Diapositive in formato pdf - GrG
Diapositive in formato pdf - GrG
Diapositive in formato pdf - GrG
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The cl<strong>in</strong>ical presentation of IE <strong>in</strong> elderly <strong>in</strong>dividuals may be nonspecific.<br />
Several articles have emphasized that atypical presentations of IE are<br />
quite common among elderly patients and that diagnosis is frequently<br />
delayed.<br />
The present<strong>in</strong>g manifestations of IE <strong>in</strong> the older patients are<br />
constitutional symptoms, such as lethargy, fatigue, , malaise, anorexia,<br />
and weight loss, all of which can be attributed to ag<strong>in</strong>g and other<br />
disorders that are more likely to occur among elderly persons. The febrile<br />
response is often blunted <strong>in</strong> older patients. Some elderly patients<br />
manifest worsen<strong>in</strong>g of congestive heart failure. New cardiac murmurs<br />
(caused by progressive valvular damage and valvular <strong>in</strong>competence) are<br />
highly <strong>in</strong>dicative of IE. However, approximately one-third of patients with<br />
tricuspid valve disease and patients who have only mural <strong>in</strong>volvement<br />
may not have a pathologic murmur on <strong>in</strong>itial presentation. In addition,<br />
heart murmurs <strong>in</strong> elderly <strong>in</strong>dividuals may be erroneously attributed to the<br />
underly<strong>in</strong>g valvular calcification and, therefore, neglected.<br />
Alternatively, IE <strong>in</strong> elderly persons may present with a stroke syndrome,<br />
rheumatologic compla<strong>in</strong>ts, or peripheral nervous system abnormalities.<br />
Musculoskeletal manifestations of IE <strong>in</strong>clude backache, arthralgia, septic<br />
arthritis, and osteomyelitis.