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Benchmarking Physician Prescribing Against True ... - IMS Health

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<strong>Benchmarking</strong> <strong>Physician</strong> <strong>Prescribing</strong><br />

<strong>Against</strong> <strong>True</strong> Business Potential<br />

BENEFIT DESIGNS REVEAL IMPACT OF PATIENTS COSTS<br />

Pharmaceutical companies routinely turn to insurance plan<br />

formularies to understand performance drivers for their products. But<br />

individual benefit designs under the plan are contracted at the local<br />

level, where premiums, co-pays, and tier status are negotiated by<br />

employer groups. In this environment, the formulary information tied<br />

to a national plan does not provide the level of insight necessary to<br />

uncover real prescriber access — often creating missed opportunities<br />

or inefficient resource allocation.<br />

It is now possible to explore the “why” behind product<br />

performance within plan designs by better understanding the<br />

competitive context — the cost differentials and options available<br />

to the patient and prescribing physician. <strong>IMS</strong> recently conducted<br />

an analysis of the angiotensin receptor blocker (ARB) market that<br />

reveals how visibility into the co-pay structures that drive patient<br />

behavior can contravene what companies believe they know about<br />

an individual physician’s prescribing potential.<br />

THE STUDY DESIGN<br />

The ARB market is highly commoditized. For this study,<br />

<strong>IMS</strong> selected the lens of AVAPRO ® , one of many products<br />

in the category. The analysis covered the top 150 prescribers<br />

in the commercial Chicago metro territory, based on ARB<br />

market volume for one quarter in 2010.<br />

Rx BENEFIT DESIGN<br />

CASE STUDY<br />

VISIBILITY INTO VARIABILITY<br />

Employer-based plans impact product access and price and<br />

influence patient behavior. Until now, pharmaceutical companies<br />

have lacked sufficient visibility into local plan designs,<br />

many of which do not follow national published plans.<br />

<strong>IMS</strong> Rx Benefit Design provides insight into the actual copay<br />

structures — those that are constructed for employers<br />

within each plan, payer, and PBM. Patient choices can be<br />

understood in the context of cost differentials, or what the<br />

patient might have paid through another option.<br />

This solution enables improved contracting, resource<br />

allocation, targeting, segmentation, and messaging.<br />

Rx Benefit Design provides the most granular information<br />

available to evaluate physician prescribing and patient use<br />

for a product. For this analysis, <strong>IMS</strong> calculated brand shares<br />

within the overall plan as well as in each plan benefit design<br />

for comparison. <strong>IMS</strong> then calculated an opportunity share for<br />

each prescriber.


BEYOND THE FORMULARY<br />

With <strong>IMS</strong> Xponent PlanTrak ® , <strong>IMS</strong> first evaluated subnational<br />

performance by plan. AVAPRO has an above<br />

average share in the Chicago territory and an even higher<br />

share in the top plan in the territory, Blue Cross Blue<br />

Shield (BCBS) of Illinois. (The preferred brands within this<br />

PPO are BENICAR ® and DIOVAN ® . )<br />

The analysis showed that 17 percent of AVAPRO volume for<br />

the BCBS PPO was through a 2-tier structure. This finding<br />

reveals that the assumption that tier status alone reflects<br />

therapeutic options available to patients does not<br />

necessarily hold true. It also refutes the commonly held<br />

belief that 2-tier designs are predominantly closed and thus<br />

provide very little opportunity for non-preferred brands.<br />

Performance of preferred brands also varies across multitiered<br />

benefit designs, as observed by an analysis of co-pay<br />

differentials available through Rx Benefit Design. AVAPRO<br />

and DIOVAN, for instance, mirrored what <strong>IMS</strong> has seen in<br />

almost every market studied: As co-pay differentials (i.e.,<br />

difference between tier 2 and tier 3 co-pays) decrease, the<br />

transaction shares of those drugs move closer together. (See<br />

Figure 1). For example, the non-preferred drug AVAPRO is<br />

only 2.3 percentage points lower than the preferred market<br />

leader Diovan when the differential is $15, compared to a<br />

FIG. 1: CO-PAY DIFFERENTIALS DRIVE<br />

PATIENT CHOICE<br />

BCBS-IL<br />

TRx Share<br />

35.0%<br />

30.0%<br />

25.0%<br />

20.0%<br />

15.0%<br />

10.0%<br />

5.0%<br />

28.9%<br />

4.8%<br />

17.6%<br />

7.5%<br />

— Avapro — Diovan<br />

13.7%<br />

11.4%<br />

0.0%<br />

$20-$50 $30-$50 $20-$35<br />

24.1 percentage point gap when the differential is $30. This<br />

finding is significant for a competitor to the dominant<br />

drug in the category.<br />

PHYSICIAN-LEVEL OPPORTUNITIES<br />

<strong>Physician</strong> performance can also be evaluated within the<br />

context of benefit design. As indicated in physician-level<br />

Xponent PlanTrak data, AVAPRO’s share is significantly<br />

different across the top prescribers in the top local plan,<br />

ranging from 0 percent to 31 percent. The volume for<br />

the top writer with no AVAPRO prescriptions is highly<br />

concentrated in BCBS-IL PPO (60 percent). Despite the<br />

fact that AVAPRO is not a preferred drug, Rx Benefit<br />

Design shows that 31 percent of the benefit design volume<br />

for this physician is advantageous for AVAPRO (18 percent<br />

from the $20/$30 co-pay category in which AVAPRO<br />

does well and 13 percent from the $15 2-tier design).<br />

(See Figure 2).<br />

After identifying such opportunities for growth within a<br />

plan for a product with relatively poor formulary position,<br />

the company can re-evaluate physician targeting, call plans,<br />

frequency, messaging and resource allocation, including<br />

sampling. Providing a doctor with information on patients’<br />

willingness to pay within certain design structures can be a<br />

value-add. Such insight also may be used in goal setting for<br />

the field force.<br />

<strong>Benchmarking</strong> at the level of granularity provided by Rx<br />

Benefit Design enables the company to compare a given<br />

physician’s prescription volume (11.1 percent in the case<br />

shown in Figure 3) to the shares within each specific design<br />

rather than solely to the overall plan volume (8.3 percent).<br />

AVAPRO performance is strong in the $30_$50 design and<br />

shows potential for growth in the $20_$35 design.<br />

Across the entire territory in the Chicago area, the analysis<br />

uncovered 45 prescribers for whom the prescribing<br />

opportunity had been understated and another 44 for<br />

whom the opportunity had been overstated prior to the<br />

benchmarking done with Rx Benefit Design. This is a<br />

significant change in potential resource allocation for one<br />

territory, which will result in a much higher ROI by<br />

focusing effort on prescribers with true potential.


FIG. 2: CO-PAY STRUCTURES<br />

REPRESENT HIDDEN POTENTIAL<br />

� OTHER (3) 14%<br />

� AETNA IL 5%<br />

� COUNTY HEALTH 5%<br />

� MEDCO 7%<br />

� FEPBLUE 9%<br />

THE ULTIMATE ROI<br />

Such analyses, which increase the accuracy of physician<br />

benchmarking, finally reveal the true impact of managed<br />

care. The data can be leveraged for goal setting, targeting,<br />

segmentation and monitoring sales force performance.<br />

Benefit design details can put the performance of individual<br />

physicians in a new light, revealing that some have greater<br />

FIG. 3: MORE ACCURATE BENCHMARKING BASED ON TRUE POTENTIAL<br />

Plan<br />

Benchmark<br />

Avapro BCBS-IL<br />

Plan Rx Benefit<br />

Design Benchmarks<br />

Avapro BCBS-IL in<br />

each Rx Benefit Design<br />

<strong>Physician</strong> 13434 TRx by Plan<br />

$30_$50<br />

7.4%<br />

20.7%<br />

Potential for Avapro<br />

31% of the BCBS-IL plan volume for<br />

this Dr is advantageous for Avapro<br />

BCBS-IL<br />

(PPO) 60%<br />

Avapro<br />

8.3%<br />

$40_$60<br />

0.2%<br />

0.0%<br />

BCBS-IL<br />

potential than had been assumed and that others, previously<br />

viewed as under-performers, are indeed prescribing to their<br />

full potential. Whether expectations are realistically reduced<br />

or dramatically raised, the results are the same: optimized<br />

resources and the highest possible return. ●<br />

For more information, call 800.523.5333 or contact<br />

your <strong>IMS</strong> representative.<br />

$20_$35<br />

11.4%<br />

0.0%<br />

11.1%<br />

25%<br />

20%<br />

15%<br />

10%<br />

5%<br />

0%<br />

BCBS-IL by Benefit Design<br />

21%<br />

$40_$60<br />

18% 16%<br />

$20_$35<br />

$25_$50<br />

Dr 75318<br />

Avapro<br />

Shares<br />

13%<br />

$15<br />

9% 6%<br />

$30_$50<br />

$20_$50<br />

17%<br />

Other<br />

Benefit<br />

Designs (5)


ABOUT <strong>IMS</strong> HEALTH<br />

Operating in more than 100 countries, <strong>IMS</strong> <strong>Health</strong><br />

is the world’s leading provider of market intelligence<br />

to the pharmaceutical and healthcare industries.<br />

With more than 55 years of industry experience,<br />

<strong>IMS</strong> <strong>Health</strong> offers leading-edge market intelligence<br />

products and services that are integral to clients’ dayto-day<br />

operations, including product and portfolio<br />

management capabilities; commercial effectiveness<br />

innovations; managed care and consumer health<br />

offerings; and consulting and services solutions that<br />

improve productivity and the delivery of quality<br />

healthcare worldwide.<br />

<strong>IMS</strong> HEALTH®<br />

200 Campus Drive<br />

Collegeville, PA 19426<br />

800.523.5333<br />

www.imshealth.com<br />

© 2011 <strong>IMS</strong> <strong>Health</strong> Incorporated or its affiliates. All Rights Reserved. 11070-A

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