Measles IgG serology - UK NEQAS for MICROBIOLOGY
Measles IgG serology - UK NEQAS for MICROBIOLOGY
Measles IgG serology - UK NEQAS for MICROBIOLOGY
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<strong>UK</strong> National External Quality Assessment Service <strong>for</strong> Microbiology<br />
Distribution : 2836<br />
Dispatch Date : 09-May-2011<br />
<strong>for</strong> <strong>Measles</strong> <strong>IgG</strong> <strong>serology</strong><br />
Intended Result Your Report<br />
<strong>UK</strong> <strong>NEQAS</strong> <strong>for</strong> Microbiology<br />
PO Box 63003<br />
London NW9 1GH<br />
Phone +44 (0)20 8905 9890 Fax +44 (0)20 8205 1488<br />
Hosted by the Health Protection Agency - Colindale<br />
Laboratory :<br />
Page 1 of 3<br />
Specimen 0338 <strong>Measles</strong> <strong>IgG</strong> negative <strong>Measles</strong> <strong>IgG</strong> negative 2<br />
Specimen 0339 <strong>Measles</strong> <strong>IgG</strong> positive <strong>Measles</strong> <strong>IgG</strong> positive 2<br />
Specimen 0340 <strong>Measles</strong> <strong>IgG</strong> positive <strong>Measles</strong> <strong>IgG</strong> positive 2<br />
Specimen 0341 <strong>Measles</strong> <strong>IgG</strong> positive <strong>Measles</strong> <strong>IgG</strong> positive 2<br />
Cumulative score in<strong>for</strong>mation<br />
Total number of specimens sent to you <strong>for</strong> <strong>UK</strong> <strong>NEQAS</strong> <strong>for</strong> <strong>Measles</strong> <strong>IgG</strong> <strong>serology</strong> over the last 2 distributions is 8<br />
For these distributions specimen numbers 0019 0020 0021 0338 0339 0340 0341 have been analysed and scored.<br />
Number of reports analysed 7<br />
Number of specimens reported as not examined (not scored) 0<br />
Number of specimens received too late <strong>for</strong> analysis (not scored) 0<br />
Number of specimens <strong>for</strong> which no report was received (scored as 0) 0<br />
Your cumulative score <strong>for</strong> these specimens was 14 out of a possible total of 14<br />
Your Score<br />
The mean score calculated from the reports returned by <strong>UK</strong> laboratories was 13.75 (with a standard error of 1.21).<br />
Your per<strong>for</strong>mance rating <strong>for</strong> <strong>UK</strong> <strong>NEQAS</strong> <strong>for</strong> <strong>Measles</strong> <strong>IgG</strong> <strong>serology</strong> (i.e. the number of standard errors by which your cumulative score lies above or below the<br />
mean) <strong>for</strong> <strong>UK</strong> laboratories is 0.21.<br />
A per<strong>for</strong>mance rating of more than 1.96 standard errors below the mean indicates possible poor per<strong>for</strong>mance.<br />
Your per<strong>for</strong>mance rating may change if other participants' results are amended.<br />
Per<strong>for</strong>mance Rating<br />
4<br />
3<br />
2<br />
1<br />
0<br />
-1<br />
-2<br />
-3<br />
-4<br />
Your per<strong>for</strong>mance rating over the past 3 distributions<br />
Your current per<strong>for</strong>mance rating is 0.21<br />
2654 2714 2836<br />
Distribution<br />
Turn around time: The time taken to report your results was 0 days. This in<strong>for</strong>mation is provided <strong>for</strong> your own use and does not <strong>for</strong>m part of your per<strong>for</strong>mance<br />
assessment.<br />
Comments<br />
Per<strong>for</strong>mance was very good with 98.4% of participants reporting correct results.<br />
Specimen 0338 was a negative specimen. Of the 171 participants responding 166 (97.1%) reported a negative result, 2 (1.17%) reported an equivocal result and 3<br />
(1.75%) reported a positive result.<br />
Specimens 0339, 0340 and 0341 were strong positives. Where participants used quantitative assays the following ranges of results were reported:<br />
Specimen 0338: Siemens Enzygnost: 39-150 mIU/mL, median 85 IU/mL; Virion: 81-800 mIU/mL, median 110 IU/mL.<br />
Specimen 0339: Siemens Enzygnost: 7200-13000 mIU/mL, median 9008 IU/mL; Virion: 2280-5562 mIU/mL, median 3308 IU/mL.<br />
Specimen 0340: Siemens Enzygnost: 1822-2900 mIU/mL, median 2200 IU/mL; Virion: 540-1400 mIU/mL, median 591 IU/mL.<br />
Specimen 0341: Siemens Enzygnost: 2124-3900 mIU/mL, median 3161 IU/mL; Virion: 1070-1556 mIU/mL, median 1330 IU/mL.<br />
Acknowledgements<br />
We thank colleagues at Southampton Health Protection Agency <strong>for</strong> assistance with pre-distribution testing.<br />
Enquiries<br />
For any queries about this distribution please contact Dr Brigitte Senechal at the address below.<br />
Repeat specimens can be obtained by fax +44 (0)20 8205 1488 or email organiser@ukneqasmicro.org.uk<br />
Please state your laboratory identification number, the distribution name and number and specimen number(s).<br />
All<br />
<strong>UK</strong><br />
Total score<br />
18<br />
15<br />
12<br />
9<br />
6<br />
3<br />
0<br />
Total score you achieved <strong>for</strong> each of the last 3 distributions<br />
Your current total score is 8<br />
2654 2714 2836<br />
Distribution<br />
© Copyright. The data in <strong>UK</strong> <strong>NEQAS</strong> reports are confidential.<br />
Participants must consult the scheme organiser be<strong>for</strong>e quoting data from the<br />
scheme.<br />
Published at 12:05:02 on Wednesday 13 July 2011
<strong>UK</strong> National External Quality Assessment Service <strong>for</strong> Microbiology<br />
Distribution : 2836<br />
Dispatch Date : 09-May-2011<br />
<strong>for</strong> <strong>Measles</strong> <strong>IgG</strong> <strong>serology</strong><br />
Laboratory :<br />
Page 2 of 3<br />
Four specimens were dispatched with a request to report on the presence of <strong>Measles</strong> <strong>IgG</strong> antibodies. All specimens were single donations of thrombinised human<br />
plasma.<br />
Specimen : 0338 <strong>Measles</strong> <strong>IgG</strong> negative<br />
Trinity: Captia<br />
Siemens:EIA<br />
Nova Tec<br />
Radim : EIA<br />
Bouty Technogenetics<br />
BioRad : Platelia<br />
Virotech<br />
Other<br />
Euroimmun<br />
Diesse : Chorus<br />
Virion Serion<br />
bioMerieux: Vidas<br />
0 20 40 60 80 100<br />
Number of Reports<br />
Positive Equivocal Negative<br />
Specimen : 0339 <strong>Measles</strong> <strong>IgG</strong> positive (9859 mIU/mL- Siemens Enzygnost)<br />
Trinity: Captia<br />
Siemens:EIA<br />
Nova Tec<br />
Radim : EIA<br />
Bouty Technogenetics<br />
BioRad : Platelia<br />
Virotech<br />
Other<br />
Euroimmun<br />
Diesse : Chorus<br />
Virion Serion<br />
bioMerieux: Vidas<br />
0 20 40 60 80 100<br />
Number of Reports<br />
Positive Equivocal Negative<br />
Specimen : 0340 <strong>Measles</strong> <strong>IgG</strong> positive (2928 mIU/mL- Siemens Enzygnost)<br />
Trinity: Captia<br />
Siemens:EIA<br />
Nova Tec<br />
Radim : EIA<br />
Bouty Technogenetics<br />
BioRad : Platelia<br />
Virotech<br />
Other<br />
Euroimmun<br />
Diesse : Chorus<br />
Virion Serion<br />
bioMerieux: Vidas<br />
0 20 40 60 80 100<br />
Number of Reports<br />
<strong>UK</strong> <strong>NEQAS</strong> <strong>for</strong> Microbiology<br />
PO Box 63003<br />
London NW9 1GH<br />
Phone +44 (0)20 8905 9890 Fax +44 (0)20 8205 1488<br />
Hosted by the Health Protection Agency - Colindale<br />
Positive Equivocal Negative<br />
<strong>UK</strong> (%) All (%)<br />
11 (8.8) 13 (7.3)<br />
4 (3.2) 14 (7.9)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
2 (1.6) 2 (1.1)<br />
3 (2.4) 4 (2.3)<br />
1 (0.8) 4 (2.3)<br />
0 (0.0) 6 (3.4)<br />
6 (4.8) 7 (4.0)<br />
9 (7.2) 16 (9.0)<br />
87 (69.6) 98 (55.4)<br />
<strong>UK</strong> (%) All (%)<br />
11 (8.9) 13 (7.4)<br />
4 (3.2) 14 (8.0)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
2 (1.6) 2 (1.1)<br />
3 (2.4) 4 (2.3)<br />
1 (0.8) 4 (2.3)<br />
0 (0.0) 6 (3.4)<br />
6 (4.8) 7 (4.0)<br />
9 (7.3) 16 (9.1)<br />
86 (69.4) 97 (55.1)<br />
<strong>UK</strong> (%) All (%)<br />
11 (8.9) 13 (7.4)<br />
4 (3.2) 14 (8.0)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
2 (1.6) 2 (1.1)<br />
3 (2.4) 4 (2.3)<br />
1 (0.8) 4 (2.3)<br />
0 (0.0) 6 (3.4)<br />
6 (4.8) 7 (4.0)<br />
9 (7.3) 16 (9.1)<br />
86 (69.4) 97 (55.1)<br />
Your Report : <strong>Measles</strong> <strong>IgG</strong> negative<br />
Your Score : 2<br />
Overall Results<br />
<strong>UK</strong> All Score<br />
------------------------------------------------------------<br />
<strong>Measles</strong> <strong>IgG</strong> positive 1 3 -1<br />
<strong>Measles</strong> <strong>IgG</strong> equivocal 0 2 1<br />
<strong>Measles</strong> <strong>IgG</strong> negative 121 166 2<br />
------------------------------------------------------------<br />
Total<br />
122 171<br />
% Correct<br />
99.2 97.1<br />
Your Report : <strong>Measles</strong> <strong>IgG</strong> positive<br />
Your Score : 2<br />
Overall Results<br />
<strong>UK</strong> All Score<br />
------------------------------------------------------------<br />
<strong>Measles</strong> <strong>IgG</strong> positive 122 171 2<br />
<strong>Measles</strong> <strong>IgG</strong> equivocal 0 0 1<br />
<strong>Measles</strong> <strong>IgG</strong> negative 0 0 -1<br />
------------------------------------------------------------<br />
Total<br />
122 171<br />
% Correct<br />
100 100<br />
Your Report : <strong>Measles</strong> <strong>IgG</strong> positive<br />
Your Score : 2<br />
Overall Results<br />
<strong>UK</strong> All Score<br />
------------------------------------------------------------<br />
<strong>Measles</strong> <strong>IgG</strong> positive 118 165 2<br />
<strong>Measles</strong> <strong>IgG</strong> equivocal 4 5 1<br />
<strong>Measles</strong> <strong>IgG</strong> negative 0 1 -1<br />
------------------------------------------------------------<br />
Total<br />
122 171<br />
% Correct<br />
96.7 96.5<br />
© Copyright. The data in <strong>UK</strong> <strong>NEQAS</strong> reports are confidential.<br />
Participants must consult the scheme organiser be<strong>for</strong>e quoting data from the<br />
scheme.<br />
Published at 12:05:04 on Wednesday 13 July 2011
<strong>UK</strong> National External Quality Assessment Service <strong>for</strong> Microbiology<br />
Distribution : 2836<br />
Dispatch Date : 09-May-2011<br />
<strong>for</strong> <strong>Measles</strong> <strong>IgG</strong> <strong>serology</strong><br />
Laboratory :<br />
Page 3 of 3<br />
Four specimens were dispatched with a request to report on the presence of <strong>Measles</strong> <strong>IgG</strong> antibodies. All specimens were single donations of thrombinised human<br />
plasma.<br />
Specimen : 0341 <strong>Measles</strong> <strong>IgG</strong> positive (3181 mIU/mL- Siemens Enzygnost)<br />
Trinity: Captia<br />
Siemens:EIA<br />
Nova Tec<br />
Radim : EIA<br />
Bouty Technogenetics<br />
BioRad : Platelia<br />
Virotech<br />
Other<br />
Euroimmun<br />
Diesse : Chorus<br />
Virion Serion<br />
bioMerieux: Vidas<br />
0 20 40 60 80 100<br />
Number of Reports<br />
<strong>UK</strong> <strong>NEQAS</strong> <strong>for</strong> Microbiology<br />
PO Box 63003<br />
London NW9 1GH<br />
Phone +44 (0)20 8905 9890 Fax +44 (0)20 8205 1488<br />
Hosted by the Health Protection Agency - Colindale<br />
Positive Equivocal Negative<br />
<strong>UK</strong> (%) All (%)<br />
11 (8.9) 13 (7.4)<br />
4 (3.2) 14 (8.0)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
0 (0.0) 2 (1.1)<br />
2 (1.6) 2 (1.1)<br />
3 (2.4) 4 (2.3)<br />
1 (0.8) 4 (2.3)<br />
0 (0.0) 6 (3.4)<br />
6 (4.8) 7 (4.0)<br />
9 (7.3) 16 (9.1)<br />
86 (69.4) 97 (55.1)<br />
Your Report : <strong>Measles</strong> <strong>IgG</strong> positive<br />
Your Score : 2<br />
Overall Results<br />
<strong>UK</strong> All Score<br />
------------------------------------------------------------<br />
<strong>Measles</strong> <strong>IgG</strong> positive 122 171 2<br />
<strong>Measles</strong> <strong>IgG</strong> equivocal 0 0 1<br />
<strong>Measles</strong> <strong>IgG</strong> negative 0 0 -1<br />
------------------------------------------------------------<br />
Total<br />
122 171<br />
% Correct<br />
100 100<br />
© Copyright. The data in <strong>UK</strong> <strong>NEQAS</strong> reports are confidential.<br />
Participants must consult the scheme organiser be<strong>for</strong>e quoting data from the<br />
scheme.<br />
Published at 12:05:04 on Wednesday 13 July 2011