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Directory of Cyclotrons used for Radionuclide Production in Member ...

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18 F RADIONUCLIDE PRODUCTION<br />

<strong>Production</strong> Typical<br />

production<br />

yield (GBq)<br />

506 512<br />

% Isotopic<br />

enrichment<br />

18 O <strong>used</strong><br />

Target Volume Usage/year Do you<br />

recycle<br />

18 OH2?<br />

18 OH2<br />

18 O2<br />

18 OH2 (g)<br />

18 O2 (l)<br />

18 O (p, n) 18 F 20 30-50% 0.9 ml 20 ml 100 30 Yes<br />

No<br />

Ne (d, α) 18 F<br />

16 O (α, x) 18 F<br />

18 F RADIOPHARMACEUTICALS PRODUCED<br />

Name<br />

Yield on batch Frequency <strong>of</strong> Used on site Distribution/<br />

(list)<br />

(GBq)<br />

production<br />

sales<br />

18<br />

FDG Purchase<br />

commercially<br />

Yes No Yes No<br />

F-DOPA, FMT 3 30 Yes x No Yes No<br />

fallypride 2 50 Yes x No Yes No<br />

Fatty acids 2 2 Yes x No Yes No<br />

11<br />

C RADIOPHARMACEUTICALS PRODUCED<br />

Name<br />

Yield on batch Frequency <strong>of</strong> Used on site Distribution/<br />

(list)<br />

(GBq)<br />

production<br />

sales<br />

SCH 23,390 2 10 Yes x No Yes No<br />

Raclopride 2 15 Yes x No Yes No<br />

PK 11195 2 15 Yes x No Yes No<br />

Methyphenidate<br />

2 15 Yes x No Yes No<br />

13 N RADIOPHARMACEUTICALS PRODUCED<br />

Name<br />

Typical yield on Frequency <strong>of</strong> Nuclear reaction <strong>used</strong> Distribution/<br />

(list)<br />

batch (GBq) production<br />

sales<br />

NH3 4 5 Protons on O-16 water Yes No x<br />

Yes No<br />

Yes No<br />

15<br />

O RADIOPHARMACEUTICALS PRODUCED<br />

Name<br />

Typical yield on batch (GBq) Frequency <strong>of</strong> production Nuclear reaction<br />

(list)<br />

<strong>used</strong><br />

Price/<br />

GBq<br />

Price/<br />

GBq<br />

Price/<br />

GBq<br />

Price/<br />

GBq<br />

OTHER ISOTOPES PRODUCED<br />

Name<br />

Yield on batch Frequency <strong>of</strong> Used on site Distribution/ Price/<br />

(list)<br />

(GBq)<br />

production<br />

sales<br />

GBq<br />

64<br />

Cu 20-40 10 Yes x No Yes x No $162/<br />

GBq<br />

67<br />

Ga Yes No Yes No<br />

86<br />

Y 2 5 Yes x No Yes No<br />

94m<br />

Tc 4 5 Yes x No Yes No<br />

103<br />

Pd Yes No Yes No<br />

111<br />

In Yes No Yes No<br />

123<br />

I<br />

Yes No Yes No<br />

124<br />

I<br />

0.2-0.4 10 Yes x No Yes x No<br />

201<br />

Tl Yes No Yes No<br />

211<br />

At Yes No Yes No<br />

[17] COMMENTS:(e.g., you may add names <strong>of</strong> additional labelled compounds/radiopharmaceuticals be<strong>in</strong>g produced)<br />

Over the period <strong>of</strong> 1971 to the present, about 120 radioisotopes have been studied, mak<strong>in</strong>g about over hundred<br />

labeled compounds. (Nickles RJ, . <strong>Production</strong> <strong>of</strong> a Broader Palette <strong>of</strong> PET Tracers. J Lab Comp<br />

Radiopharmaceuticals 46, 1-27: 2003

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