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2006 Updates Clinical Practice Guidelines and Recommendations

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y KDOQI (spKt/V � 1.3 per dialysis), but the rationale for increasing the target was not<br />

clearly delineated. The group recommended using the mean of creatinine <strong>and</strong> urea clearance<br />

as a measure of RKF <strong>and</strong> discouraged twice-weekly dialysis.<br />

In the United States, we have come a long way, from marveling about how HD can<br />

snatch patients from the jaws of death <strong>and</strong> keep them alive indefinitely to coping with<br />

0.1% of the population depending on HD for life support. Nephrologists have learned<br />

that, although numbering more than 300,000, these patients represent a small segment<br />

of approximately 20 million people in the United States with kidney disease who have<br />

survived tremendous risks for CVD <strong>and</strong> other morbid diseases to develop CKD stage 5.<br />

They often arrive in the dialysis clinic with a legacy of diabetes, CVD, <strong>and</strong> inflammatory<br />

diseases that continue to progress. The challenge for today’s health care workers <strong>and</strong> the<br />

dialysis industry is to provide an opportunity for these patients to live long <strong>and</strong> comfortably<br />

with freedom to pursue their dreams, even if for only a relatively short length of time<br />

in those at high risk. We need to be all things for these patients, but first <strong>and</strong> foremost,<br />

we must deliver the best dialysis therapy we can with available technology. These new<br />

KDOQI HD CPGs, CPRs, <strong>and</strong> Research <strong>Recommendations</strong> are designed to provide a<br />

clearer pathway <strong>and</strong> help everyone move in that direction.<br />

KDOQI National Kidney Foundation 15

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