Polymer Brushes for Molecular Transport - Paul Braun Research ...

More documents

Recommendations

Info

LIST OF ABBREIVIATIONS FRAP fluorescence recovery after photobleaching SAM self-assembled monolayer Tg glass transition temperature PEG poly(ethylene glycol) CTS chlorotrimethylsilane OTS octadecyltrichlorosilane CSLM confocal scanning laser microscope EOM electro-optical modulator ROI region of interest PMT photomultiplier tube SIP surface initiated polymerization PNIPAAm poly(N-isopropylacrylamide) LCST lower critical solution temperature ATRP atom transfer radical polymerization APS (aminopropyl)triethoxysilane PDMS poly(dimethylsiloxane) RIE reactive ion etching POEGA poly(oligoethylene glycol acrylate) DLS dynamic light scattering xii
CHAPTER 1 INTRODUCTION 1.1 Objectives and General Experimental Approaches 1.1.1 Objectives The primary goal of this thesis is to construct quasi two-dimensional “smart” molecular structures, using end-grafted polymer brushes as building blocks, which confine and regulate the transport of organic molecules, inorganic ions and nanoparticles (Figure 1.1). These well- defined, surface-bound polymer films act as a unique bridge that links the underlining surface, which can often be a solid inorganic or organic substrate, with the external environment, which can be a wide range of matters including vapors, fluids, solids and any combination of them, and more interestingly and more importantly, biomacromolecules such as proteins and DNA, and complex living organisms. It is scientifically and technologically intriguing to probe the molecular transport process mediated by the polymer brush pathways. By tuning different parameters in a model system consisting of diffusing species and the bound polymer entity, we can have a better knowledge about the thermodynamics and kinetics involved in the molecular transport in polymer brushes. Patterned polymer brush pathways represent a new paradigm for molecular transport, and it is envisioned that by patterning the brushes one will be able to have surface-directed molecular or ionic transport, separation, and chemical and biomolecular sensing properties that are important for a number of applications. A long term objective of this research is to build a full range of transporting media, for a wide variety of species, and gain advanced control on the architecture of the transport pathways. Surface treatments using polymer brushes have been demonstrated to be very efficient in 1
Page 1 and 2: POLYMER BRUSHES FOR MOLECULAR TRANS
Page 3 and 4: © 2005 by Huilin Tu. All rights re
Page 5 and 6: ABSTRACT This thesis studies 2-dime
Page 7 and 8: For my family v
Page 9 and 10: from a vision to concrete plans, an
Page 11 and 12: TABLE OF CONTENTS LIST OF ABBREVIAT
Page 13: 4.3.6.2 FRAP of Prodan in the patte
Page 17 and 18: fundamentally different from most o
Page 19 and 20: 1.1.2 General experimental approach
Page 21 and 22: 1.2.1 “Grafting to” approach
Page 23 and 24: mechanism at the later stage, and t
Page 25 and 26: laboratory), sometimes rough,[36] a
Page 27 and 28: (a) (b) Figure 1.4. Schematic repre
Page 29 and 30: 31. S.-J. Ahn, W.-K. Lee, S. Zausch
Page 31 and 32: CHAPTER 2 PRODAN DIFFUSION ON SELF-
Page 33 and 34: tested under continuous flow of nit
Page 35 and 36: coverslips. Water contact angle dat
Page 37 and 38: (a) 0 s 10 s 30 s 120 µm 60 s 120
Page 39 and 40: also sometimes observe bright dots
Page 41 and 42: and the dye, and thus recovery due
Page 43 and 44: 2.5 References 1. C. E. Heitzman, P
Page 45 and 46: formed on gold through microcontact
Page 47 and 48: organic solvents.) for 30 minutes f
Page 49 and 50: Scheme 3.1. SiO2 OH SiO2 O Si 3.2.4
Page 51 and 52: sp 3 hybridized carbon peak confirm
Page 53 and 54: Reflectivity Figure 3.5. X-ray refl
Page 55 and 56: The AFM images of the patterned PNI
Page 57 and 58: 3.3.7 Fluorescence studies 3.3.7.1
Page 59 and 60: FRAP images and corresponding fluor
Page 61 and 62: advancing water contact angles for
Page 63 and 64: ushes was in the range of 446-450 n
Page 65 and 66:
of interest to inside, and so the e
Page 67 and 68:
observed are rotational diffusion a
Page 69 and 70:
38. D. Hall, J. Torkelson, Macromol
Page 71 and 72:
energy-density battery applications
Page 73 and 74:
4.1.3 Oligoethylene glycol containi
Page 75 and 76:
was used to test the thickness chan
Page 77 and 78:
The samples are sonicated in aceton
Page 79 and 80:
ToF SIMS characterization of POEGA
Page 81 and 82:
0 = f where fp and fH2O are volume
Page 83 and 84:
T gp temperature over solvent glass
Page 85 and 86:
elative humidity), 25% relative hum
Page 87 and 88:
(a) 15s 30s 60s 120s Figure 4.8. FR
Page 89 and 90:
of 2.5 nm (as measured by AFM on a
Page 91 and 92:
4.3.5.2 Diffusion of Prodan in the
Page 93 and 94:
(a) (b) (c) (d) 500 nm 0 25 nm 0 0
Page 95 and 96:
Another possibility is that the nak
Page 97 and 98:
ToF SIMS, and the physical properti
Page 99 and 100:
26. L. Lavielle, in Polymer Surface
Page 101 and 102:
presence of a flat wall, and (4) mo
Page 103 and 104:
ultrasonication. After two centrifu
Page 105 and 106:
silicone solution holder (GRACE Bio
Page 107 and 108:
5.3.3 Temperature-response of the c
Page 109 and 110:
more frequently within its “cage
Page 111 and 112:
From the trajectories presented in
Page 113 and 114:
described by Equation 5.5. And then
Page 115 and 116:
3. D. Rosenbaum, P. C. Zamora, C. F
Page 117 and 118:
XPS and FTIR confirmed the chemical
Page 119 and 120:
developed in this thesis have intri
show all

Polymer Brushes for Molecular Transport - Paul Braun Research ...

Create successful ePaper yourself

Delete template?

Save as template?