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Sinteza lucrării - Lorentz JÄNTSCHI

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ID1051/2007 - <strong>Sinteza</strong> <strong>lucrării</strong> - perioada 2007-2010<br />

37 de derivaţi de carbo-chinolină a căror activitate biologică de interes este doza<br />

minimă necesară pentru ca acestea să fie efective.<br />

A5: Construirea bazei de date cu cunoştinţe compus chimic - model cuantic 3D -<br />

descriptori moleculari - proprietăţi fizico-bio-chimice - activităţi terapeutice<br />

R5: Baza de cunoştinţe a fost creată, imaginea de mai sus fiind un exemplu în acest<br />

sens. Baza de date a fost concepută în următoarea structură: Tabel de date (XX_data)<br />

- stochează modelul cuantic 3D pentru moleculele setului; câte un Tabel de date<br />

pentru fiecare activitate (XX_activitate); un tabel de date conţinând relaţiile<br />

structură-activiate (XX_qsar, imaginea de mai sus)<br />

A6: Proiectarea portalului web, implementarea algoritmilor de interogare, publicarea<br />

portalului web<br />

R6: Portalul web a fost publicat: http://l.academicdirect.ro/Chemistry/SARs/MDFV/<br />

o Rezultate livrate pe etapă (prevăzute 2-ISI+2-BDI, realizate 4-ISI+4-BDI):<br />

(ISI&JCR, IF 2009 =1.7, cites=0 Sept2010 ) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA,<br />

Exact Probabilities on Confidence Limits for Binomial Samples,<br />

TheScientificWorldJOURNAL, 2010, 10:865-878<br />

(ISI&JCR, IF 2009 =1.9, cites=0 Sept2010 ) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA,<br />

Radu E. SESTRAS, A Study of Genetic Algorithm Evolution on the Lipophilicity of<br />

Polychlorinated Biphenyls, Chemistry and Biodiversity, 2010, 7(8):1978-1989<br />

(ISI&JCR, IF 2009 =2.3, cites=0 Sept2010 ) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA,<br />

Radu E. SESTRAS, Meta-heuristics on quantitative structure-activity relationships:<br />

study on polychlorinated biphenyls, Journal of Molecular Modeling, 2010, 16(2),<br />

377-386<br />

(ISI&JCR, IF 2009 =0.1, cites=0 Sept2010 ) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA,<br />

The relationship between energy calculations and boiling points of n-alkanes, Studia<br />

Universitatis Babes-Bolyai Chemia, accepted<br />

(BDI: Scopus, CABI, CAS, etc.) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA,<br />

Observation vs. Observable: Maximum Likelihood Estimations according to the<br />

Assumption of Generalized Gauss and Laplace Distributions, Leonardo Electronic<br />

Journal of Practices and Technologies, 2009, 8(15), 81-04<br />

(BDI: CABI) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA, Counting Polynomials on<br />

Regular Iterative Structures, Applied Medical Informatics, 2009, 24(1-2), 67-95<br />

(BDI: Scopus, CABI) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA, Radu E.<br />

SESTRAS, Recording Evolution Supervised by a Genetic Algorithm for Quantitative<br />

Structure-Activity Relationship Optimization, Applied Medical Informatics, 2010,<br />

26(2), 89-100<br />

(BDI: CABI, Zoological Record) <strong>Lorentz</strong> JANTSCHI, Sorana D. BOLBOACA, Mugur<br />

C. BALAN, Radu E. SESTRAS, Tendency of Evolution Supervised by Genetic<br />

Algorithms, BUSASVM-CN Horticulture, 2010, 67(1), 80-85<br />

(BDI: CABI, CAS) <strong>Lorentz</strong> <strong>JÄNTSCHI</strong>, Sorana D. BOLBOACA, Mugur C. BALAN,<br />

Radu E. SESTRAS, Mircea V. DIUDEA, Results of Evolution Supervised by<br />

Genetic Algorithms, Notulae Scientia Biologicae, 2010, 2(3), 12-15<br />

Pentru conformitate, Cluj-Napoca, la 26 Sept. 2010<br />

<strong>Lorentz</strong> <strong>JÄNTSCHI</strong>, Conf. Dr., Director proiect ID-1051/2007

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