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Product Presentation: CRP 1000

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Cell Rejuvenating Process<br />

C R P <strong>1000</strong><br />

Increasing skin renewal and regeneration<br />

EGF cytokine complex<br />

The secret of<br />

skin rejuvenation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> - Skin Repair Innovation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Developed by:<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Swiss Skin Science Labs<br />

• Swiss Public Limited Company<br />

founded in December 2004<br />

• Headquarters near Zurich / in Wetzikon<br />

(Switzerland)<br />

• Development and production of all products<br />

in Switzerland<br />

• Focused on Skin Care & Beauty<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong><br />

4


Swiss Skin Science Labs<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> Skin Repair<br />

Innovative skin repair technology from<br />

Switzerland<br />

<strong>CRP</strong> - <strong>1000</strong>. <strong>1000</strong>.<br />

is very effective for wounded<br />

skin, mature skin and impure skin. <strong>CRP</strong> a<br />

unique skin care product line, developed in<br />

Switzerland, using special technology and<br />

know how.<br />

<strong>CRP</strong> <strong>1000</strong><br />

The SKIN REPAIR Revolution!<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


MANUFACTURING - ISO 9001 : 2000 certified<br />

<strong>CRP</strong> - REPAIR PRODUCTS are manufactured under most modern<br />

facilities. Qualified personal, high standard laboratories and up-to-date<br />

know how guarantee the high quality of the <strong>CRP</strong> - SKIN REPAIR<br />

products. The manufacturing facilities are in Switzerland.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Skin rejuvenation with 1 product:<br />

<strong>CRP</strong> <strong>1000</strong> can be used as topical daily nutritive<br />

essence serum for following treatments:<br />

• Iontophoresis<br />

• Phonophoresis<br />

• Electroporation<br />

• Meso-Cosmoceutical purposes,<br />

• TDS (Transdermal Delivery System)<br />

Treatments<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> Component<br />

<strong>CRP</strong> <strong>1000</strong> includes a balanced mixture of<br />

fundamental factors in blood that help recover the<br />

normal physiology of the skin.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> Component<br />

Sterile biological solution sterile based on 8<br />

groups of active ingredients:<br />

1. Vitamins: 16 (A, E, C, D, B, K …)<br />

2. Amino acids: 24 [ arginine, hydroxyproline…]<br />

3. Minerals: Mg, Ca, Na, K<br />

4. Coenzymes: CoA, Cocarboxylase…<br />

5. Nucleic acids: DNA, RNA…<br />

6. Cytokines: EGF, bFGF<br />

7. Peptide: Copper Peptide<br />

8. Reducing Agent : Gluthation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Vitamins<br />

conc. conc.<br />

mg/L<br />

• Ascorbic Acid (vit.C) 60<br />

• Retinol (vit.A) 0,25<br />

• Menadion (vit.K) 0,025<br />

• Riboflavin (vit.B2) 0,025<br />

• Calcium pantothenate (vit.B5) 0,025<br />

• Choline (vit B7 or J) 1,25<br />

• Tocopherol (vit.E) 0,025<br />

• Calciferol (vit D2) 0,025<br />

vit. A<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Vitamins<br />

• Thiamine (vit.B1) 0,25<br />

conc. conc.<br />

mg/L<br />

• Niacin (vit. PP) 0,0625<br />

• Pyridoxine (vit.B6) 0,0625<br />

• Biotin (vit.B1) 0,025<br />

• Folic acid (vit.B9) 0,025<br />

• Vitamin B12 0,25<br />

• Aminobenzoic acid (vit.B10) 0,125<br />

• Inositol (vit.I) 0,125 vit. B1<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Amino acids conc. mg/L<br />

• Aminobutyric acid 60<br />

• Alanine 32<br />

• Glycine 14<br />

• Isoleucine 18<br />

• Methionine 4<br />

• Proline 6<br />

• Threonine 19<br />

• Valine 25<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Amino acids conc. mg/L<br />

• Aspartic acid 10<br />

• Arginine 31<br />

• Cystine 10<br />

• Hydroxyproline 4<br />

• Leucine 20<br />

• Ornithine 7<br />

• Serine 11<br />

• Trytophane 18<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Amino acids conc. mg/L<br />

• Glutamic acide 8<br />

• Asparagine 8<br />

• Glutamine 13<br />

• Histidine 20<br />

• Lysine 31<br />

• Phenylalanine 17<br />

• Taurine 4<br />

• Tyrosine 16<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Minerals conc. conc.<br />

mg/L<br />

• Calcium 200<br />

• Potassium 400<br />

• Magnesium 100<br />

• Sodium 6600<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Coenzymes conc. conc.<br />

mg/L<br />

• Coenzyme A 2,50<br />

• Cocarboxylase 1<br />

• NAD 7<br />

• FAD 1<br />

• NADP 1<br />

• UTP 1<br />

(NAD+)<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Nucleic acids conc. conc.<br />

mg/L<br />

• Deoxyadenosine 10<br />

• Deoxycystidine 10<br />

• Methylcytosine 0,1<br />

• Deoxyguanosine 10<br />

• Thymidine 10<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Cytokines conc. conc.<br />

mg/L<br />

Cytokines<br />

• Epidermal Growth Factor (EGF) 1<br />

• basic Fibroblast Growth Factor (bFGF) 1<br />

EGF bFGF<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Peptide conc. conc.<br />

mg/L<br />

• Copper peptide 10<br />

Reducing Agent conc. conc.<br />

mg/L<br />

• Gluthation 10<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Biological effects of <strong>CRP</strong> <strong>1000</strong><br />

• Vitamins provide an anti-deficiency function<br />

• Amino acids a better protein construction<br />

• Minerals guarantee the ionic balance<br />

• Co-enzymes activate the biochemical reactions<br />

• Nucleic acids stimulate synthesis<br />

• Cytokines (EGF, bFGF) stimulate cell functions in aged skin<br />

• Copper Peptid increases biosynthesis of collagen and elastin<br />

• Reducing Agent Gluthation : Super anti-oxidant created from liver<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


In vitro study<br />

Evaluation of the cellular stimulation properties of<br />

<strong>CRP</strong> <strong>1000</strong> on human skin fibroblasts<br />

• +11% ~ +30% after 72 hours<br />

• +12% ~ +37% after 168 hours<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Rejuvenating<br />

40<br />

30<br />

20<br />

10<br />

!"#$%&'"'()*+(*,-+(*.+$"('//*0(1*230/)+4+)5*678*9:)'$*;


Wound healing<br />

160<br />

155<br />

150<br />

145<br />

140<br />

135<br />

,)+"=30)+%(*%:*B%330>'(*,5()F'/+/<br />

6B%330>'(*2H!,98<br />

400 800 1600 10%<br />

?@A7*B5)%-+('/*4%"#3'C*/)+"=30)'/*B%330>'(*,5()F'/+/<br />

B%(4'()$0)+%(*6#>G"38<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Rejuvenating<br />

20<br />

15<br />

10<br />

5<br />

.%$"=30)+%(*4%()0+(+(>*6?@A7B5)%<br />

-+('/*4%"#3'C8<br />

Cytokines complex Induces Increase in Ski<br />

n Smoothness<br />

40<br />

30<br />

20<br />

10<br />

.%$"=30)+%(*4%()0+(+(><br />

6?@A7B5)%-+('/*4%"#3'C8<br />

Within 4 weeks, wrinkle depth was re<br />

duced by about 30%<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Regeneration<br />

<strong>CRP</strong> <strong>1000</strong> restores the natural skin repair<br />

mechanism.<br />

1. <strong>CRP</strong> <strong>1000</strong> induces the proliferation and<br />

reconstitutes the optimum functional capability<br />

of prematurely senescent fibroblasts.<br />

2. <strong>CRP</strong> <strong>1000</strong> facilitates the reconstruction of the<br />

cutaneous architecture through an active<br />

action on collagen fibres.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Regeneration<br />

1. Action on Fibroblasts<br />

- Fibroblast Growth Factor – like activity<br />

- Favors the correct assembly of the fibronectin<br />

extra cellular matrix.<br />

BEFORE AFTER<br />

- Cultured senescent fibroblasts acquiring an arrangement<br />

and morphology similar to those of young fibroblasts.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Regeneration<br />

2. Reconstruction of cutaneous architecture<br />

- Collagenase activity on denatured collagen<br />

- Copper Peptide activity on increase of biosynthesis of<br />

collagen and elastin<br />

- Provides a structural support network of fibronectin<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Protection<br />

<strong>CRP</strong> <strong>1000</strong> potentates the protective mechanism of<br />

the skin<br />

- Reducing agent Gluthation : Super anti-oxidant<br />

created from liver<br />

- Reinforced with antioxidant : Vit C, Vit E<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination Treatment<br />

<strong>CRP</strong> <strong>1000</strong> can be used as<br />

topical daily nutritive essence<br />

serum.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination with TDS<br />

(Transdermal<br />

Transdermal Delivery System) Treatment<br />

<strong>CRP</strong> <strong>1000</strong><br />

with Iontophoresis<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination with TDS<br />

(Transdermal<br />

Transdermal Delivery System) Treatment<br />

<strong>CRP</strong> <strong>1000</strong><br />

with Phonophoresis<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination with Meso Gun or Needel<br />

(Transdermal<br />

Transdermal Delivery System) Treatment<br />

<strong>CRP</strong> <strong>1000</strong><br />

and Mesotherapy<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination with TDS<br />

(Transdermal<br />

Transdermal Delivery System) Treatment<br />

<strong>CRP</strong> <strong>1000</strong><br />

with Electroporation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination Treatment<br />

<strong>CRP</strong> <strong>1000</strong> can be used as topical daily nutritive<br />

essence serum after peeling (laser peel, chemical<br />

peel, dermabrasion, etc.).<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Combination Treatment<br />

<strong>CRP</strong> <strong>1000</strong> can be compatible with botox ® treatment<br />

and with fillers (Matridex, Matredur, etc.).<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


A natural activator of repair and<br />

regeneration of skin damaged by:<br />

Topical Retinoids<br />

Repairs skin problems caused by retinoids,<br />

restoring skin integrity.<br />

- For acne (both male and female skin)<br />

- Photoaging<br />

- Eyes and lip contour<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


A natural activator of repair and<br />

regeneration of skin damaged by:<br />

• Ablative and non-ablative rejuvenation techniques<br />

• Post-treatment care for rapid cutaneous repair<br />

• Post-treatment care for Laser and peeling techniques<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


A natural activator of repair and<br />

regeneration of skin damaged by:<br />

Photoaging<br />

Reactivate natural skin regeneration, improving cell<br />

functionality<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Before and after pictures with<br />

<strong>CRP</strong> <strong>1000</strong> and TDS:<br />

<strong>CRP</strong> <strong>1000</strong> + BioViso<br />

Result after 4 treatments with<br />

<strong>CRP</strong> and electrotherapy<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Before and after pictures with<br />

<strong>CRP</strong> <strong>1000</strong> and TDS:<br />

<strong>CRP</strong> <strong>1000</strong> + BioViso<br />

Result after 4 treatments with<br />

<strong>CRP</strong> and electrotherapy<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Before and after pictures with<br />

<strong>CRP</strong> <strong>1000</strong> and TDS:<br />

<strong>CRP</strong> <strong>1000</strong> + Acthyderm<br />

Result after 5 treatments with <strong>CRP</strong> and<br />

BioCell, BioCell,<br />

application with electroporation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Before and after pictures with<br />

<strong>CRP</strong> <strong>1000</strong> and TDS:<br />

<strong>CRP</strong> <strong>1000</strong> + Acthyderm<br />

Result after 6 treatments with <strong>CRP</strong> and<br />

BioCell , application with elecptroporation<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


A NEW DUAL TREATMENT<br />

OFFERING AN INTEGRAL<br />

SOLUTION TO HAIR LOSS<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> Profile<br />

- Anti-hair loss<br />

- Balanced combination of renowned,<br />

effective and innovative components<br />

in high concentrations<br />

- Patients profile<br />

Patients with all type of Alopecias<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


ALOPECIAS<br />

- Alopecia is a source of constant investigation<br />

- Alopecia is an important concern for dermatologists<br />

- First treatments were targeted to prevent hair loss only.<br />

- New elements were introduced to stimulate hair growth<br />

- Nowadays, a proper treatment is expected to also protect hair<br />

structure and integrity.<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong><br />

A balanced and comprehensive combination of highly effective and<br />

innovative components able to act against all factors promoting hair loss.<br />

- Acts on the hair life cycle at different levels.<br />

Prevents hair<br />

loss<br />

Normalizes<br />

hair grease<br />

secretion<br />

Stimulates<br />

hair growth<br />

Protects hair<br />

structure &<br />

integrity<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Prevents hair loss<br />

- Prevents the death of<br />

hair follicle<br />

- Normalizes hair greasy<br />

- Prevents the<br />

miniaturization of the<br />

bulb and the death of the<br />

hair follicle<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Protect hair integrity<br />

Protect hair integrity<br />

- Enzimatic activity against Superoxide Anions(O-) inhibits<br />

lipid peroxidation<br />

- Vitamin C: Hydrosoluble antioxidant<br />

- Vitamin E: Liposoluble antioxidant<br />

- Reducing agent Gluthation : Super anti-oxidant created from<br />

liver<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


<strong>CRP</strong> <strong>1000</strong> the most innovative<br />

skin repair product ever created!<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Cell Rejuvenating Process<br />

C R P <strong>1000</strong>


Cell Rejuvenating Process<br />

C R P <strong>1000</strong><br />

Increasing skin renewal and regeneration<br />

EGF cytokine complex<br />

Thank you<br />

for your attention<br />

Cell Rejuvenating Process<br />

C R P <strong>1000</strong>

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