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Membrane Technology for Enzyme Separations - NBV

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<strong>Membrane</strong> <strong>Technology</strong> <strong>for</strong> <strong>Enzyme</strong> <strong>Separations</strong><br />

DSM<br />

Cefalexin Green Alternative (CEGA)<br />

O<br />

H NH 2<br />

Enzymatic production process <strong>for</strong> Cefalexin<br />

Start-up Start up: : 1997 in Barcelona<br />

NH 2<br />

+<br />

H 2N<br />

O<br />

H H<br />

N<br />

S<br />

CO 2<br />

Pen-G-acylase<br />

H 2 O<br />

O<br />

H NH2<br />

Phenylglycine amide 7-ADCA ADCA Cefalexin<br />

H<br />

N<br />

O<br />

H H<br />

N<br />

S<br />

CO 2

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