Giovanni ADDOLORATO

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Farmaci approvati in Italia (ed in USA) nel trattamento della dipendenza da alcol Farmaco Italia USA Disulfiram X X Naltrexone X X (per os) Naltrexone X (i.m.) Acamprosato X GHB X Baclofen Topiramato
Changing Attitudes About Alcoholism • The past: – Alcohol Addiction as a moral failing – Behavior to be punished – Treatment is predominately non-medical • The future: – Alcohol Addiction as a brain disease – Support for a genetic predisposition – Exposure of the brain to Alcohol produces long-lasting and/or permanent changes in neuronal gene expression and neurotransmitters – Alcohol Addiction treatment is integrated into the medical system • The present: somewhere in-between Courtesy from Bob Swift, Brown University, USA
Page 1 and 2: Trattamento farmacologico della dip
Page 3 and 4: Disulfiram alcoldeidrogenasdeidroge
Page 5 and 6: SISTEMI NEUROCEREBRALI DEL CRAVING
Page 7 and 8: Naltrexone Antagonista dei recettor
Page 9 and 10: Acamprosato • Derivato sintetico
Page 11 and 12: Metanalisi sull’efficacia di nalt
Page 13 and 14: EFFICACIA DEL GHB NEL TRATTAMENTO D
Page 15 and 16: Strategie per ridurre il rischio di
Page 17 and 18: BACLOFEN • acido β-(4-clorofenil
Page 19 and 20: STUDIO IN DOPPIO CIECO ANCOVA resul
Page 21: Profilo del trial ed outcomes del t
Page 24 and 25: Topiramato • Agonista del recetto
Page 26 and 27: Efficacia del Topiramato nel ridurr

Giovanni ADDOLORATO

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