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Analisi genetica del ciclo cellulare - Università degli Studi della Tuscia

Analisi genetica del ciclo cellulare - Università degli Studi della Tuscia

Analisi genetica del ciclo cellulare - Università degli Studi della Tuscia

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Screening of cdc mutants with different<br />

phenotypes identified those that initiated<br />

mitosis early<br />

If mutations that block Mitosis are cdc2 (big)……<br />

…… mutations that initiate mitosis early will be small<br />

wild type<br />

wee1<br />

Probably Regulators<br />

of mitosis<br />

Screening for such mutants,<br />

discover of the wee<br />

mutants<br />

From Nurse (2002) ChemBioChem 3:596<br />

21

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