Diapositiva 1 - Biotecnologie Mediche, Veterinarie e Farmaceutiche

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Dolly with her surrogate mother Dolly with her first newborn, Bonnie Dolly • Born in July 1996 at the Roslin Institute in Scotland • First mammal to be cloned from an adult mammal using the nuclear transfer technique • 277 attempts were made before the experiment was successful •Dolly died in February 14, 2003 of progressive lung disease at the age of 6; whereas normal sheep can live up to 12 years of age.
Mammal Cloning allows propagation of endangered species http://www.howstuf fworks.com/cloning .htm/printable January 8, 2001 Noah, a baby bull gaur, became the first clone of an endangered animal.
Page 1 and 2: • Cellule primarie Cellule stamin
Page 3 and 4: Le cellule staminali embrionali (ES
Page 5 and 6: Jaenisch 1974: topi mutanti, framme
Page 7 and 8: Microiniezione del DNA nell’ovoci
Page 9 and 10: Selezione delle cellule staminali t
Page 11 and 12: X, gene normale X*, transgene Topo
Page 13 and 14: Transgenesi mediata da retrovirus
Page 15 and 16: Knock out Studiare la funzione di u
Page 17 and 18: Knock-out convenzionale Ricombinazi
Page 19 and 20: Knock-out condizionale Transgenesi
Page 21 and 22: Tet-off: Il transattivatore regolat
Page 23 and 24: In base alla direzione ed alla posi
Page 25: Reporter: GFP, LacZ TSP: promotore
Page 28: Molti geni sono essenziali per la v
Page 32: Transgenesi utilizzata nella produz
Page 35 and 36: Trasfezione di cellule adulte con i
Page 37 and 38: Percentuali di successi di clonazio
Page 39: Tetra 1998 - 50 mice were cloned in
Page 43 and 44: Terapia genica La terapia genica è
Page 45 and 46: 1990: primo caso di cura di SCID co
Page 47 and 48: Non virali: Metodologie del trasfer
Page 49 and 50: La sicurezza della procedura Selett
Page 53 and 54: Nel 1989 è stata approvata la prim

Diapositiva 1 - Biotecnologie Mediche, Veterinarie e Farmaceutiche

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