Farmaci antinfiammatori steroidei

Anx-1 in paw oedema test.
Oedema (ml).
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0.0
*
*
*
0 1 2 3 4 5
h.
*
*
*
*
*
*
Control
10mcg Anx-1
50mcg Anx-1
IC 50 for Anx-1 in carrageenin oedema assay is ~0.54 nmol
approximately 150x more potent than indomethacin.