymer
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Structure and Properties of Polymer
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Fundamentals of Polymeric Composite
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Biodegradable Polymers Luca Fambri,
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Biodegradable Polymers 121 literatu
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Biodegradable Polymers 123 reaction
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Biodegradable Polymers 125
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Biodegradable Polymers 129 for late
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Biodegradable Polymers 131 breaking
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Biodegradable Polymers 133 The usef
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Biodegradable Polymers 135 The most
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Biodegradable Polymers 137 establis
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Biodegradable Polymers 139 assemble
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Biodegradable Polymers 141 surgery.
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Biodegradable Polymers 143 Becker a
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Biodegradable Polymers 145 Polyhydr
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Biodegradable Polymers 147 excess o
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Biodegradable Polymers 149 approxim
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Biodegradable Polymers 151 properti
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Biodegradable Polymers 153 electron
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Biodegradable Polymers 155 exhibit
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Biodegradable Polymers 157 stabilit
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Biodegradable Polymers 159 degrade
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Biodegradable Polymers 161 arterial
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Biodegradable Polymers 163 4.6.10.
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Biodegradable Polymers 165 In fact,
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Biodegradable Polymers 169 higher t
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Biodegradable Polymers 171 Auger, F
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Biodegradable Polymers 173 Choi, N.
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Biodegradable Polymers 175 Friess,
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Biodegradable Polymers 177 Hudson,
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Biodegradable Polymers 179 Leenslag
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Biodegradable Polymers 181 Okada, T
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Biodegradable Polymers 183 Sandler,
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Biodegradable Polymers 185 Tormala,
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Biodegradable Polymers 187 Zhang, Y
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Bioceramics and Biological Glasses
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Metallic Materials Alberto Cigada,
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Metallic Materials 257 6.2.1. Point
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Metallic Materials 259 a. Work Hard
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Metallic Materials 261 At room (or
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Metallic Materials 263 Although the
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Metallic Materials 265 circle will
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Metallic Materials 267 In the same
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Metallic Materials 269 structure (c
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Metallic Materials 271 from (with a
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Metallic Materials 273
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Metallic Materials 275 results in c
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Metallic Materials 277 6.5.2. Norma
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Metallic Materials 279 6.6.4. Stren
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Metallic Materials 281 that one wis
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Metallic Materials 283
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Metallic Materials 285 In the case
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Metallic Materials 287 metals that
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Metallic Materials 289 6.7.6. Surfa
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Metallic Materials 291 (13-15%), mo
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Metallic Materials 293 by titanium
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Metallic Materials 295 known as fol
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Degradation Processes on Metallic S
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Degradation Processes in Metallic S
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Characterization of Biomaterials Do
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Characterization of Biomaterials 32
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Tissues Luigi Ambrosio, Paolo A. Ne
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Tissues 341 structure is adapted to
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Tissues 343 As a consequence of its
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Tissues 345 References Brooks, M. 1
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Soft Tissue Luigi Ambrosio, Paolo A
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Soft Tissue 349 10.1.2. Mechanical
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Soft Tissue 351 produce instantaneo
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Soft Tissue 353 nent is the free in
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Soft Tissue 355
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Soft Tissue 357 The loading produce
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Soft Tissue 359 stiffness in the fi
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Soft Tissue 361 and tendons may var
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Soft Tissue 363 response of the tis
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Soft Tissue 365 Montagna, W., Carli
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The Eye Domenico Lepore, Luigi Ambr
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The Eye 369
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The Eye 371 glycan complexes: GAG-a
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The Eye 373 11.3. The Sclera Togeth
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The Eye 375 and to explain, at leas
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The Eye 377 (diameter about 10 nm)
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The Eye 379 Moreover, the relations
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Articular Cartilage Paolo A. Netti
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Articular Cartilage 383 small perce
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Articular Cartilage 385 fibers (Sch
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Articular Cartilage 387 The exponen
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Articular Cartilage 389 ameters, th
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Articular Cartilage 391 where is th
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Articular Cartilage 393 al., 1986;
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Articular Cartilage 395
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Articular Cartilage 397 mechanical
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Articular Cartilage 399 Fung, Y.C.
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Articular Cartilage 401 Parkkinen,
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The Material and Mechanical Propert
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Properties of the Healthy and Degen
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Soft Tissue Replacement Matteo Sant
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Soft Tissue Replacement 427 valves
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Soft Tissue Replacement 429 minimiz
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Soft Tissue Replacement 431 14.2.1.
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Soft Tissue Replacement 433 materia
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Soft Tissue Replacement 435 complem
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Soft Tissue Replacement 437 tion by
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Soft Tissue Replacement 439 an asso
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Soft Tissue Replacement 441 by low
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Soft Tissue Replacement 443 may pre
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Soft Tissue Replacement 445 14.4.2.
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Soft Tissue Replacement 447 frictio
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Soft Tissue Replacement 449 14.5. C
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Soft Tissue Replacement 451 Anderso
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Soft Tissue Replacement 453 F.J., D
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Soft Tissue Replacement 455 Larsson
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Soft Tissue Replacement 457 Salib R
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Mechanics of Hard Tissues Arturo N.
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Mechanics of Hard Tissues 461 of bo
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Mechanics of Hard Tissues 463 repor
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Mechanics of Hard Tissues 465 water
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Mechanics of Hard Tissues 467 15.2.
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Mechanics of Hard Tissues 469 15.3.
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Mechanics of Hard Tissues 471 damag
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Mechanics of Hard Tissues 473 some
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Mechanics of Hard Tissues 475 emati
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Mechanics of Hard Tissues 477 of bo
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Mechanics of Hard Tissues 479 a. Fr
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Mechanics of Hard Tissues 481 Then
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Mechanics of Hard Tissues 483 the f
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Mechanics of Hard Tissues 485 et al
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Mechanics of Hard Tissues 487 Cowin
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Mechanics of Hard Tissues 489 Natal
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Hip Joint Prosthesis Giuseppe Guida
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Hip Joint Prosthesis 493 point of v
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Hip Joint Prosthesis 495 resulting
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Hip Joint Prosthesis 497 cavity in
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Hip Joint Prosthesis 499 extremity
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Hip Joint Prosthesis 501 The second
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Hip Joint Prosthesis 503 distributi
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Hip Joint Prosthesis 505 with metal
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Hip Joint Prosthesis 507 The femora
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Hip Joint Prosthesis 509 f. Materia
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Hip Joint Prosthesis 511 al., 1976;
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Hip Joint Prosthesis 513 The princi
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Hip Joint Prosthesis 515 polyethyle
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Hip Joint Prosthesis 517 1. Good pr
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Hip Joint Prosthesis 519 Certainly
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Hip Joint Prosthesis 521 Ambrosio,
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Hip Joint Prosthesis 523 Huiskes, R
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Hip Joint Prosthesis 525 Schmalzrie
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Knee Joint Replacements Dante Ronca
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Knee Joint Replacements 529 17.2. H
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Knee Joint Replacements 531 anatomi
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Knee Joint Replacements 533 arc and
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Knee Joint Replacements 535 In 1972
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Knee Joint Replacements 537 to the
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Knee Joint Replacements 539 et al.,
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Knee Joint Replacements 541 conform
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Knee Joint Replacements 543 strated
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Knee Joint Replacements 545 overall
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Knee Joint Replacements 547 are cen
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Knee Joint Replacements 549 condyle
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Knee Joint Replacements 551 Andriac
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Knee Joint Replacements 553 Ranawat
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Biomaterial Applications: Elbow Pro
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Biomaterial Applications: Shoulder
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Acrylic Bone Cements Maria-Pau Gine
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Acrylic Bone Cements 571 20.2.2. Ch
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Acrylic Bone Cements 573 the BP int
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Acrylic Bone Cements 575 behavior d
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Acrylic Bone Cements 577 Taking fat
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Acrylic Bone Cements 579 thickness
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581
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Acrylic Bone Cements 583 20.5. Some
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Acrylic Bone Cements 585 Charnley,
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Acrylic Bone Cements 587 Nguyen, N.
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Mechanical Properties of Tooth Stru
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Dental Materials and Implants 22 Ma
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Dental Materials and Implants 603 E
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Dental Materials and Implants 605 t
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Dental Materials and Implants 607 H
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Dental Materials and Implants 609 o
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Dental Materials and Implants 611 l
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Dental Materials and Implants 613 e
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Dental Materials and Implants 615 S
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Dental Materials and Implants 619 4
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Dental Materials and Implants 621 d
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Dental Materials and Implants 623 M
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Dental Materials and Implants 627 n
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Dental Materials and Implants 629 o
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Dental Materials and Implants 635 i
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Dental Materials and Implants 637 s
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Dental Materials and Implants 639 d
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Dental Materials and Implants 641 p
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Dental Materials and Implants 643 c
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Dental Materials and Implants 645
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Dental Materials and Implants 647 A
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Dental Materials and Implants 649 B
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Dental Materials and Implants 651 a
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Dental Materials and Implants 653 P
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Materials/Biological Environment In
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Protein Adsorption and Cellular/Tis
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Inflammatory Response to Polymeric
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Inflammatory Response to Metals and
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27 Biocompatibility and Biological
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Biocompatibility and Biological Tes
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Infection and Sterilization Roberto
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Infection and Sterilization 817 dev
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Infection and Sterilization 819 sum
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Infection and Sterilization 821 ste
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Infection and Sterilization 823
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Infection and Sterilization 825 fea
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Infection and Sterilization 827 The
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Infection and Sterilization 829 eff
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Infection and Sterilization 831 Gia
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Drug Delivery Systems Francesco M.
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Drug Delivery Systems 835 Controlle
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Drug Delivery Systems 837 exploitat
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Drug Delivery Systems 839 Further p
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Drug Delivery Systems 841 biomateri
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Drug Delivery Systems 843 Polymeriz
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Drug Delivery Systems 847 absorptio
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Drug Delivery Systems 849 Jaluronic
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Drug Delivery Systems 851 29.5.2. M
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Drug Delivery Systems 853 cal prope
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Drug Delivery Systems 855 It was fo
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Drug Delivery Systems 857 surface e
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Drug Delivery Systems 859 tris(3-is
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Drug Delivery Systems 861 The maint
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Drug Delivery Systems 863 chemical
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Drug Delivery Systems 865 rate-dete
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Drug Delivery Systems 867 Equation
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Drug Delivery Systems 869 Assuming
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Drug Delivery Systems 871 lines, an
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Drug Delivery Systems 873 Gurny, R.
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Gene Delivery as a New Therapeutic
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Tissue Engineering Giovanni Abatang
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Tissue Engineering 887 fundamental
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Tissue Engineering 889 unknown unti
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Tissue Engineering 891 Adhesive Gly
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Tissue Engineering 893 toward ident
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Tissue Engineering 895 31.2.4. Test
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Tissue Engineering 897 and Mikos, 1
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Tissue Engineering 899 systemic cir
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Tissue Engineering 901 Considering
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Tissue Engineering 903 their extrac
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Tissue Engineering 905
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Tissue Engineering 907 31.3.3. Conc
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Tissue Engineering 909 Cartilage is
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Tissue Engineering 911 arthroscopic
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Tissue Engineering 913 known to hav
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Tissue Engineering 915 powerful too
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Tissue Engineering 917 1996; Mankin
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Tissue Engineering 919 autografting
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Tissue Engineering 921 natural repa
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Tissue Engineering 923 31.5.4. Tiss
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Tissue Engineering 925 Finally, dif
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Tissue Engineering 927 31.6.4. Pare
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Tissue Engineering 929 devices have
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Tissue Engineering 931 after 2 year
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Tissue Engineering 933 contacts of
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Tissue Engineering 935 coculture of
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Tissue Engineering 937 Adams, J.C.,
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Tissue Engineering 939 Clement, B.,
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Tissue Engineering 941 Guillouzo, A
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Tissue Engineering 943 Martin, P. 1
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Tissue Engineering 945 Schwarz, R.P
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Assist Devices Gerardo Catapano 32.
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Assist Devices 949 All body fluids
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Assist Devices 951 fluid (e.g., a b
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Assist Devices 953 The quantity is
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Assist Devices 955 In blood process
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Assist Devices 957 but also electro
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Assist Devices 959 disorder and pat
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Assist Devices 961 the form of cann
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Assist Devices 963 preparation: The
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Assist Devices 965 complex. Extrusi
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Assist Devices 967 b. Synthetic Pol
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Assist Devices 969 was done before,
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Assist Devices 971 inflicted upon b
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Assist Devices 973 The most relevan
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Assist Devices 975 reduction is tra
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Assist Devices 977 supporting nearl
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Assist Devices 979
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Assist Devices 981 Thus, in additio
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Assist Devices 983 PS, polyvinyl co
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Standards on Biomaterials Maria Vit
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Standards on Biomaterials 987 the E
Page 1020 and 1021:
Standards on Biomaterials 989 the E
Page 1022 and 1023:
Standards on Biomaterials 991 Moreo
Page 1024 and 1025:
Standards on Biomaterials 993 make
Page 1026 and 1027:
Standards on Biomaterials 995 Plant
Page 1028 and 1029:
Standards on Biomaterials 997 Invas
Page 1030 and 1031:
Standards on Biomaterials 999 which
Page 1032 and 1033:
Standards on Biomaterials 1001 Part
Page 1034 and 1035:
Biomaterials and Patents Maria Vitt
Page 1036 and 1037:
Biomaterials and Patents 1005 Howev
Page 1038 and 1039:
Biomaterials and Patents 1007 “Th
Page 1040 and 1041:
Biomaterials and Patents 1009 34.1.
Page 1042 and 1043:
Biomaterials and Patents 1011 Howev
Page 1044 and 1045:
Biomaterials and Patents 1013 Nonet
Page 1046 and 1047:
Index A Acellular approaches, artif
Page 1048 and 1049:
Index 1017 Bacterial degradation, b
Page 1050 and 1051:
Index 1019 Bioresorbable polymers,
Page 1052 and 1053:
Index 1021 D Deacetylation, chitin
Page 1054 and 1055:
Index 1023 Eye, 367-379 cornea, 368
Page 1056 and 1057:
Index 1025 inorganic materials, 12
Page 1058 and 1059:
Index 1027 L Lactic/glycolic acid p
Page 1060 and 1061:
Index 1029 Microdebonding test, fib
Page 1062 and 1063:
Index 1031 carbon (graphite) fibers
Page 1064 and 1065:
Index 1033 Reverse transcription po
Page 1066 and 1067:
Index 1035 tissue engineering, 896-
Page 1068:
Index 1037 Unidirectional lamina el
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Integrated Biomaterials Science

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