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<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> 2008 3


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Editorial<br />

<strong>The</strong> song goes on<br />

Robert Atnip, MD<br />

<strong>The</strong> author (AΩA, University of Alabama, 1976)<br />

is a member of the board of directors of <strong>Alpha</strong><br />

<strong>Omega</strong> <strong>Alpha</strong>.<br />

am an academic vascular surgeon, a senior fac-<br />

I ulty member at a University Hospital, a mentor<br />

of medical students and residents, and a teacher<br />

of professionalism. My own lessons in professionalism<br />

came while in medical school, but<br />

not in any classroom or book. I don’t recall the<br />

word even being spoken during those four years<br />

(1974–78). No doubt some of those who modeled<br />

it for me were physicians, but in retrospect, the<br />

most influential person was no doctor, but a musician.<br />

That music has the power to pervade the human experience<br />

may be a mystery, but it is no secret. Music is as universal<br />

as the human senses, and as vital. As a form of human<br />

expression, music is at the same time both elemental and<br />

transcendent. It is one of humanity’s finest gifts to itself, a<br />

gift that to our lament cannot be as readily celebrated in <strong>The</strong><br />

<strong>Pharos</strong> as the visual and literary arts. Music is not for speaking<br />

or writing. Music is ineffable emotion, a sequence of nameless<br />

swells and surges that defy the bounds of speech. Our voices<br />

are put to much better use making music than describing it<br />

and, in like manner, professionalism is much less a creed to<br />

be discerned and codified than it is a craft to be realized and<br />

enacted. <strong>The</strong>rein lies the basis for choral music to instruct me<br />

in the finer points of professionalism.<br />

Nowadays, professionalism is a paramount concern to the<br />

health care world, but it was not always so. “Professionalism”<br />

was irrelevant to academia prior to 1965. My search for “professionalism”<br />

as a key word in OLD_OVID (1947–65) returned<br />

only the red-lettered retort, “Unable to match with any subject<br />

heading.” In the fifteen years that followed, “professionalism”<br />

made its debut with 180 appearances, the majority in nursing<br />

journals or, oddly enough, in the dentistry literature. But only<br />

in the last thirty years has “professionalism” gained enough<br />

traction to merit the eight subject headings to which it now<br />

maps in OVID, the thousands of publications devoted to<br />

probing its obliquities, or the several awards and grants now<br />

bestowed in its name by prestigious societies such as ours.<br />

This logarithmic progression is extraordinary for a concept<br />

that acquired its name as long ago as the fourteenth<br />

century. Toward the end of the so-called Dark Ages, the word<br />

“profess” appeared among religious orders with the meaning<br />

“to take a vow,” or “to declare [a belief] publicly.” This definition<br />

and related word forms served adequately, perhaps even<br />

admirably, throughout all subsequent ages of history and into<br />

modern times. Only in the post-Modern era has the simplicity<br />

and sparse eloquence of these phrases come to be viewed as<br />

inadequate for today’s professionals. But I think what may be<br />

lacking is not the words, but the . . . music!<br />

And so in the mid-1970s, modern professionalism’s “early<br />

years,” I came upon my unwitting mentor-to-be while in medical<br />

school in Birmingham, Alabama. Having enjoyed music<br />

and singing as a youth, and wanting some activity<br />

beyond the confines of studying anatomy<br />

and physiology, I met JWS, the organist and<br />

choirmaster at a local church. <strong>The</strong> meeting<br />

was happenstance, but serendipity has never<br />

worked any better magic than this. I joined and<br />

sang in his choir, as much an amateur singer as<br />

I was a fledgling doctor. But the experience was<br />

profound, a turning point for me, and a revelation<br />

of new worlds. For the next three years this<br />

choir became as important to me as my medical<br />

education. Under the direction of JWS, or more<br />

properly, under his spell, I learned what it is to<br />

“profess” choral music: to blend many voices into one sound,<br />

the music built on every voice, but ever greater than any one<br />

alone; to tune each voice and phrase toward perfection; to purify<br />

many harmonies into one great and coherent beauty. <strong>The</strong><br />

sounds and the music were exquisite, many of them recorded<br />

at that time, and still inspiring to me more than thirty years<br />

later. To listen to them is to understand the fruits of professionalism<br />

and, moreover, to discern therein a startling similarity<br />

to what we seek to do in the individual and corporate acts<br />

of medical practice.<br />

This connection of music to medicine may seem obscure to<br />

some, and self-evident to others. But I contend that the truths<br />

learned in the making of music are the same truths that we<br />

who profess medicine must teach our students, and re-affirm<br />

for ourselves: competence, discipline, determination, focus,<br />

artistry, the seeking of common goals, the drive to excel, the<br />

ability to lead and to follow, and one perhaps not as obvious:<br />

aesthetics—the presence of beauty and inner harmony in what<br />

we do. I do not equate humanism with professionalism, but<br />

they have much in common. <strong>The</strong>y are separate yet inseparable,<br />

linked by a common need for each to nourish the other. I was<br />

most fortunate at a remarkable and formative time of my life to<br />

be in a milieu suffused with an abundance of each. To those who<br />

cleared this path for me, I owe an inexpressible debt. <strong>The</strong>y knew<br />

that professionalism has not only a body, but a soul.<br />

It was never my destiny to become a professional musician,<br />

but I am delighted to be a musical professional. Music may not<br />

have made me a better medical scientist, but it has made me a<br />

better physician. Vita brevis, ars longa. To the extent that we<br />

are true to our identity as healers, then we must—in concert<br />

with advances in science and technology—remain centered on<br />

the collective humanity of patient and physician, which in all<br />

its forms is our common bond.<br />

JWS retired in 1998, and died in 2007 of Parkinson’s<br />

disease. He and Ted Harris were much alike. <strong>The</strong>y were extraordinary<br />

persons who led others to perform beyond expectations,<br />

and showed all those around them that exceptional<br />

effort yields uncommon rewards. <strong>The</strong>se two men were called<br />

into different professions, but each understood precisely what<br />

it meant to “take a vow.” and to “declare publicly.” It is to the<br />

betterment of humankind that each lived, and thus our own<br />

joyful duty to ensure that their song goes on.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 1


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1 Editorial<br />

<strong>The</strong> song goes on<br />

Robert Atnip, MD<br />

35<br />

42<br />

46<br />

Health policy<br />

Our health care system is not<br />

broken—it’s obsolete!<br />

Jordan J. Cohen, MD<br />

<strong>The</strong> physician at the<br />

movies<br />

Peter E. Dans, MD<br />

Wall Street: Money Never<br />

Sleeps<br />

Conviction<br />

Reviews and reflections<br />

<strong>The</strong> Checklist Manifesto: How to<br />

Get Things Right<br />

Reviewed by David A. Bennahum,<br />

MD<br />

<strong>The</strong> Jump Artist<br />

Reviewed by Jeffrey L. Ponsky,<br />

MD<br />

Henry Kaplan and the Story of<br />

Hodgkin’s Disease<br />

Reviewed by William M. Rogoway,<br />

MD<br />

<strong>The</strong> National Institutes of Health:<br />

1991–2008<br />

Reviewed by Jack Coulehan, MD<br />

51 Letters<br />

AΩA NEWS<br />

38 2010 <strong>Alpha</strong> <strong>Omega</strong><br />

<strong>Alpha</strong> Robert J. Glaser<br />

Distinguished Teacher<br />

Awards<br />

52<br />

DEPARTMENTS<br />

National and chapter news<br />

Instructions for <strong>Pharos</strong> Authors<br />

Leaders in American Medicine<br />

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ARTICLES<br />

Visionary art?<br />

Shamans, Charles Bonnet, and the cave<br />

paintings<br />

Henry N. Claman, MD<br />

�<br />

Going first<br />

Susie Morris, MD, MA<br />

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<strong>The</strong> monsters of medicine<br />

Political violence and the physician<br />

Amanda J. Redig, MD, PhD<br />

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Breaking bad news<br />

What poetry has to say about it<br />

Dean Gianakos, MD<br />

From rabbits to the<br />

League of Nations<br />

Early standardization of the insulin unit<br />

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Barry Fields, MD<br />

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On the cover<br />

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See page 4<br />

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<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> 2008 3<br />

11 Room K461<br />

Mary Krane Derr<br />

15 Musings on an Attic<br />

Tetradrach<br />

Alvin J. Cummins, MD<br />

23 Sestina on Limb-<br />

Lengthening Surgery<br />

Jenna Le<br />

27 Heartache<br />

John Allan, MD<br />

34 <strong>The</strong> Defendant<br />

H. Harvey Gass, MD<br />

36 Memento Mori<br />

Michael R. Milano, MD<br />

37<br />

40<br />

POETRY<br />

Reading a Review<br />

H. J. Van Peenen, MD<br />

Winning Poems of the<br />

2010 Write a Poem for<br />

This Photo Contest<br />

Benevolent Instructions<br />

David R. Downs, MD<br />

Commencement<br />

David F. Dozier, Jr., MD<br />

Adolescent Choices<br />

H. J. Van Peenen, MD<br />

XX Ageless<br />

Thomas Atwater<br />

INSIDE<br />

BACK<br />

COVER


Visionary art?<br />

Shamans, Charles Bonnet, and the cave paintings<br />

Henry N. Claman, MD<br />

<strong>The</strong> author (AΩA, University of Colorado, 1979) is<br />

Distinguished Professor of Medicine and Associate Director<br />

of the Medical Humanities Program at the University of<br />

Colorado, Denver. He is a member of the editorial board of<br />

<strong>The</strong> <strong>Pharos</strong>.<br />

Paleolithic art, particularly the cave paintings of<br />

Southwestern Europe, is a source of amazement still.<br />

<strong>The</strong>se images haunt many of us, not only because of<br />

their beauty and their great age, (stretching back over 30,000<br />

years), but because they are one of the few entrées we might<br />

have into the lives of our ancestors, who are among the great<br />

masters of artistic creativity, and about whom we know very<br />

little apart from this art. <strong>The</strong> study of this art continues to<br />

expand as art historians, anthropologists, archaeologists, and<br />

natural history scientists try to unravel the mystery of what<br />

the art “means” and why it was made. <strong>The</strong>re is a wide divergence<br />

in opinions on this subject, and some experts have actually<br />

warned against further attempts to discover “the meaning”<br />

of paleolithic art. However, it is hard to abandon the quest,<br />

and this contribution attempts to call attention to another<br />

possible avenue of interpretation, relying on new neurophysiological<br />

concepts.<br />

<strong>The</strong> art was produced in profusion, and consists mainly<br />

of paintings and engravings, as well as sculpture in the round<br />

and in bas-relief. <strong>The</strong> early members of our genus and species,<br />

Homo sapiens sapiens, were hunter-gatherers. <strong>The</strong>y lived in<br />

small nomadic bands of perhaps fifty to one hundred people,<br />

in a mostly egalitarian society. <strong>The</strong>y made stone tools and had<br />

fire but made neither cloth nor pottery. Half of the art is in<br />

limestone caves and half is outside, mainly in shelters. Those<br />

in the caves are better preserved and have received the most<br />

attention.<br />

What was depicted? Many of the most prominent images<br />

are of animals, mainly large ones such as horses, bisons, bovids,<br />

lions, rhinoceri, reindeer, and so forth. Rarely seen is a<br />

small animal such as a rabbit or owl. <strong>The</strong> large animals are almost<br />

always shown in profile, in big or small images, complete<br />

or fragmentary. When I was lucky enough to be in the Great<br />

Hall of the “original” Lascaux cave (now closed to the public)<br />

I felt that I was engulfed in the midst of a huge stampede. It<br />

was an overwhelming experience of power and speed. In addition<br />

to all the animal depictions, however, there are a lesser<br />

number of human figures, or parts of humans, including positive<br />

and negative hand prints and images of (mainly female)<br />

genitalia. Intact humans are rare and almost always masked.<br />

<strong>The</strong>re is a also very large number of enigmatic forms that are<br />

Man looking at prehistoric cave painting of animals.<br />

Photo by Ralph Morse//Time Life Pictures/Getty Images.<br />

4 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 5


Visionary art?<br />

Bulls, horses, deer, Lascaux Cave, France, about 17,000 years ago.<br />

© <strong>The</strong> Bridgeman Art Library/Getty Images, Inc.<br />

difficult to describe, called abstract symbols, or designs, and<br />

so forth. <strong>The</strong>se range from simple colored dots or strokes or<br />

carved shallow cupules in the stone to complex grid-like paintings<br />

or engravings. Some of these geometric designs have been<br />

termed “tectiforms” (roof-like) although there is no evidence<br />

that there were any roofs.<br />

<strong>The</strong>se abstract forms, because of their refusal to give up<br />

their secrets, have been rather neglected by historians, at least<br />

in comparison with the more flamboyant animal images, to<br />

say nothing about the carved and decorative mostly female<br />

statuettes (misnamed “Venus” figurines). <strong>The</strong>se abstract images<br />

can give us additional clues as to the production of the<br />

art in general.<br />

Deciphering the “meanings” of paleolithic art<br />

Analyzing the art is a formidable task, and the process continues,<br />

with various schema current at one time or another. 1,2<br />

Art for art’s sake—During the period when paleolithic art<br />

was known mainly from small carved and engraved bones and<br />

antlers, the genre was regarded as aesthetic and playful. This<br />

approach has been largely abandoned.<br />

Sympathetic magic—When the great cave paintings of<br />

Altamira and Lascaux were discovered, the depiction of large<br />

hunted animals, often with spears or arrows in them, led<br />

to the concept of “hunting magic” or “sympathetic magic.”<br />

According to this model, emphasized by Sir James Frazer in<br />

<strong>The</strong> Golden Bough, hunter-gatherer people made pictures of<br />

their prey to remember yesterday’s foray or to imagine and<br />

ensure the success of tomorrow’s venture. 3 This interpretation<br />

has its advocates today.<br />

In the structuralist approach, pioneered by André Leroi-<br />

Gourhan, the images were subjected to sophisticated measuring<br />

and counting techniques that led to interpretations of the<br />

arrangement of art in symbolic terms, emphasizing quantitative<br />

correspondences and dualistic contrasts, e.g., male versus<br />

female symbols, red versus black images and horses versus<br />

bison. 4 <strong>The</strong> ultimate rationale may have been to promote fertility<br />

in both human and animal worlds, which were, of course,<br />

extremely interwoven and interdependent in hunter-gatherer<br />

societies. Many find this approach arcane.<br />

6 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Emphasis currently centers on what has been called the<br />

mystico/religious interpretation, in which spiritual concepts<br />

are invoked and shamans are considered to be closely involved<br />

in art production and corresponding ritual activities. This approach<br />

is largely influenced by David Lewis-Williams and his<br />

studies of the rock art of the San People of South Africa. He<br />

applies this interpretation to paleolithic and neolithic art. 5,6<br />

R. Dale Guthrie dismisses this concept in favor of a natural<br />

history/evolutionary schema, placing the art in the larger context<br />

of environmental influences and linking artistic behavior<br />

to our evolutionary past. 2<br />

None of these approaches has unanimous scholarly approval.<br />

Indeed, experts are beginning to doubt that we will<br />

ever uncover “the meanings.” Yet the desire to do so is irresistible,<br />

and so let us turn to a particular image.<br />

<strong>The</strong> shaman of Lascaux<br />

This astonishing figure, discovered when the cave itself<br />

was opened in 1940, should have brought the idea of shamans<br />

to the fore right away. It is unique, being the only complete<br />

“<strong>The</strong> Shaman of Lascaux,” about 17,000 years ago. A bird-headed and -handed ithyphallic stick man in front of a wounded bison,<br />

pierced by spears, with entrails spilling out. <strong>The</strong> Shaman has a bird-head staff. © Charles and Josette Lenars/CORBIS.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 7


Visionary art?<br />

Abstract “designs” (with perhaps a positive handprint)—a montage of items from caves in what is now France and Northern Spain, about<br />

17,000–10,000 years ago. Illustration by Jim M’Guinness.<br />

human image in the cave. It is far from the stampede of animals<br />

I mentioned above, and is placed on the wall at the bottom<br />

of an eighteen-foot “well” or “shaft”—curiously isolated<br />

and difficult to access. Considering the general profusion of<br />

animals on the walls and even the ceilings, the shaman is solitary<br />

and secluded. This stick-figure of a man, drawn poorly in<br />

outline, has a bird’s head and bird’s hands, with a bird-headed<br />

scepter at his side. He is obviously male, with a prominent<br />

erect penis (the “ithyphallic position”)—a symbol of power.<br />

He is either upright or leaning, depending on the angle of the<br />

photograph. He is next to a well-drawn bison that is looking<br />

over its shoulder at a gaping wound in his flank with his intestines<br />

falling out. <strong>The</strong>re are two spears in his side.<br />

I agree with Joseph Campbell that he is a shaman, part<br />

human, part bird. 7 Including the bison, the ensemble must<br />

be the oldest narrative visual scene in human history. Yet it<br />

is profoundly ambiguous. What is the story? What is the shaman’s<br />

role vis-à-vis the bison?—a healer?—a hunter? Is he in a<br />

trance? Is he drugged? Why is he ithyphallic?<br />

Nevertheless, he is not the only masked magic man in the<br />

caves. <strong>The</strong>re is the masked and antlered “sorcerer” man in the<br />

Trois Freres cave, and others as well.<br />

8 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


<strong>The</strong> abstract designs—providing clues?<br />

Returning to the abstract images, it is understandable<br />

that they have received less attention<br />

than those of animals and people. <strong>The</strong>y are very<br />

numerous, but are often small and have proved<br />

opaque to interpretation. Perhaps the most attentive<br />

scholar has been S. Giedion, the Swiss<br />

historian. He believed that “symbolization is the<br />

key to all paleolithic art,” 8p79 and he points out<br />

that the “great abstract symbols which have no<br />

counterpart in the world of reality” are often<br />

“hidden away in the most inaccessible parts of the<br />

caverns.” 8p241 While the meanings of female pubic<br />

triangles and vulvas as well as penile images are<br />

easy to understand in terms of fertility and procreative<br />

symbolism, this is not true of the abstract<br />

designs. What then?<br />

Lewis-Williams thinks they are hallucinations,<br />

conjured up by shamans in trances, which<br />

provided powerful spiritual experiences of the<br />

San People’s three-tiered cosmos, and which<br />

were later displayed as rock art—petrographs and<br />

petroglyphs. 5 This is a concept worth considering.<br />

<strong>The</strong> hallucination approach<br />

This is a complicated subject indeed. <strong>The</strong><br />

very long list of conditions associated with visual<br />

hallucinations includes ocular disorders, CNS<br />

disorders, toxic disturbances, psychiatric illnesses,<br />

and “normal” persons. 9 In the context of<br />

images hidden in large, dark caves, it is of interest<br />

that a number of the hallucinogenic scenarios<br />

in “normal” persons involve forms of sensory<br />

deprivations. <strong>The</strong>se include dreams, hypnagogic<br />

and hypnotic states, sleep deprivation, and simply<br />

blindfolding. To this list should now be added a<br />

relatively new syndrome.<br />

<strong>The</strong> Charles Bonnet Syndrome<br />

This condition has a curious history. 10 Bonnet,<br />

born in 1720, was a Swiss/French naturalist and<br />

philosopher. (He deserves more recognition for<br />

his experiments in wood lice, establishing the phenomenon<br />

of parthenogenesis.) In 1760 he wrote a book in which he<br />

described how his eighty-seven-year-old grandfather lost his<br />

vision to cataracts and developed hallucinations “of men, of<br />

women, of birds, of carriages, of buildings.” Interestingly, the<br />

same later happened to Bonnet himself.<br />

<strong>The</strong> situation lay fallow until 1967 when George de Morsier<br />

proposed the term Charles Bonnet Syndrome (CBS) to describe<br />

the presence of recurrent visual hallucinations generally<br />

in persons with impaired vision but without clouded<br />

sensoria. Such persons are often elderly. Since then, the<br />

syndrome has been increasingly recognized and studied. 11 It<br />

is present in perhaps ten percent of the elderly with impaired<br />

vision.<br />

<strong>The</strong> hallucinations experienced are varied and often complex,<br />

in contrast to “unformed” hallucinations such as spots<br />

and flashes of light, which are termed “phosgenes.” <strong>The</strong>y include<br />

animals, humans, geometric figures, and designs, similar<br />

to what is seen in the caves. <strong>The</strong>y are in color or black and<br />

white, and are often brilliant and clear, contrasting with the<br />

poor “regular” vision of the subjects. <strong>The</strong>y frequently fade or<br />

disappear as sight deteriorates further. <strong>The</strong> commonest cause<br />

of CBS in our society is age-related macular degeneration,<br />

but it has been reported in the young and also in association<br />

with pathological changes from the eye to the visual cortex.<br />

To diagnose CBS, there should be no evidence of delirium,<br />

dementia, psychosis, or intoxication. <strong>The</strong> visions are not felt<br />

to originate in the eye itself. 11<br />

It is well-known that hallucinations with a normal sensorium<br />

may be provoked or aggravated by a number of factors<br />

including sensory deprivation, the hypnagogic state, physical<br />

or auditory stimuli, extreme pain, etc. 9 <strong>The</strong> same is true of<br />

CBS.<br />

<strong>The</strong> pathophysiology of CBS—the release<br />

phenomenon<br />

<strong>The</strong> idea that hallucinations may be caused by “irritative”<br />

foci in the brain derives by analogy from John Hughlings<br />

Jackson’s analysis of focal epilepsy. This explanation for hallucinations<br />

has generally given way more recently to the<br />

work of David Cogan 12 (who also refers to Louis J. West 13 )<br />

that suggests that hallucinations of various types are instead<br />

“release phenomena.” Interestingly, this concept also derives<br />

from Hughlings Jackson, who developed the general concept<br />

that higher functional layers of the CNS normally inhibit<br />

lower layers. When, however, the higher layers are themselves<br />

impaired, normally suppressed activities of the lower layers<br />

are released. (Consider the spasticity of the pithed frog or<br />

alcohol-induced misbehavior.) In the visual system, normal afferent<br />

stimuli dampen or block the spontaneous “endovision”<br />

activities. But when, in some people, blindness “deafferents”<br />

the visual pathways, the spontaneous endovisual activities take<br />

over, leading to hallucinations. In fact, fMRI studies support<br />

this concept. 14<br />

Hallucination manifestations<br />

Many studies of hallucination point out similarities in the<br />

images that are seemingly independent of the cause and the<br />

culture involved. Heinrich Klüver, with an extensive experience<br />

primarily associated with mescal studies, wrote of three<br />

stages of evolving hallucinations 15 :<br />

Type I—“Form constants,” namely geometric abstract designs<br />

described as gratings, lattices, fretwork; also tunnels,<br />

alleys, vessels; and spirals.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 9


Visionary art?<br />

Type II—Familiar objects such as people, faces, animals,<br />

landscapes.<br />

Type III—Fabulous landscapes and monstrous forms.<br />

Hallucinations in paleolithic art?<br />

<strong>The</strong> above outline of selected aspects of paleolithic imagery<br />

suggests that the abstract designs may not in fact be symbols.<br />

In fact, it was never clear what they might have symbolized.<br />

Instead they may be graphic representations of visual hallucinations—the<br />

“form constants” of Klüver’s Stage I.<br />

<strong>The</strong>re are a number of circumstances that support this<br />

hypothesis, circumstances that reinforce each other:<br />

1. Many of the paintings and engravings are made in very<br />

deep caves, where the darkness (and difficulty of access) is<br />

daunting. <strong>The</strong>ir very locations, even if dimly illuminated by<br />

the uncertain flickerings of oil lamps and flambeaux, would<br />

have been situations of considerable sensory deprivation.<br />

2. Any degree of partial visual impairment—from disease,<br />

CBS, trauma, etc.—would only heighten the deprivation.<br />

3. <strong>The</strong> possible (if not probable) use of psychedelic substances<br />

in trances or ceremonies would further the tendency<br />

to hallucinate. (What indeed was going on with the shaman<br />

of Lascaux?)<br />

4. <strong>The</strong> role of dreaming in gaining access to mental imagery<br />

should not be discounted.<br />

Conclusion<br />

Does the “hallucination approach” to the abstract designs<br />

give us any insight into the most intriguing problem of<br />

paleolithic art—the “meaning(s)” of the animal portrayals?<br />

Certainly, in a hunt-oriented culture dependent on animal<br />

protein for sustenance and perhaps also on animal skins for<br />

protection and disguise, it is not surprising to see those images.<br />

But it is not so simple. We are not seeing the mere paleolithic<br />

dinner menu, as many of the animal species portrayed<br />

were too dangerous to hunt and were, to judge from bony<br />

remains, not eaten. Nonetheless, the images of these animals<br />

demonstrate power, when one considers their numbers, their<br />

sizes, their detailed and imaginative depictions, their often<br />

secluded locations, and their artistic skill. <strong>The</strong> purposes were<br />

probably multiple, including messages such as “come here<br />

and nourish us” as well as “stay away—you’re dangerous” (the<br />

apotropaic or “warding off evil” strategy).<br />

<strong>The</strong> shaman of Lascaux confronting the wounded bison<br />

(risking being wounded himself in the process) would seem<br />

to provide a conceptual and possibly material link between<br />

the human/animal world and the realm of the spirits. It would<br />

be he who, via his trances (however induced), experienced<br />

that spiritual world and then “returned” to inspire the artists,<br />

perhaps including himself. In this context, these extraordinary<br />

portraits would reflect not only actual animals but thoughts,<br />

wishes, memories, or dreams or Type II Klüver hallucinations<br />

of them as well.<br />

E. H. Gombrich, the outstanding art historian, remarked<br />

that “the further back we go in history . . . the less sharp is<br />

the distinction between images and real things; in primitive<br />

societies, the thing and its image were simply two different . . .<br />

manifestations of the same energy or spirit.” 16p155<br />

Perhaps these artists perceived no differences at all!<br />

References<br />

1. Bahn PG, Vertut J. Journey Through the Ice Age. Berkeley<br />

(CA): University of California Press; 1997.<br />

2. Guthrie RD. <strong>The</strong> Nature of Paleolithic Art. Chicago: University<br />

of Chicago Press; 2005.<br />

3. Frazer JG. <strong>The</strong> Golden Bough: <strong>The</strong> Roots of Religion and<br />

Folklore. New York: Avenel Books; 1981.<br />

4. Leroi-Gourhan A. <strong>The</strong> Dawn of European Art: An Introduction<br />

to Palaeolithic Cave Painting. Cambridge: Cambridge University<br />

Press; 1982.<br />

5. Lewis-Williams D. <strong>The</strong> Mind in the Cave: Consciousness and<br />

the Origins of Art. London: Thames and Hudson; 2002.<br />

6. Clottes J, Lewis-Williams D. <strong>The</strong> Shamans of Prehistory:<br />

Trance and Magic in the Painted Caves. New York: Harry N.<br />

Abrams; 1998.<br />

7. Campbell J. <strong>The</strong> Masks of God: Primitive Mythology. New<br />

York: Penguin Books; 1976: 300–302.<br />

8. Giedion S. <strong>The</strong> Eternal Present: A Contribution on Constancy<br />

and Change. New York: Bollingen Foundation; 1962.<br />

9. Cummings JL, Mega MS. Chapter 13: Hallucinations. In:<br />

Cummings JL, Mega MS. Neuropsychiatry and Behavioral Neuroscience.<br />

Oxford: Oxford University Press; 2003: 187–99.<br />

10. Hedges TR Jr. Charles Bonnet, his life, and his syndrome.<br />

Surv Ophthalmol 2007; 52: 111–14.<br />

11. Menon GJ, Rahman I, Menon SJ, et al. Complex visual hallucinations<br />

in the visually impaired: <strong>The</strong> Charles Bonnet Syndrome.<br />

Surv Ophthalmol 2003; 48: 58–72.<br />

12. Cogan DG. Visual hallucinations as release phenomena. Albrecht<br />

v Graefes Arch klin exp Ophthal 1973; 188: 139–50.<br />

13. West LJ. Chapter 9: A Clinical and <strong>The</strong>oretical Overview of<br />

Hallucinatory Phenomena. In: Siegel RK, West LJ, editors. Hallucinations:<br />

Behavior, Experience, and <strong>The</strong>ory. New York: John Wiley &<br />

Sons; 1975: 287–311.<br />

14. ffytche DH, Howard RJ, Brammer MJ, et al. <strong>The</strong> anatomy<br />

of conscious vision: an fMRI study of visual hallucinations. Nature<br />

Neurosci 1988; 1: 738–42.<br />

15. Klüver H. Mescal and Mechanisms of Hallucinations. Chicago:<br />

University of Chicago Press; 1966.<br />

16. Sontag S. On Photography. New York: Farrar, Straus and<br />

Giroux; 1977.<br />

<strong>The</strong> author’s address is:<br />

Allergy/Immunology B164 RC2<br />

12700 E. 19th Avenue, Room 10100<br />

Aurora, Colorado 80045<br />

E-mail: henry.claman@ucdenver.edu<br />

10 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


R O O M<br />

For Adrian Felix Carroll<br />

Tiny blue open-backed gown<br />

that never quite ties back up.<br />

Tiny blood pressure cuff,<br />

thermometer cuff.<br />

Tiny vital signs.<br />

Tiny primary color-coded IVs,<br />

tiny calibrated pumpings<br />

of opiate, anxiolytic, total<br />

parenteral nutrition with adjusted<br />

lipids to avert liver failure.<br />

Tiny blood transfusion.<br />

Tiny ostomy bag.<br />

Tiny liquid rolling crescents<br />

of bluegreen wake-eye. Tiny<br />

flickering visits with.<br />

Tiny answers<br />

from hall-snagged docs.<br />

So what is there here<br />

to miniaturize away<br />

this innards-clawing, hemorrhagic<br />

fever of grief?<br />

Mary Krane Derr<br />

Mary Krane Derr is a poet, writer, musician,<br />

chronic disease patient, and fourth-generation<br />

South Side Chicagoan. Her address is: 6105 South<br />

Woodlawn #3S. Chicago, Illinois 60637. E-mail:<br />

marykderr@aol.com.<br />

Illustration by Jim M’Guinness<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 11


���������<br />

Susie Morris, MD, MA<br />

<strong>The</strong> author is a resident in Psychiatry<br />

at the University of Southern<br />

California. This essay won honorable<br />

mention in the 2010 <strong>Alpha</strong> <strong>Omega</strong><br />

<strong>Alpha</strong> Helen H. Glaser Student Essay<br />

Competition.<br />

She has it so easy.<br />

I guess this shouldn’t be the<br />

first thing that comes to mind<br />

when I look at her. It’s about 12:30 in<br />

the afternoon. She is supine, dare I say<br />

resting? I feel uncomfortable calling<br />

her comfortable because I wonder if<br />

she’s already dead. I wonder if she died<br />

yesterday after she stopped speaking to<br />

us. I peel her eyelids back, and they are<br />

dilated. But she is propped here nonetheless,<br />

her heart still beating faintly<br />

through layers of fat under my stethoscope.<br />

At this point, it’s a stupid ritual.<br />

Her brother and niece are here looking<br />

on.<br />

“Kat went home for a shower,” her<br />

brother tells me. “Dr. Li talked her into<br />

it this morning. He needed to remind<br />

her it was okay to take care of herself.”<br />

Kat is Jenn’s partner. I can’t tell you<br />

how many lesbians I’ve known who<br />

went by Kat or Jenn. As her brother<br />

says her name, I wonder if she was a<br />

Katie or Kathy growing up and then<br />

switched to Kat later in life because it<br />

meshed better with her butch identity.<br />

I met the two of them four days ago.<br />

I found them, Jenn and Kat, sitting in<br />

this hospital room with a broad view<br />

of the city. Kat was perched anxiously<br />

on the fold-out couch, and Jenn was<br />

reclined confidently in the armchair<br />

next to her hospital bed, fully clothed in<br />

a short-sleeved button down and denim<br />

shorts. Both women had short unmistakably<br />

gay hair—the same haircut I<br />

once attempted during college when I<br />

was trying on my own identity. I was<br />

immediately drawn to them because<br />

something about them reminded me<br />

of home.<br />

Jenn told me that she’d been having<br />

hip pain, deep in her left side. She<br />

pointed to the region, and Kat watched<br />

her with cat-like eyes as if to make sure<br />

she described it in its full detail. Jenn<br />

starts a sentence with a slow, casual<br />

voice, one of those just-because-I-can<br />

smiles on her face. Kat finishes those<br />

sentences sharply with full medical detail,<br />

leaning forward into my face closer<br />

and closer each time.<br />

“I guess it started on like Friday, I<br />

think,” Jenn says, kind of looking out at<br />

the cityscape through the window.<br />

“Yes, it was Friday,” Kat states with<br />

some urgency.<br />

No fevers, no bowel symptoms, urinary<br />

symptoms, nothing. Just the pain.<br />

“And Kat says she saw a lymph node<br />

or something. That right, hon?”<br />

“Yes, she has a swollen inguinal<br />

lymph node. I first felt it on Friday, too,<br />

when she was in the shower.” Kat’s face<br />

is wrinkled now, with worry. Her eyes<br />

are dry but red and irritated. She uses<br />

the word “inguinal” to warn me that she<br />

too is medical.<br />

Jenn and Kat are nurses, home health<br />

nurses. This is actually how they met.<br />

“She was the leader of our team,”<br />

Kat tells me later with fresh pride as if<br />

it were yesterday, when in reality, Jenn’s<br />

illness has prevented her from working<br />

for months now.<br />

I think about this: the two of them<br />

making house visits together, surrounded<br />

by the death and sickness<br />

that provided the backdrop for their<br />

romance. Kat was smiling during the<br />

retelling, and her face was transparent<br />

with the old thrill of seducing her<br />

former boss. This was twelve years ago<br />

now. Four years ago, Jenn became suspiciously<br />

swollen. She was diagnosed with<br />

ovarian cancer. <strong>The</strong> intervening years<br />

are notable now for one large reductive<br />

surgery, the loss of Jenn’s uterus,<br />

ovaries, and omentum, and half a dozen<br />

chemotherapy trials. I pulled up her latest<br />

PET scan, and stable mets glowed<br />

back at me, a reminder that the chemotherapy<br />

had only delayed the inevitable<br />

for now. Luckily, she had remained<br />

physically quite strong and was looking<br />

forward to starting a new chemo regimen<br />

next week.<br />

It was Kat who kept her so fit. She<br />

administered meticulous, gentle care<br />

round the clock, but the past six months<br />

had proven increasingly difficult as Jenn<br />

suffered from intractable abdominal<br />

pain and several admissions for small<br />

bowel obstructions. Kat knew the landscape<br />

of Jenn’s body better than Jenn<br />

ever had. This is what one would expect<br />

of lovers of twelve years, except Kat’s<br />

knowledge was borne of something different.<br />

Kat’s eyes now combed the body<br />

of her life partner seeking suspicious<br />

changes, marks that portended the future,<br />

rather than pleasured in the right<br />

12 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


now. <strong>The</strong> numbers in her last CBC, her<br />

last bowel movement, its consistency,<br />

the color and volume of her urine. It was<br />

terror that prompted her daily searches<br />

and created, for them, a new connection<br />

between their bodies, a novel sort<br />

of lovemaking.<br />

It reminded me of years earlier when<br />

I totaled my car. My partner’s mother<br />

had sent us on our way that rainy morning.<br />

We called her later that day from<br />

the interstate, my car in pieces, to tell<br />

her what happened. She told me later<br />

that every time one of her girls left<br />

home, she always imagined the worst,<br />

thinking that if she thought of it first,<br />

it would never happen. That day, it<br />

seemed her pre-emptive imaginings<br />

had betrayed her. I wonder if Kat’s<br />

relentless surveying and bargaining<br />

came out of the same hope.<br />

“It was here-ish,” Kat said, her<br />

fingers plunged into Jenn’s groin,<br />

her gray pubic hair exposed while<br />

my resident and I stood by. Jenn<br />

was half listening, half aware of the<br />

low buzz of All My Children coming<br />

from the flat screen. “For some reason,<br />

I guess I can’t feel it now,” she said, bewildered<br />

and frustrated.<br />

“I never felt anything,” Jenn laughed.<br />

Kat scowled at the floor, seemingly pondering<br />

how her own fingers had somehow<br />

deceived her.<br />

I couldn’t feel anything either.<br />

Neither could my resident. At Kat’s urging<br />

though, in addition to increasing<br />

Jenn’s pain meds, we agreed to get some<br />

lab work and an abdominal CT.<br />

Kat and Jenn had spent the past<br />

two years or so preparing for the final<br />

moments. On the palliative service, I’d<br />

found this was actually kind of rare.<br />

Most people would delay and delay,<br />

throwing radioactivity and chemicals<br />

at tumors that laughed at their efforts,<br />

growing into organs and bone, hiding<br />

from x-rays and stealing moms away<br />

from babies, babies away from moms,<br />

lovers from lovers. Kat and Jenn, in addition<br />

to pursuing aggressive curative<br />

therapies, sought comfort in psychotherapy<br />

where they spoke freely about<br />

what was to come, what Jenn wanted it<br />

to look like, when and under what circumstances<br />

she wanted to stop.<br />

“Well, I’ve had four years since I was<br />

diagnosed.” Jenn is very frank with her<br />

words. “You know, I’d love four more.<br />

Shit, I’d like forty more, but we’re prepared<br />

either way.” I believed that Jenn<br />

was. Kat was another story. Kat’s movements<br />

were like Jenn’s words, decisive<br />

and exact. Wiping sweat from Jenn’s<br />

forehead, combing her hair from her<br />

face, positioning her arms about her<br />

body. However, sometimes I caught her,<br />

in between stoic statements, staring<br />

down at the floor like someone does<br />

whose eyes just flooded, waiting for the<br />

water to resorb, and then looking back<br />

up into the conversation.<br />

We really thought her pain sounded<br />

like a pulled muscle or something.<br />

Something really mild. She was pooping<br />

and peeing and without other systemic<br />

signs of something going wrong.<br />

Perhaps her pain was just related to<br />

her being almost sixty and overweight.<br />

Perhaps it had nothing to do with her<br />

cancer at all. It appeared to be a false<br />

alarm, and I figured we’d have her back<br />

home in no time. As I talked out my differential<br />

with the two of them, Kat nodded<br />

with some degree of relief, albeit<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 13


Going first<br />

About the author<br />

I was born and raised<br />

in rural Utah. I attended<br />

Smith College and graduated<br />

with a degree in<br />

philosophy in 2004. I<br />

am a recent graduate<br />

of Northwestern<br />

University Feinberg School of<br />

Medicine where I earned my<br />

MD and my Masters in Medical<br />

Humanities and Bioethics. I am<br />

starting my residency in psychiatry<br />

this year at the University of<br />

Southern California. I hope to pursue<br />

a career in geriatric psychiatry.<br />

guarded. She accepted my explanation<br />

but called the family anyway.<br />

Jenn reminded me again: “Kat is my<br />

power of attorney.”<br />

“Yes, of course.” I was relieved they’d<br />

done the paperwork, aware of all the<br />

hospital horror stories that had befallen<br />

other gay couples, thinking also that<br />

it was premature to be worrying who<br />

would make decisions for her if she<br />

couldn’t do so herself. She looked just as<br />

healthy as I did.<br />

Radiology paged my attending the<br />

following afternoon. I pulled up Jenn’s<br />

CT. She had an abscess in her back muscle,<br />

on the left, just where her pain had<br />

originated. It was large enough for a med<br />

student to see it, meaning it was pretty<br />

damn big. It was a pillowed pocket of<br />

air and fluid, indicating either active<br />

bacteria or a fistula between her bowel<br />

and back or both. Either way, the recommendation<br />

was to stick a drain in it. I<br />

remember being surprised although not<br />

alarmed. We’d stick a central line in her<br />

neck and send her home with IV antibiotics<br />

and a drain coming out of her side.<br />

She continued to appear very well—<br />

moving around her room, her pain<br />

under better control. I was shocked<br />

to see an elevated white count on her<br />

CBC. She didn’t look sick! I scheduled<br />

her with interventional radiology the<br />

following afternoon. <strong>The</strong> drain was<br />

placed without incident. That evening,<br />

I dropped by her room to say hello.<br />

She and Kat had visitors: Jenn’s sisters,<br />

brother, and niece. Jenn seemed jovial.<br />

Kat appeared more at ease than before.<br />

She even smiled when I told her goodnight.<br />

“See you tomorrow,” Jenn said. Her<br />

sister hugged me. “See you tomorrow,<br />

girlfriend,” she said.<br />

Before heading to her room the next<br />

morning, I pulled her vitals up on the<br />

computer. Her heart rate was up, all<br />

night, into the hundreds. Her most recent<br />

blood pressure read 90/60: alarmingly<br />

low. Topped with a fever of 102<br />

degrees. All signs pointed to sepsis. I<br />

could feel my own heart bump around<br />

in my chest. I could feel my fingertips<br />

and groin get numb with the anxiety of<br />

heavy failure. How could I have not seen<br />

this coming?<br />

I waited for my attending before I<br />

went to the room. I was afraid of the<br />

picture that the vitals had painted for<br />

me, and I knew that if I actually looked<br />

at her, that would only make it real. I<br />

wasn’t ready to hit that on my own.<br />

“It appears that Jenn is septic,” my<br />

attending explained to the family. <strong>The</strong>y<br />

didn’t know sepsis from a septic tank,<br />

none of them medical. But the connection<br />

between the two seemingly related<br />

entities conjured a fitting image of severity.<br />

I could see that. Kat knew best<br />

though, herself a nurse. <strong>The</strong> word softened<br />

her voice and cut deep lines in her<br />

weary face. She looked ruddy, almost<br />

hungover with sadness this morning.<br />

She knew it all along. She had been<br />

guarded, accepting our explanations and<br />

speculations throughout the admission.<br />

Carefully optimistic, but knew to call<br />

the family anyway.<br />

Looking at Jenn: she knew too. It<br />

wasn’t the pain that brought her in, I<br />

decided, looking back at it from where<br />

I was in time now. <strong>The</strong> pain had been a<br />

sign, and she knew.<br />

We asked the regular questions.<br />

“What’s your understanding of what’s<br />

going on, Jenn?” That’s my attending’s<br />

gentle voice, priming them for the<br />

events looming on the horizon.<br />

“Well, it looks like I may die.” Her<br />

frankness was killing me. I had to swallow<br />

hard and look away from her. Kat<br />

took her hand and moved to sit on her<br />

bed. She couldn’t get close enough to<br />

her. I remember feeling that way as a<br />

child, small spooning my mom in my<br />

parent’s bed at night, thinking that if I<br />

could just get closer and closer, I would<br />

be invincible. This is how Kat looked<br />

at Jenn now—like if she could just get<br />

close enough, maybe she could keep her,<br />

get away from the bad-news voices, and<br />

be invincible.<br />

Jenn was weak, intermittently trailing<br />

off, but lucid when she needed to<br />

be. In between cracking jokes about<br />

the doom in the room, she made her<br />

intentions very clear, careful always to<br />

speak in the first person, plural. Now,<br />

she was speaking for Kat, too. Jenn may<br />

have been dying, but it seemed Kat was<br />

surrendering. She asked us to stop the<br />

antibiotics.<br />

“I’m at peace, you know,” she huffed,<br />

showing her exhaustion. “Everyone is<br />

here. Kat’s here.”<br />

“She keeps twitching,” Kat said,<br />

watching Jenn’s legs worm around under<br />

the sheets.<br />

“Oh, that doesn’t bother me,” Jenn<br />

said.<br />

We ignored Jenn and started something<br />

to stop the twitching. Our focus<br />

had shifted from treating Jenn to protecting<br />

Kat. If Kat didn’t want to see<br />

twitching, then we would make it so.<br />

That was the one thing we could do for<br />

her. It made me feel a little more useful<br />

in my attempts to make up for the colossal<br />

failure I’d suffered against the natural<br />

forces that were claiming Jenn.<br />

Jenn didn’t really speak again after<br />

that. She fell into a kind of trance,<br />

sometimes restless. At those times, we<br />

gave her morphine, and she was quieted<br />

again. Her breathing was rough.<br />

We patched her with scopolamine and<br />

fentanyl.<br />

14 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Kat claimed that she and the family<br />

were working shifts. This was a lie. <strong>The</strong><br />

family wandered in and out through<br />

the day. Kat went nowhere, sitting on<br />

the bed, feeling Jenn’s skin, placing ice<br />

packs, requesting acetaminophen suppositories<br />

to bring down Jenn’s fever.<br />

My resident told her this morning<br />

to go home for a while, get a shower, a<br />

change of clothes. Eat something. “Don’t<br />

feel guilty,” he’d told her. And she left.<br />

During her absence, I thought I’d<br />

take a break, too. Jenn was clinging to<br />

the status quo. I thought she’d make it<br />

through the weekend. I went to the cafeteria<br />

to get a soda. My pager went off<br />

about that time.<br />

Jenn’s brother and niece were sitting<br />

next to the bed. <strong>The</strong> television was off,<br />

the sun beat down on the window. It<br />

made me think it was warm outside<br />

when really, it was just a cool 60 degrees<br />

with some incidental sunlight here and<br />

there. Jenn’s face was grey, her hands<br />

still warm. I placed my stethoscope<br />

over her chest and watched the clock.<br />

<strong>The</strong> silence in her chest was eerie. <strong>The</strong><br />

Owl, symbol of Athens, reverse of<br />

a silver tetradrachm from Athens. © Corbis.<br />

sixty seconds were long and made me<br />

very aware of the pain in my back from<br />

bending over. Kat hadn’t made it back<br />

yet, but she had just called. It was one<br />

o’clock.<br />

“Is she gone?” She asked Jenn’s niece<br />

without being prompted.<br />

“She’s in heaven now,” her niece<br />

whispered as we performed our rituals.<br />

Maybe it brought her some comfort to<br />

say that.<br />

I Googled her name until her obituary<br />

was finally posted. It took the family<br />

over a week to put her in the ground.<br />

Until that time, I knew that Kat must<br />

have been surrounded by Jenn’s family<br />

coming in and out, strangers sending<br />

things like flowers and meat trays. I<br />

decided I would give her a call a couple<br />

days after the funeral. I know from<br />

my own experience that that’s when<br />

the mourning will start—when the<br />

crowds quiet down, and Kat is left to<br />

pick through Jenn’s closet, sleep in the<br />

sheets that smell like her, throw out<br />

the pill bottles that litter her cabinets,<br />

dispose of the relics that documented<br />

the presence of her and the life they’d<br />

built together. She’d be stuck wondering<br />

if she should dispose of everything that<br />

made the longing burn fresh or worry<br />

about whether it would make her forget<br />

something sacred about them. An old<br />

shirt, a matchbook, a used pencil, a half<br />

eaten sandwich. She’d want to reach out<br />

to someone to help her decide what to<br />

keep and realize that her habit for years<br />

now was to reach for Jenn.<br />

“I just wanted you to know that your<br />

relationship is really inspiring.” This was<br />

a couple hours before Jenn’s death when<br />

I found Kat in the room by herself. She<br />

cried. I think it was something that had<br />

built up for a while, and now she just<br />

couldn’t control it.<br />

“Twelve years is just not enough,” she<br />

said, sniffing and shaking her sore, red<br />

face, “but, you know, fifty wouldn’t have<br />

been enough.”<br />

<strong>The</strong> author’s address is:<br />

4249 West Sarah Street<br />

Burbank, California 91505<br />

E-mail: susielisa@gmail.com<br />

Musings on an Attic Tetradrachm<br />

What hands are these that stamped wide-eyed<br />

Owls on rounds of Laurian silver,<br />

And whose knives are those who carved<br />

Humanity on blocks of solid stone?<br />

What artist’s brush has painted antic<br />

Nymphs on urns of reddened clay,<br />

And whose minds are they who plumbed<br />

So deep within the human soul?<br />

Whose book is this which tells such tales of<br />

Bloody death on ancient Trojan shores,<br />

What princely youth has led his men<br />

To trample vast miles of Asian soil?<br />

And which men with their lines and angles<br />

First measured the circumference of the Earth?<br />

Now seek ye out the Olympian gods,<br />

And as the Delphic Sybil nods,<br />

Athena’s owl will tell you Who<br />

Alvin J. Cummins, MD<br />

Dr. Cummins (AΩA, Johns Hopkins University, 1944) is retired as professor of Medicine at the<br />

University of Tennesseee Center for the Health Sciences in Memphis. His address is: 13114 Brooks<br />

Landing Place, Carmel, Indiana 46033. E-mail: nero6@aol.com.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 15


��������<br />

Victim testifies at the Nuremberg Trials. <strong>The</strong> Doctors Trial<br />

considered the fate of twenty-three German physicians who<br />

either participated in the Nazi program to euthanize persons<br />

or who conducted experiments on concentration camp prisoners<br />

without their consent. Sixteen of the doctors charged<br />

were found guilty. Seven were executed.<br />

16 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong><br />

© dpa/dpa/Corbis


����<br />

Political violence and the physician<br />

Amanda J. Redig, MD, PhD<br />

<strong>The</strong> author (AΩA, Northwestern University, 2010) is a<br />

resident in the Department of Medicine at Brigham and<br />

Women’s Hospital in Boston. This essay won second prize<br />

in the 2010 Helen H. Glaser Student Essay Competition.<br />

Human health in the early days of a new millennium<br />

stands at the crossroads of a paradox: thanks to a vast<br />

increase in knowledge and technology, we are more<br />

effective than ever before in both the saving and the taking of<br />

lives. Indeed, the twentieth century is characterized by two<br />

incongruous realities. On the one hand, we have the hope and<br />

optimism generated by groundbreaking strides against the suffering<br />

caused by disease. Yet coupled to such progress is the<br />

dark legacy of genocide, war, and political violence on a scale<br />

previously unimaginable. What makes reconciling these two<br />

competing visions so difficult for the medical profession is the<br />

fact that physicians have been instrumental in advancing not<br />

only the achievements but also the atrocities.<br />

Decades after their deaths, physicians such as Jonas Salk<br />

or Alexander Fleming remain household names because of<br />

the effect their work has had on the advancement of medicine’s<br />

ability to heal. In contrast, there are also physicians<br />

whose names have become synonymous with the very worst<br />

of humanity, such as the “Angel of Death,” Dr. Josef Mengele.<br />

Fortunately, there are far more famous than infamous physicians,<br />

but no matter how much the medical profession may<br />

wish to think otherwise, the physician who chooses to embrace<br />

death over life is not an anomaly.<br />

<strong>The</strong> list of physicians who have participated in and furthered<br />

political violence is extensive. Nazi physicians directed<br />

the mass murder of the weak, the ill, and the disabled in 1930s<br />

Germany, as well as the horrific medical experiments of Nazi<br />

World War II concentration camps. Japan’s World War II<br />

Project 731, led by Dr. Shiro<br />

Ishii, killed thousands of POWs<br />

and Chinese and Soviet citizens<br />

in experiments on germ warfare<br />

and vivisection. Among other<br />

historic firsts, including leadership<br />

of the first organization<br />

to use hijacked airliners as a<br />

political tool, Palestinian pediatrician<br />

George Habash was also<br />

responsible for orchestrating a<br />

rocket attack on a bus full of<br />

children in which nine passen-<br />

Major Nidal Hasan<br />

HO/Reuters/Corbis<br />

gers died. Out of the violence that turned neighbor against<br />

neighbor in the former Yugoslavia, psychiatrist Radovan<br />

Karadzic is currently standing trial in the Hague for his role<br />

in the massacre of Bosnian Muslims at Srebenica and the<br />

Siege of Sarajevo. Al-Qaeda counts numerous physicians as<br />

operatives, from number two Ayman al-Zawahiri to the individuals<br />

responsible for the failed suicide bombing at Glasgow<br />

International Airport in 2007. Most recently, Fort Hood<br />

psychiatrist Major Nidal Hasan was responsible for the worst<br />

attack of terrorism on a domestic U.S. military installation in<br />

American history.<br />

Clearly, incongruity aside, physicians are not exempt from<br />

participation in the most chilling of crimes against humanity.<br />

Despite the repugnance with which most physicians view<br />

such actions on the part of their colleagues, the fact remains<br />

that politically-motivated violence perpetrated by physicians<br />

happens far too often, across all lines of politics, religion,<br />

and ethnicity. <strong>The</strong> questions to be asked are thus far more<br />

complex than whether or not a profession built on the best of<br />

intentions can exist side by side with great evil. Instead, the<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 17


<strong>The</strong> monsters of medicine<br />

medical profession must face far more nuanced questions that<br />

are much more difficult to answer. Why do some physicians<br />

act as if some lives have no value? What do their actions mean<br />

for those choosing instead to live by primum non nocere? It<br />

is too simplistic to dismiss the Mengeles and al-Zawahiris<br />

among us as either terrorists or sociopaths. <strong>The</strong> medical profession<br />

needs to go through the potentially painful process<br />

of looking inward to recognize both its unique strengths and<br />

weaknesses. After all, we remember the names of medicine’s<br />

most infamous members not because of their heinous deeds<br />

but rather because such actions were carried out by doctors.<br />

Consequently, we must look more closely at the roots of terrorism<br />

and state-led violence to understand both the physicians<br />

who embrace them, as well as those who do not.*<br />

Internal pressure: surely they must be mad<br />

<strong>The</strong> first explanation often used to make sense of physician<br />

violence is mental illness. <strong>The</strong> gulf that divides what a physician<br />

is supposed to do and what some physicians have done is<br />

so vast that it is not surprising we question the sanity of those<br />

we cannot understand. <strong>The</strong> sociopathy defense provides society—and<br />

especially the medical community—with a mental<br />

escape from the possibility that a sane individual, someone<br />

who could be any of us, would willingly engage in such horrors.<br />

At a superficial level, this initial impression seems accurate<br />

as a way of explaining aspects of both barbarism that<br />

defies words and actions that are so contradictory they cannot<br />

be reconciled. <strong>The</strong> Holocaust and the campaign in the Pacific<br />

are among the most extensively analyzed and referenced topics<br />

in the historical literature,<br />

yet the details of the medical<br />

torture that took thousands of<br />

lives still remain in the shadows.<br />

<strong>The</strong> thought of physicians<br />

removing organs or limbs from<br />

live patients without anesthesia,<br />

spinning people in centrifuges<br />

until they died, or using prisoners<br />

tied to posts to test the efficacy<br />

of flame-throwing devices<br />

stand apart as too horrific to<br />

contemplate. And what could be<br />

more contradictory than an individual<br />

who chooses a career as a<br />

physician and then participates<br />

Dr. Josef Mengele<br />

© Bettmann/CORBIS<br />

in political violence? Several of<br />

the physicians implicated in the<br />

* In this paper “terrorism” refers to Paul Wilkinson’s definition of<br />

“violence or the threat of violence,” here used primarily in reference<br />

to non-state actors. 1 “State-led violence” is used for similar actions,<br />

specifically war crimes and genocide, orchestrated by state actors.<br />

<strong>The</strong> word “violence” is used exclusively to refer to actions that have<br />

an underlying political nature, regardless of the organizational level<br />

at which such goals are pursued.<br />

Glasgow International Airport suicide<br />

bombing plot were not only<br />

practicing medicine at the time<br />

but were also living among the<br />

very people they were attempting<br />

to destroy. <strong>The</strong> duality of treating<br />

one’s neighbors by day and plotting<br />

to blow them up at night makes no<br />

sense. Even though Major Nidal<br />

Hasan’s trial has not yet begun, it<br />

is assumed that he will use an insanity<br />

defense because his actions<br />

are so at odds with his professional<br />

career. <strong>The</strong> DSM-IV definition of<br />

antisocial personality disorder—<br />

the preferred way of referencing<br />

the sociopath of common usage—<br />

Dr. Ayman al-Zawahiri<br />

AFP/Getty Images<br />

includes at its core a lack of regard for the rights of others. 2<br />

In this sense, at least, the actions of such infamous physicians<br />

seem to fit.<br />

Yet, a closer examination of the actions of these physicians<br />

makes it clear that mental illness does not explain their atrocities.<br />

<strong>The</strong> DSM definition of antisocial personality disorder<br />

is far more complex than the superficial understanding of a<br />

person who does the unthinkable; it also includes several essential<br />

criteria, starting with a pervasive pattern of disregard<br />

for and violation of the rights of others occurring since the age<br />

of fifteen. 2 Patients with this disorder must also meet three (or<br />

more) of the following:<br />

1. failure to conform to social norms with respect to lawful<br />

behaviors as indicated by repeatedly performing acts that<br />

are grounds for arrest<br />

2. deceitfulness, as indicated by repeated lying, use of<br />

aliases, or conning others for personal profit or pleasure<br />

3. irritability and aggressiveness, as indicated by repeated<br />

physical fights or assaults<br />

4. reckless disregard for safety of self or others<br />

5. consistent irresponsibility, as indicated by repeated<br />

failure to sustain consistent work behavior or honor financial<br />

obligations<br />

6. lack of remorse, as indicated by being indifferent<br />

to or rationalizing having hurt, mistreated, or stolen from<br />

another. 2<br />

This more nuanced pattern does not entirely fit any of the<br />

physicians whose crimes the profession would like to forget.<br />

<strong>The</strong> very act of choosing a career in medicine and completing<br />

medical school makes psychopathology at a level that<br />

encompasses mass murder untenable. Medicine is a profession<br />

entered as an adult with extensive emphasis on social norms<br />

and regulated, responsible behavior, and for which consistency<br />

in meeting numerous obligations is essential. While it<br />

is clear that something is grievously wrong with physicians<br />

like Mengele and his ilk, attributing even the most despotic<br />

18 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Dr. Karl Brandt at the Nuremberg trial.<br />

© dpa/Corbis<br />

of actions solely to psychiatric disease misses an essential, if<br />

unsettling, element of the dark side of physician behavior: they<br />

were once just like us.<br />

Nazi physician Karl Brandt was the director of the T-4<br />

euthanasia program that murdered thousands of Germans<br />

before it became the inspiration for the gas chambers of the<br />

death camps. At his trial at Nuremberg, Brandt said this:<br />

Would you believe that it was a pleasure to me to receive<br />

the order to start euthanasia? For fifteen years I had<br />

laboured at the sick-bed and every patient was to me like a<br />

brother, every sick child I worried about as if it had been my<br />

own. . . . With the deepest devotion I have tortured myself<br />

again and again, but no philosophy or other wisdom helped<br />

here. <strong>The</strong>re was the decree and on it there was my name. 3<br />

Before his execution by hanging, Brandt offered himself as<br />

the subject for medical experimentation. 3 His offer was rejected,<br />

but both his words and actions speak to the guilt and<br />

conflicted emotions of an individual who is clearly tormented,<br />

yet hardly insane. A trial with similar charges is set to start<br />

in March 2010, as Radovan Karadzic will have to answer for<br />

his role in orchestrating the slaughter of Bosnia’s Muslims.<br />

Karadzic has thus far refused to cooperate in his own defense,<br />

but the details of his evasion from capture for over a decade<br />

speak volumes. After he was apprehended, a New York Times<br />

profile sought out those who knew Karadzic as New Age<br />

healer Dragan Dabic. 4 Although most acknowledged the eccentricity<br />

of their new neighbor, no one made the connection<br />

between the bearded alternative medicine guru and the man<br />

once known as the Beast of Bosnia.<br />

When daylight came, Goran Kojic, the Healthy Life<br />

editor, wanted to talk one more time. He seemed the most<br />

troubled by the unresolvable contradictions of his recent<br />

life. Was the pose of gentle spiritualist a complete fake and a<br />

cover for a soul darkly outed as hideous, violent and bestial?<br />

Or was there some truth to Dabic’s character?<br />

“<strong>The</strong>re are two options,” said Kojic, cautiously, hesitantly,<br />

as if he were speaking for a nation. “Either we are all a bunch<br />

About the author<br />

I studied biochemistry and creative<br />

writing at the University of Arizona before<br />

enrolling in the medical scientist training<br />

program at Northwestern University.<br />

While in Chicago, I completed my PhD<br />

in cancer biology and graduated with the<br />

Feinberg School of Medicine Class of 2010. I am currently<br />

a resident in Internal Medicine at the Brigham<br />

and Women’s Hospital in Boston and plan to pursue a<br />

career as an oncologist. Interests include translational<br />

research but also medical humanities/narrative and<br />

health/science policy. I have been an online contributor<br />

to the Virginia Quarterly Review and have had medical<br />

narratives featured in the Journal of the American<br />

Medical Association and Health Affairs.<br />

of fools and madmen who believed<br />

in the existence of a nonexistent<br />

man.” Or, he said, there<br />

is the possibility of redemption. 4<br />

Those with personal knowledge of<br />

both Karadzic himself and the carnage<br />

he caused are unable to separate<br />

the threads of his identity. We<br />

do not have similar commentary<br />

from those who personally knew<br />

physician-suicide bombers, but<br />

these individuals did not live the<br />

life of the criminally insane. <strong>The</strong>y<br />

worked as physicians; some had<br />

families. Clearly, physicians who<br />

participate in political violence<br />

Dr. Radovan Karadzic<br />

© dpa/Corbis<br />

share the undeniable trait of humanity gone horribly awry, but<br />

this truth provides neither a final answer nor an excuse for the<br />

medical profession to settle for such an oversimplification.<br />

External pressure: the genuine grievance theory<br />

Another common explanation rationalizing physician<br />

atrocities on behalf of state or non-state actors is terrorism.<br />

Recasting the actions of certain physicians as rank-and-file<br />

terrorists can mask the need to probe the healer/destroyer<br />

dichotomy. Physician. Terrorist. What more need be said?<br />

Even though physicians spearheaded the establishment of<br />

many of the most violent terrorist groups in the Middle East<br />

in the 1960s and ’70s, their paradoxical role is rarely examined.<br />

Physician George Habash graduated from the American<br />

University of Beirut before he started the Popular Front for<br />

the Liberation of Palestine. 5 His political colleague and former<br />

medical school classmate, Dr. Wadih Haddid, 5 is the mastermind<br />

behind the hijacking of commercial airliners even before<br />

the horrors of September 11, 2001. Islamic Jihad was founded<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 19


<strong>The</strong> monsters of medicine<br />

Dr. George Habash<br />

© Bettmann/CORBIS<br />

Dr. Ikuo Hayashi<br />

AFP/Getty Images<br />

Dr. Wadih Haddid<br />

© Bettmann/CORBIS<br />

by yet another physician,<br />

Dr. Fathi Shiqaqi. 6 <strong>The</strong> Aum<br />

Shinrikyo sarin nerve gas attack<br />

on the Tokyo subway<br />

that made headlines around<br />

the globe probably would<br />

not have succeeded without<br />

the involvement of Dr. Ikuo<br />

Hayashi, a one-time rising<br />

star at the Japanese Ministry<br />

of Science and Technology. 7<br />

Even with the series of al-<br />

Qaeda-associated bombings<br />

perpetrated by physicians<br />

over the last five years from<br />

Glasgow in 2007 to Jordan<br />

in 2009, nearly all analyses of the attacks’ significance focus<br />

on the development and re-structuring of al-Qaeda tactics,<br />

not the startling (or so one would think) observation that<br />

physicians are so openly participating. <strong>The</strong> evidence is clear<br />

that the physician-terrorist is far from a unique construct, yet<br />

rather than explore this puzzling reality, in a leap of circular<br />

reasoning, the existence of such a duality has itself become a<br />

substitute explanation for it.<br />

Unfortunately, this approach also draws the medical community<br />

into acknowledging elements of the genuine grievance<br />

theory in an attempt to understand the unthinkable. While<br />

this perspective represents an important first step in any rootcause<br />

analysis, it may also legitimize terrorist acts. During a<br />

time in which the Palestinian cause was inextricably linked<br />

to violence targeting civilians, Yasser Arafat stood before the<br />

United Nations General Assembly and stated: “<strong>The</strong> difference<br />

between the revolutionary and the terrorist lies in the reason<br />

for which each fights. For whoever stands by a just cause . . .<br />

cannot possibly be called terrorist.” 8 His words are shocking,<br />

but they are also an uncanny echo of Menachem Begin, who<br />

wrote twenty years before: “the ideal is the important thing,<br />

not the man.” 9<br />

It is this seeming connection of the almost universally<br />

accepted ideal of freedom with terrorism that has led to the<br />

maxim: “Terrorism appears whenever people have genuine,<br />

legitimate grievances. Remove the grievances and terror will<br />

cease. Like all good lies, this statement cloaks itself in an<br />

almost-convincing mantle of truth. Indeed, an analysis of the<br />

personal lives of so-called physician-terrorists reveals more<br />

than one connection to some of the most turbulent events of<br />

recent history. George Habash and Wadih Haddid were young<br />

medical students when their families lost everything to the<br />

fledgling Israeli Army of 1948. 5 <strong>The</strong> desperation and suffering<br />

endured by generations of Palestinians living without hope or<br />

a future is a powerful stimulus for many elements of organized<br />

terror, both past and present. <strong>The</strong> same struggle for national<br />

independence can be seen at the root of the conflicts involving<br />

Algeria and the FLN, or Ireland and the IRA. Although not as<br />

direct a correlation, al-Qaeda propaganda uses the suffering of<br />

Muslim civilians in the Middle East as a powerful recruiting<br />

tool for many who have not themselves lived through the horrors,<br />

including physicians.<br />

But despite an accurate recognition of the value of justice<br />

and the unfortunate historical reality of injustice, the arguments<br />

forming the genuine grievance theory are based on a logic that<br />

is both unsound and a precept the medical profession should<br />

never accept as an explanation for the troubling existence of the<br />

physician-terrorist. Those who turn to terror undermine their<br />

own cause by denying the meaning and universality of the very<br />

principles to which they appeal. Even the most cherished ideals<br />

of freedom and self-determination cannot be used to legitimize<br />

a cause that only applies them in one direction. This is part of<br />

what makes the individual who wields a stethoscope in one hand<br />

and a bomb in the other so difficult to comprehend. Medicine<br />

as a profession is based on helping all those in need, a principle<br />

��������������������������������<br />

�����<br />

������������������������������������<br />

—Yasser Arafat<br />

������������������������<br />

�<br />

������������<br />

—Menachem Begin<br />

enshrined in one form or another in medical oaths spanning<br />

both geography and time. <strong>The</strong> Hippocratic Oath and its injunction<br />

to “first do no harm” is most familiar to the Western world,<br />

20 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


ut this concept is a universal one, paralleling the evolution of<br />

the physician as an individual with a unique and honored calling.<br />

<strong>The</strong> Charaka Samhita is an ancient Sanskrit text dating to<br />

the third century BCE which states, “Day and night, however<br />

thou mayest be engaged, thou shalt endeavor for the relief of<br />

patients with all thy heart and soul.” 10 What is thus so troubling<br />

for the medical profession is that one of its members could fully<br />

accept the responsibility of the physician but only as applied<br />

to a few select persons. Whatever the supposed grievance, the<br />

terrorist attempts to hide behind moral relativism even while<br />

claiming a monopoly on moral superiority, as in Yasser Arafat’s<br />

reference to Abu Nidal as “a real terrorist” after Nidal’s nearsuccessful<br />

assassination attempt against the PLO leader. 11 <strong>The</strong><br />

hypocrisy of any attempt to cling to a moral code one has shown<br />

no compunction in violating underscores the vital role that ethics<br />

plays in any analysis of terrorism, especially that perpetrated<br />

by physicians.<br />

And this is the second point the medical profession must<br />

acknowledge as we attempt to first understand and then prevent<br />

the actions of those who claim our calling but reject our<br />

creed. <strong>The</strong> justification used by physicians who take life to advance<br />

political goals—whether acting on behalf of the state or<br />

non-state actors—is unmistakably a moral decision that must<br />

be recognized as such before it can ever be rejected. Both religious<br />

and secular terrorists, as well as those acting on behalf<br />

of the state in cases of genocide, provide moral justification for<br />

their actions in a way that clearly rejects the universal value<br />

of individual human life that is at the heart of medicine. <strong>The</strong><br />

writings of Carlos Marighella have been translated into over<br />

a dozen languages and discovered in more than one hundred<br />

terrorist safe houses throughout the world; his Minimanual<br />

of the Urban Guerrilla states, “the urban guerrilla’s arms are<br />

inferior to the enemy’s, but from a moral point of view, the<br />

urban guerrilla has an undeniable superiority.” 12 <strong>The</strong> most<br />

important significance of this work for such a broad range of<br />

organizations lies in the conclusions that equate the legitimacy<br />

of a cause with the methods used to achieve it. This codified<br />

morality for the actions of a terrorist is one in which human<br />

life is not respected. His words horrify, yet it should not be<br />

surprising that upon learning his bomb destroyed German<br />

instead of Israeli tourists, the bombmaker responded, “Infidels<br />

are all the same.” 13 <strong>The</strong> difficulties in establishing a working<br />

definition of terrorism and even the use of the word as a<br />

descriptive label imply a moral judgment that can be used to<br />

wage a war of semantics against unwanted political behavior.<br />

But despite legitimate definitional challenges, the conscious<br />

choice to take life in defiance of the profession that stands<br />

for saving it is a moral decision framed by a rejection of the<br />

fundamental worth of the individual. It is only in recognizing<br />

this fact that the medical community can ask the difficult<br />

questions about itself that must be the first steps towards any<br />

attempt to combat such actions by physicians.<br />

Moving forward<br />

Reframing the infamous physicians as one who chooses to<br />

devalue human life—regardless of confounding psychiatric<br />

or political factors—raises two compelling questions for the<br />

medical profession with implications at the practical level.<br />

First, is there something about medical training that can<br />

lead to some physicians rejecting the value of human life?<br />

While the overarching values of the medical profession say<br />

absolutely not, a closer analysis of the day-to-day process of<br />

becoming a physician and practicing medicine suggests otherwise.<br />

From the very beginning of medical school, the training<br />

process demands would-be physicians put aside some of<br />

their most basic human instincts. As human beings, we draw<br />

away from death, from blood, from suffering, yet medical<br />

training demands that we embrace and sometimes even cause<br />

all of the above. What starts in the cadaver lab extends to the<br />

surgical theater, the chemotherapy clinic, and the radiation<br />

suite. <strong>The</strong> goal of practicing medicine is to support life, but<br />

in the process of doing so, physicians nonetheless act in a way<br />

that in any other setting would be unthinkable: we take knives<br />

to flesh, administer the deadliest of toxins, direct radiation to<br />

permanent harm. In other settings, each of these activities<br />

has been the basis for charges of crimes against humanity. In<br />

many settings, transplant surgery or experimental protocols<br />

among them, physicians can take on the role that throughout<br />

history has traditionally been granted only to God: determining<br />

who lives and who dies. <strong>The</strong> regulation of clinical trials<br />

and human experimentation has undergone dramatic development<br />

throughout the last decades, but even with the deep<br />

scrutiny of today’s IRB committees the role of directly experimenting<br />

on human subjects is an established part of modern<br />

medicine. No amount of preclinical development and testing<br />

can take away the fact that the goal of Phase I clinical trials is<br />

to identify toxicities in a human population.<br />

Clearly, most physicians complete their medical training<br />

without following the twisted path of one who uses it to<br />

destroy rather than heal. Yet the fact remains that a career in<br />

medicine forces one to confront questions of life, death, suffering,<br />

and healing at a level of intimacy that no other profession<br />

can match. Ironically, it is spiritual leaders who likely come the<br />

closest, and the relationship between organized religion and<br />

political violence needs no further elaboration here. In the setting<br />

of medical training, then, both the events of the past and<br />

the developments of today suggest that physicians—like those<br />

from any background of deep ideological convictions—may be<br />

vulnerable to radicalizing influences not in spite of their training<br />

but perhaps because of it. While this is a sobering reality<br />

to consider, it is also one that offers the promise of change.<br />

Medical training has undergone a remarkable transformation<br />

over the last decades, with an emphasis on ethics and professionalism<br />

in medical education as never before. We already<br />

have the tools to strengthen our commitment to respecting<br />

the humanity and dignity of all who cross our path—the challenge<br />

now before us is how best to utilize them. Just as an individual<br />

physician makes the choice about where her deepest<br />

allegiance lies, so too can the medical profession.<br />

This, in turn, raises a related point that can be all the more<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 21


<strong>The</strong> monsters of medicine<br />

difficult to recognize for its subtlety. Any discussion of political<br />

violence, war crimes, and terrorism must emphasize the deep<br />

ideological fervor of participants that permits participation in<br />

atrocities. But convictions of even the most deeply-held principles<br />

are in themselves neutral entities; only in their application<br />

do we truly see what an individual has chosen to reject or<br />

embrace. For every physician who joins the medical profession<br />

with a deep faith in a given principle only to emerge a monster,<br />

there are far more who use their values to shape a commitment<br />

to medicine into something of profound inspiration. Most telling<br />

of all, the potential for making positive rather than negative<br />

contributions can be seen in medical organizations that cut<br />

across the spectrum of religious and secular beliefs. <strong>The</strong> stated<br />

mission of Physicians for Human Rights is to “[mobilize] health<br />

professionals to advance health, dignity, and justice.” 14 For the<br />

strength of this commitment and its real-world application,<br />

the organization shared the 1997 Nobel Peace Prize. Two years<br />

later, Doctors without Borders, an organization “based on the<br />

humanitarian principles of medical ethics and impartiality”<br />

was recognized with this same award. 15 Furthermore, deep<br />

spiritual convictions do not automatically translate to fundamentalist<br />

hate. In this context, consider the example of the mission<br />

statements of the Islamic Medical Association of North<br />

America (IMANA) and the Christian Medical and Dental<br />

Association (CMDA). Both acknowledge the fundamental role<br />

of the Islamic or Christian faith, respectively, in the lives of<br />

their members. Both incorporate spiritual beliefs that are only<br />

accepted by members of their distinct faiths. Yet it is the deep<br />

and abiding respect for life on spiritual grounds in conjunction<br />

with a professional calling to medicine that also brings both<br />

organizations to a conclusion utterly repudiating the actions of<br />

those who claim a spiritual heritage to legitimize acts of great<br />

evil. <strong>The</strong> IMANA mission statement concludes with this verse<br />

from the Qur’an: “If anyone has killed one person (except in<br />

lieu of murder or mischief on earth) it is as if he has killed the<br />

whole of mankind, and if he has saved one life it is as if he saved<br />

the whole of mankind.” 16 <strong>The</strong> CMDA mission statement indicates<br />

that the organization exists to equip Christian physicians<br />

to, “pursue professional competence and Christ-like compassion<br />

in their daily work.” 17 <strong>The</strong> inspiration for such compassion<br />

is this injunction from the gospel of Mathew: “You shall love<br />

your neighbor as yourself.” 18<br />

It is these words—and others like them—that represent the<br />

true challenge facing the medical profession as we continue<br />

to struggle with the paradox of physicians who both heal and<br />

destroy. As a profession, we must understand our heritage and<br />

walk the very fine line of respecting the personal differences<br />

among us while refusing to compromise on the moral integrity<br />

on which medicine is based. We must challenge ourselves to<br />

treat all equally. We must recognize that principle always has<br />

a place in argument even while acknowledging that principles<br />

themselves can be hijacked and used to justify heinous acts of<br />

violence. In short, we must be physicians, first and always, but<br />

we must also be physicians who live in the real world and never<br />

lose sight of any opportunity—from improving medical education<br />

to supporting humanitarian medical aid—to emphasize<br />

the uncompromising foundation of respect for humanity on<br />

which our profession is built. This approach will not remove<br />

every threat to the integrity of the physician posed by political<br />

violence, but it does provide a place to start from the only<br />

perspective that matters: one life at a time.<br />

References<br />

1. Wilkinson P. Terrorism and the Liberal State. Second edition.<br />

New York: New York University Press; 1986.<br />

2. American Psychiatric Association. DSM-IV-TR Diagnostic<br />

Criteria for Antisocial Personality Disorder (301.y). In: Diagnostic<br />

and Statistical Manual of Mental Disorders. Fourth edition. Washington<br />

(DC): American Psychiatric Association; 1994.<br />

3. Spartacus Educational web site. Karl Brandt. www.spartacus.<br />

schoolnet.co.uk/GERbrandtK.htm.<br />

4. Hitt J. Radovan Karadzic’s new-age adventure. New<br />

York Times 2009 Jul 22. www.nytimes.com/2009/07/26/<br />

magazine/26karadzic-t.html.<br />

5. Habash G, Soueid M. Interview: Taking stock: An interview<br />

with George Habash. J Palestinian Stud 1998; 28: 86–101.<br />

6. Greenberg J. Islamic group vows revenge for slaying<br />

of its leader. New York Times 1995 Oct 30: A9. www.nytimes.<br />

com/1995/10/30/world/islamic-group-vows-revenge-for-slaying-ofits-leaders.html.<br />

7. Murakami H. Underground: <strong>The</strong> Tokyo Gas Attack and the<br />

Japanese Psyche. New York: Vintage; 2001.<br />

8. Richardson L. What Terrorists Want: Understanding the<br />

Enemy, Containing the Threat. New York: Random House; 2007.<br />

9. Laqueur W, editor. <strong>The</strong> Terrorism Reader: A Historical Anthology.<br />

New York: New American Library; 1978.<br />

10. Menon LA, Haberman HF. <strong>The</strong> medical students’ oath of<br />

ancient India. Med Hist 1970; 14: 295–99.<br />

11. Harmon C. Terrorism Today. London: Frank Cass; 2000: 191.<br />

12. Marighella C. Minimanual of the urban guerrilla. New World<br />

Liberation Front; 1970.<br />

13. Hoffman B. Inside Terrorism. New York: Columbia University<br />

Press; 1998: 168.<br />

14. Physicians for Human Rights web site. About PHR. physiciansforhumanrights.org/about/.<br />

15. Doctors Without Borders web site. About Us—History and<br />

Principles. www.doctorswithoutborders.org/aboutus/.<br />

16. Islamic Medical Association of North America web site. Mission<br />

and Vision. www.imana.org/index.php?option=com_content&v<br />

iew=article&id=196&Itemid=65.<br />

17. Christian Medical and Dental Association web site. Mission<br />

& Beliefs. www.cmda.org/WCM/CMDA/Navigation/About/MissionsBeliefs/Missions_Beliefs.aspx.<br />

18. <strong>The</strong> Holy Bible Containing the Old and New Testaments<br />

New King James Version. Nashville (TN): Thomas Nelson Publishers;<br />

1982: 873.<br />

<strong>The</strong> author’s e-mail is: aredig@partners.org<br />

22 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Sestina on Limb-Lengthening<br />

Surgery<br />

John’s father was a famous novelist,<br />

his mom a musical sensation. In short,<br />

John was born with two silver spoons in mouth.<br />

A bright boy, he sailed through Harvard, then<br />

demonstrated<br />

valor in the Horn of Africa. A great<br />

career in politics awaited; the only<br />

obstacle was John’s stature: he was only<br />

five-foot-two, puny as a sapling that lists<br />

whichever way the wind blows. For a great<br />

price, John secured the services of a shortspoken<br />

but skilled cosmetic surgeon, who operated<br />

on John’s bones to make him taller, so his mouth<br />

could speechify from a loftier place. <strong>The</strong> mouth<br />

of conventional wisdom says that only<br />

females are vain, preening in front of crenellated<br />

mirror frames, making lengthy shopping lists<br />

of perfumes, lipsticks, skirts, and shorts;<br />

but masculine vanity is no less great.<br />

My friend Millie, whose voice is apt to grate,<br />

but who has pretty eyes and a sweet mouth,<br />

helped me see why this is the long-and-short<br />

of the matter. She tells me that she only<br />

dates boys who are at least five-foot-ten, lest<br />

their offspring’s height be too modest, too understated.<br />

Where prejudices of this kind are indurated,<br />

it’s no surprise that male vanity is great.<br />

<strong>The</strong> man I date, the man who tops the list<br />

of men in my life, with his honest mouth<br />

says that his brothers tower over him only<br />

because he is a twin: he has been short<br />

ever since he, together with his short<br />

sister, inhabited their mom’s trabeculated<br />

womb. He regrets his shortness, saying, “If only<br />

I were taller . . . ,” while the fire in the grate<br />

backlights the beauty of his face; his mouth,<br />

nose, eyes all vie for which is loveliest<br />

to me. My stammering mouth replies at last,<br />

“My patient, John, could have been great if only<br />

a complicated surgery hadn’t cut his life short.”<br />

Jenna Le<br />

Ms. Le is a member of the Class of 2010 at the Columbia University<br />

College of Physicians and Surgeons. This poem won first prize in the 2010<br />

<strong>Pharos</strong> Poetry Competition. Ms. Le’s e-mail address is: jenna.le@gmail.com.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 23


Dean Gianakos, MD<br />

B������������<br />

What poetry has to say about it<br />

<strong>The</strong> author is the associate director of the Lynchburg Family<br />

Medicine Residency in Lynchburg, Virginia, and a member<br />

of the editorial board of <strong>The</strong> <strong>Pharos</strong>.<br />

Breaking bad news to patients is difficult. Even experienced<br />

physicians struggle to do it competently. Until<br />

recently, it’s a skill that has received little attention<br />

in medical schools, residencies, and fellowship training programs.<br />

1 <strong>The</strong>re is scant evidence on how to do it well. 2,3 Most<br />

articles on the subject refer to certain steps that may be helpful:<br />

create a comfortable setting for patients and families; find<br />

out what patients know about their condition; ask them how<br />

much they desire to know; deliver the news in a clear, concise<br />

fashion; show empathy; be prepared to respond to various<br />

reactions to the news—sadness, denial, anger, or guilt; and,<br />

finally, summarize and outline a plan for the patient. 3–5<br />

Experience, frequent practice, coaching from mentors,<br />

and reviewing the medical literature are traditional ways to<br />

improve one’s ability to deliver bad news. I believe reading<br />

poetry is another way: reading poems with care and empathy<br />

fosters an appreciation of the importance of language, feelings,<br />

and nuance in communication and relationships. Raymond<br />

Carver’s poem, “What <strong>The</strong> Doctor Said,” offers insights into<br />

patient-physician relationships not found in other forms of<br />

instruction. In this poem, Carver shows how difficult, frightening,<br />

and awkward (for the patient and physician) delivering<br />

and receiving bad news can be:<br />

He said it doesn’t look good<br />

he said it looks bad in fact real bad<br />

he said I counted thirty-two of them on one lung before<br />

I quit counting them<br />

I said I’m glad I wouldn’t want to know<br />

about any more being there than that<br />

he said are you a religious man do you kneel down<br />

in forest groves and let yourself ask for help<br />

when you come to a waterfall<br />

mist blowing against your face and arms<br />

do you stop and ask for understanding at those moments<br />

I said not yet but I intend to start today<br />

he said I’m real sorry he said<br />

I wish I had some other kind of news to give you<br />

I said Amen and he said something else<br />

I didn’t catch and not knowing what else to do<br />

and not wanting him to have to repeat it<br />

and me to have to fully digest it<br />

I just looked at him<br />

for a minute and he looked back it was then<br />

I jumped up and shook hands with this man who’d just given<br />

me<br />

something no one else on earth had ever given me<br />

I may have even thanked him habit being so strong 6<br />

<strong>The</strong> doctor in the poem botches it—badly. 7 In his first<br />

attempt to deliver the news, he tries a detached, scientific approach:<br />

he counts. Not only does he count the nodules; he reports<br />

the number to the patient—the number before he stops<br />

counting. Ten, twenty, or thirty-two nodules—what clinical<br />

difference does it make? <strong>The</strong>n he resorts to quasi-religious,<br />

poetic imagery: “do you kneel down in forest groves and let<br />

yourself ask for help when you come to a waterfall, mist blowing<br />

against your face and arms.” I’m fine with asking patients<br />

if they are religious, but does anyone want this question after<br />

being told they have more than “thirty-two of them on one<br />

lung”?<br />

24 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


<strong>The</strong> truth is, most of us blunder from time to time, no<br />

matter how experienced we are in communicating serious<br />

news. We come prepared with the words that soothe—“this<br />

must be very difficult for you; I cannot imagine how you must<br />

feel”—only to utter stupid, insensitive things. And sometimes<br />

the patient saves us from ourselves. He feels the doctor’s discomfort<br />

in breaking the news, and works to ease the doctor’s<br />

pain, jumping up and even thanking him!<br />

Every time I read this poem, I feel uncomfortable. I squirm<br />

as the anxious physician who cannot find the right words<br />

Illustrations by Erica Aitken<br />

to communicate in an honest, sensitive way. I squirm as the<br />

patient who suffers through not only the news about a devastating<br />

diagnosis, but also the nonsense coming from the<br />

physician’s mouth. What could the physician in Carver’s poem<br />

have done differently? What can any of us do when we realize<br />

the conversation is going badly? After his first verbal blunder,<br />

maybe the physician should have said something like: “I’m not<br />

saying this very well; let me start over.” Maybe he should have<br />

started the conversation with “I wish I had some other kind<br />

of news to give you,” and then quietly waited for the patient’s<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 25


Breaking bad news<br />

response after delivering the diagnosis. Things might have<br />

gone differently. Perhaps not. At many points in the dialogue,<br />

I simply want the physician to stop talking. And maybe that is<br />

one of the major lessons of the poem.<br />

Dr. John Stone’s poem “Talking to the Family” delivers<br />

other insights:<br />

My white coat waits in the corner<br />

like a father.<br />

I will wear it to meet the sister<br />

in her white shoes and organza dress<br />

in the live of winter,<br />

the milkless husband<br />

holding the baby.<br />

I will tell them.<br />

<strong>The</strong>y will put it together<br />

and take it apart.<br />

<strong>The</strong>ir voices will buzz.<br />

<strong>The</strong> cut ends of their nerves<br />

will curl.<br />

I will take off the coat,<br />

drive home,<br />

and replace the light bulb in the hall. 8<br />

<strong>The</strong> physician’s fear of doing his duty is palpable. Like a boy<br />

who dreads telling his father about an accident or other bad<br />

news, but knows he must, the physician reluctantly puts on<br />

his white coat of authority to inform the family of the patient’s<br />

death. As Kathryn Montgomery beautifully puts it,<br />

the secret of the poem, the reason its speaker is not the<br />

heartless bastard a first-year student every now and then<br />

will argue he must be, is that, except for the first line, it is<br />

written in the future tense. . . . <strong>The</strong> dreadful telling has not<br />

happened yet. <strong>The</strong> speaker is still elsewhere, off stage, in his<br />

office perhaps, and the dread—along with the acceptance of<br />

a physician’s duty—is his. 9<br />

Despite the tragedy, life goes on. <strong>The</strong> physician cannot<br />

dwell on the moment—he has other patients to see, and other<br />

patients to console. He also has other things to do. Doctoring<br />

is only one of his roles. <strong>The</strong> doctor slips on his white coat at<br />

work, and slips it off when his professional duty is done. He<br />

goes home and, like the rest of us, must perform mundane<br />

tasks such as changing light bulbs.<br />

<strong>The</strong> simple, mechanical task takes his mind off the terrible<br />

news. Changing the light bulb is an important step toward<br />

focusing on the present, renewing his energy, and healing<br />

his own pain. <strong>The</strong> light goes out in one life, but the doctor<br />

is climbing the ladder again, making physical and emotional<br />

adjustments so that he can bring new life and light to others.<br />

Life goes on.<br />

Physicians need to be intellectually and emotionally prepared<br />

to deliver bad news. Patients and families may have<br />

many questions about treatment and prognosis. <strong>The</strong>y may<br />

react to the news in a variety of ways, including sadness, anger,<br />

or shock. And physicians themselves will have their own<br />

reactions to the telling of the news. But preparation for these<br />

things is not sufficient. Once they are in the middle of a conversation,<br />

physicians must be flexible, creative, and self-aware,<br />

ready if necessary to change the direction of the dialogue, offer<br />

a tissue, or simply be quiet. Like Stone’s poem, what’s left<br />

unsaid often has more power than what is said: Stone does not<br />

explicitly tell us about the husband’s grief—he uses a remarkable<br />

image, “the milkless husband holding the baby,” to convey<br />

the impending grief and loss.<br />

Reading the poems above is no substitute for preparation,<br />

practice, and clinical experience. Nevertheless, I believe<br />

physicians who read these poems with attention and empathy<br />

will enhance their understanding of language, feelings, and<br />

the communication of bad news. <strong>The</strong> poems also remind us<br />

how unpredictable these conversations can be, no matter how<br />

frequently we rehearse for them. Finally, we should not be surprised<br />

by our dread and reluctance to do our duty and deliver<br />

the message: a milkless husband is hard to bear.<br />

References<br />

1. Hebert HD, Butera JN, Castillo J, Mega AE. Are we training<br />

fellows adequately in delivering bad news to patients? A survey of<br />

hematology/oncology program directors. J Palliat Med 2009; 12:<br />

1119–24.<br />

2. Walsh RA, Girgis A, Sanson-Fisher RW. Breaking bad news.<br />

2: What evidence is available to guide clinicians? Behav Med 1998;<br />

24: 61–72.<br />

3. Barclay JS, Blackhall LJ, Tulsky JA. Communication strategies<br />

and cultural issues in the delivery of bad news. J Palliat Med 2007;<br />

10: 958–77.<br />

4. Back A, Arnold R, Tulsky J. Mastering Communication with<br />

Seriously Ill Patients: Balancing Honesty with Empathy and Hope.<br />

Cambridge: Cambridge University Press; 2009.<br />

5. Ptacek JT, Eberhardt, TL. Breaking bad news: A review of the<br />

literature. JAMA 1996; 276: 496–502.<br />

6. Carver R. All Of Us: <strong>The</strong> Collected Poems. New York: Vintage<br />

Books; 2000: 289.<br />

7. Gianakos D. What the Doctor Said: Commentary. Acad Med<br />

2008; 83: 420–21.<br />

8. Stone J. Music From Apartment 8. Baton Rouge (LA): Louisiana<br />

State University Press; 2004: 51.<br />

9. Montgomery K. A setback: In memory of John Stone, 1936–<br />

2008. Lit Med 2008 Fall; 27: 119–23.<br />

<strong>The</strong> author’s address is:<br />

Lynchburg Family Medicine Residency<br />

2323 Memorial Avenue, #10<br />

Lynchburg, Virginia 24501<br />

E-mail: deangianakos@yahoo.com<br />

26 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


���������<br />

A heart aches<br />

Like the earth when it quakes<br />

A void left where ground once lay<br />

Impossible to heal<br />

A scar fills the space<br />

With memories that once were real<br />

John Allan, MD<br />

Dr. Allan (AΩA, Saint Louis University, 2009)<br />

is a PGY-2 in Internal Medicine at New York-<br />

Presbyterian Hospital Weill-Cornell Medical Center.<br />

His address is: 445 East 68th Street, Apartment 8G,<br />

New York, New York 10065. E-mail: allanj@slu.edu.<br />

Illustration by Jim M’Guinness<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 27


�����<br />

�������<br />

�������<br />

�������<br />

Early standardization of the insulin unit<br />

Barry Fields, MD<br />

28 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


<strong>The</strong> author is chief resident in<br />

Internal Medicine at the Yale<br />

Primary Care Residency Program.<br />

From its advent in September<br />

2006 until its removal from the<br />

market in October 2007, inhaled<br />

insulin for diabetes mellitus<br />

represented the first effective alternative<br />

to subcutaneous injections in<br />

more than eighty years. Aside from<br />

its administration modality, Exubera<br />

(Insulin Human [rDNA origin]) also<br />

transformed dosage labeling from<br />

the traditional insulin “unit” into<br />

milligrams. While this conversion<br />

may have appeared novel, it actually<br />

harked back to a time early in insulin<br />

therapy’s history. Indeed, defining insulin<br />

quantity in terms of milligrams<br />

sits at the heart of post-World War I<br />

efforts to ensure the new product’s<br />

safety and reliability. <strong>The</strong>se early attempts<br />

at its international standardization<br />

laid the foundation on which<br />

insulin dosage is still based today.<br />

Frederick Grant Banting.<br />

Courtesy of the National Library of Medicine.<br />

Producing an insulin extract<br />

In the autumn of 1920, Canadian<br />

surgeon Frederick Grant Banting<br />

scribbled,<br />

Diabetus<br />

Ligate pancreatic ducts of<br />

dog. Keep dogs alive till acini<br />

degenerate leaving Islets.<br />

Try to isolate the internal secretion<br />

of these to relieve glycosurea<br />

[sugar in the urine]. 1p50<br />

In this short note, Banting<br />

outlined how he would<br />

find the quintessentialtreatment<br />

for a disease he could not even spell.<br />

Over the next year, Banting worked<br />

in the University of Toronto physiology<br />

laboratory of Professor J. J. R.<br />

Macleod. With the help of graduate<br />

students Charles Best and Clark<br />

Noble, he purified his first insulin extract<br />

from the degenerating pancreases<br />

of canine subjects and showed it<br />

could transiently reduce the animals’<br />

blood sugar.<br />

Banting presented his findings to<br />

the American Physiological Society<br />

conference in December 1921. Among<br />

attendees expressing interest in extract<br />

production was George H. A.<br />

Clowes, research director for the Eli<br />

Lilly Pharmaceutical Company of<br />

Indianapolis. Though his offer was<br />

initially turned down, it caused the<br />

researchers to patent their process<br />

to maintain their control over the<br />

integrity of the extract’s manufacture<br />

and purification. <strong>The</strong> University of<br />

Toronto’s Board of Governors subsequently<br />

licensed the process to Lilly’s<br />

laboratories. 1 American production<br />

supplemented the relatively meager<br />

yields at Toronto’s own Connaught<br />

Antitoxin Laboratories, supplying<br />

a burgeoning international market<br />

with insulin therapy.<br />

To oversee insulin’s future licensing<br />

and distribution, the Board<br />

of Governors organized Toronto’s<br />

Insulin Committee (IC) in 1922. One<br />

of its first actions was to offer patent<br />

rights to the British Medical Research<br />

Council (MRC), thus giving Europe<br />

its first access to insulin. <strong>The</strong> MRC<br />

sent Dr. Henry H. Dale, a department<br />

director at their National<br />

Institute for Medical Research, to<br />

Toronto. Dale quickly recognized the<br />

promise of insulin and suggested the<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 29


From rabbits to the League of Nations<br />

MRC accept control of the British patent.<br />

At the same time, he and his traveling<br />

companion, biochemist Harold W.<br />

Dudley, expressed serious reservations<br />

regarding the IC’s earliest definition of<br />

the insulin unit. Dale wrote:<br />

<strong>The</strong> Toronto definition of a “unit”<br />

of the specific insulin activity, was<br />

the dose required, with intravenous<br />

injection, to throw 3 out of 5 rabbits<br />

into hypoglycaemic convulsions! I<br />

had made it no secret, from the first,<br />

. . . that I regarded such a definition<br />

as having so little claim to accuracy,<br />

as to be practically almost useless,<br />

and eventually misleading. 2p445<br />

Clowes from Lilly later echoed these<br />

misgivings when developing a reliable<br />

insulin unit became a matter of international<br />

concern.<br />

A rabbit-based unit<br />

Dale’s observation came months after<br />

the first insulin unit was defined.<br />

During the spring of 1922, Macleod,<br />

James B. Collip, Banting, and Best began<br />

calibrating insulin by its effects on animals.<br />

Using two-kilogram rabbits, they<br />

determined that hypoglycemic convusions<br />

usually appeared as the animals’<br />

blood sugar component fell below 0.045<br />

percent. This observation served as a<br />

threshold on which to base the first<br />

“physiologic unit” or “rabbit unit” of insulin,<br />

about one cc. <strong>The</strong> authors wrote:<br />

As a tentative basis for the physiological<br />

assay of insulin we consider<br />

as one unit the number of<br />

cubic centimeters which causes the<br />

blood sugar of normal rabbits to fall<br />

to 0.045 per cent within 4 hours.<br />

This dose is decidedly active in lowering<br />

the blood sugar in diabetic<br />

patients. 3p175<br />

<strong>The</strong>ir report also compared the effects<br />

of infused insulin solution on a<br />

two-kilogram normal rabbit with an<br />

eleven-kilogram depancreatized dog.<br />

<strong>The</strong> authors noted that, after taking<br />

into account the animals’ weight and<br />

dosage disparities, the dog still showed a<br />

much more dramatic reduction in blood<br />

sugar levels after having received only<br />

one third the dose that the rabbit had<br />

received. 3 <strong>The</strong> unit’s value would change<br />

later that year to reflect this observation.<br />

<strong>The</strong>se early attempts to define an<br />

insulin unit coincided with the first<br />

diabetic human patients being treated<br />

with the pancreatic extract. Fifteenyear-old<br />

Elizabeth Hughes, the diabetic<br />

daughter of New York governor<br />

and future Chief Justice Charles Evans<br />

Hughes, began her injections in mid-<br />

August. Just one cc twice daily effectively<br />

cleared the sugar from her urine.<br />

However, by October her dosage had<br />

risen to five cc twice daily. In a letter to<br />

her mother, Hughes wrote:<br />

Courtesy of the National Library of Medicine.<br />

30 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Charles H. Best.<br />

Courtesy of the National Library of Medicine.<br />

We only have a two cc. syringe you<br />

know and so Blanche [her nurse]<br />

fills that and gives it to me and then<br />

unscrews it from the needle which<br />

is left sticking in to me (I feel like a<br />

pincushion) fills it again, and gives<br />

me that (am left a pincushion once<br />

more), and then have the fifth cc.<br />

It really is quite a process, and altogether<br />

takes about twenty minutes<br />

for the whole performance. 1p155<br />

<strong>The</strong>re is no indication that Elizabeth<br />

Hughes’s diabetes had worsened, nor<br />

that her sensitivity to insulin had decreased.<br />

Since she remained in Toronto<br />

for the first months of treatment, it is<br />

almost certain she received her insulin<br />

from the same source, Connaught<br />

Antitoxin Laboratories. A lack of consistency<br />

in production protocol and<br />

continued efforts to increase their yield<br />

resulted in wide fluctuation<br />

in the final product’s<br />

activity. <strong>The</strong>refore, while<br />

Canadian researchers held<br />

the definition of an insulin<br />

unit constant in terms of<br />

its clinical effects on rabbits,<br />

the actual dosage fluctuated<br />

greatly. 1<br />

An ever-evolving unit<br />

Late in 1922, additional<br />

criticism of the definition<br />

of the insulin unit emerged<br />

from giants in American<br />

diabetology such as Dr.<br />

Frederik Madison Allen<br />

and Dr. Elliot P. Joslin.<br />

<strong>The</strong>se physicians and their<br />

colleagues disliked the<br />

“physiologic unit” of insulin<br />

because its relative<br />

strength in humans forced<br />

some patients to receive<br />

fractions of a unit, creating<br />

confusion among patients<br />

and nurses alike. 4 Clowes<br />

at Lilly brought their<br />

concerns to the IC. On<br />

December 30, 1922, they<br />

announced:<br />

<strong>The</strong> Toronto Committee conferred<br />

with Drs Clowes, Allen and Joslin as<br />

to the adoption of a unit for Insulin<br />

required to lower the blood sugar<br />

and the following conclusions were<br />

arrived at:<br />

1) <strong>The</strong> unit adopted for Insulin<br />

shall be approximately one-fifth that<br />

of the original Toronto unit, which<br />

is the amount of Insulin required to<br />

lower the blood sugar of a 2 kg fed<br />

rabbit 0.045 per cent within four<br />

hours, and cause symptoms. 4<br />

This new unit was to be called the “clinical<br />

unit” of insulin as opposed to the<br />

original “physiological,” “Toronto,” or<br />

“rabbit” unit. In this manner, the IC<br />

had adjusted its calibration of insulin to<br />

accommodate the needs of clinicians,<br />

as represented by Lilly. Further col-<br />

laborations between the pharmaceutical<br />

company and the IC would not proceed<br />

as smoothly.<br />

As with Elizabeth Hughes’s insulin<br />

supply, clinicians in 1923 complained of<br />

potency discrepancies among batches<br />

supposedly of the same clinical strength.<br />

California physician W. D. Sansum and<br />

his research team provided unique insight<br />

into the unit’s evanescence. During<br />

early 1923, they helped establish the<br />

“sugar-metabolizing power” of a given<br />

lot of insulin—the amount of sugar metabolized<br />

by each insulin unit. <strong>The</strong>y<br />

showed Lilly’s insulin to have 1.25 grams<br />

of sugar metabolizing power per unit. 5<br />

Unfortunately, clinicians and their patients<br />

remained vulnerable to continued<br />

unit modifications elsewhere.<br />

Beginning in May, the researchers<br />

noted that previously well-controlled<br />

diabetic patients had sugar reappearing<br />

in their urine. <strong>The</strong> new insulin<br />

units’ sugar metabolizing power had<br />

decreased by approximately one third<br />

compared to one month previously. <strong>The</strong><br />

authors state:<br />

We then learned that the unit had<br />

been redefined as being one-third<br />

of the amount required to lower<br />

the blood sugar below 0.045% and<br />

cause convulsions in a two-kilogram<br />

rabbit which had been previously<br />

starved for twenty-four hours. This<br />

redefinition was based on the belief,<br />

supported by experimental evidence,<br />

that it requires four times as<br />

much insulin to cause a convulsion<br />

in a two kilogram rabbit as in a<br />

one kilogram rabbit. In using onethird<br />

instead of one-fourth the convulsion<br />

[dose] in the two kilogram<br />

rabbits, these workers believed that<br />

they were increasing the value of<br />

the unit. 5<br />

<strong>The</strong>ir comments allude to discrepancies<br />

in rabbit size between Lilly’s laboratories<br />

and those of the IC. While Toronto<br />

had been using two-kilogram fed rabbits<br />

in its tests of potency, Lilly had<br />

been using one-kilogram fasting rabbits.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 31


From rabbits to the League of Nations<br />

To complicate matters further, Clowes<br />

never applied the IC’s new definition of<br />

the clinical unit to his product. Instead<br />

of dividing the physiologic unit by five<br />

per their directive, Clowes divided it<br />

by four and added twenty-five percent<br />

to account for product deterioration.<br />

He cited discrepancies in experimental<br />

results between Lilly and the IC and the<br />

tendencies of clinicians to desire a more<br />

potent unit to rationalize his decision. 4<br />

With an increasingly reliable extract<br />

provided by the IC and Lilly, attention<br />

could shift toward improving its international<br />

standardization.<br />

A weight-based standardization<br />

scheme<br />

A standardized drug is one that is<br />

always produced at equal potency in all<br />

manufactured lots. An international effort<br />

to standardize emerging treatments<br />

had been underway for decades before<br />

insulin was developed. Without knowing<br />

the chemical composition of these<br />

new biologic extracts, tests to determine<br />

potencies were relative; the substance’s<br />

effect on one group of animals (or “biological<br />

system”) would be compared to<br />

its effects on another reference or “standard”<br />

system. This procedure, however,<br />

assumed that the substance being tested<br />

and the animals in each test group were<br />

identical, an untenable assumption. 6,7<br />

As Lilly’s rabbits had demonstrated,<br />

standardization based solely on a reference<br />

biological system was fraught with<br />

dangerous inaccuracy.<br />

In 1897, German physician Paul<br />

Ehrlich described attempts at medical<br />

standardization based on activity<br />

of a certain weight of active ingredient.<br />

His task had been to ensure uniform<br />

potency of the newly-developed<br />

diphtheria antitoxin; due to the instability<br />

of the diphtheria toxin, he was<br />

consistently unsuccessful. Recognizing<br />

the fallibility of the biological system,<br />

he devised a standardization scheme<br />

based on weight of dried antitoxin. His<br />

institute in Germany kept samples of<br />

the sterile, dried product in vacuum at<br />

low temperature. Units of antisera were<br />

defined in terms of the weight of this<br />

standard. Laboratories and production<br />

plants around the world could periodically<br />

obtain samples and compare them<br />

to their new product to ensure the potency<br />

of its unit matched the standard<br />

in Germany.<br />

<strong>The</strong> MRC’s Henry Dale studied<br />

Ehrlich’s principles during a period in<br />

which he became increasingly frustrated<br />

with the international community’s attempt<br />

to standardize many medical<br />

breakthroughs. Efforts to institute unit<br />

standards consisted mostly of debates<br />

concerning the merits of one biological<br />

method over another. 8 With Dale’s<br />

encouragement, the League of Nations<br />

Health Committee sponsored a 1923<br />

Edinburgh Conference to discuss new<br />

methods of international standardization.<br />

In the months before the conference,<br />

Dale directed Dudley to prepare a<br />

solid form of insulin, resulting in insulin<br />

hydrochloride, a dried powder standard<br />

that companies and laboratories could<br />

compare their product against.<br />

<strong>The</strong> League of Nations weighs in<br />

When the International Congress<br />

met at Edinburgh in 1923, champions<br />

of biological systems proposed extending<br />

rodent hypoglycemia methods to<br />

international acceptance. Dale objected,<br />

citing the many drawbacks of such systems.<br />

He wrote:<br />

the definition, for permanent adoption<br />

and international transmission,<br />

of any unit of biological activity in<br />

terms of the reaction of a proportion<br />

of test animals, was inadmissible;<br />

and that the only safe basis for the<br />

definition of a unit of insulin, or of<br />

any other potent remedy, would be<br />

in terms of a precise weight of a<br />

standard, stable sample of the remedy<br />

in question, in the form of a<br />

completely dried powder. 2p448<br />

After displaying a vial containing the<br />

insulin hydrocholoride Dudley had developed,<br />

Dale proposed that interested<br />

parties work to correlate amounts of the<br />

powder with what they believed to be<br />

the experimental activity of one insulin<br />

unit. He also suggested they ask the<br />

League of Nations for another conference<br />

in two years, at which investigators<br />

taking part in the trials could present<br />

their findings.<br />

Reorganization within the League of<br />

Nations helped make that future conference<br />

a viable reality. In 1924, the League<br />

of Nations Health Committee became<br />

its Health Organization, one of several<br />

“technical agencies” that functioned<br />

semi-autonomously within the League. 9<br />

Its president, Thorvald Madsen, placed<br />

biological standardization near the top<br />

of his priority list for world health initiatives.<br />

7 <strong>The</strong>se developments within the<br />

League, combined with ever-increasing<br />

numbers of new biological compounds,<br />

set the groundwork for a Second<br />

International Conference on Biological<br />

Standards at Geneva in 1925.<br />

In the interim, five institutions, including<br />

Connaught Laboratories and<br />

Lilly, contributed samples of their insulin<br />

product to a growing pool of extract<br />

at the MRC. Under Dale and Dudley’s<br />

supervision, the preparations were combined<br />

and then converted to a single<br />

batch of powdered insulin hydrochloride.<br />

<strong>The</strong> product was divided into 100mg<br />

ampules, dried, sealed, and sent to<br />

laboratories in England, Canada, and<br />

the United States. Those independent<br />

labs could determine the value of “solid”<br />

insulin in terms of their own units at<br />

the time. <strong>The</strong>ir results were remarkably<br />

consistent, showing each milligram of<br />

powder to have a value of 8.4 to 8.8<br />

units. To avoid fractional units, the IC<br />

declared that the solid insulin standard<br />

contained 8 units per milligram. 10<br />

<strong>The</strong> Second International Conference<br />

met in late August and early September<br />

of 1925. Chaired by Henry Dale, it considered<br />

the standardization of several<br />

biological products, with insulin receiving<br />

particular attention. <strong>The</strong>ir unanimous<br />

recommendation read:<br />

That the dry preparation of insulin<br />

hydrochloride, prepared by<br />

the Medical Research Council of<br />

Great Britain at the request of the<br />

Edinburgh Conference, should be<br />

32 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


accepted as the international standard<br />

preparation of insulin. That 1<br />

milligram of this standard contains<br />

8 units of insulin (or 1 unit = 0.125<br />

milligrams), as provisionally defined<br />

by the Insulin Committee of the<br />

University of Toronto. 8p61<br />

<strong>The</strong> League of Nations’ Permanent<br />

Commission on Biological Standards<br />

subsequently adopted this recommendation.<br />

In doing so, the insulin unit<br />

was transformed from being defined by<br />

rodent convulsions to one determined<br />

by comparison to an internationally<br />

recognized standard preparation, in<br />

milligrams.<br />

Over the next decade, decreases<br />

in the use of the standard preparation<br />

method and further advances<br />

in insulin purification led world authorities<br />

to seek a new standard insulin<br />

unit. 10 In 1935, the League of<br />

Nations Permanent Commission on<br />

Biological Standardisation “accepted<br />

the new standard for international<br />

use and redefined the unit of insulin<br />

as the specific insulin activity of one<br />

twenty-second (1/22) of a milligramme<br />

of the new standard.” 11p486 A Third and<br />

Fourth International Standard would<br />

be elucidated under the World Health<br />

Organization, United Nations’ equivalent<br />

to the League of Nations Health<br />

Organization. Remarkably similar to the<br />

1935 standard, the Fourth International<br />

Standard defines biologically extracted<br />

insulin as 24.0 insulin units per milligram.<br />

10<br />

<strong>The</strong>refore, more than eighty years<br />

after a unit-milligram equivalency was<br />

first created to ensure international insulin<br />

standardization, this concept was<br />

resurrected to simplify inhaled insulin<br />

dosing and administration in a new<br />

form. Tables on Pfizer’s Exubera web<br />

site and in print aided clinicians and<br />

their patients in making this contemporary<br />

unit-to-milligram conversion<br />

(Pfizer’s web page for Exubera has been<br />

removed; a web page with similar information<br />

is referenced). 12 In doing so,<br />

they also brought to mind a historical<br />

definition—that of the insulin unit itself.<br />

Henry H. Dale.<br />

Courtesy of the National Library of Medicine. F. Netter, compliments Armour Laboratory, Chicago.<br />

Acknowledgment<br />

I thank my faculty advisors Stephanie<br />

Brown-Clark, MD, PhD, and Michael Green,<br />

MD, MSc, for their thoughtful comments,<br />

guidance, and support in preparation of this<br />

manuscript.<br />

References<br />

1. Bliss M. <strong>The</strong> Discovery of Insulin.<br />

Chicago: <strong>The</strong> University of Chicago Press;<br />

1982.<br />

2. Murnaghan JH, Talalay P. H. H.<br />

Dale’s account of the standardization of<br />

insulin. Bull Hist Med 1992; 66: 440–50.<br />

3. Banting FG, Best CH, Collip JB, et<br />

al. <strong>The</strong> effect of pancreatic extract (insulin)<br />

on normal rabbits. Am J Physiol 1922; 62:<br />

162–76.<br />

4. Sinding C. Making the unit of insulin:<br />

Standards, clinical work, and industry,<br />

1920–1925. Bull Hist Med 2002; 76: 231–70.<br />

5. Sansum WD, Blatherwick NR, Smith<br />

FH, et al. <strong>The</strong> treatment of diabetes with<br />

insulin. J Metab Res 1923; 3: 641–65.<br />

6. Miles AA. Biological standards and<br />

the measurement of therapeutic activity. Br<br />

Med Bull 1951; 7: 283–91.<br />

7. Cockburn WC. <strong>The</strong> international<br />

contribution to the standarization of biological<br />

substances. I. Biological standards<br />

and the League of Nations 1921–1946. Bio-<br />

logicals 1991; 19: 161–69.<br />

8. Knaffl-Lenz E, League of Nations<br />

Health Organisation Permanent Commission<br />

on Standardization of Sera, Serological<br />

Reactions and Biological Products.<br />

Memoranda on Cardiac Drugs, Thyroid<br />

Preparations, Ergot Preparations, Filix<br />

Mas, Suprarenal Preparations, Vitamins,<br />

Pituitary, Salvarsan, Oil of Chenopodium,<br />

Insulin. III. Health. 1928 III. 10. Geneva:<br />

Publications of the League of Nations; 1928.<br />

9. Aufricht H. Guide to League of Nations<br />

Publications: A Bibliographical Survey<br />

of the Work of the League, 1920–1947. New<br />

York: Columbia University Press; 1951.<br />

10. Lacey AH. <strong>The</strong> unit of insulin. Diabetes<br />

1967; 16: 198–200.<br />

11. Best CH, Dale HH. I. Insulin. 1. <strong>The</strong><br />

new international insulin standard and the<br />

re-definition of the existing unit in terms<br />

therof. League of Nations Q Bull Health Org<br />

1936; 5: 584–658.<br />

12. Exubera (Insulin Human [rDNA origin])<br />

Drug Information: Uses, Side Effect,<br />

Drug Interactions and Warnings at RxList.<br />

http://www.rxlist.com/exubera-drug.htm.<br />

<strong>The</strong> author’s address is:<br />

5221 Town Walk Drive<br />

Hamden, Connecticut 06518<br />

E-mail: barry.fields@yale.edu<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 33


� ������������<br />

<strong>The</strong>re in a royal box<br />

ordinary folks still as rocks<br />

posed as in a portrait<br />

decide another’s fate<br />

watching evidence passing by<br />

like shooting stars in the sky.<br />

At recess the courtroom a deserted camp.<br />

In one corner the flag hangs limp<br />

like a runner out of breath.<br />

<strong>The</strong> defendant alone, the last on earth.<br />

<strong>The</strong> clock points its moving finger<br />

distanced from slander and anger.<br />

Worry directs every thought<br />

about what legal tacks have wrought<br />

that may dissolve dreams to dust<br />

threatening future with rust.<br />

<strong>The</strong> decision, at last, is made<br />

by citizens returning in parade.<br />

His honor enters in his black gown.<br />

Suspense suppresses every sound.<br />

All wait for words cast in cement<br />

that will terminate this event.<br />

“No cause,” the verdict of the jury.<br />

Behold the plaintiff’s fury.<br />

From the defendant relief effervescent bubbles<br />

from a bottle of troubles.<br />

H. Harvey Gass, MD<br />

Dr. Gass (AΩA, University of Michigan, 1941) is retired from practice as a clinical<br />

professor of Neurosurgery at Wayne State Medical School. His address is: 6155 East<br />

Longview Drive, East Lansing, Michigan 48823. E-mail: sgass@msu.edu.<br />

Illustration by Jim M’Guinness<br />

34 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Health policy<br />

Our health care system is not broken—<br />

it’s obsolete!<br />

Jordan J. Cohen, MD<br />

<strong>The</strong> author (AΩA, Tufts University, 1978) is professor<br />

of Medicine and Public Health at George Washington<br />

University and president emeritus of the Association of<br />

American Colleges.<br />

We often hear that our health care system is “broken.”<br />

Indeed, it’s become a pat refrain among<br />

policymakers and the media. But thinking the<br />

system is “broken” implies that it can be “fixed”—patched<br />

up to make it work like it used to. That’s what would-be<br />

health care reformers seem to think when they tinker with<br />

“fixes” like expanding insurance coverage with mandates and<br />

subsidies, guaranteeing insurance despite pre-conditions,<br />

crafting pay-for-performance incentives to change provider<br />

behavior, and expanding use of electronic medical records.<br />

All of these “fixes” would undoubtedly be helpful and should<br />

be implemented without delay. But unfortunately, even in the<br />

aggregate, these and other attempts to tinker with the current<br />

system cannot get at the fundamental problems we have to<br />

solve and, hence, are a far cry from true health care reform.<br />

Why? Because our health care system is not “broken.”<br />

Rather, it’s outmoded. It’s archaic. It’s a legacy system that is<br />

simply incapable —inherently incapable—of meeting today’s<br />

health care needs, no matter how much we tinker with it.<br />

Imagine trying to fix a Model T Ford so that it could fly. You<br />

could put in a more powerful engine, take off the fenders,<br />

strap on wings, and put on a pair of aviator goggles. But you<br />

still couldn’t get the darned thing off the ground!<br />

<strong>The</strong> hand-me-down system we’ve inherited is just like that<br />

old car, the product of a bygone era that was well designed for<br />

yesteryear but is no longer serviceable. Yesteryear was when<br />

the health care system needed to deal primarily with acute,<br />

often self-limited illness and injury; when medical technologies<br />

were much more limited in scope and much less complex;<br />

when we thought “the world’s best health care system”<br />

delivered uniformly high-quality care to everyone; and when<br />

the overall cost of health care was still in the single digits as a<br />

percentage of GDP.<br />

In times like those, our country could get along quite well<br />

with autonomous doctors working solo or in small groups.<br />

And we rather liked having our doctors in total control,<br />

with all other health care professionals playing supporting<br />

roles. We could tolerate independent hospitals<br />

competing with one another for patients. We had<br />

a fee-for-service payment system that was well<br />

designed to deal with isolated episodes of<br />

illness and discrete encounters with individual<br />

providers. And paper-based<br />

medical records kept separately by<br />

each of our providers worked<br />

well enough.<br />

Today, we face an entirely different set of realities, realities<br />

that our legacy system was never designed for, and can never<br />

be retrofitted to deal with satisfactorily. Chief among them are<br />

rising costs, an increasing burden of chronic, unrelenting disease<br />

and disability, way too many medical errors, inexplicable<br />

variations in the way medicine is practiced across the country,<br />

profound lapses in quality, and wide disparities in health and<br />

health care even among those with adequate insurance.<br />

<strong>The</strong> fragmented, uncoordinated, fee-for-service conglomeration<br />

we have inherited cannot hope to cope effectively with<br />

these twenty-first-century challenges.<br />

If policymakers would shift their mental model from “broken,<br />

let’s fix it” to “obsolete, let’s redesign it,” I doubt there<br />

would be much disagreement about the features a new system<br />

should have. We’d want “units of accountability” big enough<br />

to be held responsible for delivering comprehensive, high-<br />

quality, cost-effective care to large groups of people. <strong>The</strong>se<br />

units of accountability would be required to develop systematic<br />

approaches to weeding out waste, to coordinating the care<br />

of the chronically ill, to avoiding redundant tests, to guaranteeing<br />

that preventive strategies were broadly implemented,<br />

and to fully utilizing the skills of all health care workers in<br />

high-performing teams.<br />

Moving from our dysfunctional, fragmented legacy system<br />

to an integrated, accountable system will not be easy and will<br />

not happen quickly. <strong>The</strong> barriers to achieving the fundamental<br />

transformation required are enormous. An entirely different<br />

financing scheme will be needed to release the system from<br />

the paralyzing constraints of our current fee-for-service arrangement,<br />

and a new cultural paradigm among providers will<br />

be needed to foster collaboration, teamwork, accountability,<br />

quality improvement, and patient safety. Even before clearing<br />

those barriers, however, a way must be found to overcome the<br />

resistance from entrenched stakeholders who are profiting<br />

handsomely from the current system and who have powerful<br />

political allies.<br />

But the risk of trying to preserve an obsolete system is<br />

simply too great to let these obstacles stand in the way of<br />

needed reforms. Fortunately, a window of opportunity has<br />

opened up. Buried in the myriad “fixes” included in the Patient<br />

Protection and Affordable Care Act is a call for CMS to promote<br />

demonstration projects to implement and evaluate innovative<br />

approaches to organizing and delivering health care.<br />

Such demonstrations could allow for the creation, on a large<br />

scale, of what Stephen Shortell and Lawrence Casalino have<br />

called accountable care systems, systems that are “capable of<br />

implementing organized processes for improving the quality<br />

and controlling the costs of care, and of being held accountable<br />

for the results.” 1 Being “accountable” would entail both<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 35


Our health care system is not broken—it’s obsolete!<br />

demonstrating appropriate clinical outcomes and taking on<br />

significant financial risk. It’s hard to imagine how these expectations<br />

could be met in the absence of a fully integrated system<br />

of providers in which doctors, nurses, hospitals, public health<br />

professionals, nursing homes, pharmacists, home health<br />

agencies, etc. join forces to manage cost-effectively the care of<br />

individuals and to deal systematically with the known health<br />

needs of a region or population.<br />

As possible points of departure for developing such<br />

truly accountable care systems, Shortell and Casalino suggest<br />

several current organizational arrangements including<br />

multispecialty group practices, hospital staff organizations,<br />

physician-hospital organizations, independent practice organizations,<br />

and health plan-provider organizations or networks.<br />

I’m concerned that none of these existing organizational arrangements<br />

is likely to be sufficiently scalable to meet the real<br />

challenges. What has more potential of doing so, in my view,<br />

are well-organized academic health centers.<br />

Indeed, many academic health centers are uniquely poised<br />

to develop the kind of integrated health care systems that we<br />

need. Many already have organized faculty practice plans, a<br />

network of affiliated hospitals, community physician referral<br />

bases, a relatively robust IT infrastructure, a tradition of innovation,<br />

loyal patients, and the trust and respect of their communities.<br />

Modern information technologies could be used to<br />

stitch together the network of hospitals, doctors, home health<br />

agencies, pharmacies, and other community resources needed<br />

both to provide for the health and health care needs of a large<br />

population and to monitor the system’s fiscal performance<br />

and to identify opportunities for improvement. Given their<br />

existing capabilities—and their avowed mission to serve the<br />

public interest—academic health centers, either individually<br />

or preferably in partnership with others, should lead the way<br />

toward solving what is arguably the most urgent health problem<br />

facing our county.<br />

However we do it, if we want our health care system to fly<br />

in the twenty-first century, we’ve got to stop trying to repair<br />

a hodgepodge arrangement that is hopelessly antiquated and<br />

get on with the hard work of replacing it with a real system<br />

that can actually do the job. Now that Congress has provided<br />

CMS with substantial resources to fund more appropriate<br />

ways to structure and finance health care services, I believe<br />

academic health centers—as engines of innovation—should<br />

seize the opportunity to demonstrate what true health care<br />

reform might look like.<br />

References<br />

1. Shortell SM, Casalino LP. Health care reform requires accountable<br />

care systems. JAMA 2008; 300: 95–7.<br />

Memento Mori<br />

<strong>The</strong> first one caught me by surprise.<br />

I was doing my initial thoracentesis,<br />

a task less daunting than the word implies.<br />

A cheerful woman gasped from fluid in her chest,<br />

a pleural effusion caused by rampant cancer.<br />

<strong>The</strong>re was no effusiveness in the somber needle<br />

I guided carefully through her chest wall.<br />

“I’m going to die now,” she calmly said,<br />

and, with nothing further, laid back dead.<br />

It was the moment doctors dread;<br />

full frontal with the enemy ahead<br />

And I midwife to the highest drama.<br />

This was no time for contemplation.<br />

Coding, CPR, intracardiac adrenaline;<br />

we were quick and forceful, but for naught.<br />

Relatives were notified, and in intense detail<br />

we probed each second, searching for a clue or cause.<br />

None came, and nothing from a later autopsy.<br />

We had no solution, no solace, and no one to blame.<br />

While preachers celebrate the rising soul,<br />

and mystics sense transfiguration, and<br />

loved ones clasp one another, casting<br />

hope against the loneliness of death,<br />

we found no answer in her body,<br />

no meaning in the metaphysics,<br />

and nothing in ourselves to talk about.<br />

Michael R. Milano, MD<br />

<strong>The</strong> author’s address is:<br />

1177 22nd Street, NW<br />

Jim M’Guinness<br />

Washington, DC 20037<br />

E-mail: msdjjc@gwumc.edu<br />

Dr. Milano (AΩA, Albany Medical College, 1964) is a psychiatrist living<br />

36 and practicing in Teaneck, New Jersey. <strong>The</strong> His <strong>Pharos</strong>/<strong>Winter</strong> e-mail address is: milanovino- <strong>2011</strong><br />

nos@aol.com.


Reading a Review<br />

M. Esteller. Molecular Origins of Cancer: Epigenetics in Cancer.<br />

N Engl J Med 2008; 358: 1148.<br />

I have learned from this reading that I will die<br />

not by the agency of great gods of sea and sky,<br />

or of the lesser ones, the sprites of groves and wells,<br />

nor even by will of the many-breasted mother,<br />

Earth herself.<br />

I must kneel instead to bits of my own cells,<br />

those invisible smalls within, where methyls delve,<br />

and shortened ribbons of RNA<br />

plug phosphates to genes and capriciously play<br />

with my molecules making them epigenetic.<br />

This change in belief runs through me like a panic attack.<br />

Worship my genes? <strong>The</strong>y are far too small<br />

for that. I am used to gods who are huge, and call<br />

on lightning’s power, or sometimes explode a sun<br />

over a cave in Palestine.<br />

Water from rock, pillars of fire define<br />

my life and beliefs. How can I live with the notion<br />

that these new gods of cancer, incapable of emotion,<br />

not even of guilt, have no concept of<br />

a high God’s mercy and unearthly love?<br />

Must I plead to my own, these bits of cell débris,<br />

even as they settle down to murder me?<br />

H. J. Van Peenen, MD<br />

Dr. Van Peenen is retired from medical practice. His address is: 74 W. 29th<br />

Avenue, Apartment 1103, Eugene, Oregon 97405. E-mail: lkvanp@comcast.net.<br />

Illustration by Jim M’Guinness<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 37


2010 <strong>Alpha</strong><br />

<strong>Omega</strong> <strong>Alpha</strong><br />

Robert J. Glaser<br />

Distinguished<br />

Teacher Awards<br />

Each year since 1988, <strong>Alpha</strong><br />

<strong>Omega</strong> <strong>Alpha</strong>, in cooperation<br />

with the Association of American<br />

Medical Colleges, presents four AΩA<br />

Distinguished Teacher Awards to<br />

faculty members in American medical<br />

schools. Two awards are for ac-<br />

Gary L. Dunnington, MD (Clinical)<br />

J. Roland Folse Professor and Chair of<br />

Surgery, Southern Illinois University<br />

School of Medicine<br />

Dr. Dunnington (AΩA, University<br />

of Southern California, 1994) joined<br />

Southern Illinois University School of<br />

Medicine in 1979 as professor in the<br />

Department of Surgery. Since then, he<br />

has been director of the General Surgery<br />

Residency Program and professor and<br />

chair of the Department of Surgery. He<br />

was named the J. Roland Folse Professor<br />

and Chair of Surgery in 2009.<br />

Dr. J. Kevin Dorsey, dean of the<br />

complishments in teaching the basic<br />

sciences and two are for inspired<br />

teaching in the clinical sciences.<br />

In 1997, AΩA named the award to<br />

honor its retiring executive secretary<br />

Robert J. Glaser, MD. Nominations<br />

for the award are submitted to the<br />

AAMC each spring by the deans of<br />

medical schools.<br />

Nominations were reviewed by a<br />

committee chosen by AΩA and the<br />

AAMC. This year’s committee members<br />

were: Ronald Arky, MD; David<br />

A. Asch, MD, MBA; J. John Cohen,<br />

MD, PhD; Molly Cooke, MD; Eugene<br />

C. Corbett, MD, FACP; Linda S.<br />

Costanza, PhD; Arthur F. Dailey II,<br />

PhD; Erika Goldstein, MD; Aviad<br />

Distinguished teachers Gary L. Dunnington, MD; Duane E. Haines, PhD; John W. Pelley,<br />

PhD; and James R. Stallworth, MD. Deborah E. Powell, MD, immediate past chair of<br />

the AAMC board of directors and Associate Vice President for New Models of Medical<br />

Education is on the left. On the right are Richard L. Byyny, MD, Executive Director of <strong>Alpha</strong><br />

<strong>Omega</strong> <strong>Alpha</strong>, and Darrell G. Kirch, MD, President and CEO of the AAMC.<br />

Photo credit: Richard Greenhouse Photography, Inc. Courtesy of the AAMC.<br />

SIU School of Medicine, writes: “Dr.<br />

Dunnington is a passionate advocate<br />

and practitioner of excellence in medical<br />

education. He has received nineteen<br />

teaching awards at three institutions,<br />

including the Outstanding Teacher of<br />

the Year award at SIU in 2010. With<br />

several colleagues, he developed and<br />

refined an academic incentive system<br />

that has been in use at SIU for more<br />

than ten years. Dr. Dunnington’s influence<br />

spreads far beyond the walls of<br />

SIU, however. He was one of the thought<br />

leaders involved in the ACGME’s Task<br />

Haramati, PhD; Bruce M. Koeppen,<br />

MD, PhD; Jeanette Norden, PhD;<br />

Paul L. Rogers, MD; James L.<br />

Sebastian, MD; Gabriel Virella, MD,<br />

PhD.<br />

Winners of the award receive<br />

$10,000, their schools receive<br />

$2,500, and active AΩA chapters<br />

at those schools receive $1,000.<br />

Schools nominating candidates for<br />

the award receive a plaque with the<br />

name of the nominee.<br />

Brief summaries of the accomplishments<br />

in medical education of<br />

the 2010 award recipients follow.<br />

Richard L. Byyny, MD<br />

Executive Director<br />

Force charged with developing the six<br />

competencies toward which all residencies<br />

in the United States now train. He<br />

and four other surgeons were founding<br />

members of the American College of<br />

Surgeon’s Surgeons as Educators course.<br />

He facilitated the development of a “surgery<br />

readiness” elective for senior medical<br />

students, which is among the highest<br />

rated electives in the school and has<br />

inspired other SIU clinical departments<br />

to create similar electives. <strong>The</strong> report of<br />

the program in the medical literature has<br />

spawned numerous clones. A comprehensive<br />

system for evaluating operating<br />

room performance was selected by the<br />

American Board of Surgery as a template<br />

for a national system for rating operative<br />

performance. It will be required for all<br />

applicants for board certification.”<br />

Dr. Dunnington says of teaching, “You<br />

have to teach from the learner’s agenda,<br />

not from scripts. A truly great teacher<br />

says, ‘What can I help you learn today?’ ”<br />

Duane E. Haines, PhD (Basic)<br />

Professor and Chairman, Department<br />

of Anatomy, University of Mississippi<br />

Medical Center School of Medicine<br />

Dr. Haines received his PhD in<br />

Anatomy-Physical Anthropology at<br />

Michigan State University. He joined<br />

the University of Mississippi in 1985<br />

as a professor of Anatomy. He has received<br />

the A. J. Ladman AAA/Wiley<br />

Exemplary Service Award and the Henry<br />

Gray/Elsevier Distinguished Educator<br />

Award from the American Association<br />

of Anatomists, and the Silver Hammer<br />

Award as Teacher of the Year from<br />

38 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


the Department of Neurology at the<br />

University of Mississippi Medical Center.<br />

Dr. LouAnn Woodward, dean of the<br />

University of Mississippi Medical Center<br />

School of Medicine writes of Dr. Haines:<br />

“Dr. Haines embodies the definition of<br />

“doctor” from the Latin “to teach.” He<br />

has consistently gone the extra mile to<br />

provide an excellent quality education<br />

program with a focus on clinically relevant<br />

information.<br />

“Dr. Haines is well recognized for his<br />

atlas of the human brain, Neuroanatomy:<br />

An Atlas of Structures, Sections, and<br />

Systems, now in its eighth edition. He<br />

is also the editor and co-author of<br />

Fundamental Neuroscience for Basic and<br />

Clinical Applications, currently in its<br />

third edition.<br />

“At every medical center where he<br />

has held a faculty position, Dr. Haines<br />

has been extensively involved in teaching<br />

programs of his department. His many<br />

teaching awards span both undergraduate<br />

and graduate education.<br />

“Dr. Haines is a model educator and<br />

true scholar with a great heart for students.”<br />

John W. Pelley, PhD (Basic)<br />

Associate Professor of Cell Biology<br />

and Biochemistry, Texas Tech Health<br />

Sciences Center School of Medicine<br />

Dr. Pelley received his PhD in Zoology<br />

from the University of North Carolina.<br />

He joined TTUHSC in 1972 as assistant<br />

professor in Biochemistry.<br />

Dr. Pelley has received the President’s<br />

Excellence in Teaching Award twice<br />

at TTUHSC. He has also received the<br />

School of Nursing Dean’s award for<br />

teaching pathophysiology. He has received<br />

the SGEA Medical Education<br />

Scholarship Award for the Outstanding<br />

Presentation and the Award for Merit<br />

for Applications in Healthcare Education<br />

by the International Associate for<br />

Psychological Type.<br />

Dr. Steven L. Berk, dean of the<br />

School of Medicine, writes: “Dr. Pelley<br />

has achieved significant recognition for<br />

his teaching contributions both within<br />

and outside of the TTUHSC School of<br />

Medicine due to his use of innovations in<br />

the classroom such as concept mapping,<br />

question analysis and ‘prefrontal pauses.’<br />

<strong>The</strong>se teaching strategies are designed<br />

to develop the student’s ability to learn<br />

as well as to improve delivery of content.<br />

He has authored a popular USMLE Step<br />

1 review book, now in its third edition,<br />

and a course companion biochemistry<br />

book that is part of an integrated series<br />

(second edition in preparation).<br />

“Dr. Pelley’s teaching extends well<br />

beyond biochemistry. He has developed<br />

an expertise in learning theory and strategies<br />

in medical education. He developed<br />

his metacognitive approach to learning<br />

during his ten-year tenure as associate<br />

dean for Academic Affairs, which he<br />

documented in the book SuccessTypes in<br />

Medical Education, freely available at the<br />

SuccessTypes Medical Education Page<br />

(www.ttuhsc.edu/som/success/default.<br />

htm). Dr. Pelley is an active member<br />

of the international medical education<br />

listserve, DR-ED, the Southern Group<br />

on Educational Affairs, International<br />

Association of Medical Science<br />

Educators, and Team Based Learning<br />

Collaborative.”<br />

James R. Stallworth, MD (Clinical)<br />

Associate Professor, Department<br />

of Pediatrics, University of South<br />

Carolina School of Medicine<br />

Dr. Stallworth (AΩA, University<br />

of South Carolina, 1987) joined the<br />

University of South Carolina in 1979<br />

as an instructor in Pediatrics. He is<br />

currently associate professor in the<br />

Department of Pediatrics, Vice Chair<br />

for Education and Faculty Development,<br />

the M-III Pediatrics Clerkship Director,<br />

and Director of Student Recruitment.<br />

Dr. Richard A. Hoppmann, dean of the<br />

School of Medicine, writes: “<strong>The</strong>re is<br />

only a short list of names on the outstanding<br />

teachers list at the University<br />

of South Carolina School of Medicine.<br />

<strong>The</strong> name of Dr. James Stallworth is at<br />

the top of that list. A faculty member for<br />

over thirty years, he has become a legend<br />

among students, faculty, and alumni.<br />

Dr. Stallworth’s involvement in undergraduate<br />

education spans all four years<br />

of medical school, but he is best known<br />

for his role as M-III Pediatrics Clerkship<br />

Director, a position that he has held for<br />

twenty-seven years. <strong>The</strong> reason he remains<br />

clerkship director has nothing to<br />

do with lack of ambition, but everything<br />

to do with his passion for medical education<br />

and his desire to see every student<br />

reach their full potential and succeed as<br />

a physician. Over the years he has garnered<br />

tremendous respect from students<br />

for his straightforward, no-nonsense approach<br />

to pediatric clinical education,<br />

and for the high ethical and professional<br />

standards that he sets for himself and for<br />

students.<br />

“It is because of Dr. Stallworth that<br />

many of our students over the years have<br />

chosen to train as pediatricians. Former<br />

students would tell you about his caring<br />

and concern for his patients. <strong>The</strong>y would<br />

also tell that Dr. Stallworth could be<br />

quite intimidating, but he never let any<br />

of them give any less than their best for<br />

their patients and themselves.”<br />

Distinguished teacher nominees<br />

Patricia Lipford Abbitt, MD, University of<br />

Florida College of Medicine<br />

Ezra Amsterdam, MD, University of California,<br />

Davis, School of Medicine<br />

Charles L. Bardes, MD, Weill Cornell Medical<br />

College<br />

John B. Bass, Jr., MD, University of South<br />

Alabama School of Medicine<br />

David M. Clive, MD, University of<br />

Massachusetts Medical School<br />

Joseph C. Fantone, MD, University of Michigan<br />

Medical School<br />

Mark Christian Flemmer, MD, Eastern Virginia<br />

Barbara Freeman, PhD, Case Western Reserve<br />

University School of Medicine<br />

Joshua I. Goldhaber, MD, David Geffen School<br />

of Medicine at UCLA<br />

Stephen B. Greenberg, MD, MACP, Baylor<br />

College of Medicine<br />

Richard Gunderman, MD, PhD, MPH, Indiana<br />

University School of Medicine<br />

Jesse B. Hall, MD, University of Chicago<br />

Pritzker School of Medicine<br />

Thomas Karl Hoskison, MD, University of<br />

Oklahoma College of Medicine<br />

David C. Kaufman, MD, FCCM, University of<br />

Rochester<br />

James P. Keating, MD, Washington University<br />

in St. Louis School of Medicine<br />

Gary L. Kolesari, MD, PhD, Medical College of<br />

Wisconsin<br />

Susan Lehmann, MD, Johns Hopkins University<br />

School of Medicine<br />

Ruth Levine, MD, University of Texas Medical<br />

Branch at Galveston<br />

Fred A. Lopez, MD, LSU Health Sciences<br />

Center School at of Medicine at New Orleans<br />

Salvatore Mangione, MD, Jefferson Medical<br />

College of Thomas Jefferson University<br />

Kathryn Montgomery, PhD, Northwestern<br />

University, <strong>The</strong> Feinberg School of Medicine<br />

David Muller, MD, Mount Sinai School of<br />

Medicine of New York University<br />

Dennis H. Novack, MD, Drexel University<br />

College of Medicine<br />

Mark T. O’Connell, MD, University of Miami<br />

Miller School of Medicine<br />

Noor A. Pirzada, MD, <strong>The</strong> University of Toledo<br />

College of Medicine<br />

Mark L. Savicakas, PhD, Northeastern Ohio<br />

University Colleges of Medicine and Pharmacy<br />

Maria C. Savoia, MD, University of California,<br />

San Diego, School of Medicine<br />

John S. Sergent, MD, Vanderbilt University<br />

School of Medicine<br />

Paul Shanley, MD, State University of New<br />

York Upstate Medical University College of<br />

Medicine<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 39


<strong>The</strong> Write a Poem for This Photo Contest was the brainchild of<br />

Ted Harris, who loved the intersection of images and imagery.<br />

<strong>The</strong> charming photograph illustrating the poems was taken<br />

by Dr. Anthony Shaw (AΩA, University of Virginia, 1980) of<br />

Pasadena, California.<br />

<strong>The</strong> winning poems in this year’s contest are:<br />

First prize: “Benevolent Instructions” by David R. Downs, MD.<br />

Second prize: “Commencement” by David F. Dozier, Jr., MD.<br />

Third prize: “Adolescent Choices” by H. J. Van Peenen, MD.<br />

Benevolent Instructions<br />

If I’ve told you once, I’ve told you twice<br />

It’s this way, Junior, to the ice.<br />

David R. Downs, MD<br />

Dr. Downs was elected to AΩA at the University of<br />

Wisconsin in 1957. His address is: 411 West Merrimac Street,<br />

Dodgeville, WI 53533-1409. E-mail: dbdowns@mhtc.net.<br />

40 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong><br />

W


����������������<br />

�<br />

�����������������<br />

�<br />

������������������<br />

Commencement<br />

I see him with his friend,<br />

Describing sights he’s just discovered.<br />

I feel a father’s pride<br />

As he revels in his furry youth.<br />

This is no time to tell him<br />

Of the Orca, or the sea’s<br />

Potential rage and power.<br />

I’ll keep my distance,<br />

Keep him safe by nudge<br />

And praising, and let him feel<br />

<strong>The</strong> buoyant joy of entering the water.<br />

Soon enough he’ll grow and hunt for food,<br />

And huddle with the family<br />

When the winter blizzards blast us.<br />

For now, he rules his world,<br />

But I’ll be watching.<br />

David F. Dozier, Jr., MD<br />

Dr. Dozier received his MD from Stanford University<br />

in 1961. His address is 5168 Mississippi Bar Drive,<br />

Orangevale, California 95662. E-mail: david_dozier@<br />

sbcglobal.net.<br />

Adolescent Choices<br />

Two friends are making up their minds.<br />

To stay or go? How compromise if<br />

Right wants out and Left wants stay?<br />

Which one of them for both decides?<br />

“That way,” Right points a furry wing,<br />

but Left is skeptical. He thinks<br />

Right too impulsive, immature,<br />

and leaving home so soon unwise.<br />

<strong>The</strong> next frame of the film will show<br />

them parting. Left will turn away,<br />

the good son going back to mother.<br />

(She’s at the photo’s edge, her head<br />

embroidered yellow, white, and red.)<br />

And Right the tempter, Right the other,<br />

will waddle to the right to seek<br />

whatever comes from being born<br />

with an impulsive stubborn streak.<br />

<strong>The</strong>se two age mates, once hatched together,<br />

once childhood friends and now half-grown,<br />

part frostily to grow alone<br />

into a harsh maturity.<br />

One to warm eggs on frozen feet.<br />

One be eaten by a seal.<br />

H. J. Van Peenen, MD<br />

Dr. Van Peenen’s address is 74 W. 29th Avenue,<br />

Apartment 1103, Eugene, Oregon 97405. E-mail:<br />

lkvanp@comcast.net.<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 41


<strong>The</strong> physician at the movies<br />

Peter E. Dans, MD<br />

Wall Street: Money Never Sleeps<br />

Starring Michel Douglas, Shia La Beouf, Josh Brolin, Carey<br />

Mulligan, Eli Wallach.<br />

Directed by Oliver Stone. Rated PG-13. Running time 133<br />

minutes.<br />

It’s hard to believe that the original Wall Street was released<br />

twenty-three years ago. Like <strong>The</strong> Godfather, it has achieved<br />

iconic status with its memorable Oscar-winning performance<br />

by Michael Douglas as Gordon Gekko and its signature line<br />

“Greed is good.” Gekko accumulates billions by wedding his<br />

belief that “information is the most valuable commodity” with<br />

a philosophy based on the writings of the sixth-century-BC<br />

Chinese warlord Sun Tzu. As Gekko tells his protégé Bud<br />

Fox (Charlie Sheen), “I don’t just throw darts at a board. Read<br />

Sun Tzu’s <strong>The</strong> Art of War. Every battle is won before it is ever<br />

fought.” To Gekko, the game is “not about the money; it’s<br />

about the game between people.” In short, it’s about winning,<br />

or in the words of a popular phrase of the time, “the one<br />

who dies with the most toys wins.”<br />

Not surprisingly, the sales of <strong>The</strong> Art of War,<br />

which is still used in war colleges, skyrocketed after<br />

the film as Gekko wannabes tried to absorb<br />

some of its lessons. In the original movie,<br />

Shia La Beouf in Wall Street: Money Never Sleeps.<br />

20th Century-Fox/Photofest<br />

Gekko is brought down by Fox who, after he is caught doing<br />

insider trading, saves his hide by wearing a wire to incriminate<br />

Gekko. Before being sent to prison, Gekko sequesters $100<br />

million in a Swiss account in his children’s names.<br />

<strong>The</strong> sequel begins in October 2001 at Sing Sing, where<br />

Gekko is released after having served his eight-year sentence<br />

for insider trading and securities fraud. He reclaims his possessions,<br />

including an out-of-date cell phone and, when no<br />

one is there to meet him, he takes a cab back to “the city.” <strong>The</strong><br />

scene shifts to 2008 with two Gen Xers in bed as the morning<br />

news comes on the television. <strong>The</strong> woman is Gekko’s estranged<br />

daughter Winnie, who angrily shuts off the TV upon<br />

hearing that Gekko is back in the limelight promoting his<br />

book Is Greed Good? Winnie used to visit her father regularly<br />

in prison until her brother died of a drug overdose that she<br />

blamed on her father. As seeming recompense for Gordon’s<br />

sins, she has become a blogger for an anti-corporate website,<br />

Frozen Truth. Her live-in boyfriend, Jake Moore (Shia La<br />

Beouf), insists that she ought to hear about him, but she wants<br />

none of it. Jake, it turns out, is an up-and-coming Wall Street<br />

trader whose “saving grace” is his championing of alternative<br />

energy technology to save the planet. He is employed by the<br />

firm Keller/Zabel (KZI), headed by a one-time powerful figure<br />

Louis Zabel (Frank Langella), to whom Jake is devoted. Zabel<br />

42 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


dodges Jake’s questions about rumors that KZI is on the brink<br />

of insolvency, saying, “Are we going under? That’s the wrong<br />

question. Who isn’t?” He ends the conversation by giving Jake<br />

a $1.45 million bonus, telling him to enjoy it. Jake uses part<br />

of it to buy Winnie an engagement ring (although he knows<br />

she’s against marriage) and to go out partying. He decides to<br />

plow the rest into KZI despite a friend’s warning that the firm,<br />

having kept subprime mortgage toxic debt off its books, is in<br />

danger of collapse.<br />

Enter Bretton James (Josh Brolin), the CEO of Churchill<br />

Schwartz, a fictional firm meant to represent a combination<br />

of Goldman Sachs and J.P. Morgan. By refusing to support a<br />

bailout for KZI, he engineers its destruction as a payback for<br />

Zabel’s not bailing out Churchill Schwartz eight years before<br />

under similar circumstances. <strong>The</strong>re are ominous meetings of<br />

the Federal Reserve Commission in New York as Zabel unsuccessfully<br />

tries to trade on old loyalties and friendships by<br />

pleading his case before the group that holds his fate in their<br />

hands. <strong>The</strong>re are a couple of great scenes on the Upper West<br />

Side in Central Park and the subway, involving a distraught<br />

Zabel and Jake.<br />

Re-enter Gekko as he goes on the lecture circuit to Fordham<br />

Business School to publicize his book. He tells the students<br />

that “money is a bitch that never sleeps and she is jealous.” He<br />

reiterates his old axiom that greed is good, but too much is<br />

not, and that greed is legal. He notes that forty percent of the<br />

nation’s profits come from financial services, not production<br />

of goods, principally involving what he calls “banks on steroids.”<br />

Jake goes up to him after the lecture and tells him that<br />

he is engaged to Winnie. <strong>The</strong>y ride the subway together and<br />

forge a quid pro quo arrangement in which Gekko helps Jake<br />

unravel the steps leading to the destruction of KZI in return<br />

for trying to reconcile him with his daughter. This grafting<br />

of a love affair, such as it is, onto the picture’s main theme of<br />

the convoluted machinations of the Wall Street traders never<br />

really works. It seems like an attempt to reach a younger audience<br />

while showing that Gekko has some humanity (although<br />

not much). He is not averse to duping his daughter and Jake<br />

to get back his $100 million, which he promptly turns into $1<br />

billion, showing that he hasn’t lost his old touch.<br />

<strong>The</strong> film is filled with what might be called “inside baseball,”<br />

with references to the cutthroat side of the financial<br />

world with its own arcane language of credit default swaps,<br />

hedge funds, derivatives, bundling subprime mortgages, and<br />

toxic debt. At the time, these terms were totally unfamiliar to<br />

the majority of the public whose retirement funding depended<br />

on their effects on the markets. <strong>The</strong>y were also ignored by the<br />

numerous public watchdogs at the Federal Reserve, the relevant<br />

Congressional committees, and the SEC until the crisis<br />

exploded into public consciousness in 2008. <strong>The</strong>re are also<br />

the references to banks being “too big to fail” and their being<br />

given bailouts in which they are awarded 100 cents on the<br />

dollar while investors are short-changed. This illustrates the<br />

concept of “moral hazard”—someone takes your money and<br />

acts differently when insulated from risks than he would if he<br />

were fully responsible for losses. <strong>The</strong> comment in the film is<br />

that it is “unethical but not illegal.”<br />

Though long, the film held my interest throughout. What<br />

is particularly good about it is the acting, first by Douglas<br />

who looks as old, tired, and sick as he is in real life. Look for<br />

another Best Actor Oscar, possibly posthumously. Next is the<br />

outstanding supporting cast. Frank Langella is great as an old<br />

Lion being eaten alive by the unscrupulous young shark played<br />

by Josh Brolin. Eli Wallach is also great as Jules Steinhardt, another<br />

old Lion, who looks half-dead but is still in control, just<br />

as he was in <strong>The</strong> Godfather until he got bumped off by that<br />

cannoli. As he drops his little pearls, he emits a little whistle,<br />

one of the best touches in the film that I have to believe he improvised.<br />

Susan Sarandon is less effective as Jake’s mother, who<br />

is forever cadging money from her son for failed real estate<br />

schemes. Also look for Oliver Stone, who pulled a Hitchcock<br />

by appearing in both films as a trader. <strong>The</strong>re are many shots<br />

of New York’s buildings and a little taste of sex, drugs, and<br />

materialistic excess as the young lions get outrageous bonuses.<br />

Oliver Stone is one of my bête noirs. His outlandish attempts<br />

to rewrite history, his admiration for Castro and Chavez, and<br />

his inane pronouncements characterizing Hitler as simply a<br />

“product of his time” and extolling the “good” side of Stalin,<br />

have discredited him in my view. Still, I must commend him<br />

for clearly being ahead of the curve with these two films.<br />

He was filming the first one in 1985 and released it in 1987,<br />

when the financial crash occurred. As for the second, he was<br />

promptly on the case of the 2008 debacle in that the film began<br />

shooting that year. He also has highlighted the fact that<br />

wealth in America was once based on the production of goods.<br />

That has changed in the computer age, when information<br />

can make or break individuals and companies and paper has<br />

replaced tangible goods as the currency of wealth. He presumably<br />

learned that lesson from his father, who was a broker at<br />

Shearson Lehman into the 1980s. Maybe he should give up<br />

making pictures and be “the canary in the coal mine” in the<br />

corner at those federal watchdog group meetings.<br />

Conviction<br />

Starring Hilary Swank, Sam Rockwell, Minnie Driver, Juliette<br />

Lewis and Peter Gallagher.<br />

Directed by Tony Goldwyn. Rated R. Running time 107 minutes.<br />

I<br />

’m conflicted about Conviction. I attended a screening with<br />

a friend and if I had driven my own car, I would have been<br />

gone after the first fifteen minutes. If I had been watching it<br />

at home, I certainly would have gonged it. Here’s why. <strong>The</strong><br />

film opens in 1980 with a long handheld camera sequence<br />

panning over a grisly, blood-soaked murder scene in Ayer,<br />

Massachusetts, where a woman named Katharina Brow had<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 43


<strong>The</strong> physician at the movies<br />

been stabbed over thirty times. This is followed by rapid<br />

clips of two children, Kenny and Betty Anne Waters, stealing<br />

from and trashing the lady’s house, getting punished by their<br />

mother who gave birth to nine children by seven fathers, and<br />

being sent to foster homes, intercut with scenes of them as<br />

adults. Kenny (Sam Rockwell) is clearly a certifiable sociopath,<br />

alternating between turning on the charm and acting out his<br />

violent temper. He is repeatedly taken into custody by policemen<br />

who profess to like him and excuse his behavior. <strong>The</strong><br />

scene that really turned me off was where he is in a bar dancing<br />

with his little child in his arms at a family celebration. A<br />

person he accidentally knocks into questions his taking such<br />

a toddler into a bar and at that time of night. Kenny slowly<br />

puts his child down and goes over and punches out the guy’s<br />

lights. <strong>The</strong>n he turns on the charm by buying everyone a drink<br />

and does a full striptease to the amusement of his family and<br />

the patrons. I found this scene hard to believe as well as to<br />

stomach.<br />

After the woman is killed, Kenny is confronted by the police<br />

and detective Nancy Taylor (Melissa Leo) while sawing<br />

wood at his home next door to the murder scene. He fights<br />

being arrested and although he has an alibi, Taylor, whom he<br />

taunts, is seemingly out to get him. Two years later during the<br />

funeral for his grandfather in a Catholic Church, the police<br />

march down the aisle and interrupt the service to haul him off<br />

to jail in handcuffs. I’ve lived in Massachusetts and that just<br />

wouldn’t happen. I realize that this is a movie where the story<br />

is fictionalized, but this whole setup is ludicrous.<br />

I hung in for the rest of the story, which was fairly predictable<br />

but did raise some interesting issues. Kenny is brought<br />

to trial; the evidence consists of his having blood type O, the<br />

same as the perpetrator, and testimony that he had indeed<br />

been the killer by two ex-girl friends, one of whom he was<br />

living with at the time and with whom he had had a child. In<br />

1983, he is sentenced to life without parole. His sister Betty<br />

Anne (Hilary Swank) is sure he is innocent and devotes her life<br />

to exonerating him. A high school dropout, she gets her GED,<br />

a bachelor’s degree, and a law degree from Roger Williams<br />

Law School. With the help of law school classmate Abra Rice<br />

(Minnie Driver) and Barry Scheck (Peter Gallagher), cofounder<br />

of the Innocence Project, she uses DNA evidence to<br />

exonerate Kenny in 2001 after eighteen years of incarceration.<br />

During this period her devoted husband leaves her because<br />

of her obsession on behalf of her brother and all the time<br />

that her studies take away from the family. Her two children<br />

receive little attention, given her time at school and work as<br />

a waitress in a bar. <strong>The</strong> children ask to live with their father,<br />

although they appear to come back to her when he remarries.<br />

It’s particularly interesting that all the publicity and reviews<br />

refer to her doing this as a “single mom,” but she certainly<br />

didn’t start out that way.<br />

<strong>The</strong> film ends when Kenny is freed and reunited with his<br />

daughter, who had been estranged from him presumably<br />

because his weekly letters were intercepted by her mother<br />

and she believed that he was the killer. <strong>The</strong> filmmakers don’t<br />

mention that Kenny died six months after his release. <strong>The</strong><br />

few write-ups that do mention his death say only that he died<br />

“tragically,” without giving the details. Actually, he died scaling<br />

a fifteen-foot fence taking a shortcut to a convenience<br />

store. He fell on his head and was later found dead. In 2009,<br />

the town of Ayer settled his estate’s civil rights suit for $3.4<br />

million.<br />

In addition to those cited earlier, there were other problems<br />

with this movie. First of all, I was puzzled by how little attention<br />

was paid to developing Taylor’s character to gain insights<br />

into her willingness to frame Kenny as well as at least one<br />

other person. <strong>The</strong> only reason posed is that it was tough being<br />

a female detective in those days. Really! Does that justify<br />

framing people? Would they have us believe that women who<br />

pioneered in those positions had to do that to gain awards?<br />

That’s an insult to them. In addition, she seemed to have suffered<br />

no consequences beyond being given a desk job.<br />

I was also struck by the lack of attention to solving the<br />

murder. <strong>The</strong> police spent two fruitless years investigating a<br />

murder that cried out for seeking someone who knew the<br />

victim and hated her with a passion. Given all the evidence<br />

at the crime scene, consisting of fingerprints, hair, and blood,<br />

they dawdled before nailing the wrong guy. <strong>The</strong>re was also<br />

no mention of using the DNA database even though it was<br />

operational years later. <strong>The</strong> emphasis was on exoneration, not<br />

solving the murder. Not only that, but the producers never<br />

met with the victim’s children to tell them of the movie, which<br />

justly troubled them, another example of how negligent they<br />

were in touching base with the principals in the case except<br />

for Betty Anne Waters.<br />

Okay, what are the redeeming features? First, the acting.<br />

Hilary Swank, who is in almost every scene, although she<br />

never seems to age, gives an earnest if unexceptional performance.<br />

Still, I predict she will earn an Oscar nomination in<br />

this year’s Erin Brockovich secular saint category. Much better<br />

is Juliette Lewis in a small role as Roseanna Perry, a reclusive<br />

alcoholic girlfriend with rotten teeth and a loopy demeanor<br />

who is persuaded by Taylor to testify that Kenny was the killer.<br />

Interestingly, Lewis never met the actual person she plays and<br />

a blogger who knew the woman said neither she nor her teeth<br />

were anything like what was portrayed in the film, although<br />

Kenny did knock out two teeth which she got replaced.<br />

Getting the story right seems to take a back seat to an Oscar<br />

nominating performance. By contrast, Sam Rockwell gives a<br />

riveting pull-out-all-the-stops performance that doesn’t sugarcoat<br />

Kenny. He should win the Academy award for Best Actor,<br />

given that the Academy loves anti-heroes, especially those that<br />

are somewhat depraved. Rockwell drew from his hardscrabble<br />

youth as a rebel in a home broken by divorce when he was<br />

five and as someone who committed petty crimes, to create<br />

a character who alternates between Dr. Jekyll and Mr. Hyde.<br />

44 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Hilary Swank and Sam Rockwell in Conviction. Photo by Ron Batzdorf.<br />

<strong>The</strong> film also shows how misleading evidence based on<br />

blood typing was in the days before DNA testing was available.<br />

<strong>The</strong> film credits Barry Schenk and the Innocence Project<br />

he co-founded in 1992 at Cardozo School of Law of Yeshiva<br />

University in 1992 for providing the guidance that got Kenny<br />

off. <strong>The</strong>y receive thousands of requests per year and have been<br />

able to use DNA evidence, as of November 2, 2010, to exonerate<br />

261 convicted felons, some of whom had been on death<br />

row. This figure is impressive, and I couldn’t help but marvel<br />

at the fact that DNA evidence could be exculpatory but in the<br />

case of O.J. Simpson insufficient to obtain his conviction, in<br />

part because DNA testing was impugned by the defense.<br />

Finally, there is an interesting sidebar involving Martha<br />

Coakley, the attorney general of Massachusetts who lost the<br />

senatorial contest to Scott Brown in 2010. She is portrayed as<br />

a villain because she was presumably the Middlesex County<br />

District Attorney (DA) when Taylor framed Kenny, and who<br />

gave Taylor an award. She’s also shown stonewalling the performance<br />

of the DNA testing and then refusing to act on the<br />

results when the DNA evidence exonerated him. Actually,<br />

she didn’t become the Middlesex County DA until 1998.<br />

Furthermore, her office not only facilitated the testing and<br />

a second test to corroborate it but she moved to vacate the<br />

conviction three days after receiving the test results and he<br />

was freed within two weeks. After a screening, she graciously<br />

complimented Swank and ascribed the misrepresentation<br />

to the need to telescope events in movies. She cheerfully<br />

lamented that it hadn’t been a good year for her. 2 It’s hard<br />

to understand the motives of the director and screenwriter.<br />

I am not a litigious person but I would sue for defamation of<br />

character, especially since the film opened two weeks before<br />

she stood for re-election as Massachusetts Attorney General.<br />

References<br />

1. <strong>The</strong> Innocence Project—About Us: Mission Statement. www.<br />

innocenceproject.org/about/Mission-Statement.php.<br />

2. Gelzinis P. Martha Coakley: Movie’s “inaccurate” but a<br />

“delight.” news.bostonherald.com/news/columnists/view.<br />

bg?articleid=1288682.<br />

Dr. Dans (AΩA, Columbia University College of Physicians and<br />

Surgeons, 1960) is a member of <strong>The</strong> <strong>Pharos</strong>’s editorial board and<br />

has been its film critic since 1990. His address is:<br />

11 Hickory Hill Road<br />

Cockeysville, Maryland 21030<br />

E-mail: pdans@comcast.net<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 45


Reviews and reflections<br />

David A. Bennahum, MD, and Jack Coulehan, MD, Book Review Editors<br />

<strong>The</strong> Checklist Manifesto: How<br />

To Get Things Right<br />

Atul Gawande<br />

New York, Metropolitan Books, 2009<br />

Reviewed by David A. Bennahum,<br />

MD (AΩA, University of New Mexico,<br />

1984)<br />

In <strong>The</strong> Checklist Manifesto, his latest<br />

lucid and elegantly written analysis<br />

of how to improve health care, Atul<br />

Gawande addresses the idea that the<br />

simple introduction of checklists to patient<br />

care can reduce costs and save<br />

lives. In each of his books and essays<br />

Gawande has engaged the reader’s interest<br />

with stories that illustrate specific<br />

points and problems. Here he begins<br />

with a surgical case that had been<br />

recounted to him by a physician<br />

colleague about a patient who<br />

had almost exsanguinated<br />

from an abdominal stab<br />

wound so deep it had<br />

cut the aorta.<br />

<strong>The</strong>re are a thousand ways that<br />

things can go wrong when you’ve<br />

got a patient with a stab wound. But<br />

everyone involved got almost every<br />

step right—the head-to-toe examination,<br />

the careful tracking of the<br />

patient’s blood pressure and pulse<br />

and rate of breathing, the monitoring<br />

of his consciousness, the fluids<br />

run in by IV, the call to the blood<br />

bank to have blood ready, the placement<br />

of a urinary catheter to make<br />

sure his urine was running clear,<br />

everything. Except no one remembered<br />

to ask the patient or the emergency<br />

medical technicians what the<br />

weapon was.<br />

“Your mind doesn’t think of a<br />

bayonet in San Francisco,” John<br />

could only say. p3<br />

<strong>The</strong> staff knew that the patient had<br />

been stabbed, but he was comfortable<br />

and talking so no one thought to ask<br />

with what and then consider the possible<br />

consequences of a deep stab wound.<br />

In the second case, a patient undergoing<br />

surgery to remove a cancer of the<br />

stomach suddenly went into cardiac<br />

arrest. Because the patient had a low<br />

potassium before surgery the anesthesiologist<br />

had given him corrective dose of<br />

potassium. Gawande in his understated<br />

but dramatic style quotes the surgeon.<br />

I was chagrined at having missed<br />

this. An abnormal level of potassium<br />

is a classic cause of asystole.<br />

It’s mentioned in every textbook.<br />

I couldn’t believe I overlooked it.<br />

Severely low potassium levels can<br />

stop the heart, in which case a cor-<br />

rective dose of potassium is the remedy.<br />

And too much potassium can<br />

stop the heart, as well—that’s how<br />

the states execute prisoners.<br />

<strong>The</strong> senior anesthesiologist<br />

asked to see the potassium bag that<br />

had been hanging. Someone fished<br />

it out of the trash and that was when<br />

they figured it out. <strong>The</strong> anesthesiologist<br />

had used the wrong concentration<br />

of potassium, a concentration<br />

one hundred times higher than he’d<br />

intended. He had, in other words,<br />

given the patient a lethal dose of<br />

potassium. p6<br />

<strong>The</strong> patient was lucky and survived,<br />

but Gawande uses these stories to argue<br />

for a simple method to prevent such<br />

errors, a checklist. In the first chapter<br />

he writes about problems of extreme<br />

complexity and how training and practice<br />

can achieve astonishing results;<br />

but he argues that in medicine we expect<br />

miracles such as that offered by<br />

penicillin. We have lost the discipline<br />

that a methodical approach requires.<br />

More than 50 million operations are<br />

performed annually in the United States<br />

and Americans undergo an average of<br />

seven operations in a lifetime. Yet we<br />

suffer 150,000 post-surgical deaths each<br />

year. Gawande writes:<br />

Moreover, research has consistently<br />

showed that at least half our deaths<br />

and major complications are avoidable.<br />

<strong>The</strong> knowledge exists. But<br />

however supremely specialized and<br />

trained we may have become, steps<br />

are still missed. Mistakes are still<br />

made. p31<br />

46 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


To better understand this idea<br />

Gawande turns to the introduction<br />

of checklists in 1935 by the U.S. Army<br />

Aircorps when it was flight-testing the<br />

aircraft that would become the B17<br />

bomber, the famous Flying Fortress.<br />

After a number of flight failures the<br />

aeronautical engineers realized that the<br />

complexity of the modern airplane required<br />

not better test pilots but rather<br />

a simple method to prevent mistakes,<br />

the checklist. He follows this by reminding<br />

the reader of the four vital signs to<br />

which a fifth sign, pain, has recently<br />

been added and asks whether these are<br />

not checklists that guide nurses.<br />

Gawande recounts the remarkable<br />

experience of Dr. Peter Pronovost at<br />

Johns Hopkins in 2001. Provonost identified<br />

five steps that a physician must<br />

take to place a central line and then<br />

asked the nurses to observe whether<br />

every physician unfailingly followed<br />

each step. In more than a third of the<br />

patients, doctors skipped at least one.<br />

Pronovost then persuaded the hospital<br />

administration to allow the nurses to<br />

stop any physician who had skipped a<br />

step. Over the next year “the ten-day<br />

line-infection rate went from 11 percent<br />

to zero.” p38 Only two line infections<br />

occurred over the next fifteen months!<br />

Pronovost had proven that checklists<br />

raised baseline performance.<br />

Gawande then goes on to explore the<br />

use of checklists in several industries<br />

and the literature on complexity. He<br />

reports that researchers have defined<br />

three categories of problems: simple,<br />

such as baking a cake; complicated,<br />

such as sending a rocket to the moon;<br />

and complex, such as raising a child. He<br />

notes the evidence in favor of checklists<br />

for simple and complicated problems,<br />

then asks whether checklists are also<br />

helpful in situations of great complexity.<br />

To address that question he cites<br />

data from the building industry about<br />

the construction of massive skyscrapers.<br />

And there again he found checklists<br />

at every level and “an annual avoidable<br />

failure rate of less than 0.00002 percent.”<br />

p71<br />

Gawande finds that checklists “are<br />

not comprehensive how-to guides,<br />

whether for building a skyscraper or<br />

getting a plane out of trouble. <strong>The</strong>y<br />

are quick and simple tools aimed to<br />

buttress the skills of expert professionals.”<br />

p128 He writes that on January 14,<br />

2009 the World Health Organization<br />

came out with a “Safe Surgery” checklist.<br />

<strong>The</strong> very next day Captain Chesley<br />

B. Sullenberger III saved U.S. Airways<br />

Flight 1549 after a flock of Canada geese<br />

flew into and stalled his aircraft’s engines.<br />

While the cool demeanor, good<br />

judgment, and experience of the pilots<br />

and crew were crucial, no less so were<br />

the years of attention to detail and the<br />

relentless discipline of their aviation<br />

checklists.<br />

This is a marvelous and elegant<br />

book. It is an important if very simple—<br />

but not simplistic—contribution to the<br />

medical literature, as is almost everything<br />

that Gawande writes. While most<br />

of the book focuses on the application<br />

of checklists to technical practice, there<br />

is one point that I found very appealing.<br />

Gawande describes that as a surgeon<br />

introducing the checklist to his own<br />

surgical teams he now asks that they<br />

begin each operation by reintroducing<br />

themselves to each other, thereby leveling<br />

the distinctions between physicians,<br />

nurses, and technicians and creating<br />

a team of the moment for the benefit<br />

of the patient. Captain Sullenberger<br />

pointed out that he and his crew were<br />

also a team, each equally important to<br />

the final outcome. At the core of <strong>The</strong><br />

Checklist Manifesto is a plea for an ethic<br />

of relationship between individuals who<br />

work together on any project and especially<br />

for those with a commitment to<br />

excellent patient care.<br />

Dr. Bennahum is a book review editor for<br />

<strong>The</strong> <strong>Pharos</strong> and a member of its editorial<br />

board. He is emeritus professor of Internal<br />

Medicine at the University of New Mexico<br />

School of Medicine. His address is:<br />

1707 Notre Dame Drive NE<br />

Albuquerque, New Mexico 87106<br />

E-mail: dbennahum@salud.unm.edu<br />

<strong>The</strong> Jump Artist<br />

Austin Ratner<br />

New York, Bellevue Literary Press, 2009<br />

Reviewed by Jeffrey L. Ponsky,<br />

MD (AΩA, Case Western Reserve<br />

University, 1971)<br />

I n the tradition of Chekhov, Somerset<br />

Maugham, and William Carlos<br />

Williams comes another MD who writes<br />

beautiful and compelling literary fiction.<br />

Austin Ratner, a graduate of Johns<br />

Hopkins Medical School, turned to fiction<br />

as a career after receiving his MD.<br />

His debut novel, <strong>The</strong> Jump Artist is a<br />

worthy addition to the ranks of literary<br />

historical fiction.<br />

<strong>The</strong> history that forms the basis for<br />

the novel is fascinating and largely unknown.<br />

Philippe Halsman was a young<br />

Latvian Jew hiking with his father in<br />

the Tyrolean Alps when his father<br />

fell to his death while walking behind<br />

Philippe on the hiking path. In an affair<br />

dubbed in Europe “<strong>The</strong> Austrian<br />

Dreyfuss Affair,” Philippe was arrested<br />

and convicted of his father’s murder<br />

and imprisoned in an Austrian jail for<br />

two years, despite only circumstantial<br />

evidence. <strong>The</strong> young, still adolescent<br />

Halsman was thrown into a world of<br />

horror and only released by a pardon,<br />

not an exoneration, after the tireless<br />

efforts of his sister Liouba and the assistance<br />

of human rights activists all<br />

over the world, including such notables<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 47


Reviews and reflections<br />

as Albert Einstein, Thomas Mann, and<br />

Eleanor Roosevelt. After being released<br />

from prison, the young Halsman was<br />

expelled from Austria permanently and<br />

went to Paris, to try fulfill his father’s<br />

dream for him of becoming an engineer<br />

or doctor. After much struggle, Philippe<br />

became a well-known Parisian photographer,<br />

only to flee Paris as the Nazis invaded.<br />

Penniless and stateless, Philippe<br />

emigrated to the United States and rose<br />

to become one of the country’s most<br />

celebrated photographers of the 1950s<br />

and 1960s. His name may be unfamiliar,<br />

but his work we all know: the famous<br />

headshot of Albert Einstein, Marilyn<br />

Monroe in a white dress backed into a<br />

corner, Salvador Dali with the curling<br />

moustache, the Duke and Duchess of<br />

Windsor jumping in the air. Halsman<br />

had more Life magazine covers to his<br />

credit than any photographer in history.<br />

<strong>The</strong> story of <strong>The</strong> Jump Artist is<br />

compelling as an arc from despair to<br />

triumph, but it is not in the straightforward<br />

telling of the story that this strong<br />

debut novel succeeds. Rather, Ratner<br />

writes the inner life of a human being<br />

who has experienced a level of trauma<br />

beyond imagination. His vivid descriptions<br />

of prison, of helplessness, and of<br />

the unearned, but agonizingly felt, guilt<br />

of a victim and survivor are so richly<br />

imagined that the reader feels that he<br />

comes to know the interior Halsman.<br />

We feel his adolescent struggles with<br />

a father whom he loved and venerated<br />

but was irritated by, his haunting sense<br />

of loss, his shocked passivity in the face<br />

of victimization, and his self-loathing,<br />

so common in victims of trauma. As<br />

he tries to make sense of his surreal<br />

experience, he moves to art just as the<br />

surrealist movement is gaining sway in<br />

Europe, and his use of the camera begins<br />

to move him into the outside world.<br />

<strong>The</strong> camera captures the full range of<br />

human emotion, from the surreal to<br />

the playful to the beautiful. As Halsman<br />

slowly allows love and art into his life,<br />

he reclaims his life. Ratner’s use of language<br />

and his strong artistic storytelling<br />

draws the reader deep into Halsman’s<br />

world and, as the novel builds, we root<br />

for his success, hoping he will overcome<br />

the tragedy of his youth. It is not just the<br />

story that stays with you, it is Halsman<br />

the human being.<br />

As physicians we are always struggling<br />

to understand the human condition.<br />

This stunning novel does what all<br />

truly fine novels should do. It illuminates<br />

an understanding of the human<br />

condition through its moving exploration<br />

of trauma, suffering, and redemption.<br />

Dr. Ponsky is the Oliver H. Payne Professor<br />

and chairman of the Department of<br />

Surgery at Case Western Reserve University<br />

and the Surgeon-in-Chief of University<br />

Hospital at Case Medical Center in Cleveland.<br />

His address is:<br />

University Hospitals, Case Medical<br />

Center<br />

Department of Surgery<br />

11100 Euclid Avenue, LKS-5047<br />

Cleveland, Ohio 44106<br />

E-mail: jeffrey.ponsky@uhhospitals.org<br />

Henry Kaplan and the Story of<br />

Hodgkin’s Disease<br />

Charlotte De Croes Jacobs<br />

Stanford, California, Stanford University<br />

Press, 2010<br />

Reviewed by William M. Rogoway,<br />

MD<br />

<strong>The</strong> 1960s and early ’70s were times<br />

of significant change in the approach<br />

to cancer therapy in this country.<br />

As the hazards and potential benefits of<br />

radiation therapy became more widely<br />

appreciated, it became a powerful treatment<br />

tool. At the same time, drugs were<br />

developed that not only led to tumor<br />

shrinkage, but, in the case of childhood<br />

leukemia, could eradicate disease.<br />

Henry Kaplan was a towering figure in<br />

this heady time of oncologic creativity.<br />

Charlotte Jacobs traces Kaplan’s beginnings<br />

in Chicago as the older son<br />

of Russian immigrants, recounting the<br />

early death of his father and his determined<br />

mother’s struggles to keep the<br />

family afloat financially and to further<br />

her favorite child’s ambitious goals. This<br />

story is interwoven with the history of<br />

the gradual recognition of Hodgkin’s<br />

disease as an entity, from Thomas<br />

Hodgkin’s original cases to Dorothy<br />

Reed’s defining pathologic description,<br />

as well as the development of radiation<br />

therapy from a scientific curiosity to a<br />

therapeutic tool. By the time Dr. Kaplan<br />

graduated from Rush Medical College<br />

in 1941, a rudimentary understanding<br />

of the disease with which he became so<br />

identified existed and radiotherapy had<br />

been used as treatment.<br />

Dr. Jacobs outlines Henry Kaplan’s<br />

rapid professional trajectory from<br />

trainee to chairman of Radiology at<br />

Stanford Medical School at age twentynine;<br />

the remainder of the book is devoted<br />

to his diverse and impressive<br />

scientific and personal achievements.<br />

<strong>The</strong> over-riding theme is that of a brilliant<br />

physician driven to ever-more ambitious<br />

goals.<br />

Where does one begin? <strong>The</strong> Stanford<br />

linear accelerator that permitted higher<br />

energy and more targeted x-ray therapy,<br />

the willingness to deliver higher doses<br />

of radiation to wider fields in the quest<br />

for Hodgkin’s disease cure, the identification<br />

of the mouse leukemia virus and<br />

the search for a human viral etiology for<br />

malignancy, attempts to create antibodies<br />

to human tumors. Kaplan gained<br />

48 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


credit for all these, sometimes leaving<br />

the contributions other investigators<br />

played in these advances forgotten or<br />

little noted. While he played a pivotal<br />

role in the clinical development of the<br />

accelerator and aggressively pushed its<br />

use forward, other clinicians at other<br />

centers were moving in the same direction.<br />

Dose escalation and contiguous<br />

uninvolved field therapy built heavily on<br />

the work of the Canadian Vera Peters,<br />

and an understanding of the logical<br />

pattern of Hodgkin’s disease spread was<br />

very much a product of his colleague<br />

Saul Rosenberg. Kaplan never did identify<br />

the elusive human tumor virus and<br />

monoclonal antibody success was left<br />

to others.<br />

Kaplan’s lasting scientific achievement<br />

was the rigorous investigation of<br />

Hodgkin’s disease. He and his associates<br />

pioneered the randomized clinical trial,<br />

answering one question and proceeding<br />

to the next in single institution studies<br />

with the single-minded goal of curing<br />

the disease and lessening the complications<br />

of therapy.<br />

Concurrent with his science, HSK, as<br />

his associates knew him, attempted to<br />

reshape Stanford’s medical school in his<br />

image. From the time he became chairman<br />

of Radiology, he assumed a leadership<br />

role in creating a research-oriented<br />

school as the university moved its medical<br />

school campus from San Francisco<br />

to Palo Alto. He was instrumental in recruiting<br />

a sterling faculty that included<br />

three future Nobel Laureates. As his<br />

department grew, he envisioned a nationally<br />

sanctioned comprehensive cancer<br />

center, but as his dream threatened<br />

to dominate the school, close colleagues<br />

withdrew support and the center never<br />

happened. This was a devastating and<br />

embittering defeat. His struggles, sometimes<br />

very contentious, with deans and<br />

other faculty were legendary, his failures<br />

and successes are carefully chronicled.<br />

<strong>The</strong>re were forays as well in the national<br />

scientific scene and HSK played<br />

a key role in refining the 1971 National<br />

Cancer Act that paved the way for a<br />

dramatic increase in funding for cancer<br />

research and NCI independence.<br />

Throughout his career, HSK developed<br />

a few close professional and<br />

personal relationships. <strong>The</strong>se were significant<br />

scientists whose common characteristic<br />

seemed to be the same drive,<br />

ambition, and dismissiveness toward<br />

others less forceful. Perhaps most interesting<br />

is the thorough account of his<br />

evolving friendship with Dr. Vincent<br />

DeVita, who was key in developing curative<br />

combination drug therapy for<br />

Hodgkin’s disease that rivaled Stanford’s<br />

radiotherapy efforts and who ultimately<br />

became the director of the National<br />

Cancer Institute. In interviewing over<br />

one hundred of his colleagues, patients,<br />

friends, and family members, Dr. Jacobs<br />

was able to bring detail to HSK’s fascinating<br />

and multifaceted life and his<br />

impact on others. Particularly revealing<br />

are first-person recollections of confrontations<br />

with associates and friends<br />

whose views differed from his. His<br />

close, though imperfect, relationship<br />

with his children is tenderly presented.<br />

Dr. Jacobs has authored a loving account<br />

of a powerful figure. While the<br />

chronology is painstaking, I’m not sure<br />

that one comes away with a balanced<br />

picture of this giant of American medicine.<br />

As Dr. Jacobs writes toward the<br />

end of her book, “anonymity wasn’t<br />

Henry’s way. If you had the chance to<br />

reach your goal, you grabbed it.” p310 He<br />

began poor with a very visible physical<br />

deformity, a brilliant mind and a desire<br />

to achieve. He worked tirelessly and<br />

with tremendous self-assurance built<br />

a scientific career that was outstanding.<br />

While not detailed in the book, at<br />

a time when radiation oncology was a<br />

relatively new discipline, his early trainees<br />

became department chairs at half<br />

a dozen academic medical centers. He<br />

had talents and a drive beyond most,<br />

but alienated many associates and his<br />

own brother. While warm and compassionate<br />

toward patients, he could be dismissive<br />

to associates. While he was very<br />

public in much of what he did professionally,<br />

his humanitarian work was carried<br />

out with much less flourish. He was<br />

a complex and flawed man, but indeed<br />

a visionary who brought a scientific<br />

rigor to the practice of oncology and<br />

helped move Hodgkin’s disease from an<br />

untreatable malignancy to one for which<br />

cure is now the rule. Dr. Jacobs’ book is<br />

a riveting read, meticulously covering a<br />

time of dramatic creativity in American<br />

medicine while also revealing the personal<br />

infighting that took place behind<br />

the scenes.<br />

Dr. Rogoway is a member of the editorial<br />

board of <strong>The</strong> <strong>Pharos</strong> and emeritus adjunct<br />

clinical professor of Medicine at Stanford<br />

University. His address is:<br />

266 Old Spanish Trail<br />

Portola Valley, California 94028<br />

E-mail: rogoway@stanford.edu<br />

<strong>The</strong> National Institutes of<br />

Health: 1991–2008<br />

John Kastor<br />

New York, Oxford University Press,<br />

2010, 271 pages<br />

Reviewed by Jack Coulehan, MD<br />

(AΩA, University of Pittsburgh, 1969)<br />

W hen I did my internship at the<br />

Hospital of the University of<br />

Pennsylvania, John Kastor was a rising<br />

star in Penn’s Division of Cardiology.<br />

He was also one of my favorite attending<br />

physicians, partly because of excellent<br />

teaching and obvious commitment to<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 49


Reviews and reflections<br />

patients, but also because of his compassion<br />

for students and house officers. At<br />

the end of my rotation with Dr. Kastor,<br />

he invited our whole team to his home<br />

for dinner. And a splendid evening it<br />

was! I remember that dinner as an island<br />

of warmth and conviviality in the<br />

often turbulent sea of internship. Since<br />

then, Kastor has become one of the nation’s<br />

most prominent cardiologists and<br />

a leading figure in American medical<br />

education. He is the author of several<br />

important books on academic medicine,<br />

including Governance of Teaching<br />

Hospitals (2003), Specialty Care in<br />

the Era of Managed Care (2005), and<br />

Selling Teaching Hospitals and Practice<br />

Plans (2008). <strong>The</strong>se works focus, in particular,<br />

on issues of governance in large<br />

health care institutions.<br />

In his new book, <strong>The</strong> National<br />

Institutes of Health: 1991–2009, Kastor<br />

turns his attention to “the premier organization<br />

for performing and funding<br />

biomedical research in the United<br />

States.” pxi <strong>The</strong> book is primarily a description<br />

of the structure, function, mission,<br />

finances, and priorities of the NIH<br />

over nearly two decades, a period that<br />

spans the terms of three NIH directors:<br />

Bernadine Healy, Harold Varmus, and<br />

Elias Zerhouni. While the author presents<br />

plenty of “hard” historical facts,<br />

the real energy of his book arises from<br />

its human perspective: 222 interviews<br />

of present and past NIH administrators<br />

and scientists and other knowledgeable<br />

observers, conducted over a nearly<br />

two-year period. <strong>The</strong> text relies heavily—and<br />

appropriately—on quotations<br />

from these interviews, which provide<br />

the reader with a sense of living history.<br />

<strong>The</strong> NIH consists of twenty research<br />

Institutes and seven Centers, five of<br />

which serve as providers of infrastructure<br />

and support for the institutes. <strong>The</strong><br />

NIH budget in 2008 was around $29<br />

billion, eighty-five percent of which<br />

supported extramural research, i.e.,<br />

grants to universities, hospitals, and<br />

laboratories throughout the United<br />

States. Another ten percent funded the<br />

intramural research program, which<br />

employs over one thousand scientists<br />

at its Bethesda campus, as well as a<br />

large number of trainees. <strong>The</strong> final five<br />

percent of the budget was devoted to<br />

administration. <strong>The</strong> individual research<br />

Institutes range in size from the enormous<br />

National Cancer Institute (NCI,<br />

$4.8 billion budget) and National Heart,<br />

Lung and Blood Institute (NHLBI, $2.9<br />

billion) to the tiny National Institute for<br />

Nursing Research (NINR, $139 million).<br />

It requires over seventy separate administrative<br />

entities—and their acronyms—<br />

to fully characterize the structure and<br />

governance of the NIH. Fortunately, the<br />

reader need not internalize most of this<br />

alphabet soup to gain a basic understanding<br />

of the organization, although<br />

for the interested masochist Kastor provides<br />

an appendix listing every single<br />

acronym and its meaning.<br />

As an academic physician, I found<br />

some of the trends described in <strong>The</strong><br />

National Institutes of Health especially<br />

interesting. First, although I was aware<br />

that the NIH budget had grown in<br />

the 1990s, I had no idea of how much.<br />

During the six-year period 1998 through<br />

2003, its budget more than doubled<br />

from $13.6 to $27.1 billion, an average<br />

increase of about fifteen percent per<br />

year. Even more amazing was the sustained<br />

average annual eight and a half<br />

percent increase over the preceding<br />

twenty-seven years (1971–1997). On the<br />

other hand, during most of the Bush era<br />

(2003 through 2008), the NIH budget,<br />

when corrected for inflation, suffered an<br />

annual decline.<br />

Another interesting point was the<br />

historical trend of the NIH’s intramural<br />

research training program. Kastor<br />

writes of the “yellow berets,” physicians<br />

commissioned in the United States<br />

Public Health Service and assigned to<br />

the NIH in the 1950s, ’60s and ’70s,<br />

who provided the nation with a large<br />

pool of budding physician scientists. In<br />

subsequent decades, as the doctor draft<br />

ended and NIH research training became<br />

less attractive to young physicians,<br />

the size of this pool decreased, resulting<br />

in the NIH having more difficulty<br />

recruiting physician investigators for its<br />

intramural programs. However, the NIH<br />

still provides the major source of financial<br />

support for the training of physician<br />

scientists through its Medical Scientist<br />

Training Program (MSTP), which supports<br />

MD/PhD students in medical<br />

schools throughout the country.<br />

Finally, I learned for the first rime<br />

about the “Roadmap for Medical<br />

Research,” a strategic plan developed<br />

in 2002 and 2003 by then-NIH director<br />

Elias Zerhouni. Zerhouni wrote, “It was<br />

clear to me that science had changed, but<br />

the NIH had not.” p179 A “convergence of<br />

concepts and methodologies” had made<br />

many of the traditional rigid distinctions<br />

between disciplinary Institutes outdated.<br />

Zerhouni initiated a process to answer<br />

such questions as “What are today’s<br />

scientific challenges?” and “What are<br />

the roadblocks to progress?” This led<br />

to a strategic plan, which, among other<br />

things, placed new emphasis on clinical<br />

research. Zerhouni also set aside funds<br />

for Roadmap projects, a practice later<br />

endorsed by Congress when it created<br />

the “Common Fund” as a separate pool<br />

of money to support the initiation of innovative<br />

interdisciplinary projects.<br />

In <strong>The</strong> National Institutes of Health:<br />

1991–2008, John Kastor has written a<br />

clear, concise, and highly informative<br />

book that will serve as a useful entrypoint<br />

for anyone interested in gaining<br />

a basic understanding of the structure<br />

and inner workings of the NIH. As a<br />

bonus, the book also presents a human<br />

perspective on the NIH’s recent history,<br />

with fascinating insights on the process,<br />

as well as examples of the content, of<br />

NIH intramural research.<br />

Dr. Coulehan is a book review editor for<br />

<strong>The</strong> <strong>Pharos</strong> and a member of its editorial<br />

board. His address is:<br />

Center for Medical Humanities, Compassionate<br />

Care, and Bioethics<br />

HSC L3-080<br />

State University of New York at Stony<br />

Brook<br />

Stony Brook, New York 11794-8335<br />

E-mail: jcoulehan@notes.cc.sunysb.edu<br />

50 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong>


Letters to the editor<br />

���������������������������������������������� �����������<br />

Edward D. Harris, M.D.<br />

1937 — 2010<br />

����������� ����������������<br />

Poetry and Ted Harris<br />

I never met Ted Harris. Never spoke<br />

a single word to him. I only knew him<br />

as the editor of a journal I enjoyed<br />

reading. About ten years ago, I sent Dr.<br />

Harris a letter expressing my desire to<br />

serve on <strong>The</strong> <strong>Pharos</strong> editorial board.<br />

I practice and teach internal medicine<br />

in a small community in Central<br />

Virginia. Although I’ve been interested<br />

in the humanities since college, there<br />

was little in my CV to suggest I was<br />

qualified to serve. He did not grant<br />

me a position, but asked me to review<br />

submissions. I accepted. I was eager to<br />

review articles on history, philosophy,<br />

and literature.<br />

Every few months, Ted would send<br />

me a poem. I waited for essays to be<br />

sent; they never came. What did I<br />

know about poetry? Not much. As<br />

soon as a poem arrived, I analyzed the<br />

poem as best I could and immediately<br />

returned it. This went on for years. I<br />

began to study poetry, and read it<br />

every day.<br />

You know how the story<br />

ends. Ted (and Debbie<br />

Lancaster) gave me<br />

a position on the<br />

board in 2004.<br />

It’s been a wonderfully rewarding experience,<br />

and I’m forever grateful.<br />

Ted gave me something else: poetry.<br />

He also showed me how to open<br />

academic doors for others.<br />

Dean Gianakos, MD<br />

Lynchburg Family Medicine Residency<br />

Lynchburg, Virginia<br />

Vicarious respect for Ted Harris<br />

I only met Dr. Harris briefly, and<br />

that was unrelated to medicine. I barely<br />

knew him personally, yet I think I had<br />

an insight many did not. Imagine my<br />

surprise when receiving this summer’s<br />

<strong>Pharos</strong>, and immediately recognizing<br />

him on the cover. Needless to say, I was<br />

a little stunned, as this to me was so<br />

unexpected.<br />

Let me backtrack a little to the early<br />

1960s. I had recently moved with my<br />

parents to a small bedroom community<br />

on the West Shore of Harrisburg,<br />

Pennsylvania. My Latin teacher that<br />

year was a stern taskmaster, the way it<br />

used to be—and perhaps should still<br />

be. No nonsense was tolerated, and total<br />

respect was demand by Mrs. Harris.<br />

Somehow I survived. By my senior<br />

year, I had enough seniority to get a<br />

coveted paper route. By chance, she<br />

became my customer. She lived alone<br />

in a modest home that had a large, flat<br />

front yard. More on that later. I eventually<br />

graduated from Camp Hill High<br />

School, some ten years after her son<br />

had.<br />

Fast forward to my general surgery<br />

residency in 1975 at the Dartmouth<br />

Affiliated Hospitals in Hanover, New<br />

Hampshire, and White River Junction,<br />

Vermont. In those days, residents<br />

were indeed residents. We leaped at<br />

any chance to do something “normal,”<br />

and the annual medical school tennis<br />

tournament was just that excuse. My<br />

doubles partner and I were soundly<br />

defeated in the first round by none<br />

other than Ted Harris, that being my<br />

only personal encounter. Soon after<br />

that, though, he brought his mother to<br />

live in Hanover. She would often visit<br />

and go shopping with my wife, also a<br />

Camp Hill alumna. Mrs. Harris proved<br />

to be hugely independent, intelligent,<br />

and quite friendly, all surprising attributes<br />

considering my opinion as an<br />

adolescent. By the way, she informed<br />

us, her front yard had been a grass tennis<br />

court, where her son had learned<br />

the game well, permitting our paths to<br />

eventually cross.<br />

Can it be just a coincidence how<br />

all our lives are intertwined in some<br />

way? <strong>The</strong> passing of Dr. Harris abruptly<br />

engendered in me a fear of my own<br />

mortality. Yet is only DNA immortal<br />

as it passes from one generation to the<br />

next? I think not. <strong>The</strong> human lives we<br />

as physicians and teachers touch and<br />

influence daily, no matter how briefly,<br />

in some intangible way create another<br />

pathway to gain a sense of immortality,<br />

through their achievements as well. We<br />

both came from a small town, yet Ted<br />

Harris rose from humble beginnings to<br />

achieve grander things, to change the<br />

lives of many. His revitalized <strong>Pharos</strong><br />

became an extension of his personality<br />

that again influenced me later as a “senior”<br />

attending. Hopefully, it will survive<br />

his loss. <strong>The</strong> world will be a lesser<br />

place without him.<br />

Geoffrey G. Hallock, MD<br />

(AΩA, Jefferson Medical College, 1975)<br />

Allentown, Pennsylvania<br />

<strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> <strong>2011</strong> 51


Instructions for <strong>Pharos</strong> authors<br />

We welcome material that addresses scholarly and nontechnical<br />

topics in medicine and public health such as history,<br />

biography, health services research, ethics, education,<br />

and social issues. Poetry is welcome, as well as photograph/<br />

poetry combinations. Photography and art may also be<br />

submitted. Scholarly fiction is accepted. All submissions are<br />

subject to editorial board review. Contributors need not be<br />

members of <strong>Alpha</strong> <strong>Omega</strong> <strong>Alpha</strong>. Papers by medical students<br />

and residents are particularly welcome.<br />

Submissions must meet the following criteria:<br />

1. Submissions may not have been published elsewhere<br />

or be under review by another journal.<br />

2. Essays should have a maximum of 15 pages (approximately<br />

5000 words), and be submitted in 12-point<br />

type, double-spaced, with one-inch margins. <strong>The</strong>y should<br />

be accompanied by a covering letter and a title page with<br />

the word count (or page count), return address, and e-mail<br />

address. Papers exceeding the page count noted will be<br />

returned to the author. References should not exceed 20<br />

unique items (see below).<br />

3. Poems or photograph/poetry combinations should be<br />

in 12-point type, with one-inch margins, with the author’s<br />

name, address, and e-mail address on the first page.<br />

4. Electronic submissions are preferred. Send them to<br />

info@alphaomegaalpha.org. Or send by mail to Richard L.<br />

Byyny, MD, Editor of <strong>The</strong> <strong>Pharos</strong>, 525 Middlefield Road,<br />

Suite 130, Menlo Park, California 94025.<br />

5. After peer review, comments on the manuscript will<br />

be sent to the author along with an editorial decision. Every<br />

attempt is made to complete preliminary reviews within six<br />

weeks.<br />

6. <strong>The</strong> editors of <strong>The</strong> <strong>Pharos</strong> will edit all manuscripts<br />

that are accepted for publication for style, usage, relevance,<br />

felicity, and grace of expression, and may provide appropriate<br />

illustrative material. Authors should not purchase illustrative<br />

material because the editors cannot guarantee that it<br />

will be used.<br />

7. In accordance with revised copyright laws, each contributor<br />

will need to sign an Author’s Agreement, which will<br />

be sent with the edited galleys. Information on copyright<br />

ownership and re- publication of articles is detailed in the<br />

Author’s Agreement.<br />

Reference information<br />

Authors are responsible for the accuracy of citations and<br />

quotations in their papers. Once a manuscript has been accepted<br />

for publication, therefore, the author will be required<br />

to provide photocopies of all direct quotations from the<br />

primary source material, indicating page numbers. (Please<br />

mark the quoted material on the photocopies with highlighter.)<br />

In addition, the editors will require photocopies of<br />

all references: the title page and copyright pages of all books<br />

cited, the first and last pages of book chapters cited, and the<br />

first and last pages of journal articles cited, as well as the<br />

Table of Contents of the particular issue of the journal in<br />

which the cited article appeared. <strong>The</strong> foregoing items will be<br />

used to verify the accuracy of the quotations in the text and<br />

the references cited, and to correct any errors or omissions.<br />

<strong>The</strong> photocopies will not be returned.<br />

References should be double-spaced, numbered consecutively<br />

in the text, and cited at the end in the following<br />

standard form:<br />

Journal: Zilm DH, Sellers EM, MacLeod SM, Degani N.<br />

Propranolol effect on tremor in alcoholic withdrawal. Ann<br />

Intern Med 1975; 83: 234–36.<br />

Book: Harris ED Jr. Rheumatoid Arthritis. Philadelphia:<br />

WB Saunders; 1997.<br />

Book chapter: Pelligrini CA . Postoperative<br />

Complications. In: Way LW, editor. Current Surgical<br />

Diagnosis and Treatment, Ninth <strong>Edition</strong>. Norwalk (CT):<br />

Appleton & Lange; 1991: pp 25–41.<br />

Each reference should be listed in the bibliography only<br />

once, with multiple uses of a single reference citing the same<br />

bibliography reference number. Examples are available at<br />

our web site: www.alphaomegaalpha.org.<br />

Citation of web sites as references is discouraged unless a<br />

site is the single source of the information in question or has<br />

official or academic credentials. Examples of such sites are<br />

official government web pages such as that of the National<br />

Institutes of Health. Encyclopedia sites such as britannica.<br />

com are not primary references.<br />

Leaders in American Medicine<br />

In 1967, as a result of a generous gift from Drs. David<br />

E. and Beatrice C. Seegal, <strong>Alpha</strong> <strong>Omega</strong> <strong>Alpha</strong> initiated a<br />

program of one-hour videotapes featuring interviews with<br />

distinguished American physicians and medical scientists.<br />

<strong>The</strong> collection has been donated to the National Library<br />

of Medicine, which will maintain it for permanent use by<br />

scholars visiting the library. A listing of tapes available<br />

for loan from AΩA can be found on our web site: www.<br />

alphaomegaalpha.org, or by contacting Debbie Lancaster at<br />

d.lancaster@ alphaomegaalpha.org or (650) 329-0291. Those<br />

wishing to purchase copies may do so by contacting Ms.<br />

Nancy Dosch, manager, Historical Audiovisuals, History<br />

of Medicine, Building 38, Room 1E-21, 8600 Rockville Pike,<br />

Bethesda, Maryland 20891. Telephone (301) 402-8818, e-mail<br />

nancy_dosch@nlm.nih.gov.


2 <strong>The</strong> <strong>Pharos</strong>/<strong>Winter</strong> 2008

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