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Department of - Instituut voor Tropische Geneeskunde

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Projects<br />

For more details, see www.itg.be/projects and fill in the<br />

project reference number<br />

Unit <strong>of</strong> Virology<br />

Reference number 84210/84211<br />

EMPRO European Microbicide Project<br />

ITM Promoter: G. Vanham<br />

ITM Collaborator: A. Buvé<br />

EMPRO-coordinater: C. Kelly (King’s College London)<br />

Support: European Commission<br />

Reference number 85101<br />

MMP Development <strong>of</strong> an association <strong>of</strong> one or more<br />

vaginal microbicidal formulations at the pre-clinical<br />

stage.<br />

ITM Promoter: G. Vanham<br />

MMP-coordinater: L. Belec (INSERM, France)<br />

External promoters: G. Van den Mooter, J. Balzarini & D.<br />

Schol (KUL, Belgium), S. di Fabio (ISS, Italy)<br />

Support: ANRS French National Agency for Research on<br />

Aids/Agence nationale de recherches sur le sida<br />

Reference number 100107<br />

Research collaboration on microbicides<br />

ITM promoter: G. Vanham<br />

External promoters: J. Van Roey (Tibotec, Belgium), IPM<br />

(International Partnership <strong>of</strong> Microbiocides Inc.)<br />

Support: Tibotec Pharmaceuticals Ltd, Ireland.<br />

Reference number 424402<br />

Sexual Transmission <strong>of</strong> HIV: viral selection, fitness<br />

and adaptation<br />

ITM promoter: G. Vanham<br />

ITM collaborator: J. Michiels<br />

External promoters: M. Temmerman & M. Praet<br />

(University <strong>of</strong> Ghent)<br />

Support: Research Foundation Flanders (FWO)<br />

Reference number 414401<br />

Inhibition <strong>of</strong> human immunodeficiency virus (HIV)<br />

replication<br />

ITM promoter: G. Vanham<br />

ITM collaborators: E. Van Gulck, D. Atkinson<br />

External promoters: Z. Bernemann (Antwerp University,<br />

Belgium, coordinator), B. Verhasselt (Ghent University,<br />

Belgium), M. Moutschen (University <strong>of</strong> Liège, Belgium),<br />

A-M Vandamme (Catholic University Leuven, Belgium), B.<br />

Berkhout (University <strong>of</strong> Amsterdam, The Netherlands).<br />

Support: Belgian Federal Science Policy Office (BELSPO)<br />

Reference number 100094<br />

Induction <strong>of</strong> immunity by dendritic cells in cancer and<br />

aids<br />

ITM-promoter: G. Vanham<br />

ITM-collaborators: K. Vereecken, S. Coppens, Y. Gali<br />

External promoters: Z. Berneman, E. Van Gulck and G. Van<br />

den Bosch (University <strong>of</strong> Antwerp, Belgium)<br />

Support: University <strong>of</strong> Antwerp (GOA)<br />

Reference number 100183<br />

Enhancement <strong>of</strong> antiviral immunity in seropositive<br />

individuals through vaccination with autologous<br />

dendritic cells expressing viral RNA obtained from<br />

endogenous quasispecies: preclinical evaluation in<br />

macaques<br />

ITM-promoter: G. Vanham<br />

Support: French National Agency for Research on Aids<br />

(AWRS)<br />

Reference number 424403<br />

A phase I/II study <strong>of</strong> therapeutic vaccination with<br />

autologous dendritic cells <strong>of</strong> HIV infected individuals<br />

under stable HAART<br />

ITM-promoter: G. Vanham<br />

External promoters: K. Thielemans (Free University <strong>of</strong><br />

Brussels, Belgium), Z. Berneman (Antwerp University<br />

Hospital, Belgium)<br />

Support: Institute for the Promotion <strong>of</strong> Innovation by<br />

Science and Technology in Flanders (IWT)<br />

Reference number 100217<br />

Vaccine induced protective cross-neutralisation <strong>of</strong><br />

HIV-1<br />

ITM promoters: G. Vanham, W. Janssens<br />

ITM collaborators: S. Balla-Jhagjhoorsingh, B. Willems, L.<br />

Heyndrickx, K. Vereecken, N. Loots<br />

External promoters: R.A. Weiss (University College<br />

London, United Kingdom), A. McKnight(Queen Mary<br />

University <strong>of</strong> London, United Kingdom), J. Heeney and<br />

D. Davis (Biomedical Primate Research Centre, The<br />

Netherlands), A. Lanzavecchia (Institute for Research<br />

in Biomedicine, Switzerland), Q. Sattentau (University<br />

RESEARCH | 41

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