Bifeng Pan

Introduction
Nanotechnology has tremendous potential in creating nanoparticle systems for
targeted drug delivery.
Nanoscale drug delivery system can deliver drugs to specific tissues in the body, and
enhance drug penetration into cells, and improve drug activity.
Cellular surface machinery and intracellular organelles operate at the nanolevel:
regulate the actions of messenger molecules, maintain ionic stability, and
manufacture a wide variety of crucial building blocks. Biochemical molecules ‘dock’
into larger nanoscale structures (10-100 nm) to mediate specific functions, or are
processed further through the active sites of receptors and enzymes.
Nanoparticles are ideal for interacting on the nanoscale and enabling effective and
selective therapeutics.
We will focus on nanoparticle systems for Si RNA delivery with the goal of
achieving ‘multi-targeted’ therapeutics.