Stroke During TAVI: An Unmet Clinical Need? - Paragon Conventions

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Mechanisms of Stroke during TAVI – Balloon valvuloplasty • Stroke rates in literature range from 1-5% Cribier A,Percutaneous transluminal valvuloplasty of acquired aortic stenosis in elderly patients: an alternative to valve replacement? Lancet. 1986;1:63-67. Safian RD, Balloon aortic valvuloplasty in 170 consecutive patients. N Engl J Med. 1988;319:125- 130. Otto CM, Mickel MC, Kennedy JW, et al. Three year outcome after balloon aortic valvuloplasty: insights into prognosis of valvular aortic stenosis. Circulation. 1994;89:642-650. Eltchaninoff H, Cribier A, Tron C, et al. Balloon aortic valvuloplasty in elderly patients at high risk for surgery or inoperable. Immediate and mid-term results. Eur Heart J. 1995;16:1079-1084. Pedersen WR, Klaassen PJ, Boisjolie CR, et al. Feasibility of transcatheter intervention for severe aortic stenosis in patients > 90 years of age: aortic valvuloplasty revisited. Cathet Cardiovasc Interv. 2007;70:149-154.
Mechanisms of Stroke during TAVI – Catheter Thrombosis • Long periods of valve repositioning in difficult cases • Pigtail catheter thrombosis • Trade off in anticoagulation between stroke risk and vascular complications from closure device failure • Ideal ACT for procedure?
Page 1 and 2: Stroke During TAVI: An Unmet Clinic
Page 3 and 4: Stroke prevention in TAVI: An unmet
Page 5: Stroke is still a major source of c
Page 9 and 10: The Source Registry
Page 11 and 12: New Perspectives on Stroke During T
Page 13 and 14: Study design Evaluation Clinical an
Page 15 and 16: DW - MRI
Page 17 and 18: NIH-Stroke Score 20 18 16 4 2 0 NIH
Page 19 and 20: What about Transfemoral vs Transapi
Page 21 and 22: DW-MRI Results Post TAVI
Page 23 and 24: Neurological and Cognitive Test Res
Page 25 and 26: Significance of MRI lesions? • No
Page 27 and 28: Mechanisms of Stroke during TAVI -
Page 29 and 30: Mechanisms of Stroke during TAVI -
Page 31: Mechanisms of Stroke during TAVI -
Page 35 and 36: What can we do stop the shower?
Page 37 and 38: Brachiocephalic trunk Cerebral Filt
Page 39 and 40: Embolic Material
Page 41 and 42: Embrella Embolic Deflector • Poro
Page 43 and 44: Embrella Case Example
Page 45 and 46: Embrella Case Example
Page 47 and 48: Embrella Clinical Experience
Page 49 and 50: Average number of Lesions/Subject
Page 51 and 52: Aortic Embolic Protection Device (
Page 53 and 54: Post TAVI Antiplatelet Therapy •

Stroke During TAVI: An Unmet Clinical Need? - Paragon Conventions

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