Dengue Bulletin
Dengue Bulletin
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involvement (8) . This elevation of liver enzyme<br />
may possibly be related to the increased<br />
drug usage or to shock or other factors that<br />
would need to be studied further. This<br />
abnormal elevation of AST in most suspected<br />
cases of dengue infection may be used as an<br />
early indicator of dengue illness as suggested<br />
earlier (6) .<br />
References<br />
1. Nimmannitya S. Clinical manifestations and<br />
2.<br />
management of dengue/dengue haemorrhagic<br />
fever. In: Thongchareon P. ed. Monograph on<br />
dengue/dengue haemorrhagic fever. New Delhi:<br />
WHO Regional Office for South-East Asia, 1993:<br />
48-54, 55-61.<br />
Anonymous. Annual morbidity and mortality<br />
reports of the Division of Epidemiology, Office of<br />
the Permanent Secretary, Ministry of Public<br />
Health, 1958-2001.<br />
3. Nimmannitya S. <strong>Dengue</strong> haemorrhagic fever:<br />
Diagnosis. In DJ Gubler and G Kuno (eds). <strong>Dengue</strong><br />
and dengue haemorrhagic fever. CAB<br />
4.<br />
International, 1997: 133-145.<br />
WHO. <strong>Dengue</strong> haemorrhagic fever: Diagnosis,<br />
treatment, prevention and control. 2nd edition.<br />
Geneva, 1997.<br />
5. Halstead SB. Pathophysiology and pathogenesis of<br />
dengue haemorrhagic fever. In: Thongchareon P<br />
ed. Monograph on dengue/dengue haemorrhagic<br />
fever. New Delhi: WHO Regional Office for<br />
South-East Asia, 1993: 80-103.<br />
<strong>Dengue</strong> Patients at the Children’s Hospital, Bangkok: 1995-1999 Review<br />
Acknowledgements<br />
We are grateful to the AFRIMS for their<br />
continuing serological and virological<br />
laboratory support. This study was a part of<br />
the project “Clinical database management”<br />
at the Queen Sirikit National Institute of<br />
Child Health (Children’s Hospital) which was<br />
funded by UNCINPAC through the AFRIMS.<br />
6. Kalayanarooj S, Vaughn DW, Nimmannitya S,<br />
Green S, Suntayakorn S, Kunentrasai N,<br />
7.<br />
Viramitrachai W, Ratanachu-eke S, Kiatpolpoj S,<br />
Innis BL, Rothman AL, Nisalak A and Ennis FA.<br />
Early clinical and laboratory indicators of acute<br />
dengue illness. JID, 1997, 176: 313-21.<br />
Kalayanarooj S, Nimmannitya S, Suntayakorn S,<br />
Vaughn DW, Nisalak A, Green S, Chansiriwongs<br />
V, Rothman A and Ennis FA. Can doctors make an<br />
accurate diagnosis of dengue? <strong>Dengue</strong> <strong>Bulletin</strong>,<br />
1999, 23: 1-9.<br />
8. Kalayanarooj S and Nimmannitya S. Clinical and<br />
laboratory presentations of dengue patients with<br />
different serotypes. <strong>Dengue</strong> <strong>Bulletin</strong>, 2000, 24:<br />
53-59.<br />
<strong>Dengue</strong> <strong>Bulletin</strong> – Vol 26, 2002 43