Anja E. Hauser - NeuroCure

Anja E. Hauser
Deutsches Rheuma-Forschungszentrum Berlin (DRFZ)
Charitéplatz 1 | D-10117 Berlin
Phone: +49 (0)30 28460-238
E-mail: hauser@drfz.de
Curriculum vitae
Since 2012 Professor (W3), Intravital Imaging and Immune Dynamics, Charité
2008-2012 Group leader “Immune Dynamics”, DRFZ Berlin
2004-2008 Postdoctoral fellow (Advisor: Prof. M. Shlomchik), Yale University, New Haven, USA
2003-2004 Postdoctoral associate (Advisor: Prof. R. Manz), DRFZ Berlin
2000-2003 PhD thesis, Freie Universität Berlin and Deutsches Rheumaforschungszentrum
1993-1999 Studies of Veterinay Medicine, Tierärztliche Hochschule Hannover
Research fields
Our lab is interested in the dynamics of immune system in health and disease. In order to investigate
immune responses, we are using intravital multiphoton microscopy which
allows us to analyze cell migration and interactions in vivo.
We are focussing on
• B cell responses
• Immune dynamics in neuroinflammation
• Interactions between lymphocytes and stromal cells
• Mucosal immunity
Activities in the scientific community, honors, awards
2012 JIMI-a network for intravital microscopy, co-founder
2003 Avrion Mitchison Award for Rheumatology

Selected publications
Andresen V.*, Pollok K.*, Rinnenthal J.L., Oehme L., Günther R., Spiecker H., Radbruch H., Gerhard
J., Sporbert A,. Cseresnyes Z., Hauser A.E.*, Niesner R.* (2012). High-resolution intravital microscopy.
PloSOne, in press
Niesner, R.A., and Hauser, A.E. 2011. Recent advances in dynamic intravital multi-photon microscopy.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 79:789-798
Lin, G.H., Edele, F., Mbanwi, A.N., Wortzman, M.E., Snell, L.M., Vidric, M., Roth, K., Hauser, A.E., and
Watts, T.H. (2012). Contribution of 4-1BBL on radioresistant cells in providing survival signals through
4-1BB expressed on CD8+ memory T cells in the bone marrow. European journal of immunology 42,
2861-2874.
Esplugues E., Huber, S. Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O’Connor Jr., W., Rongvaux,
A., Van Rooijen, N., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold,
K. C., and Flavell, R. A. (2011) Control of Th17 cells occurs in the small intestine. Nature 475, 514-518
Kohler, A., De Filippo, K., Hasenberg, M., van den Brandt, C., Nye, E., Hosking, M.P., Lane, T.E., Mann,
L., Ransohoff, R.M., Hauser, A.E., Winter, O., Schraven, B., Geiger, H., Hogg, N., and Gunzer, M.
(2011). G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone
marrow via induction of Cxcr2 ligands. Blood 117, 4349-4357.
Hiepe, F., Dorner, T., Hauser, A.E., Hoyer, B.F., Mei, H., and Radbruch, A. (2011). Long-lived autoreactive
plasma cells drive persistent autoimmune inflammation. Nat Rev Rheumatol 7, 170-178.
Hauser, A.E., Kerfoot, S.M., and Haberman, A.M. (2010). Cellular choreography in the germinal center:
new visions from in vivo imaging. Semin Immunopathol 32, 239-255.
Herz, J., Siffrin, V., Hauser, A.E., Brandt, A.U., Leuenberger, T., Radbruch, H., Zipp, F., and Niesner,
R.A. (2010). Expanding two-photon intravital microscopy to the infrared by means of optical parametric
oscillator. Biophys J 98, 715-723.
Hauser, A.E., Shlomchik, M.J., and Haberman, A.M. (2007). In vivo imaging studies shed light on
germinal-centre development. Nat Rev Immunol 7, 499-504
Hauser, A.E., Junt, T., Mempel, T.R., Sneddon, M.W., Kleinstein, S.H., Henrickson, S.E., von Andrian,
U.H., Shlomchik, M.J., and Haberman, A.M. (2007). Definition of germinal-center B cell migration in vivo
reveals predominant intrazonal circulation patterns. Immunity 26, 655-667.
*equal contribution
Appendices