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interTALENT UNIDEB 2017

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<strong>interTALENT</strong> <strong>UNIDEB</strong> <strong>2017</strong>. február 23-24. Debreceni Egyetem<br />

BIBLIOGRAPHY<br />

1. Miklos F et. al. (2014): New Perspectives in the<br />

Renin – Angiotensin - Aldosterone System (RAAS)<br />

I: Endogenous Angiotensin Converting Enzyme<br />

(ACE) Inhibition. Plos One. 9(4):e87843.<br />

2. Miklos F et. al. (2014): New Perspectives in the<br />

Renin – Angiotensin - Aldosterone System (RAAS)<br />

II: Albumin Suppresses Angiotensin Converting<br />

Enzyme (ACE) Activity in Human. Plos One.<br />

9(4):e87844.<br />

DISCUSSION, SUMMARY<br />

Our results rule out the lung as the source of<br />

circulating ACE. Moreover, it was found that ACE<br />

activity is endogenously controlled by inhibitors.<br />

Our data opens up a new direction in this fi eld:<br />

it suggests that cardiovascular disease may start<br />

by dysregulation of endogenous control of ACE<br />

activity. The next step of the research is therefore<br />

to identify the key elements of ACE regulation and<br />

to relate them to the clinical states of the disease.<br />

3. Miklos F et. al. (2014): New Perspectives in the<br />

Renin – Angiotensin - Aldosterone System (RAAS) III:<br />

Endogenous Inhibition of Angiotensin Converting<br />

Enzyme (ACE) Provides Protection against<br />

Cardiovascular Diseases. Plos One. 9(4):e93719.<br />

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