Safety of antibody drug conjugates
Safety of antibody drug conjugates
Safety of antibody drug conjugates
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Concentrations <strong>of</strong> measured analytes following a 30<br />
mg/kg dose <strong>of</strong> T-DM1 to cynomolgus monkeys<br />
Concentration (!g/mL)<br />
10000<br />
1000<br />
100<br />
10<br />
1<br />
0.1<br />
0.01<br />
0.001<br />
0.0001<br />
females<br />
0 21 42 63 84 105<br />
Time (day)<br />
Total Tmab<br />
T-DM1<br />
DM1<br />
Genentech, Inc.