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MODULO Facoltà di Medicina e Chirurgia Data di nascita 14 ...

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Facoltà <strong>di</strong> Me<strong>di</strong>cinae <strong>Chirurgia</strong><strong>MODULO</strong>SCHEDE PERSONALI DOCENTITEC. LAB. BIO.<strong>Data</strong><strong>14</strong>.10.2008 Pag. 51 <strong>di</strong> 54Nome e CognomeRoberta Possenti<strong>Data</strong> <strong>di</strong> <strong>nascita</strong>15-07-1955Luogo <strong>di</strong> <strong>nascita</strong>RomaAssunto ilOttobre 1984Qualifica attualeProf.Aggregarto<strong>Data</strong>Laurea, precedenti esperienze <strong>di</strong> lavoro e incarico attuale1978 Scienze Biologiche con lode1981-19821985-19861986Post Doc University of Pennsylvania USAVisiting Scientist Harvard Me<strong>di</strong>cal School USAVisiting Scientist NIH USA1984 Ricercatore UniversitarioPubblicazioni, più rilevanti, del proprio excursus accademico- Mechanism of leu-enkephalin hydrolysis in human plasma. - G. Roscetti, R. Possenti, E. Bassano, L.G. Roda. Neurochem. Res. 10, 1393<strong>14</strong>04, 1985.- Initiation of Simian Virus 40 DNA replication in vitro: Aphi<strong>di</strong>colin causes accumulation of early replicating interme<strong>di</strong>ates and allowsdetermination of the initial <strong>di</strong>rection of DNA synthesis. - R.S. Decker, M. Yamaguchi, R. Possenti, M.L. De Pamphilis. Molec. Cell. Biol. 6,3815-3825, 1986.- A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway. - R. Possenti, J.D.Eldridge, B.M. Paterson, A. Grasso, A. Levi. EMBO J. 8, 2217-2223, 1989.- The VGF protein in rat pituitary gonadotrophs and lactotrophs: sex <strong>di</strong>fferences, changes during the oestral cycles and aftergonadectomy. Ferri, G.L., R.M. Gau<strong>di</strong>o, M. Cossu, A.M. Rinal<strong>di</strong>, J.M. Polak, P. Berger and R. Possenti. Endocrinology. 136, 5: 2244-2251. 1995- Expression, processing and secretion of the neuroendocrine VGF peptides by INS-1 cells. R. Possenti, A.M. Rinal<strong>di</strong>, P. Borboni,G.L. Ferri, E. Trani and A. Levi. Endocrinology <strong>14</strong>0: 3727-3735, 1999- Isolation and characterization of VGF peptides in rat brain. E. Trani, A. Giorgi, N. Canu,, G. Amadoro, A.M.Rinal<strong>di</strong>, P.A. Halban, G.L.Ferri, R. Possenti, M.E. Schininà, and A. Levi. J. Neurochem. 81:565-74 2002- Pro-VGF-derived peptides induce penile erection in male rats: Involvement of paraventricular nitric oxide Succu S, Mascia MS,Melis T, Sanna F, Melis MR, Possenti R, Argiolas A.. Neuropharmacology. 49:1017-25. 2005- TLQP-21, a VGF-derived peptide, increases energy expen<strong>di</strong>ture and prevents the early phase of <strong>di</strong>et-induced obesity.Bartolomucci A, La Corte G, Possenti R, Locatelli V, Rigamonti AE, Torsello A, Bresciani E, Bulgarelli I, Rizzi R, Pavone F, D'AmatoFR, Severini C, Mignogna G, Giorgi A, Schininà ME, Elia G, Brancia C, Ferri GL, Conti R, Ciani B, Pascucci T, Dell'Omo G, MullerEE, Levi A, Moles A. Proc Natl Acad Sci U S A. 103:<strong>14</strong>584-9. 2006- TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cells death induced by serum and potassiumdeprivation. Severini C, Ciotti MT, Bion<strong>di</strong>ni L, Quaresima S, Rinal<strong>di</strong> AM, Levi A, Frank C, Possenti R. J Neuroch104:534-44, 2008- The VGF-derived peptide TLQP-21: A new modulatory peptide for inflammatory pain. Rizzi R, Bartolomucci A, Moles A, D'Amato F,Sacerdote P, Levi A, La Corte G, Ciotti MT, Possenti R, Pavone F. Neurosci Lett. 2008

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