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La cardiopatia ischemica - Cuorediverona.it

La cardiopatia ischemica - Cuorediverona.it

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Secondary Prevention and Long Term ManagementGoalsRenin-Angiotensin-AldosteroneSystemBlockersRecommendationsACE inhib<strong>it</strong>ors in all patients indefin<strong>it</strong>ely; start early instable, high-risk patients (ant. MI, previous MI, Killip class≥ 2 [S3 gallop, rales, radiographic CHF], LVEF < 0.40).Angiotensin receptor blockers in patients who areintolerant of ACE inhib<strong>it</strong>ors and w<strong>it</strong>h e<strong>it</strong>her clinical orradiological signs of heart failure or LVEF < 0.40.Aldosterone blockade in patients w<strong>it</strong>hout significant renaldysfunction or hyperkalemia who are already receivingtherapeutic doses of an ACE inhib<strong>it</strong>or, have LVEF ≤ 0.40,and have e<strong>it</strong>her diabetes or heart failure.

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