Actualités dans la gestion des syndromes coronariens aigus
Actualités dans la gestion des syndromes coronariens aigus
Actualités dans la gestion des syndromes coronariens aigus
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Clopidogrel response variability for loading doses<br />
(300 vs 600 mg)<br />
Patients (%)<br />
33<br />
30<br />
27<br />
24<br />
21<br />
18<br />
15<br />
12<br />
9<br />
6<br />
3<br />
0<br />
Resistance = 28% (300 mg)<br />
Resistance = 8% (600 mg)<br />
300 mg clopidogrel<br />
600 mg clopidogrel<br />
≤−30 (−20,−10] (0,10] (20,30] (40,50] (60,70]<br />
(−30,−20] (−10,0] (10,20] (30,40] (50,60] > 70<br />
Δ A (5 μM ADP-induced Aggregation) at 24 h<br />
Gurbel PA J Am Coll Cardiol. 2005;45:1392
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